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The map label for this gene is esxA [H]

Identifier: 221229377

GI number: 221229377

Start: 61402

End: 61689

Strand: Reverse

Name: esxA [H]

Synonym: MLBr_00049

Alternate gene names: 221229377

Gene position: 61689-61402 (Counterclockwise)

Preceding gene: 221229378

Following gene: 221229376

Centisome position: 1.89

GC content: 54.17

Gene sequence:

>288_bases
ATGATACAGGCGTGGCACTTTCCTGCCCTACAGGGTGCCGTCAACGAACTGCAAGGAAGCCAGAGCAGAATCGATGCGTT
GCTCGAGCAATGCCAAGAATCGCTCACAAAGCTGCAGAGCTCGTGGCATGGTTCCGGTAACGAGTCCTATTCGTCAGTCC
AACAACGTTTCAACCAGAACACCGAGGGAATAAACCATGCACTGGGCGACCTGGTGCAAGCAATCAATCACTCGGCTGAA
ACGATGCAACAGACCGAGGCAGGCGTCACGAGTATGTTCACCGGGTAG

Upstream 100 bases:

>100_bases
ACCGGTCCGGCGGCAACTACACCAAGACCGACGATGAAGCAAACCAATTGTTGTCCTCGAAGATGAACTTCTGATCCAAT
CACCAAGAACGGAGCATGAG

Downstream 100 bases:

>100_bases
AATACCCACGCACGAGATCGGGGCGGGCTCTACTTCAAGGGATCTCGCCCTTTTCTCGTGTGTACTGGACCACACATCTG
AAAGGCTCTCATGGCGGCCG

Product: putative secreted protein

Products: NA

Alternate protein names: ESAT-6-like protein; L-ESAT [H]

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MIQAWHFPALQGAVNELQGSQSRIDALLEQCQESLTKLQSSWHGSGNESYSSVQQRFNQNTEGINHALGDLVQAINHSAE
TMQQTEAGVTSMFTG

Sequences:

>Translated_95_residues
MIQAWHFPALQGAVNELQGSQSRIDALLEQCQESLTKLQSSWHGSGNESYSSVQQRFNQNTEGINHALGDLVQAINHSAE
TMQQTEAGVTSMFTG
>Mature_95_residues
MIQAWHFPALQGAVNELQGSQSRIDALLEQCQESLTKLQSSWHGSGNESYSSVQQRFNQNTEGINHALGDLVQAINHSAE
TMQQTEAGVTSMFTG

Specific function: Unknown

COG id: COG4842

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ESAT-6 (esx) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010310 [H]

Pfam domain/function: PF06013 WXG100 [H]

EC number: NA

Molecular weight: Translated: 10407; Mature: 10407

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQAWHFPALQGAVNELQGSQSRIDALLEQCQESLTKLQSSWHGSGNESYSSVQQRFNQN
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
TEGINHALGDLVQAINHSAETMQQTEAGVTSMFTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIQAWHFPALQGAVNELQGSQSRIDALLEQCQESLTKLQSSWHGSGNESYSSVQQRFNQN
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
TEGINHALGDLVQAINHSAETMQQTEAGVTSMFTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]