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The map label for this gene is wcaL [C]

Identifier: 220933115

GI number: 220933115

Start: 2492875

End: 2494032

Strand: Reverse

Name: wcaL [C]

Synonym: Hore_22830

Alternate gene names: 220933115

Gene position: 2494032-2492875 (Counterclockwise)

Preceding gene: 220933116

Following gene: 220933114

Centisome position: 96.74

GC content: 27.98

Gene sequence:

>1158_bases
ATGAACATATGTTTATTTTCAAGTGATTATCTCCCGAATATCGGGGGAATAGCTAATCATGTAGCAGAATTAGGGAGAGC
TTTAGTTAAATTGGGACATAATGTTGTCGTTTTTACAAAATGTAGTTTTAAAGAACAAAAAAATTTCAAGATAAACGTTG
AAGATGACAAAGGGATGAAGGTCATAAGAGTTCCTATTATTGATATTCCCAAAATTAGAGGATTGAATATGAGAATTCTA
TATTATTATTATTTAAAAAAAATATTAAAAAAGTATAGTATTGATATTTTACATTGGCATTGTTTAACTCATGATTCATA
TGTTACTAGAAAAATTAATTTTGATAATATAGTTTTTACGAATCATAGTTCAACCTTTTTACTACGAATGGAAAAGAAGG
AATATGATAGATTAAAAAAAGATATATTTCATGCAAGAGAAATTATTGCACCTAGTAAAGAACTTTGTGAAAAGACAGTA
GAGTTAGGATACCCTGTAGATAAAGTGCATTATATATCTAATGGTGTTGATTTAGATAGATTTACCCCTAATATTAATGT
TCAAGAGTTAAAAAGAGAATTAAAAATAAAACAAGATGAAAAGGTAGTTGTCTGTGCTAGAAGATTTGCCAAAAAGAATG
GTGTTATTTATTTAGTTAAAGCTATTCCTGAAATAATAAAAAGATTAAATGGAAAAATAAAGTTTGTTTTCGTTGGAGAT
TTCCCAATTGACCATCCAGAATCTGAAAAAAGAGAAATTTTAGACTACATCAATGAAGCTAGTTTAAATAAATATATCAT
ATTAACAGGTCCGATTCCTTCAGAAGATATGCCCAGATATTATTCTTTAGGTGACATTTCTGTATTACCTTCTTTAAAAG
AAGCAACTAGTTTAAGTGGATTAGAATCTATGGCATGTGGAGTACCAGTTATTGGTACAGAAGTAGGTGGGATTCCTCAA
ATAATTGAAAATCATGTTAATGGTGTTTTAGTTCCTCCAAAAAATAGTATAAAATTAGCAGATGCTATTGTAAGTATATT
ACAAGATAATAAGGAAAGGGATATTTATAGTGTAAATGCTAGAGAATTTGTTAAAGAAAATTATTCGTGGATCAGGGTAG
CCAAAGATACTCTTGATGTTTATAAAAAAATACTTTAG

Upstream 100 bases:

>100_bases
TAGCTAATAGAATTTTATATAATTATTTTTAAATTGGTTATTCATGAAAGATATAATAAGACTAAGACTAGGTATTCGAT
AAATGGGAGGATTTTTGTAA

Downstream 100 bases:

>100_bases
TTTTTTTGGGGGGATTTCTATTAAAAGAATTTTAATAATAAATGTAGAAACTCAATTTGGAGGGGCTGAAAAGTCCATAG
TGGATATATTTAAAAAAATT

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNICLFSSDYLPNIGGIANHVAELGRALVKLGHNVVVFTKCSFKEQKNFKINVEDDKGMKVIRVPIIDIPKIRGLNMRIL
YYYYLKKILKKYSIDILHWHCLTHDSYVTRKINFDNIVFTNHSSTFLLRMEKKEYDRLKKDIFHAREIIAPSKELCEKTV
ELGYPVDKVHYISNGVDLDRFTPNINVQELKRELKIKQDEKVVVCARRFAKKNGVIYLVKAIPEIIKRLNGKIKFVFVGD
FPIDHPESEKREILDYINEASLNKYIILTGPIPSEDMPRYYSLGDISVLPSLKEATSLSGLESMACGVPVIGTEVGGIPQ
IIENHVNGVLVPPKNSIKLADAIVSILQDNKERDIYSVNAREFVKENYSWIRVAKDTLDVYKKIL

Sequences:

>Translated_385_residues
MNICLFSSDYLPNIGGIANHVAELGRALVKLGHNVVVFTKCSFKEQKNFKINVEDDKGMKVIRVPIIDIPKIRGLNMRIL
YYYYLKKILKKYSIDILHWHCLTHDSYVTRKINFDNIVFTNHSSTFLLRMEKKEYDRLKKDIFHAREIIAPSKELCEKTV
ELGYPVDKVHYISNGVDLDRFTPNINVQELKRELKIKQDEKVVVCARRFAKKNGVIYLVKAIPEIIKRLNGKIKFVFVGD
FPIDHPESEKREILDYINEASLNKYIILTGPIPSEDMPRYYSLGDISVLPSLKEATSLSGLESMACGVPVIGTEVGGIPQ
IIENHVNGVLVPPKNSIKLADAIVSILQDNKERDIYSVNAREFVKENYSWIRVAKDTLDVYKKIL
>Mature_385_residues
MNICLFSSDYLPNIGGIANHVAELGRALVKLGHNVVVFTKCSFKEQKNFKINVEDDKGMKVIRVPIIDIPKIRGLNMRIL
YYYYLKKILKKYSIDILHWHCLTHDSYVTRKINFDNIVFTNHSSTFLLRMEKKEYDRLKKDIFHAREIIAPSKELCEKTV
ELGYPVDKVHYISNGVDLDRFTPNINVQELKRELKIKQDEKVVVCARRFAKKNGVIYLVKAIPEIIKRLNGKIKFVFVGD
FPIDHPESEKREILDYINEASLNKYIILTGPIPSEDMPRYYSLGDISVLPSLKEATSLSGLESMACGVPVIGTEVGGIPQ
IIENHVNGVLVPPKNSIKLADAIVSILQDNKERDIYSVNAREFVKENYSWIRVAKDTLDVYKKIL

Specific function: Slime polysaccharide colanic acid biosynthesis. [C]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=399, Percent_Identity=25.8145363408521, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI1788357, Length=238, Percent_Identity=23.5294117647059, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17532709, Length=393, Percent_Identity=24.9363867684478, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI9755344, Length=393, Percent_Identity=23.6641221374046, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24654571, Length=348, Percent_Identity=25.8620689655172, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR013534 [H]

Pfam domain/function: PF08323 Glyco_transf_5; PF00534 Glycos_transf_1 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 44157; Mature: 44157

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNICLFSSDYLPNIGGIANHVAELGRALVKLGHNVVVFTKCSFKEQKNFKINVEDDKGMK
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCCCCE
VIRVPIIDIPKIRGLNMRILYYYYLKKILKKYSIDILHWHCLTHDSYVTRKINFDNIVFT
EEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEECCCEEEEE
NHSSTFLLRMEKKEYDRLKKDIFHAREIIAPSKELCEKTVELGYPVDKVHYISNGVDLDR
CCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHEEHCCCCCCHHH
FTPNINVQELKRELKIKQDEKVVVCARRFAKKNGVIYLVKAIPEIIKRLNGKIKFVFVGD
CCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHCCCEEEEHHHHHHHHHHHCCCEEEEEEEC
FPIDHPESEKREILDYINEASLNKYIILTGPIPSEDMPRYYSLGDISVLPSLKEATSLSG
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCHHHHHHHCC
LESMACGVPVIGTEVGGIPQIIENHVNGVLVPPKNSIKLADAIVSILQDNKERDIYSVNA
HHHHHCCCCEECCCCCCHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCH
REFVKENYSWIRVAKDTLDVYKKIL
HHHHHCCCCEEEEHHHHHHHHHHHC
>Mature Secondary Structure
MNICLFSSDYLPNIGGIANHVAELGRALVKLGHNVVVFTKCSFKEQKNFKINVEDDKGMK
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCCCCE
VIRVPIIDIPKIRGLNMRILYYYYLKKILKKYSIDILHWHCLTHDSYVTRKINFDNIVFT
EEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEECCCEEEEE
NHSSTFLLRMEKKEYDRLKKDIFHAREIIAPSKELCEKTVELGYPVDKVHYISNGVDLDR
CCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHEEHCCCCCCHHH
FTPNINVQELKRELKIKQDEKVVVCARRFAKKNGVIYLVKAIPEIIKRLNGKIKFVFVGD
CCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHCCCEEEEHHHHHHHHHHHCCCEEEEEEEC
FPIDHPESEKREILDYINEASLNKYIILTGPIPSEDMPRYYSLGDISVLPSLKEATSLSG
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCHHHHHHHCC
LESMACGVPVIGTEVGGIPQIIENHVNGVLVPPKNSIKLADAIVSILQDNKERDIYSVNA
HHHHHCCCCEECCCCCCHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCH
REFVKENYSWIRVAKDTLDVYKKIL
HHHHHCCCCEEEEHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]