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The map label for this gene is mltD [C]

Identifier: 220933056

GI number: 220933056

Start: 2424266

End: 2426125

Strand: Reverse

Name: mltD [C]

Synonym: Hore_22240

Alternate gene names: 220933056

Gene position: 2426125-2424266 (Counterclockwise)

Preceding gene: 220933057

Following gene: 220933050

Centisome position: 94.1

GC content: 38.66

Gene sequence:

>1860_bases
TTGCTTTTCTTTAAGAATAGGTCAGAGTTGTTGTTATTAATTATAATAATGTTTTTGTGTGTTACTTCCGTCAGCCATGC
AGCTGAAATGGTTAAAAAACAGGATATAGTTGATTATCAGTTACATAAAGTCAAATCAGGAGAGACCCTGTGGTTTTTAT
CAGGCAAATATGGAGTTCCTATAAAGCATATAAAAGATTTTAATGGTCTAAAGAGCACCAGGATAAAGCAGGGTCAGACA
CTTAAAATACCGTATTTTAAAACACTATATTTAATTAAAATAAATAAAGGGGATACCCTCTGGTCTGTTTCCCGCCAGTT
TAAGACTACAGTAGAGGAGATAAAGCAGTTTAACAGCCTTACCGTTAATACAATTTACCCGGGACAGCACCTGGTTTTAA
TTAAGGATAAACCAGATAACTTTTATCCCACTGGAGAGCTACCGACCTGGCAAGAAGTTTTTATAAACTGGAAGGAAAAT
TACTGGATTATCAAGACAATAAAAGAATTAACCCCTGATGAGAAGGCAAAAGAACAGCTGGACGACCGGATAACAAGGAA
AGATTCCCTGACCAGAGCAGAACTGGCTGTTATGGTAGAGCAGATACTGGACAGGCTGGAAGAACAGGAAGAGATGGATA
ATACCCTGGAAGAGAAAATAACCCTGGACCGGGATAATGTTGACCAGCTTTACAGTATTGTACAGCTTTTACATGATGAG
CTCGTTGAAATGGGGGTTAAGGTAAATAAAGTTGAGAAAAACCTTAAAACCCTGGATACAGAAATGGGTAAAGAACTTAC
CGGTGTTAAACAGGATGTTACTGGCCTTAAAAGTGATGTTGGCTTAATTGAAAAGGAAGTGGAGAAAGAGCGGGAGATTA
CAAGGAATTATAATCAGTTTAGGATAAGTGGTTTTACCAGGTTGGACTATACTAAAGACCTGATAAATAATAATCTTGAC
CCGGCTATAAGCCAGACTTTCTTCTTCAATGCCAATACTGTTTTAAGTAGCCAGAAGCAAATAAACTTCTTCCTCGAGGC
TGATTATATTCTGGATCAGGGAACAGATATTAAAATCGGAAGTAACGGGGATTTTACCCTAAATAAACACAATAAATTTA
ATTTCACCTTTGCTCATCAACAGCCCTTTAATACTTCTACTGAAAAGCAGACTTATGTTGACCTGAATTATCTCTTGACA
ACTAAATTTATGGATCTCAATGTCCTGACTGCCCATGGTAATTATAAAACCGCGCAGGCTTCTTTGAATTCTGCCAGGGC
ACTCTTTAAAACCCCGATTATGGAGTTTGAAGCTGATTATTATAATAAAGATTACAATCTGAATTATCTCATCATCGGAA
GAGATTATTTGCCCGGGGAGAGGTATTTCAGGGACTTTATCCTTGAAGAAATTGATTTTATGGGGTATAAAGTTGTTTCG
CCCCTGGTGGTTGAAGATCACCGCGTCTTAAATCTTATGCTCCCTGTTAAGGATGTATATCGAATTACAGCCGGGCTGGA
AGAGATGGATGGTCTGAGTGGAACCGTTATTGGGTTGAGAAAAGAAGGCAAACCATGGGACATGAGGGTTGACTACCTGT
TCTGGGAGGATAAGGCCTTACTGGACCGGACCCTGCGTTCAGAGTTTAATTTTAAATATGCCTTATTTAACTTTGGTTTA
GACCTCTATTACACCTGGGCTGATGAAACACTGATGACAAATCGTTACATGACAGAAGTAGGCCTTGAACTAACAGATTA
CCTTAAAGCAGAGCTGGCATATACAAAAGAAAAGGTAAAATCCGGGGTTGCTCTTCCGGAATTAGAATATATGGGCATGG
GGTTAGAATTCCGGTTTTAA

Upstream 100 bases:

>100_bases
AAAAATATAATAAGTTGTAGAAGTATTAGAAGTAAGGTTGTATTATTGTATGTTTTTATAGTATTTTTTTAGATATATTT
TATAGAAGGGAGTGAAGTTT

Downstream 100 bases:

>100_bases
GTGTCAATGACGGGAGGTACTGGTATAAAAGGCAACTGTAATTATAGAATAAGAAATGTAATTATAGAATAAGAAAGAAA
AAATATAAAATTAATAAAAA

Product: Peptidoglycan-binding LysM

Products: 1,6-Anhydrobond In The Muramic Acid Residue [C]

Alternate protein names: Cell Wall Hydrolase SleB; Glycoside Hydrolase Family; Lytic Transglycosylase Catalytic; Slt Family Transglycosylase; Peptidase S8 And; Gamma-D-Glutamate-Meso-Diaminopimelate Muropeptidase; LysM Repeat-Containing Protein

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MLFFKNRSELLLLIIIMFLCVTSVSHAAEMVKKQDIVDYQLHKVKSGETLWFLSGKYGVPIKHIKDFNGLKSTRIKQGQT
LKIPYFKTLYLIKINKGDTLWSVSRQFKTTVEEIKQFNSLTVNTIYPGQHLVLIKDKPDNFYPTGELPTWQEVFINWKEN
YWIIKTIKELTPDEKAKEQLDDRITRKDSLTRAELAVMVEQILDRLEEQEEMDNTLEEKITLDRDNVDQLYSIVQLLHDE
LVEMGVKVNKVEKNLKTLDTEMGKELTGVKQDVTGLKSDVGLIEKEVEKEREITRNYNQFRISGFTRLDYTKDLINNNLD
PAISQTFFFNANTVLSSQKQINFFLEADYILDQGTDIKIGSNGDFTLNKHNKFNFTFAHQQPFNTSTEKQTYVDLNYLLT
TKFMDLNVLTAHGNYKTAQASLNSARALFKTPIMEFEADYYNKDYNLNYLIIGRDYLPGERYFRDFILEEIDFMGYKVVS
PLVVEDHRVLNLMLPVKDVYRITAGLEEMDGLSGTVIGLRKEGKPWDMRVDYLFWEDKALLDRTLRSEFNFKYALFNFGL
DLYYTWADETLMTNRYMTEVGLELTDYLKAELAYTKEKVKSGVALPELEYMGMGLEFRF

Sequences:

>Translated_619_residues
MLFFKNRSELLLLIIIMFLCVTSVSHAAEMVKKQDIVDYQLHKVKSGETLWFLSGKYGVPIKHIKDFNGLKSTRIKQGQT
LKIPYFKTLYLIKINKGDTLWSVSRQFKTTVEEIKQFNSLTVNTIYPGQHLVLIKDKPDNFYPTGELPTWQEVFINWKEN
YWIIKTIKELTPDEKAKEQLDDRITRKDSLTRAELAVMVEQILDRLEEQEEMDNTLEEKITLDRDNVDQLYSIVQLLHDE
LVEMGVKVNKVEKNLKTLDTEMGKELTGVKQDVTGLKSDVGLIEKEVEKEREITRNYNQFRISGFTRLDYTKDLINNNLD
PAISQTFFFNANTVLSSQKQINFFLEADYILDQGTDIKIGSNGDFTLNKHNKFNFTFAHQQPFNTSTEKQTYVDLNYLLT
TKFMDLNVLTAHGNYKTAQASLNSARALFKTPIMEFEADYYNKDYNLNYLIIGRDYLPGERYFRDFILEEIDFMGYKVVS
PLVVEDHRVLNLMLPVKDVYRITAGLEEMDGLSGTVIGLRKEGKPWDMRVDYLFWEDKALLDRTLRSEFNFKYALFNFGL
DLYYTWADETLMTNRYMTEVGLELTDYLKAELAYTKEKVKSGVALPELEYMGMGLEFRF
>Mature_619_residues
MLFFKNRSELLLLIIIMFLCVTSVSHAAEMVKKQDIVDYQLHKVKSGETLWFLSGKYGVPIKHIKDFNGLKSTRIKQGQT
LKIPYFKTLYLIKINKGDTLWSVSRQFKTTVEEIKQFNSLTVNTIYPGQHLVLIKDKPDNFYPTGELPTWQEVFINWKEN
YWIIKTIKELTPDEKAKEQLDDRITRKDSLTRAELAVMVEQILDRLEEQEEMDNTLEEKITLDRDNVDQLYSIVQLLHDE
LVEMGVKVNKVEKNLKTLDTEMGKELTGVKQDVTGLKSDVGLIEKEVEKEREITRNYNQFRISGFTRLDYTKDLINNNLD
PAISQTFFFNANTVLSSQKQINFFLEADYILDQGTDIKIGSNGDFTLNKHNKFNFTFAHQQPFNTSTEKQTYVDLNYLLT
TKFMDLNVLTAHGNYKTAQASLNSARALFKTPIMEFEADYYNKDYNLNYLIIGRDYLPGERYFRDFILEEIDFMGYKVVS
PLVVEDHRVLNLMLPVKDVYRITAGLEEMDGLSGTVIGLRKEGKPWDMRVDYLFWEDKALLDRTLRSEFNFKYALFNFGL
DLYYTWADETLMTNRYMTEVGLELTDYLKAELAYTKEKVKSGVALPELEYMGMGLEFRF

Specific function: Murein-Degrading Enzyme. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division (By Similarity). [C]

COG id: COG1388

COG function: function code M; FOG: LysM repeat

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 72324; Mature: 72324

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFFKNRSELLLLIIIMFLCVTSVSHAAEMVKKQDIVDYQLHKVKSGETLWFLSGKYGVP
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCEEEEECCCCCCC
IKHIKDFNGLKSTRIKQGQTLKIPYFKTLYLIKINKGDTLWSVSRQFKTTVEEIKQFNSL
HHHHHCCCCCCHHHCCCCCEEECCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCE
TVNTIYPGQHLVLIKDKPDNFYPTGELPTWQEVFINWKENYWIIKTIKELTPDEKAKEQL
EEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHHEEECCCEEEEEEHHHCCCCHHHHHHH
DDRITRKDSLTRAELAVMVEQILDRLEEQEEMDNTLEEKITLDRDNVDQLYSIVQLLHDE
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHH
LVEMGVKVNKVEKNLKTLDTEMGKELTGVKQDVTGLKSDVGLIEKEVEKEREITRNYNQF
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RISGFTRLDYTKDLINNNLDPAISQTFFFNANTVLSSQKQINFFLEADYILDQGTDIKIG
EEECEEECCHHHHHHCCCCCCCHHCEEEEECCHHCCCCCEEEEEEEEEEEECCCCEEEEC
SNGDFTLNKHNKFNFTFAHQQPFNTSTEKQTYVDLNYLLTTKFMDLNVLTAHGNYKTAQA
CCCCEEEECCCEEEEEEECCCCCCCCCCCEEEEEEEEEEEEEEEEEEEEEECCCCEEHHH
SLNSARALFKTPIMEFEADYYNKDYNLNYLIIGRDYLPGERYFRDFILEEIDFMGYKVVS
HHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHC
PLVVEDHRVLNLMLPVKDVYRITAGLEEMDGLSGTVIGLRKEGKPWDMRVDYLFWEDKAL
CCEECCCEEEEEECCHHHHHHHHHCHHHHCCCCEEEEEEECCCCCCCEEEEEEEECCHHH
LDRTLRSEFNFKYALFNFGLDLYYTWADETLMTNRYMTEVGLELTDYLKAELAYTKEKVK
HHHHHHHHCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SGVALPELEYMGMGLEFRF
CCCCCCCHHHHCCCEEECC
>Mature Secondary Structure
MLFFKNRSELLLLIIIMFLCVTSVSHAAEMVKKQDIVDYQLHKVKSGETLWFLSGKYGVP
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCEEEEECCCCCCC
IKHIKDFNGLKSTRIKQGQTLKIPYFKTLYLIKINKGDTLWSVSRQFKTTVEEIKQFNSL
HHHHHCCCCCCHHHCCCCCEEECCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCE
TVNTIYPGQHLVLIKDKPDNFYPTGELPTWQEVFINWKENYWIIKTIKELTPDEKAKEQL
EEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHHEEECCCEEEEEEHHHCCCCHHHHHHH
DDRITRKDSLTRAELAVMVEQILDRLEEQEEMDNTLEEKITLDRDNVDQLYSIVQLLHDE
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHH
LVEMGVKVNKVEKNLKTLDTEMGKELTGVKQDVTGLKSDVGLIEKEVEKEREITRNYNQF
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RISGFTRLDYTKDLINNNLDPAISQTFFFNANTVLSSQKQINFFLEADYILDQGTDIKIG
EEECEEECCHHHHHHCCCCCCCHHCEEEEECCHHCCCCCEEEEEEEEEEEECCCCEEEEC
SNGDFTLNKHNKFNFTFAHQQPFNTSTEKQTYVDLNYLLTTKFMDLNVLTAHGNYKTAQA
CCCCEEEECCCEEEEEEECCCCCCCCCCCEEEEEEEEEEEEEEEEEEEEEECCCCEEHHH
SLNSARALFKTPIMEFEADYYNKDYNLNYLIIGRDYLPGERYFRDFILEEIDFMGYKVVS
HHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHC
PLVVEDHRVLNLMLPVKDVYRITAGLEEMDGLSGTVIGLRKEGKPWDMRVDYLFWEDKAL
CCEECCCEEEEEECCHHHHHHHHHCHHHHCCCCEEEEEEECCCCCCCEEEEEEEECCHHH
LDRTLRSEFNFKYALFNFGLDLYYTWADETLMTNRYMTEVGLELTDYLKAELAYTKEKVK
HHHHHHHHCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SGVALPELEYMGMGLEFRF
CCCCCCCHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA