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The map label for this gene is purQ [H]

Identifier: 220933046

GI number: 220933046

Start: 2412335

End: 2413042

Strand: Reverse

Name: purQ [H]

Synonym: Hore_22140

Alternate gene names: 220933046

Gene position: 2413042-2412335 (Counterclockwise)

Preceding gene: 220933047

Following gene: 220933045

Centisome position: 93.6

GC content: 43.36

Gene sequence:

>708_bases
ATGAAATTTGGAGTAATTGTATTTCCAGGTTCCAACTGTGACCGGGACTGTTATCATGTGACTGCCCGGGTACTGGGAGA
GCCGACCGAGTTTATCTGGCATGAAGATGATCGTTCCCTTGCCGGTTATGATTGTATCATTATCCCCGGTGGTTTTTCCT
ACGGGGATTACCTCAGGGCAGGCGCCATTGCCAGGTTTGCCCCGGTTATGGAACGGGTTAAGGAATTTGCCCGAAAGGGA
GGATTAGTAATCGGTATCTGTAATGGCTTTCAGATTTTACTGGAGGCAGGGCTTTTGCCCGGGGCCATGCATCATAATGC
CCACCTTAATTTTAACTGCCGGTATGTTTATTTAAGGGTTGAAAATAATAAGACTCCCTTTACAGGTAAGTTCAATAAAG
GAGATATAATAAATCTCCCTGTTGCCCATAAAGAGGGTAACTATTATATAGATGACAGGGGTTTAGAGGAATTGAAGGAA
AATAACCAGATTATATTAAGGTACGCAACGCCGGGGGGAGAGGTTATAGATGAAGCCAATCCTAATGGTTCAATCGGTAA
TATTGCCGGCATTACCAATAAAAATCATAATGTATTTGGGCTTATGCCCCATCCTGAAAGGGCCAGTGAAACCATTCTCG
GTAATGGGAGTGACGATGGACTTAAAATATTTCAATCAATTCTTAAGGCTGGTGGTGTGAAACTATGA

Upstream 100 bases:

>100_bases
TTAAAAGGGCTGAGGAGACCGCCGGCCGAATTCTGGCCAATCCAGTTATCGAAGATTATAAAGTTGAAGTAAAAAAAGCC
AATTAAATGGGAGTGGTTTT

Downstream 100 bases:

>100_bases
AATCCCGGGAACAACTATTAGAAAAGCTAAAATTTCACGGACTTACTGAAAAAGAGTATCACATGATTGTTGAAAAACTG
GGGAGAGAGCCCAATGAACT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKFGVIVFPGSNCDRDCYHVTARVLGEPTEFIWHEDDRSLAGYDCIIIPGGFSYGDYLRAGAIARFAPVMERVKEFARKG
GLVIGICNGFQILLEAGLLPGAMHHNAHLNFNCRYVYLRVENNKTPFTGKFNKGDIINLPVAHKEGNYYIDDRGLEELKE
NNQIILRYATPGGEVIDEANPNGSIGNIAGITNKNHNVFGLMPHPERASETILGNGSDDGLKIFQSILKAGGVKL

Sequences:

>Translated_235_residues
MKFGVIVFPGSNCDRDCYHVTARVLGEPTEFIWHEDDRSLAGYDCIIIPGGFSYGDYLRAGAIARFAPVMERVKEFARKG
GLVIGICNGFQILLEAGLLPGAMHHNAHLNFNCRYVYLRVENNKTPFTGKFNKGDIINLPVAHKEGNYYIDDRGLEELKE
NNQIILRYATPGGEVIDEANPNGSIGNIAGITNKNHNVFGLMPHPERASETILGNGSDDGLKIFQSILKAGGVKL
>Mature_235_residues
MKFGVIVFPGSNCDRDCYHVTARVLGEPTEFIWHEDDRSLAGYDCIIIPGGFSYGDYLRAGAIARFAPVMERVKEFARKG
GLVIGICNGFQILLEAGLLPGAMHHNAHLNFNCRYVYLRVENNKTPFTGKFNKGDIINLPVAHKEGNYYIDDRGLEELKE
NNQIILRYATPGGEVIDEANPNGSIGNIAGITNKNHNVFGLMPHPERASETILGNGSDDGLKIFQSILKAGGVKL

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=215, Percent_Identity=30.2325581395349, Blast_Score=75, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=180, Percent_Identity=31.1111111111111, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24582111, Length=193, Percent_Identity=32.1243523316062, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24582109, Length=193, Percent_Identity=32.1243523316062, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17137292, Length=193, Percent_Identity=32.1243523316062, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR010075
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25852; Mature: 25852

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFGVIVFPGSNCDRDCYHVTARVLGEPTEFIWHEDDRSLAGYDCIIIPGGFSYGDYLRA
CCEEEEEECCCCCCCHHHHHHHHHHCCCHHEEEECCCCCCCCEEEEEECCCCCHHHHHHH
GAIARFAPVMERVKEFARKGGLVIGICNGFQILLEAGLLPGAMHHNAHLNFNCRYVYLRV
HHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEE
ENNKTPFTGKFNKGDIINLPVAHKEGNYYIDDRGLEELKENNQIILRYATPGGEVIDEAN
ECCCCCCCCCCCCCCEEECCEEECCCCEEECCCCHHHHHCCCEEEEEEECCCCCEEECCC
PNGSIGNIAGITNKNHNVFGLMPHPERASETILGNGSDDGLKIFQSILKAGGVKL
CCCCCCEEEEECCCCCCEEEECCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKFGVIVFPGSNCDRDCYHVTARVLGEPTEFIWHEDDRSLAGYDCIIIPGGFSYGDYLRA
CCEEEEEECCCCCCCHHHHHHHHHHCCCHHEEEECCCCCCCCEEEEEECCCCCHHHHHHH
GAIARFAPVMERVKEFARKGGLVIGICNGFQILLEAGLLPGAMHHNAHLNFNCRYVYLRV
HHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEE
ENNKTPFTGKFNKGDIINLPVAHKEGNYYIDDRGLEELKENNQIILRYATPGGEVIDEAN
ECCCCCCCCCCCCCCEEECCEEECCCCEEECCCCHHHHHCCCEEEEEEECCCCCEEECCC
PNGSIGNIAGITNKNHNVFGLMPHPERASETILGNGSDDGLKIFQSILKAGGVKL
CCCCCCEEEEECCCCCCEEEECCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA