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The map label for this gene is mcpC [H]

Identifier: 220933018

GI number: 220933018

Start: 2376050

End: 2377504

Strand: Reverse

Name: mcpC [H]

Synonym: Hore_21850

Alternate gene names: 220933018

Gene position: 2377504-2376050 (Counterclockwise)

Preceding gene: 220933019

Following gene: 220933017

Centisome position: 92.22

GC content: 35.74

Gene sequence:

>1455_bases
ATGGATAAGAAAAACGAGTTATACCAACAAAATCTTTTGTTATTAAAAATCATGTGGTTAATAACCGTAATTGGAGTCGT
GTTTTTACTTTATAGAAGTGCTCCTGTGATTATGATCACTGGTTTTACCATAACATGCCTGATTGTAAATATATTACTAA
CATTTTTAATGTGGAAAAATATCCTTACCCAGTACATACAGTATTTCATTATTGTCGGATTATCGGTTCTAGCATGGTTA
TTAATTTCCACTTCTAATAGTTTTTATAGTTACCTGATTTTATTTGCCAATCTGGTGTTGATTGCCCTTTATACTAACTA
CTGGCCAACTTTGATTATGGGGATAAGCAATTTGATTATTGTTAATTCTCTTCTGGGAGGGATAGGCAGGAACAATCTTT
TAATTATTGATTTATATCTGGTTTTAATAACTGTCCTGGTATTGACCCAGACCCATCTCCGGATTAAAATTCAGAGAAGA
ATAGATGAAAAACATCAGCAGGTCATCAAGACTGAAAAGGAAAAAGAATCTCTCTTAGAGGAAATAATGACTACTGTTAA
AGAGTTGAGCAACTTTAACTCCAGTTTGAAGGAAAACATTAAGGTAACAGACCGTATTTCCAGTGAAGTTACTAAAGCTT
TTACTGATATTGCAAAAGGTATTGAAGATCAGGCCCATAGTGTAAATGAAATAAATGAATCAGCCCGGTCCAGCAACCAT
AATGTCCGGGCCCTTGCCAGTGCTTCAAATGAAATGCTTAATTTATCTAATAAAACAGTGAATGCTACTTCAAAGGGGAA
TGAACAGGTAGACCTTCTTGATACCAAGATGCAGGATGTTGATCAGATTATAAATGAGAGTGTTGACCTTATTAATAGAT
TAAATGAACAGGCCCAGCAAATAGGTGATATTGTAGAAACCATTAATAATATAGCCAAACAGACTAATCTTCTGGCTTTA
AACGCAGCTATAGAGGCAGCCCGGGCCGGGGAAGCAGGTCAGGGTTTTGCTGTGGTGGCCGACGAAATACGTGAACTGGC
TGAAGATTCTCACCGTTCTACTGATAAAATTGCCTCTATACTGCAGGATATTAAAGCCAAAACAGGACAGGTAACTGAGC
AGATAAATATCGGTCATGATGCTGTTTTATCAAGCAAGAACTCTACTGAAGAAGTAAAAAGAGTATTTAAAGAGATTGAT
GATAATACTAAAAATGTAGTAGAACAGGCTCAATACCTGGAAGAATCAGTAAGGGGCCTGGAGAAGGAATCACAGGCAAT
TGTTGAAGAAATATCTTCTATTTCCAGTATTATCGAGGAAACATCTGCTTCTGTTGAAGAAGTACTGGCCGGGAGTGAAG
AACAGACAAATAAAGTTAAAAATATAGTAGAAAGCTTTAAACAACTGGATAAACTAATTAATAAGTTACAGAGTTTAACT
AAAGGAGGTAGCTAA

Upstream 100 bases:

>100_bases
CTGGTTATGGCAGGAATTCTACATACTTCACAAAAAAGATTATTTTTGGTATAATATTTAAAAAATAATAACAATTTTCT
CAATATAAAGGGGTGGGTCT

Downstream 100 bases:

>100_bases
AATTTCCGGACAAAAAAATAAACCGACTGTCTATGTAACCAGGGAGATCCCTGAAAAAGGTCTTAAACTACTTGAAAAAG
AATGTCATGTGACTGTTAAC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MDKKNELYQQNLLLLKIMWLITVIGVVFLLYRSAPVIMITGFTITCLIVNILLTFLMWKNILTQYIQYFIIVGLSVLAWL
LISTSNSFYSYLILFANLVLIALYTNYWPTLIMGISNLIIVNSLLGGIGRNNLLIIDLYLVLITVLVLTQTHLRIKIQRR
IDEKHQQVIKTEKEKESLLEEIMTTVKELSNFNSSLKENIKVTDRISSEVTKAFTDIAKGIEDQAHSVNEINESARSSNH
NVRALASASNEMLNLSNKTVNATSKGNEQVDLLDTKMQDVDQIINESVDLINRLNEQAQQIGDIVETINNIAKQTNLLAL
NAAIEAARAGEAGQGFAVVADEIRELAEDSHRSTDKIASILQDIKAKTGQVTEQINIGHDAVLSSKNSTEEVKRVFKEID
DNTKNVVEQAQYLEESVRGLEKESQAIVEEISSISSIIEETSASVEEVLAGSEEQTNKVKNIVESFKQLDKLINKLQSLT
KGGS

Sequences:

>Translated_484_residues
MDKKNELYQQNLLLLKIMWLITVIGVVFLLYRSAPVIMITGFTITCLIVNILLTFLMWKNILTQYIQYFIIVGLSVLAWL
LISTSNSFYSYLILFANLVLIALYTNYWPTLIMGISNLIIVNSLLGGIGRNNLLIIDLYLVLITVLVLTQTHLRIKIQRR
IDEKHQQVIKTEKEKESLLEEIMTTVKELSNFNSSLKENIKVTDRISSEVTKAFTDIAKGIEDQAHSVNEINESARSSNH
NVRALASASNEMLNLSNKTVNATSKGNEQVDLLDTKMQDVDQIINESVDLINRLNEQAQQIGDIVETINNIAKQTNLLAL
NAAIEAARAGEAGQGFAVVADEIRELAEDSHRSTDKIASILQDIKAKTGQVTEQINIGHDAVLSSKNSTEEVKRVFKEID
DNTKNVVEQAQYLEESVRGLEKESQAIVEEISSISSIIEETSASVEEVLAGSEEQTNKVKNIVESFKQLDKLINKLQSLT
KGGS
>Mature_484_residues
MDKKNELYQQNLLLLKIMWLITVIGVVFLLYRSAPVIMITGFTITCLIVNILLTFLMWKNILTQYIQYFIIVGLSVLAWL
LISTSNSFYSYLILFANLVLIALYTNYWPTLIMGISNLIIVNSLLGGIGRNNLLIIDLYLVLITVLVLTQTHLRIKIQRR
IDEKHQQVIKTEKEKESLLEEIMTTVKELSNFNSSLKENIKVTDRISSEVTKAFTDIAKGIEDQAHSVNEINESARSSNH
NVRALASASNEMLNLSNKTVNATSKGNEQVDLLDTKMQDVDQIINESVDLINRLNEQAQQIGDIVETINNIAKQTNLLAL
NAAIEAARAGEAGQGFAVVADEIRELAEDSHRSTDKIASILQDIKAKTGQVTEQINIGHDAVLSSKNSTEEVKRVFKEID
DNTKNVVEQAQYLEESVRGLEKESQAIVEEISSISSIIEETSASVEEVLAGSEEQTNKVKNIVESFKQLDKLINKLQSLT
KGGS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=325, Percent_Identity=24.9230769230769, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788194, Length=255, Percent_Identity=28.2352941176471, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI2367378, Length=249, Percent_Identity=28.9156626506024, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787690, Length=359, Percent_Identity=26.4623955431755, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788195, Length=165, Percent_Identity=32.7272727272727, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 54068; Mature: 54068

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKNELYQQNLLLLKIMWLITVIGVVFLLYRSAPVIMITGFTITCLIVNILLTFLMWKN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
ILTQYIQYFIIVGLSVLAWLLISTSNSFYSYLILFANLVLIALYTNYWPTLIMGISNLII
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNSLLGGIGRNNLLIIDLYLVLITVLVLTQTHLRIKIQRRIDEKHQQVIKTEKEKESLLE
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIMTTVKELSNFNSSLKENIKVTDRISSEVTKAFTDIAKGIEDQAHSVNEINESARSSNH
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NVRALASASNEMLNLSNKTVNATSKGNEQVDLLDTKMQDVDQIINESVDLINRLNEQAQQ
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGDIVETINNIAKQTNLLALNAAIEAARAGEAGQGFAVVADEIRELAEDSHRSTDKIASI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
LQDIKAKTGQVTEQINIGHDAVLSSKNSTEEVKRVFKEIDDNTKNVVEQAQYLEESVRGL
HHHHHHHHCCHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EKESQAIVEEISSISSIIEETSASVEEVLAGSEEQTNKVKNIVESFKQLDKLINKLQSLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGGS
CCCC
>Mature Secondary Structure
MDKKNELYQQNLLLLKIMWLITVIGVVFLLYRSAPVIMITGFTITCLIVNILLTFLMWKN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
ILTQYIQYFIIVGLSVLAWLLISTSNSFYSYLILFANLVLIALYTNYWPTLIMGISNLII
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNSLLGGIGRNNLLIIDLYLVLITVLVLTQTHLRIKIQRRIDEKHQQVIKTEKEKESLLE
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIMTTVKELSNFNSSLKENIKVTDRISSEVTKAFTDIAKGIEDQAHSVNEINESARSSNH
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NVRALASASNEMLNLSNKTVNATSKGNEQVDLLDTKMQDVDQIINESVDLINRLNEQAQQ
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGDIVETINNIAKQTNLLALNAAIEAARAGEAGQGFAVVADEIRELAEDSHRSTDKIASI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
LQDIKAKTGQVTEQINIGHDAVLSSKNSTEEVKRVFKEIDDNTKNVVEQAQYLEESVRGL
HHHHHHHHCCHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EKESQAIVEEISSISSIIEETSASVEEVLAGSEEQTNKVKNIVESFKQLDKLINKLQSLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGGS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353924; 9384377 [H]