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The map label for this gene is glgP [H]

Identifier: 220932980

GI number: 220932980

Start: 2336772

End: 2338379

Strand: Reverse

Name: glgP [H]

Synonym: Hore_21480

Alternate gene names: 220932980

Gene position: 2338379-2336772 (Counterclockwise)

Preceding gene: 220932981

Following gene: 220932979

Centisome position: 90.7

GC content: 42.6

Gene sequence:

>1608_bases
ATGGAAGGAAAGAAACCTAAAGTTGCTTATTTTTGTATGGAATTTGGTCTACATGAAGATTTAAGGATTTATGCTGGTGG
GTTGGGAATACTGGCCGGAGATATTCTGAAAGCAGCCAGGGAACTCGATGTACCAATGGTTGGAGTTGGGATACTATGGA
GACAGGGTTATACACGACAGTTAATAGGAGAAGATGGCAGGCCATATGATTCTTATCCGACTAATGACTACATATACGAT
CTGGTAGAGGATACTGGTGTCAAGGTAAAGGTAAAAGTCAGGGATGATGATATTTATTGTAAGGTCTGGAAAGTTGACCG
TTATGATAATGTGCCTCTTTATCTCCTGGATACAAATTTGCCTGAAAACAAAAATAAATGGATTACAGGGCAGCTCTATG
GCTGGTTTGAAGAAGAAAGGATTGCCCAGGAAATTGTCCTGGGGATCGGTGGAGTCCGGGCTTTACGTAAACTGGGGATA
GATGTAGATCTCTACCACTTCAATGATGGTCATCCGGTTCTGGCCGGTACCGAGTTGATTAATGAAAAAATGGCTAAAGG
TATGAGCTTTGATGAGGCCCTGGAAGAAACCCGGAAGGAAGTTATTTTTACCACCCATACCCCTGTTAAAGAGGGGAATG
AGTCCCACGGGCTTGAAGTAATGAAATACATGGGTGCCTTTAATGGTCTAACTCTGGATCAGATGATTAAAATTGGAGAT
AGCCCCTTTAACATGACTGTTGCCGGGCTGCGTTTATCAAGGATAGCAAACGGTGTTTCTGAACTGCACGGGAAAACAGC
ACGGAAAATGTGGTCCTATGTGGATAATAAAGCCCCGATTGTTTCCATAACTAACGGGGTTCACCGTAAATCGTGGGTCG
ATGACAGGATTGTAAAAGCCTATGAAAATGGTGAGGATTTATTAAAACCTCATCAGGAAATTAAGTCAGAACTAATTGAC
TTCGTAGAAGAGAAAACAGGAACCCGTTTAAATCCTGAAGCTCTTCTCATTGGGTTTGCCCGACGGGCAGCACCATATAA
GAGGGGGAACTTAATATTCAGGAAACCTGAGGTTATCCGTCCATACCTGGAAGAAGGTAAAATTCAGATAATATTCTCCG
GTAAGGCTCATCCCCTCGATGATGTCGGTAAAGGTATTATAGCTGATCTGGTGAAGATGAGTGAGAAATACCCCAACAGT
GTTGTTTTCCTTGAAGATTATAATATTGAAATAGGAAGAATGCTTACCAGGGGTGTGGATGTCTGGTTAAATAACCCGAG
ACGTCCTCTGGAAGCCAGTGGTACATCCGGAATGAAGGCAGCCATGAATGGAGCTTTAAATCTAAGTACTCTTGACGGCT
GGTGGCCTGAAGCCTGTGAACATGGGGTAAATGGCTGGCAGCTCGGTGATGGTTATGAAGGAGAAGACCAGGATCAGCAT
GATCTTGATGCCCTATACAATGTTCTATTAAAAGAAGTAGTCCCCACTTATTATGATAATAAGGAAAAATGGGCCCAGAT
GATGAGGGCCAGTATAGAATCAACCTATGATAAATTCTCTGCTCAAAGGATGGTAAGCAGGTATTATGATGAAATGTACC
AAAACTAA

Upstream 100 bases:

>100_bases
AAATTTTTTTAATGAAAAGAAGGAATTTTTTAATTAAAAGAGAATATAAAAAAGTAAAAGAATAATGCAAACGTTATACT
AACTTCGGGGAGGTTTATTA

Downstream 100 bases:

>100_bases
CAAAAGTTCCCTCCCAAAGCCATCAGTATCACCTGATGGCTTTTTTTTAACTTAATTTTAAATTTTTTAGGTGGAGTGTC
TGTGGTTTACGGTTCCTGCT

Product: Alpha-glucan phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MEGKKPKVAYFCMEFGLHEDLRIYAGGLGILAGDILKAARELDVPMVGVGILWRQGYTRQLIGEDGRPYDSYPTNDYIYD
LVEDTGVKVKVKVRDDDIYCKVWKVDRYDNVPLYLLDTNLPENKNKWITGQLYGWFEEERIAQEIVLGIGGVRALRKLGI
DVDLYHFNDGHPVLAGTELINEKMAKGMSFDEALEETRKEVIFTTHTPVKEGNESHGLEVMKYMGAFNGLTLDQMIKIGD
SPFNMTVAGLRLSRIANGVSELHGKTARKMWSYVDNKAPIVSITNGVHRKSWVDDRIVKAYENGEDLLKPHQEIKSELID
FVEEKTGTRLNPEALLIGFARRAAPYKRGNLIFRKPEVIRPYLEEGKIQIIFSGKAHPLDDVGKGIIADLVKMSEKYPNS
VVFLEDYNIEIGRMLTRGVDVWLNNPRRPLEASGTSGMKAAMNGALNLSTLDGWWPEACEHGVNGWQLGDGYEGEDQDQH
DLDALYNVLLKEVVPTYYDNKEKWAQMMRASIESTYDKFSAQRMVSRYYDEMYQN

Sequences:

>Translated_535_residues
MEGKKPKVAYFCMEFGLHEDLRIYAGGLGILAGDILKAARELDVPMVGVGILWRQGYTRQLIGEDGRPYDSYPTNDYIYD
LVEDTGVKVKVKVRDDDIYCKVWKVDRYDNVPLYLLDTNLPENKNKWITGQLYGWFEEERIAQEIVLGIGGVRALRKLGI
DVDLYHFNDGHPVLAGTELINEKMAKGMSFDEALEETRKEVIFTTHTPVKEGNESHGLEVMKYMGAFNGLTLDQMIKIGD
SPFNMTVAGLRLSRIANGVSELHGKTARKMWSYVDNKAPIVSITNGVHRKSWVDDRIVKAYENGEDLLKPHQEIKSELID
FVEEKTGTRLNPEALLIGFARRAAPYKRGNLIFRKPEVIRPYLEEGKIQIIFSGKAHPLDDVGKGIIADLVKMSEKYPNS
VVFLEDYNIEIGRMLTRGVDVWLNNPRRPLEASGTSGMKAAMNGALNLSTLDGWWPEACEHGVNGWQLGDGYEGEDQDQH
DLDALYNVLLKEVVPTYYDNKEKWAQMMRASIESTYDKFSAQRMVSRYYDEMYQN
>Mature_535_residues
MEGKKPKVAYFCMEFGLHEDLRIYAGGLGILAGDILKAARELDVPMVGVGILWRQGYTRQLIGEDGRPYDSYPTNDYIYD
LVEDTGVKVKVKVRDDDIYCKVWKVDRYDNVPLYLLDTNLPENKNKWITGQLYGWFEEERIAQEIVLGIGGVRALRKLGI
DVDLYHFNDGHPVLAGTELINEKMAKGMSFDEALEETRKEVIFTTHTPVKEGNESHGLEVMKYMGAFNGLTLDQMIKIGD
SPFNMTVAGLRLSRIANGVSELHGKTARKMWSYVDNKAPIVSITNGVHRKSWVDDRIVKAYENGEDLLKPHQEIKSELID
FVEEKTGTRLNPEALLIGFARRAAPYKRGNLIFRKPEVIRPYLEEGKIQIIFSGKAHPLDDVGKGIIADLVKMSEKYPNS
VVFLEDYNIEIGRMLTRGVDVWLNNPRRPLEASGTSGMKAAMNGALNLSTLDGWWPEACEHGVNGWQLGDGYEGEDQDQH
DLDALYNVLLKEVVPTYYDNKEKWAQMMRASIESTYDKFSAQRMVSRYYDEMYQN

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties [

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI71037379, Length=444, Percent_Identity=23.4234234234234, Blast_Score=66, Evalue=1e-10,
Organism=Homo sapiens, GI255653002, Length=444, Percent_Identity=23.4234234234234, Blast_Score=66, Evalue=1e-10,
Organism=Escherichia coli, GI48994936, Length=374, Percent_Identity=26.7379679144385, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32566204, Length=498, Percent_Identity=22.289156626506, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17564550, Length=498, Percent_Identity=22.289156626506, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011834
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: =2.4.1.1 [H]

Molecular weight: Translated: 60834; Mature: 60834

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00102 PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGKKPKVAYFCMEFGLHEDLRIYAGGLGILAGDILKAARELDVPMVGVGILWRQGYTRQ
CCCCCCCCEEHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCHH
LIGEDGRPYDSYPTNDYIYDLVEDTGVKVKVKVRDDDIYCKVWKVDRYDNVPLYLLDTNL
HHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCEEEEEEEECCCCCCCEEEEECCC
PENKNKWITGQLYGWFEEERIAQEIVLGIGGVRALRKLGIDVDLYHFNDGHPVLAGTELI
CCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEHHHHHH
NEKMAKGMSFDEALEETRKEVIFTTHTPVKEGNESHGLEVMKYMGAFNGLTLDQMIKIGD
HHHHHCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCC
SPFNMTVAGLRLSRIANGVSELHGKTARKMWSYVDNKAPIVSITNGVHRKSWVDDRIVKA
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHH
YENGEDLLKPHQEIKSELIDFVEEKTGTRLNPEALLIGFARRAAPYKRGNLIFRKPEVIR
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEHHHHCCCCCCCCEEEECCHHHH
PYLEEGKIQIIFSGKAHPLDDVGKGIIADLVKMSEKYPNSVVFLEDYNIEIGRMLTRGVD
HHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCHH
VWLNNPRRPLEASGTSGMKAAMNGALNLSTLDGWWPEACEHGVNGWQLGDGYEGEDQDQH
HEECCCCCCCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHCCCCCEECCCCCCCCCCCHH
DLDALYNVLLKEVVPTYYDNKEKWAQMMRASIESTYDKFSAQRMVSRYYDEMYQN
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEGKKPKVAYFCMEFGLHEDLRIYAGGLGILAGDILKAARELDVPMVGVGILWRQGYTRQ
CCCCCCCCEEHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCHH
LIGEDGRPYDSYPTNDYIYDLVEDTGVKVKVKVRDDDIYCKVWKVDRYDNVPLYLLDTNL
HHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCEEEEEEEECCCCCCCEEEEECCC
PENKNKWITGQLYGWFEEERIAQEIVLGIGGVRALRKLGIDVDLYHFNDGHPVLAGTELI
CCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEHHHHHH
NEKMAKGMSFDEALEETRKEVIFTTHTPVKEGNESHGLEVMKYMGAFNGLTLDQMIKIGD
HHHHHCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCC
SPFNMTVAGLRLSRIANGVSELHGKTARKMWSYVDNKAPIVSITNGVHRKSWVDDRIVKA
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHH
YENGEDLLKPHQEIKSELIDFVEEKTGTRLNPEALLIGFARRAAPYKRGNLIFRKPEVIR
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEHHHHCCCCCCCCEEEECCHHHH
PYLEEGKIQIIFSGKAHPLDDVGKGIIADLVKMSEKYPNSVVFLEDYNIEIGRMLTRGVD
HHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCHH
VWLNNPRRPLEASGTSGMKAAMNGALNLSTLDGWWPEACEHGVNGWQLGDGYEGEDQDQH
HEECCCCCCCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHCCCCCEECCCCCCCCCCCHH
DLDALYNVLLKEVVPTYYDNKEKWAQMMRASIESTYDKFSAQRMVSRYYDEMYQN
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]