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The map label for this gene is spoVC [H]

Identifier: 220932953

GI number: 220932953

Start: 2311224

End: 2311787

Strand: Reverse

Name: spoVC [H]

Synonym: Hore_21210

Alternate gene names: 220932953

Gene position: 2311787-2311224 (Counterclockwise)

Preceding gene: 220932954

Following gene: 220932952

Centisome position: 89.67

GC content: 41.49

Gene sequence:

>564_bases
ATGTATCTGGTGGTTGGTCTGGGAAATCCAGGTGATAAGTATGCTGAAACCCGTCATAATATCGGGTTTCAGGTTATAGA
AAGGCTGGCCAGAAAACATAAAATTAAGGCTAAAAATTACCCCAAATTTGAGGCCCTGTGTGGGAGAGGGATGATAAGAG
GCCAGAAAGTTATGCTGGCACAGCCCCTTACCTATATGAATAACAGTGGTCGGGCTGTGAGAAAAATTATTGATTATTAT
GACTTTTCTCTGGATAATATAATTATAATTTATGATGACCTGGATTTGCCGCCCGGTAAAATCAGGATAAGGAAAAAGGG
AAGTAGTGGGGGCCATAATGGCGTAAAATCTATAATTAATTGTCTTGATACCAGAGAATTCCCCCGGATAAGGATAGGGA
TAGGTCGCCCTCCTGCGGGGGTAAATGTCGTTGATTATGTGCTGGGGTATTTTAGTTCTGAAGACAGTGAAGTAATGTCA
GATGTGCTGGATACTACCGTAGAGGCTGTGGAAACCATTTTAGAAAAAGGGCTGGAACAGGCCATGAATATTTTTAACTC
ATAG

Upstream 100 bases:

>100_bases
GTGATGAAGAGGAGCCTGAAGAATAAAATAGCATAAAAGTACTTAAAAGCGTAATCCGGGTGTCCGGATTGCGCTTTAAG
TATAACCTGGAGGGGTAACA

Downstream 100 bases:

>100_bases
GTCCGTGCTTTATGGCGGGGGCCCTTTTGGCATTTATTATATATTTTCAGGGAGATGTTTTATGAAATTATCAGATCTGC
TATTATCAAGCGAGAAGACG

Product: Aminoacyl-tRNA hydrolase

Products: NA

Alternate protein names: PTH; Stage V sporulation protein C [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MYLVVGLGNPGDKYAETRHNIGFQVIERLARKHKIKAKNYPKFEALCGRGMIRGQKVMLAQPLTYMNNSGRAVRKIIDYY
DFSLDNIIIIYDDLDLPPGKIRIRKKGSSGGHNGVKSIINCLDTREFPRIRIGIGRPPAGVNVVDYVLGYFSSEDSEVMS
DVLDTTVEAVETILEKGLEQAMNIFNS

Sequences:

>Translated_187_residues
MYLVVGLGNPGDKYAETRHNIGFQVIERLARKHKIKAKNYPKFEALCGRGMIRGQKVMLAQPLTYMNNSGRAVRKIIDYY
DFSLDNIIIIYDDLDLPPGKIRIRKKGSSGGHNGVKSIINCLDTREFPRIRIGIGRPPAGVNVVDYVLGYFSSEDSEVMS
DVLDTTVEAVETILEKGLEQAMNIFNS
>Mature_187_residues
MYLVVGLGNPGDKYAETRHNIGFQVIERLARKHKIKAKNYPKFEALCGRGMIRGQKVMLAQPLTYMNNSGRAVRKIIDYY
DFSLDNIIIIYDDLDLPPGKIRIRKKGSSGGHNGVKSIINCLDTREFPRIRIGIGRPPAGVNVVDYVLGYFSSEDSEVMS
DVLDTTVEAVETILEKGLEQAMNIFNS

Specific function: The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis [H]

COG id: COG0193

COG function: function code J; Peptidyl-tRNA hydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTH family [H]

Homologues:

Organism=Homo sapiens, GI50897284, Length=172, Percent_Identity=33.1395348837209, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1787455, Length=182, Percent_Identity=37.3626373626374, Blast_Score=112, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321983, Length=166, Percent_Identity=30.1204819277108, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001328
- InterPro:   IPR018171 [H]

Pfam domain/function: PF01195 Pept_tRNA_hydro [H]

EC number: =3.1.1.29 [H]

Molecular weight: Translated: 20955; Mature: 20955

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS01195 PEPT_TRNA_HYDROL_1 ; PS01196 PEPT_TRNA_HYDROL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLVVGLGNPGDKYAETRHNIGFQVIERLARKHKIKAKNYPKFEALCGRGMIRGQKVMLA
CEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHEE
QPLTYMNNSGRAVRKIIDYYDFSLDNIIIIYDDLDLPPGKIRIRKKGSSGGHNGVKSIIN
CCHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHH
CLDTREFPRIRIGIGRPPAGVNVVDYVLGYFSSEDSEVMSDVLDTTVEAVETILEKGLEQ
HHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AMNIFNS
HHHHHCC
>Mature Secondary Structure
MYLVVGLGNPGDKYAETRHNIGFQVIERLARKHKIKAKNYPKFEALCGRGMIRGQKVMLA
CEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHEE
QPLTYMNNSGRAVRKIIDYYDFSLDNIIIIYDDLDLPPGKIRIRKKGSSGGHNGVKSIIN
CCHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHH
CLDTREFPRIRIGIGRPPAGVNVVDYVLGYFSSEDSEVMSDVLDTTVEAVETILEKGLEQ
HHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AMNIFNS
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]