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The map label for this gene is dnaX [H]

Identifier: 220932911

GI number: 220932911

Start: 2246334

End: 2248100

Strand: Reverse

Name: dnaX [H]

Synonym: Hore_20790

Alternate gene names: 220932911

Gene position: 2248100-2246334 (Counterclockwise)

Preceding gene: 220932912

Following gene: 220932910

Centisome position: 87.2

GC content: 40.8

Gene sequence:

>1767_bases
ATGGGATTTTTATCTTTATATAGAAAGTACCGTCCTCAAAACTTTAATGACCTGGTCGGCCAGCACCATGTTGTCCGGAC
TTTAAAAAACGCCCTGGAAAGTGGTAGAATAGCCCATGCCTATCTCTTTGCCGGGCCCAGGGGGACAGGGAAAACATCAA
CTGCCAAGGTATTTGCCATGGCTTTAAATTGTATTCATGGTCCTACTACGGAACCATGTGGTCAATGTGAGAACTGCCGT
AAGATCCAGAAAGGTCAGTCCATTGATGTTATTGAAATTGATGCTGCATCAAACCGTGGGATTGATGAAATAAGGGAATT
AAGGGAAAAGGTTAAATTTTACCCCAATGAGGGGGAATATAAAGTATATATAATAGATGAAGTTCATATGTTAACTAAAG
GGGCCTTTAATGCTTTATTAAAAACCCTGGAGGAACCACCGGAAAAGGTGGTATTTATCCTGGCTACCACTGAACCCCAT
CAGGTTATTAATACTATTCTATCACGCTGTCAGCGCTTTGATTTCTCCCTGCTCCCGGTCAGGGAAATTCAGGAGAGGCT
CCGCTATATCTGTGAAAAAGAGGAGGTTGAATTTGAGGAAGAGGCTCTAAATATACTGGCCCGGTCAGCCAATGGGGGCC
TCAGGGATGCTATAAGTCTCCTGGATCAGGCGATATCTTACACAGGTAATAACCTCAACCCCATTGATGTGCAGGGTATG
CTCGGCAAGGTAAGCCGGGAGGTTTTAAGCCAGTTTATCAAATATGTTCTCAACGGGAATTCGGTTGAGGCTTTAAAACT
GGTAAATAGAATAATCAGTCGGGGAAATAATGTAGGGCGTCTTATAGGTGATTTGATTGAATACGGGAGGCAGCTCCTTC
TTGTAAAAGAATGCGGCCCTGATTCCAGGATTATAGAATATCCTGATGAGGTTTTAGAGAAAATATCAGGTGAGGCCAGA
GCCATAAAGACCAGCAGATTGATTGAAATAATAGATCAGCTTACAGTAATGGAGCGTGATATTAAATATTCTGATGAGCC
CCGGCTAATCCTTGAAGTCGGTATTATAAAGATGGCTAACCCTGAGGCCGGAGGTTCAATTATAGACCTGGAAAAGAGAA
TTGCCAGGCTGGAAAATATAATATCAGGAAAAATAACCGCTAATGATGGGGATAGAATAACATCAACTTTTAATACTGTT
TCTGGAAGCGATAAAGTTATGACCGGACAGGGTGTGAAAAAGAAGAATAAAAAAGGTAGTATTAAAGATAATAAAGCAGA
CAAAAACCGGGTTAAAAGCGATAACACTCCTGAACATGAGACCGGCATCAGAACTGATATGGGTGGTGGACAGGGAGTTG
AAGATGCCTCAGGAGGCGAATTAACCCTTGATAAATTCAGAAAAGGATGGCCTGTTGTCTTAAAACAGATTAAAGAAAAA
AATATCAAGGCCCAGGCTTTTTTAATAGAATCCCGACCTGCTGCCTTTGATGGTGAGGTTCTGGTTATTGAATTTCCTGA
AGATAAGGCTTTTCATAAAAAAGGAGCGGAAAAGGAGAAAAAGTTGATTGAAGATGTGGTTAGTAAGATAGCCGGGACAA
GATGTCAGGTCAGATTCCGGCTTGCAGGAGAAAAAGAAAAGGGGTATAATAATACTGCTGTTAAAAAAAAAGAAAAAAAC
AAAAAAGATGATGACCTGGTAAACAGGGTTATGGAACTTTTTGATGGAGAGATTATTAAGGTCAATCATGAGGTTATAGA
AAATTAA

Upstream 100 bases:

>100_bases
TTATTTATAGTTAAATATTTGAAGGAAAACAGAAAGATTTCTAGAATAAATTTTTGAAGGGTATGATAAAAGCGGAAGTA
ACTTGTGGGAGTGAACCTGT

Downstream 100 bases:

>100_bases
AGGAGGTTTTTTAAGATGAATATGAATAAATTAATGAAGCAGGCCCAGAAAATGCAGGCTAAAATGGCTAAAATGCAGGA
GGAACTTGAAGAAAAAACCG

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MGFLSLYRKYRPQNFNDLVGQHHVVRTLKNALESGRIAHAYLFAGPRGTGKTSTAKVFAMALNCIHGPTTEPCGQCENCR
KIQKGQSIDVIEIDAASNRGIDEIRELREKVKFYPNEGEYKVYIIDEVHMLTKGAFNALLKTLEEPPEKVVFILATTEPH
QVINTILSRCQRFDFSLLPVREIQERLRYICEKEEVEFEEEALNILARSANGGLRDAISLLDQAISYTGNNLNPIDVQGM
LGKVSREVLSQFIKYVLNGNSVEALKLVNRIISRGNNVGRLIGDLIEYGRQLLLVKECGPDSRIIEYPDEVLEKISGEAR
AIKTSRLIEIIDQLTVMERDIKYSDEPRLILEVGIIKMANPEAGGSIIDLEKRIARLENIISGKITANDGDRITSTFNTV
SGSDKVMTGQGVKKKNKKGSIKDNKADKNRVKSDNTPEHETGIRTDMGGGQGVEDASGGELTLDKFRKGWPVVLKQIKEK
NIKAQAFLIESRPAAFDGEVLVIEFPEDKAFHKKGAEKEKKLIEDVVSKIAGTRCQVRFRLAGEKEKGYNNTAVKKKEKN
KKDDDLVNRVMELFDGEIIKVNHEVIEN

Sequences:

>Translated_588_residues
MGFLSLYRKYRPQNFNDLVGQHHVVRTLKNALESGRIAHAYLFAGPRGTGKTSTAKVFAMALNCIHGPTTEPCGQCENCR
KIQKGQSIDVIEIDAASNRGIDEIRELREKVKFYPNEGEYKVYIIDEVHMLTKGAFNALLKTLEEPPEKVVFILATTEPH
QVINTILSRCQRFDFSLLPVREIQERLRYICEKEEVEFEEEALNILARSANGGLRDAISLLDQAISYTGNNLNPIDVQGM
LGKVSREVLSQFIKYVLNGNSVEALKLVNRIISRGNNVGRLIGDLIEYGRQLLLVKECGPDSRIIEYPDEVLEKISGEAR
AIKTSRLIEIIDQLTVMERDIKYSDEPRLILEVGIIKMANPEAGGSIIDLEKRIARLENIISGKITANDGDRITSTFNTV
SGSDKVMTGQGVKKKNKKGSIKDNKADKNRVKSDNTPEHETGIRTDMGGGQGVEDASGGELTLDKFRKGWPVVLKQIKEK
NIKAQAFLIESRPAAFDGEVLVIEFPEDKAFHKKGAEKEKKLIEDVVSKIAGTRCQVRFRLAGEKEKGYNNTAVKKKEKN
KKDDDLVNRVMELFDGEIIKVNHEVIEN
>Mature_587_residues
GFLSLYRKYRPQNFNDLVGQHHVVRTLKNALESGRIAHAYLFAGPRGTGKTSTAKVFAMALNCIHGPTTEPCGQCENCRK
IQKGQSIDVIEIDAASNRGIDEIRELREKVKFYPNEGEYKVYIIDEVHMLTKGAFNALLKTLEEPPEKVVFILATTEPHQ
VINTILSRCQRFDFSLLPVREIQERLRYICEKEEVEFEEEALNILARSANGGLRDAISLLDQAISYTGNNLNPIDVQGML
GKVSREVLSQFIKYVLNGNSVEALKLVNRIISRGNNVGRLIGDLIEYGRQLLLVKECGPDSRIIEYPDEVLEKISGEARA
IKTSRLIEIIDQLTVMERDIKYSDEPRLILEVGIIKMANPEAGGSIIDLEKRIARLENIISGKITANDGDRITSTFNTVS
GSDKVMTGQGVKKKNKKGSIKDNKADKNRVKSDNTPEHETGIRTDMGGGQGVEDASGGELTLDKFRKGWPVVLKQIKEKN
IKAQAFLIESRPAAFDGEVLVIEFPEDKAFHKKGAEKEKKLIEDVVSKIAGTRCQVRFRLAGEKEKGYNNTAVKKKEKNK
KDDDLVNRVMELFDGEIIKVNHEVIEN

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31563534, Length=289, Percent_Identity=27.681660899654, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI4506491, Length=290, Percent_Identity=29.3103448275862, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI31881687, Length=290, Percent_Identity=29.3103448275862, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI6677723, Length=269, Percent_Identity=27.1375464684015, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI194306571, Length=267, Percent_Identity=26.9662921348315, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI194306567, Length=267, Percent_Identity=26.9662921348315, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1786676, Length=361, Percent_Identity=39.8891966759003, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1787119, Length=232, Percent_Identity=28.448275862069, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787341, Length=271, Percent_Identity=29.1512915129151, Blast_Score=73, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71986063, Length=325, Percent_Identity=27.6923076923077, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17554730, Length=232, Percent_Identity=30.6034482758621, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17541988, Length=327, Percent_Identity=25.0764525993884, Blast_Score=92, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6322528, Length=298, Percent_Identity=29.8657718120805, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324039, Length=233, Percent_Identity=30.0429184549356, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6324478, Length=230, Percent_Identity=26.9565217391304, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI18859927, Length=295, Percent_Identity=28.8135593220339, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19921076, Length=259, Percent_Identity=28.957528957529, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17647857, Length=297, Percent_Identity=24.2424242424242, Blast_Score=86, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 65910; Mature: 65778

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFLSLYRKYRPQNFNDLVGQHHVVRTLKNALESGRIAHAYLFAGPRGTGKTSTAKVFAM
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHH
ALNCIHGPTTEPCGQCENCRKIQKGQSIDVIEIDAASNRGIDEIRELREKVKFYPNEGEY
HHHHHCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCE
KVYIIDEVHMLTKGAFNALLKTLEEPPEKVVFILATTEPHQVINTILSRCQRFDFSLLPV
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCH
REIQERLRYICEKEEVEFEEEALNILARSANGGLRDAISLLDQAISYTGNNLNPIDVQGM
HHHHHHHHHHHCHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
LGKVSREVLSQFIKYVLNGNSVEALKLVNRIISRGNNVGRLIGDLIEYGRQLLLVKECGP
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCC
DSRIIEYPDEVLEKISGEARAIKTSRLIEIIDQLTVMERDIKYSDEPRLILEVGIIKMAN
CCCEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECC
PEAGGSIIDLEKRIARLENIISGKITANDGDRITSTFNTVSGSDKVMTGQGVKKKNKKGS
CCCCCCEEHHHHHHHHHHHHHCCCEECCCCCCHHHHHHCCCCCCCEEECCCCCCCCCCCC
IKDNKADKNRVKSDNTPEHETGIRTDMGGGQGVEDASGGELTLDKFRKGWPVVLKQIKEK
CCCCCCHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCEEHHHHCCCHHHHHHHHHHC
NIKAQAFLIESRPAAFDGEVLVIEFPEDKAFHKKGAEKEKKLIEDVVSKIAGTRCQVRFR
CCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEE
LAGEKEKGYNNTAVKKKEKNKKDDDLVNRVMELFDGEIIKVNHEVIEN
ECCCCCCCCCCCHHCCHHCCCCHHHHHHHHHHHHCCCEEEECHHHHCC
>Mature Secondary Structure 
GFLSLYRKYRPQNFNDLVGQHHVVRTLKNALESGRIAHAYLFAGPRGTGKTSTAKVFAM
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHH
ALNCIHGPTTEPCGQCENCRKIQKGQSIDVIEIDAASNRGIDEIRELREKVKFYPNEGEY
HHHHHCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCE
KVYIIDEVHMLTKGAFNALLKTLEEPPEKVVFILATTEPHQVINTILSRCQRFDFSLLPV
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCH
REIQERLRYICEKEEVEFEEEALNILARSANGGLRDAISLLDQAISYTGNNLNPIDVQGM
HHHHHHHHHHHCHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
LGKVSREVLSQFIKYVLNGNSVEALKLVNRIISRGNNVGRLIGDLIEYGRQLLLVKECGP
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCC
DSRIIEYPDEVLEKISGEARAIKTSRLIEIIDQLTVMERDIKYSDEPRLILEVGIIKMAN
CCCEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECC
PEAGGSIIDLEKRIARLENIISGKITANDGDRITSTFNTVSGSDKVMTGQGVKKKNKKGS
CCCCCCEEHHHHHHHHHHHHHCCCEECCCCCCHHHHHHCCCCCCCEEECCCCCCCCCCCC
IKDNKADKNRVKSDNTPEHETGIRTDMGGGQGVEDASGGELTLDKFRKGWPVVLKQIKEK
CCCCCCHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCEEHHHHCCCHHHHHHHHHHC
NIKAQAFLIESRPAAFDGEVLVIEFPEDKAFHKKGAEKEKKLIEDVVSKIAGTRCQVRFR
CCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEE
LAGEKEKGYNNTAVKKKEKNKKDDDLVNRVMELFDGEIIKVNHEVIEN
ECCCCCCCCCCCHHCCHHCCCCHHHHHHHHHHHHCCCEEEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]