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The map label for this gene is trxB [H]

Identifier: 220932873

GI number: 220932873

Start: 2198992

End: 2199927

Strand: Reverse

Name: trxB [H]

Synonym: Hore_20410

Alternate gene names: 220932873

Gene position: 2199927-2198992 (Counterclockwise)

Preceding gene: 220932874

Following gene: 220932871

Centisome position: 85.33

GC content: 40.49

Gene sequence:

>936_bases
ATGGCAGGAAATAATAAAGAAAAAATGATTATAATAGGTGGAGGACCAGCTGGTTTGACAGCCGCCATCTATGCGGCCAG
GGCAGGTTTAAATCCGATGGTGATTGTTGGTCCTGAGCCCGGAGGTCAGATAACAACTACTTCTGAAATTGAAAATTACC
CGGGATTCCCTGAGGGAATTACTGGTTTTGATTTAATGCAAAAGGTTATTGAACAGGCTCAAAAGTTTGATGTTCGCTTA
CAGTATGAAGTGGTAGAAAACGTTGATTTTAATAACAGTCCTTATAATATAAAAACTGATGGGGGAGAATATCAGGCAGA
TTCTATAATAATAGCTACCGGTGCTTCCCCCCGGAAACTCGGTCTTGAGAAGGAAGAGGACTTTATCGGTAAAGGTATTT
CATACTGTGCCACCTGTGATGGGGCCTTTTTTAAAGATCAGGAAGTGGCTGTTGTTGGTGGTGGAGATGTTGCCCTTGAA
GAGGCTAATTACCTGACTAATTTCTGCTCTAAAGTTTATTTAATACACCGCAGGGATCAGTTCAGGGGTACTAAAATTCT
TGGTGACAGGGTTAAAAATAATTCTAAAGTTGAAATATTATGGGATACAGAAGTAAGGGAATTACTTGGAGGCAATAAAG
TTGAAGGCCTGCTGGTAGAAAATAATAAGACCGGAGAAGAAACCAGACTTGAAAATGTGAAAGCTTTATTTATTGCTGTA
GGTTATAAACCAAATACAGATCTGTTTAAAGGGCAGCTGGAAGTAGATGACAGGGGTTACATTATAACCAATGACAGATT
AATGACCAGTAAGGAAGGAATTTTTGCAGCAGGTGATGTTCAGGACCCCCATTACCGTCAGGTTGTTACTTCTGCAGCCA
GTGGTGCCATAGCCGCTATGGAGGCAGGGAAATATTTAGAAACCATTGAAGATTAA

Upstream 100 bases:

>100_bases
AGATGTAGTCAGGTTTACAGCATCAATATCAAAAAAATATTATTATTTTATCTGTACAGAGGATATATTAATAAGCAGGA
ATATTAAGGGGGTCATAGAA

Downstream 100 bases:

>100_bases
TTGTTGGAAAATAAGCTGGCTTTAAATTCTTTAACCAGGGGTACTGAAACCCCCAGTTTTTTGGCGATTTCTTCATCATT
CATTCCCATAGACCAGGCTA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MAGNNKEKMIIIGGGPAGLTAAIYAARAGLNPMVIVGPEPGGQITTTSEIENYPGFPEGITGFDLMQKVIEQAQKFDVRL
QYEVVENVDFNNSPYNIKTDGGEYQADSIIIATGASPRKLGLEKEEDFIGKGISYCATCDGAFFKDQEVAVVGGGDVALE
EANYLTNFCSKVYLIHRRDQFRGTKILGDRVKNNSKVEILWDTEVRELLGGNKVEGLLVENNKTGEETRLENVKALFIAV
GYKPNTDLFKGQLEVDDRGYIITNDRLMTSKEGIFAAGDVQDPHYRQVVTSAASGAIAAMEAGKYLETIED

Sequences:

>Translated_311_residues
MAGNNKEKMIIIGGGPAGLTAAIYAARAGLNPMVIVGPEPGGQITTTSEIENYPGFPEGITGFDLMQKVIEQAQKFDVRL
QYEVVENVDFNNSPYNIKTDGGEYQADSIIIATGASPRKLGLEKEEDFIGKGISYCATCDGAFFKDQEVAVVGGGDVALE
EANYLTNFCSKVYLIHRRDQFRGTKILGDRVKNNSKVEILWDTEVRELLGGNKVEGLLVENNKTGEETRLENVKALFIAV
GYKPNTDLFKGQLEVDDRGYIITNDRLMTSKEGIFAAGDVQDPHYRQVVTSAASGAIAAMEAGKYLETIED
>Mature_310_residues
AGNNKEKMIIIGGGPAGLTAAIYAARAGLNPMVIVGPEPGGQITTTSEIENYPGFPEGITGFDLMQKVIEQAQKFDVRLQ
YEVVENVDFNNSPYNIKTDGGEYQADSIIIATGASPRKLGLEKEEDFIGKGISYCATCDGAFFKDQEVAVVGGGDVALEE
ANYLTNFCSKVYLIHRRDQFRGTKILGDRVKNNSKVEILWDTEVRELLGGNKVEGLLVENNKTGEETRLENVKALFIAVG
YKPNTDLFKGQLEVDDRGYIITNDRLMTSKEGIFAAGDVQDPHYRQVVTSAASGAIAAMEAGKYLETIED

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI50301238, Length=207, Percent_Identity=31.4009661835749, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1787114, Length=322, Percent_Identity=46.8944099378882, Blast_Score=290, Evalue=7e-80,
Organism=Escherichia coli, GI87081763, Length=301, Percent_Identity=31.8936877076412, Blast_Score=138, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=316, Percent_Identity=46.2025316455696, Blast_Score=269, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=44.794952681388, Blast_Score=262, Evalue=6e-71,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33882; Mature: 33750

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNNKEKMIIIGGGPAGLTAAIYAARAGLNPMVIVGPEPGGQITTTSEIENYPGFPEGI
CCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEEHHHHHCCCCCCCCC
TGFDLMQKVIEQAQKFDVRLQYEVVENVDFNNSPYNIKTDGGEYQADSIIIATGASPRKL
CHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEECCCCEEECEEEEEECCCCHHC
GLEKEEDFIGKGISYCATCDGAFFKDQEVAVVGGGDVALEEANYLTNFCSKVYLIHRRDQ
CCCCCHHHHHCCCCEEEECCCCEECCCCEEEEECCCEEEHHHHHHHHHHHHEEEEEECCC
FRGTKILGDRVKNNSKVEILWDTEVRELLGGNKVEGLLVENNKTGEETRLENVKALFIAV
CCCCEEEHHHCCCCCEEEEEECCHHHHHHCCCCEEEEEEECCCCCCHHHHHCEEEEEEEE
GYKPNTDLFKGQLEVDDRGYIITNDRLMTSKEGIFAAGDVQDPHYRQVVTSAASGAIAAM
CCCCCCCCEEEEEEECCCCEEEECCEEEECCCCEEEECCCCCCHHHHHHHHHCCCCEEEH
EAGKYLETIED
HCCHHHHHHCC
>Mature Secondary Structure 
AGNNKEKMIIIGGGPAGLTAAIYAARAGLNPMVIVGPEPGGQITTTSEIENYPGFPEGI
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEEHHHHHCCCCCCCCC
TGFDLMQKVIEQAQKFDVRLQYEVVENVDFNNSPYNIKTDGGEYQADSIIIATGASPRKL
CHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEECCCCEEECEEEEEECCCCHHC
GLEKEEDFIGKGISYCATCDGAFFKDQEVAVVGGGDVALEEANYLTNFCSKVYLIHRRDQ
CCCCCHHHHHCCCCEEEECCCCEECCCCEEEEECCCEEEHHHHHHHHHHHHEEEEEECCC
FRGTKILGDRVKNNSKVEILWDTEVRELLGGNKVEGLLVENNKTGEETRLENVKALFIAV
CCCCEEEHHHCCCCCEEEEEECCHHHHHHCCCCEEEEEEECCCCCCHHHHHCEEEEEEEE
GYKPNTDLFKGQLEVDDRGYIITNDRLMTSKEGIFAAGDVQDPHYRQVVTSAASGAIAAM
CCCCCCCCEEEEEEECCCCEEEECCEEEECCCCEEEECCCCCCHHHHHHHHHCCCCEEEH
EAGKYLETIED
HCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]