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The map label for this gene is yugJ [H]

Identifier: 220932863

GI number: 220932863

Start: 2191498

End: 2192661

Strand: Reverse

Name: yugJ [H]

Synonym: Hore_20310

Alternate gene names: 220932863

Gene position: 2192661-2191498 (Counterclockwise)

Preceding gene: 220932864

Following gene: 220932862

Centisome position: 85.05

GC content: 43.81

Gene sequence:

>1164_bases
ATGAATAACTTTACTTTTCATAACCCTACAGAGCTCTTATTTGGTAAAGGCATGATTAAACAACTGGGAGACAGGGTAAA
AAAATTTGGAAATTCTGTTCTCCTGGTTACAGGGGGAGGTAGTGTTAAGAGGATAGGGCTCTATGATGAGGTTATTGGCA
TTTTAAATGAAAATGGGATAGACATCCATGAAGTAAGTGGGGTCAAGCCCAATCCACGAATAGACAAGGTTCGCGAAGGT
GTTAAAATCTGTCGTGAAAATAATGTTGACCTTGTACTCGGGGTCGGTGGTGGGAGTACCATTGACACTGCTAAATCAAT
TGCCGCCGGTGTTAAGTTCGATGGAGACCCATGGGAGATGTTTACTATGGACGGAGAGCCTGATAAGGCTATTCCGGTTG
GGGCTGTTTTAACCCTGGCAGCGACAGGTACTGAGATGAACGGAAACGCTGTTATTTCTAACCTTGAAACTAATGAGAAA
CTTGCTATACATACCCCGGCAGTAAACCCCAGATTTTCCATACTTGACCCCGTTTATACCTGTACAGTTCCTGAGGAACA
TACAGTTTACGGTATTGTCGATATTGCGGCTCATGTCTATGAACAGTATTTTAGCCATACTCCGGGTACCCCTGTTCAGG
ACAGGTGGGCTGAGAGTATTTTAATAACTCTGAGGGAGGAAAGCAAGAAGGTTCTCGATAATCCTGAAGATTATGAGGCC
CGGGCCAACATTATGTTATGTGGTACTATGGCTTTGAATGGGTTAATTGCTATGGGGAAGGAGACCGACTGGGCTTCTCA
TGCTATTGAACATGAGCTCAGCGCTTTTTATGATATCCCCCACGGTGGAGGATTAGCTATAATCTTTCCCAACTGGATGA
AGTATGTAATGGATGAAGGGCTCGATAAATTTGTCCAGTATGCGGTCAGGGTTTTCGGGGTCTCAACTGATGATAAAACA
GACCGGGAAGTTGCCCTGGAGGGTATTGAGAAAACCCGGCAGTGGTTTAACGAGATGGGAGCCCCTTCCCGGCTTGCTGA
TTATAATATAGGTGAAGAAAAACTTGAAATAATGGCCGAGAGTGCTGTTTCTAATAAAGAACTGGGTGGGTATAAAAAAC
TCACTAAAGATGATGTCTACCAGATTCTAAAAATGAGTCTCTAG

Upstream 100 bases:

>100_bases
TATAAAAAAGCAGTAGTTATTAAAGCCAGGCCCGAAAAACGTTGACAGGGAGAATTAAATTTTATAGAATTAGAATAATA
TAGTAAAGAGGTGAAGTGAT

Downstream 100 bases:

>100_bases
AAAAATGTATAGTGAGAAAGAGGTATAGAAAGCATCCATTAACATGTTTGCATAATGTTGTAGACAACTGAATTGTGAAG
GAAAGGAGATGAATATCATG

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNNFTFHNPTELLFGKGMIKQLGDRVKKFGNSVLLVTGGGSVKRIGLYDEVIGILNENGIDIHEVSGVKPNPRIDKVREG
VKICRENNVDLVLGVGGGSTIDTAKSIAAGVKFDGDPWEMFTMDGEPDKAIPVGAVLTLAATGTEMNGNAVISNLETNEK
LAIHTPAVNPRFSILDPVYTCTVPEEHTVYGIVDIAAHVYEQYFSHTPGTPVQDRWAESILITLREESKKVLDNPEDYEA
RANIMLCGTMALNGLIAMGKETDWASHAIEHELSAFYDIPHGGGLAIIFPNWMKYVMDEGLDKFVQYAVRVFGVSTDDKT
DREVALEGIEKTRQWFNEMGAPSRLADYNIGEEKLEIMAESAVSNKELGGYKKLTKDDVYQILKMSL

Sequences:

>Translated_387_residues
MNNFTFHNPTELLFGKGMIKQLGDRVKKFGNSVLLVTGGGSVKRIGLYDEVIGILNENGIDIHEVSGVKPNPRIDKVREG
VKICRENNVDLVLGVGGGSTIDTAKSIAAGVKFDGDPWEMFTMDGEPDKAIPVGAVLTLAATGTEMNGNAVISNLETNEK
LAIHTPAVNPRFSILDPVYTCTVPEEHTVYGIVDIAAHVYEQYFSHTPGTPVQDRWAESILITLREESKKVLDNPEDYEA
RANIMLCGTMALNGLIAMGKETDWASHAIEHELSAFYDIPHGGGLAIIFPNWMKYVMDEGLDKFVQYAVRVFGVSTDDKT
DREVALEGIEKTRQWFNEMGAPSRLADYNIGEEKLEIMAESAVSNKELGGYKKLTKDDVYQILKMSL
>Mature_387_residues
MNNFTFHNPTELLFGKGMIKQLGDRVKKFGNSVLLVTGGGSVKRIGLYDEVIGILNENGIDIHEVSGVKPNPRIDKVREG
VKICRENNVDLVLGVGGGSTIDTAKSIAAGVKFDGDPWEMFTMDGEPDKAIPVGAVLTLAATGTEMNGNAVISNLETNEK
LAIHTPAVNPRFSILDPVYTCTVPEEHTVYGIVDIAAHVYEQYFSHTPGTPVQDRWAESILITLREESKKVLDNPEDYEA
RANIMLCGTMALNGLIAMGKETDWASHAIEHELSAFYDIPHGGGLAIIFPNWMKYVMDEGLDKFVQYAVRVFGVSTDDKT
DREVALEGIEKTRQWFNEMGAPSRLADYNIGEEKLEIMAESAVSNKELGGYKKLTKDDVYQILKMSL

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=397, Percent_Identity=20.4030226700252, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1789386, Length=353, Percent_Identity=42.7762039660057, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI48994951, Length=393, Percent_Identity=26.2086513994911, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1789163, Length=373, Percent_Identity=24.9329758713137, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082107, Length=343, Percent_Identity=25.0728862973761, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787493, Length=382, Percent_Identity=23.8219895287958, Blast_Score=78, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17537053, Length=392, Percent_Identity=19.8979591836735, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321181, Length=383, Percent_Identity=28.9817232375979, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24657991, Length=426, Percent_Identity=18.7793427230047, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42604; Mature: 42604

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFTFHNPTELLFGKGMIKQLGDRVKKFGNSVLLVTGGGSVKRIGLYDEVIGILNENGI
CCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCEEEEEECCCCEEEECHHHHHHHHHCCCCC
DIHEVSGVKPNPRIDKVREGVKICRENNVDLVLGVGGGSTIDTAKSIAAGVKFDGDPWEM
CEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEE
FTMDGEPDKAIPVGAVLTLAATGTEMNGNAVISNLETNEKLAIHTPAVNPRFSILDPVYT
EEECCCCCCCCCHHHEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCCCCEECCCEEE
CTVPEEHTVYGIVDIAAHVYEQYFSHTPGTPVQDRWAESILITLREESKKVLDNPEDYEA
ECCCCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEEEHHHHHHHCCCCCCCHH
RANIMLCGTMALNGLIAMGKETDWASHAIEHELSAFYDIPHGGGLAIIFPNWMKYVMDEG
HCCEEEEEHHHHCCEEEECCCCCHHHHHHHHHHHHHEECCCCCCEEEECHHHHHHHHHHH
LDKFVQYAVRVFGVSTDDKTDREVALEGIEKTRQWFNEMGAPSRLADYNIGEEKLEIMAE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHH
SAVSNKELGGYKKLTKDDVYQILKMSL
HHCCCCCCCCHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MNNFTFHNPTELLFGKGMIKQLGDRVKKFGNSVLLVTGGGSVKRIGLYDEVIGILNENGI
CCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCEEEEEECCCCEEEECHHHHHHHHHCCCCC
DIHEVSGVKPNPRIDKVREGVKICRENNVDLVLGVGGGSTIDTAKSIAAGVKFDGDPWEM
CEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEE
FTMDGEPDKAIPVGAVLTLAATGTEMNGNAVISNLETNEKLAIHTPAVNPRFSILDPVYT
EEECCCCCCCCCHHHEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCCCCEECCCEEE
CTVPEEHTVYGIVDIAAHVYEQYFSHTPGTPVQDRWAESILITLREESKKVLDNPEDYEA
ECCCCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEEEHHHHHHHCCCCCCCHH
RANIMLCGTMALNGLIAMGKETDWASHAIEHELSAFYDIPHGGGLAIIFPNWMKYVMDEG
HCCEEEEEHHHHCCEEEECCCCCHHHHHHHHHHHHHEECCCCCCEEEECHHHHHHHHHHH
LDKFVQYAVRVFGVSTDDKTDREVALEGIEKTRQWFNEMGAPSRLADYNIGEEKLEIMAE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHH
SAVSNKELGGYKKLTKDDVYQILKMSL
HHCCCCCCCCHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]