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The map label for this gene is yesM [H]

Identifier: 220932819

GI number: 220932819

Start: 2139087

End: 2140874

Strand: Reverse

Name: yesM [H]

Synonym: Hore_19850

Alternate gene names: 220932819

Gene position: 2140874-2139087 (Counterclockwise)

Preceding gene: 220932820

Following gene: 220932818

Centisome position: 83.04

GC content: 37.86

Gene sequence:

>1788_bases
ATGAAGGCCTTAAAAAAAATCATGCAAACATTATCTTCGTTATTTCAGATACAGACCCTCAGAACAAAGCTGGTCTTTTC
TTTTCTCCTATTTGGCCTCGTTCCTTTTCTTATATTTGCCTTTTTTTCTTATAATAAATACCTCGGGGCTCTTCAGGAAA
GGATAACAACCTACTCCGAAGGTGTGGTCTCCAGGATGCAGAAGGATCTGGATGAATACCTCCAGGATGTTAATTCACTG
TTAAATATGAAGGATGACTATTATATTAACCAGTTTATTAAACTTAAGAGGGCAGGAGATTTTGAAGGTAACAGGAAATA
TACCTTCCGGTTGTGGGAAGACTTTAGTACCCTGACAAGGATAAAAGAAGGGATTGAAGATGTTGCCCTGACCTTTGATG
ACGGGAAGAGGTTCAGTACCTACGGGTTGTATTATGCAATCCCTGAGACAATGGCTTTATATAATAAGATAATAAAAGAG
GATAGAGATTCCTATATTGTTACCAGGCCCCACTGCAATTTTATGAATAAACCGGTAATAACTGTAGCCAGGGTATTTAA
CCCGGGAAGTCCGGAAGAAAAAGTTATGATAAGTGCTGATATCTCCCTTGATATTCTGGATAGTATTACCGGTGTTAAGC
TCGGGAAAAAAGGATATGTATTTGTTGTTGATAGGCTGGGTAATATTATATATCATCCAGATCGCAAGTTGATAGGTAGT
AAAAGTCAGTTTATAAATACTGGATGGTTAAAAAGCGGTAGCAATAACAGGATTATTTCCAGAGAGGGCAAACAATATAT
TCTCACCTATACCGTATCCCGGAAAACAGGATGGTATATTGTTAGTCTGGCTCCAGCCCGCGAGATAAGCGGGCAACTCC
ATCAGTTAAAAAATATTACCCTGGGTATTATTTTACTGGTATTGCTAACAGTAGTGCTACTAACTGTTTACTTATCAAAT
ACGTTAACCCGACCAATCCGGAAACTGGAGCATCTTACCAACAGGGCTGCCAATAATGACCTGAGTGTCAAGATTAAAAT
CAGTGGTAATGACGAAATTGCCCAGCTGGGTAACAGCTTTAATAAAATGATTGAAAGAATTAAGAAGCTAATGCAGGAAA
ATATTGAGGAACAGAAGCTTATTAGAAAACTTGAGATGGAAAGTCTGGAAAATCAGATAAAACCCCATTTTATTTATAAT
ACCCTTGATTTAATTATCGGTTATCTTGAAAGTAATAACAGTAAAAAGGCTTCTTTTTTGATAGAAGCTCTGGGTAAATT
CTTCCGGTTAAGCCTGAGCCATGGTAAAGAACTGGTCATGGTTAAAAATGAGATTGAACATGTCAAAAACTATCTTTATA
TCCAGCAGCAGCGCCATGGTGAAGAATATGAGTATATTATTGATATTAAGGATAAAGAAATACTTACTGAATATATGCCC
AAGTTACTCCTTCAACCCCTGGTTGAGAATGCTATCTACCACGGAATACTGAAGGTGAATAAAAGCGGCCTAATTATTGT
TAGAGGTTATCGTAAGGGAGAAGATATTTTCTTTGATGTAATAGATAATGGAGTGGGAATGTCCCGGGAGAAGGTTGACG
AAATAAATTCAATATTGAGGGGGGAAATGGGGGTAGAGGACGAAAAACAGTATTTCGGCCTCAGAAATGTCAATGAAAGG
ATTAAACTAAAGTTTGGACCCGACTACGGGCTCTATCTCGATAGTGATATAGGGGCCGGTACTAAGGCTACCATCAAGAT
TGGAGTTATTAAAAATGATGGTGATTAG

Upstream 100 bases:

>100_bases
CGGTATTGAGCATGCCAACACCAGTAATATTGATAGGCTACTTAAAGTTCATAAACCATGGGGTGTCAGATAATTTGTCT
GGCAGATAGGGGTTGATGTT

Downstream 100 bases:

>100_bases
GGTAAGTTACAATTAAATAATTTACAGACAGGATTAAGTATTTATGGCTCCTGACGAAAATTAATTTTAAGCTGGGGCTA
CAGTAGAATGCTTAATCCTG

Product: histidine kinase internal region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MKALKKIMQTLSSLFQIQTLRTKLVFSFLLFGLVPFLIFAFFSYNKYLGALQERITTYSEGVVSRMQKDLDEYLQDVNSL
LNMKDDYYINQFIKLKRAGDFEGNRKYTFRLWEDFSTLTRIKEGIEDVALTFDDGKRFSTYGLYYAIPETMALYNKIIKE
DRDSYIVTRPHCNFMNKPVITVARVFNPGSPEEKVMISADISLDILDSITGVKLGKKGYVFVVDRLGNIIYHPDRKLIGS
KSQFINTGWLKSGSNNRIISREGKQYILTYTVSRKTGWYIVSLAPAREISGQLHQLKNITLGIILLVLLTVVLLTVYLSN
TLTRPIRKLEHLTNRAANNDLSVKIKISGNDEIAQLGNSFNKMIERIKKLMQENIEEQKLIRKLEMESLENQIKPHFIYN
TLDLIIGYLESNNSKKASFLIEALGKFFRLSLSHGKELVMVKNEIEHVKNYLYIQQQRHGEEYEYIIDIKDKEILTEYMP
KLLLQPLVENAIYHGILKVNKSGLIIVRGYRKGEDIFFDVIDNGVGMSREKVDEINSILRGEMGVEDEKQYFGLRNVNER
IKLKFGPDYGLYLDSDIGAGTKATIKIGVIKNDGD

Sequences:

>Translated_595_residues
MKALKKIMQTLSSLFQIQTLRTKLVFSFLLFGLVPFLIFAFFSYNKYLGALQERITTYSEGVVSRMQKDLDEYLQDVNSL
LNMKDDYYINQFIKLKRAGDFEGNRKYTFRLWEDFSTLTRIKEGIEDVALTFDDGKRFSTYGLYYAIPETMALYNKIIKE
DRDSYIVTRPHCNFMNKPVITVARVFNPGSPEEKVMISADISLDILDSITGVKLGKKGYVFVVDRLGNIIYHPDRKLIGS
KSQFINTGWLKSGSNNRIISREGKQYILTYTVSRKTGWYIVSLAPAREISGQLHQLKNITLGIILLVLLTVVLLTVYLSN
TLTRPIRKLEHLTNRAANNDLSVKIKISGNDEIAQLGNSFNKMIERIKKLMQENIEEQKLIRKLEMESLENQIKPHFIYN
TLDLIIGYLESNNSKKASFLIEALGKFFRLSLSHGKELVMVKNEIEHVKNYLYIQQQRHGEEYEYIIDIKDKEILTEYMP
KLLLQPLVENAIYHGILKVNKSGLIIVRGYRKGEDIFFDVIDNGVGMSREKVDEINSILRGEMGVEDEKQYFGLRNVNER
IKLKFGPDYGLYLDSDIGAGTKATIKIGVIKNDGD
>Mature_595_residues
MKALKKIMQTLSSLFQIQTLRTKLVFSFLLFGLVPFLIFAFFSYNKYLGALQERITTYSEGVVSRMQKDLDEYLQDVNSL
LNMKDDYYINQFIKLKRAGDFEGNRKYTFRLWEDFSTLTRIKEGIEDVALTFDDGKRFSTYGLYYAIPETMALYNKIIKE
DRDSYIVTRPHCNFMNKPVITVARVFNPGSPEEKVMISADISLDILDSITGVKLGKKGYVFVVDRLGNIIYHPDRKLIGS
KSQFINTGWLKSGSNNRIISREGKQYILTYTVSRKTGWYIVSLAPAREISGQLHQLKNITLGIILLVLLTVVLLTVYLSN
TLTRPIRKLEHLTNRAANNDLSVKIKISGNDEIAQLGNSFNKMIERIKKLMQENIEEQKLIRKLEMESLENQIKPHFIYN
TLDLIIGYLESNNSKKASFLIEALGKFFRLSLSHGKELVMVKNEIEHVKNYLYIQQQRHGEEYEYIIDIKDKEILTEYMP
KLLLQPLVENAIYHGILKVNKSGLIIVRGYRKGEDIFFDVIDNGVGMSREKVDEINSILRGEMGVEDEKQYFGLRNVNER
IKLKFGPDYGLYLDSDIGAGTKATIKIGVIKNDGD

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=240, Percent_Identity=28.75, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788723, Length=219, Percent_Identity=30.1369863013699, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68503; Mature: 68503

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALKKIMQTLSSLFQIQTLRTKLVFSFLLFGLVPFLIFAFFSYNKYLGALQERITTYSE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVVSRMQKDLDEYLQDVNSLLNMKDDYYINQFIKLKRAGDFEGNRKYTFRLWEDFSTLTR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHH
IKEGIEDVALTFDDGKRFSTYGLYYAIPETMALYNKIIKEDRDSYIVTRPHCNFMNKPVI
HHHCHHHEEEEECCCCEEEECEEEEECHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHH
TVARVFNPGSPEEKVMISADISLDILDSITGVKLGKKGYVFVVDRLGNIIYHPDRKLIGS
HHHHHCCCCCCCCCEEEEECCCHHHHHCCCCCEECCCCCEEEEEHHCCEEECCCHHHHCC
KSQFINTGWLKSGSNNRIISREGKQYILTYTVSRKTGWYIVSLAPAREISGQLHQLKNIT
CHHHEECCCCCCCCCCCEEECCCCEEEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHH
LGIILLVLLTVVLLTVYLSNTLTRPIRKLEHLTNRAANNDLSVKIKISGNDEIAQLGNSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHH
NKMIERIKKLMQENIEEQKLIRKLEMESLENQIKPHFIYNTLDLIIGYLESNNSKKASFL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHH
IEALGKFFRLSLSHGKELVMVKNEIEHVKNYLYIQQQRHGEEYEYIIDIKDKEILTEYMP
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
KLLLQPLVENAIYHGILKVNKSGLIIVRGYRKGEDIFFDVIDNGVGMSREKVDEINSILR
HHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
GEMGVEDEKQYFGLRNVNERIKLKFGPDYGLYLDSDIGAGTKATIKIGVIKNDGD
CCCCCCCHHHHCCCCCCCCEEEEEECCCCCEEEECCCCCCCEEEEEEEEEECCCC
>Mature Secondary Structure
MKALKKIMQTLSSLFQIQTLRTKLVFSFLLFGLVPFLIFAFFSYNKYLGALQERITTYSE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVVSRMQKDLDEYLQDVNSLLNMKDDYYINQFIKLKRAGDFEGNRKYTFRLWEDFSTLTR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHH
IKEGIEDVALTFDDGKRFSTYGLYYAIPETMALYNKIIKEDRDSYIVTRPHCNFMNKPVI
HHHCHHHEEEEECCCCEEEECEEEEECHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHH
TVARVFNPGSPEEKVMISADISLDILDSITGVKLGKKGYVFVVDRLGNIIYHPDRKLIGS
HHHHHCCCCCCCCCEEEEECCCHHHHHCCCCCEECCCCCEEEEEHHCCEEECCCHHHHCC
KSQFINTGWLKSGSNNRIISREGKQYILTYTVSRKTGWYIVSLAPAREISGQLHQLKNIT
CHHHEECCCCCCCCCCCEEECCCCEEEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHH
LGIILLVLLTVVLLTVYLSNTLTRPIRKLEHLTNRAANNDLSVKIKISGNDEIAQLGNSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHH
NKMIERIKKLMQENIEEQKLIRKLEMESLENQIKPHFIYNTLDLIIGYLESNNSKKASFL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHH
IEALGKFFRLSLSHGKELVMVKNEIEHVKNYLYIQQQRHGEEYEYIIDIKDKEILTEYMP
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
KLLLQPLVENAIYHGILKVNKSGLIIVRGYRKGEDIFFDVIDNGVGMSREKVDEINSILR
HHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
GEMGVEDEKQYFGLRNVNERIKLKFGPDYGLYLDSDIGAGTKATIKIGVIKNDGD
CCCCCCCHHHHCCCCCCCCEEEEEECCCCCEEEECCCCCCCEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]