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The map label for this gene is atpI [H]

Identifier: 220932778

GI number: 220932778

Start: 2081529

End: 2083478

Strand: Reverse

Name: atpI [H]

Synonym: Hore_19440

Alternate gene names: 220932778

Gene position: 2083478-2081529 (Counterclockwise)

Preceding gene: 220932779

Following gene: 220932777

Centisome position: 80.81

GC content: 38.21

Gene sequence:

>1950_bases
ATGGCTGTTGTAACCATGAAAAAATTTCAAATTGTTGGTCATAAAAAAGAGCTTGACCCTATCTCGTACCGGGTCATTAA
CAGTGATTTTATACAACTTGAAGATTATGACTCCTTCCTTCTAAGTGACCTGCCCGGGGATGAGATTAAACCACTCAAAA
GGGAGAATCCATATTCTGGTCTTTTAAATGAAATTATTAATCTGATGGAAACCCTTAATATCAAATATGAAGATAACCCC
AGGGATAAAAATAACCTGGAAAAGGTTGAATTAGAAAAGATAAATGTTGACCAGATCAGGAAAGATATCAAACCTGTGAC
CCAGAAAATCAATAGGATATTAAGGTTTAAGAGGAAACTGGAAAAGGAAGAAGAACGTTTAAAGGACCTTAAACACCATG
TTCGCTTAATGAAGAATATTGACCTGGATATAGCTGAACTAAAGCATCTTTCATATATTTCCCTTGTATTTGGCCGGGTC
AGCAAAAATGATTATGAACGGCTCATTAAAAATATAACTGAATTACCTATTTTAATAATTGAAGTATACCGTGATGAAGA
TAATGTCTGGTTTTTTTCATTTACCAAAAAAAGTAATGAAGAAAAGGCTTTAAATATTCTGGATACGGTTTATTTTGAAA
AGTTAGATCTCCCACCCCGGGTCAAGGGCCAACCGCGGGATATTTTAGACAGGGTCGATCACAGGTTAAAGAGAATAGAA
ATTGCCTATGAAGAAATTAAGCTGGAATTCCAGAAATATGCCCATCTTTATGAAAAAAAATTAAAATCTTATTATAGAAA
GTTAAAACTTATGGACAGGATACGGGAAATAAATAATCAGTATTATGGAGAGGTTGACCATTTATTTGTGATGAGTGGCT
GGATTACAGCCACTAGGGAAATAGGGTTTAGAACAGAATTGGAAAAAGAATTCCCCAATGTTATCTATACCAGTGAAGAA
ATTGATAATCACTCCAAAGAAAAACCACCAACGGTATTGAAAAATTTCAGGTGGTTTAAGCCCTTTGAATCCCTGGTTGA
GCTTTATGGTGTTCCCCGTTACGGGGAGATAGACCCGACACCGTTTATGGCTATTACCTATCTCATTATGTTCGGAATAA
TGTTTGGGGATGTGGGCCAGGGATTAATCTTTTTCCTCCTGGGATACCTTATGAAAAATAGATACATTAAACTGGGGAGT
CCTAACAGTGGAGCCCTCCTTATGGGGCTTGGTTTTTCTTCAACGGTATTTGGTTTTCTATATGGCAGTATATTTGGTCT
CGAGCATATTTTACCGGCCCTGTGGGTTAGACCCTTTGAAAATATTATGATGTGGCTGGGTATGGCCATCGGGCTGGGTG
TAATATTAATGCTTATCAGTATGGTCTTTAATTTGATAAATTGTTTACGGAGAAAGGATATAGGTGAAGGGCTTTTTTCC
AGGTATGGCTTGACCGGTCTCTTCTTTTATTTGTTTGCACTGGCCACGGTTATATCACTGGGGTTCCGGGGGGAATTACT
GCTACATCCATTTTTGACTTTTGTTCTTTTGACTATACCCCTGGTATTGATCCTTTTTAAAGAGCCACTGGTCAACATAA
TAAACCAGGAAAAAGACATCTGGCCTGAAGATACCGGGAATTACTTCCTGGAAGCCTCTTTTGAGTTATTTGATACCCTT
ATCGGGTATTTGAGTAATACCATATCATTTGTCAGGGTGGGTGCCTTTACCCTGAACCATATAGGGTTATTTATGGCAGT
ATTTATCCTGGCCGGGATGGTTAAAAACAGTCTGGGGAGTATACTTGTCATTATAGGGGGAAATATTTTAATAATGGCTC
TCGAAGGCCTGGTTGTCGGTATTCAGGTATTGAGGCTTGAATATTTTGAGCTGTTTGGCAAATTCTTTAAAGGGGATGGC
AGGAAGTTCACACCGGCCAGGCTCCAGTAA

Upstream 100 bases:

>100_bases
AATAAGAGATATTATTACTGTTGTCGAGGGTGTCAGGTATTCTCTGAGAAGTGAAGATATTAAAAATTACCTAATAAGGG
ATTTAAAGTAGGGTGATAAT

Downstream 100 bases:

>100_bases
TTTTGACCAGGGTCTTTTATAATCGATTTTTTCTTGTCTGAAAACTGTTAATATCCTTTGTTTTATTTTCAAGCTCAAAA
AAATTAATTTTTATATATTT

Product: H(+)-transporting two-sector ATPase

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit I [H]

Number of amino acids: Translated: 649; Mature: 648

Protein sequence:

>649_residues
MAVVTMKKFQIVGHKKELDPISYRVINSDFIQLEDYDSFLLSDLPGDEIKPLKRENPYSGLLNEIINLMETLNIKYEDNP
RDKNNLEKVELEKINVDQIRKDIKPVTQKINRILRFKRKLEKEEERLKDLKHHVRLMKNIDLDIAELKHLSYISLVFGRV
SKNDYERLIKNITELPILIIEVYRDEDNVWFFSFTKKSNEEKALNILDTVYFEKLDLPPRVKGQPRDILDRVDHRLKRIE
IAYEEIKLEFQKYAHLYEKKLKSYYRKLKLMDRIREINNQYYGEVDHLFVMSGWITATREIGFRTELEKEFPNVIYTSEE
IDNHSKEKPPTVLKNFRWFKPFESLVELYGVPRYGEIDPTPFMAITYLIMFGIMFGDVGQGLIFFLLGYLMKNRYIKLGS
PNSGALLMGLGFSSTVFGFLYGSIFGLEHILPALWVRPFENIMMWLGMAIGLGVILMLISMVFNLINCLRRKDIGEGLFS
RYGLTGLFFYLFALATVISLGFRGELLLHPFLTFVLLTIPLVLILFKEPLVNIINQEKDIWPEDTGNYFLEASFELFDTL
IGYLSNTISFVRVGAFTLNHIGLFMAVFILAGMVKNSLGSILVIIGGNILIMALEGLVVGIQVLRLEYFELFGKFFKGDG
RKFTPARLQ

Sequences:

>Translated_649_residues
MAVVTMKKFQIVGHKKELDPISYRVINSDFIQLEDYDSFLLSDLPGDEIKPLKRENPYSGLLNEIINLMETLNIKYEDNP
RDKNNLEKVELEKINVDQIRKDIKPVTQKINRILRFKRKLEKEEERLKDLKHHVRLMKNIDLDIAELKHLSYISLVFGRV
SKNDYERLIKNITELPILIIEVYRDEDNVWFFSFTKKSNEEKALNILDTVYFEKLDLPPRVKGQPRDILDRVDHRLKRIE
IAYEEIKLEFQKYAHLYEKKLKSYYRKLKLMDRIREINNQYYGEVDHLFVMSGWITATREIGFRTELEKEFPNVIYTSEE
IDNHSKEKPPTVLKNFRWFKPFESLVELYGVPRYGEIDPTPFMAITYLIMFGIMFGDVGQGLIFFLLGYLMKNRYIKLGS
PNSGALLMGLGFSSTVFGFLYGSIFGLEHILPALWVRPFENIMMWLGMAIGLGVILMLISMVFNLINCLRRKDIGEGLFS
RYGLTGLFFYLFALATVISLGFRGELLLHPFLTFVLLTIPLVLILFKEPLVNIINQEKDIWPEDTGNYFLEASFELFDTL
IGYLSNTISFVRVGAFTLNHIGLFMAVFILAGMVKNSLGSILVIIGGNILIMALEGLVVGIQVLRLEYFELFGKFFKGDG
RKFTPARLQ
>Mature_648_residues
AVVTMKKFQIVGHKKELDPISYRVINSDFIQLEDYDSFLLSDLPGDEIKPLKRENPYSGLLNEIINLMETLNIKYEDNPR
DKNNLEKVELEKINVDQIRKDIKPVTQKINRILRFKRKLEKEEERLKDLKHHVRLMKNIDLDIAELKHLSYISLVFGRVS
KNDYERLIKNITELPILIIEVYRDEDNVWFFSFTKKSNEEKALNILDTVYFEKLDLPPRVKGQPRDILDRVDHRLKRIEI
AYEEIKLEFQKYAHLYEKKLKSYYRKLKLMDRIREINNQYYGEVDHLFVMSGWITATREIGFRTELEKEFPNVIYTSEEI
DNHSKEKPPTVLKNFRWFKPFESLVELYGVPRYGEIDPTPFMAITYLIMFGIMFGDVGQGLIFFLLGYLMKNRYIKLGSP
NSGALLMGLGFSSTVFGFLYGSIFGLEHILPALWVRPFENIMMWLGMAIGLGVILMLISMVFNLINCLRRKDIGEGLFSR
YGLTGLFFYLFALATVISLGFRGELLLHPFLTFVLLTIPLVLILFKEPLVNIINQEKDIWPEDTGNYFLEASFELFDTLI
GYLSNTISFVRVGAFTLNHIGLFMAVFILAGMVKNSLGSILVIIGGNILIMALEGLVVGIQVLRLEYFELFGKFFKGDGR
KFTPARLQ

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI19924145, Length=134, Percent_Identity=33.5820895522388, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI5174717, Length=134, Percent_Identity=33.5820895522388, Blast_Score=75, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25145796, Length=176, Percent_Identity=25, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI212645933, Length=176, Percent_Identity=25, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647955, Length=340, Percent_Identity=21.4705882352941, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357019, Length=340, Percent_Identity=21.4705882352941, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357061, Length=374, Percent_Identity=20.3208556149733, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650959, Length=169, Percent_Identity=26.0355029585799, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24650961, Length=169, Percent_Identity=26.0355029585799, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45551995, Length=169, Percent_Identity=26.0355029585799, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24650967, Length=169, Percent_Identity=26.0355029585799, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24650965, Length=169, Percent_Identity=26.0355029585799, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24650963, Length=169, Percent_Identity=26.0355029585799, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI281362794, Length=169, Percent_Identity=26.0355029585799, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI281362792, Length=169, Percent_Identity=26.0355029585799, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21358171, Length=169, Percent_Identity=26.0355029585799, Blast_Score=66, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24650956, Length=169, Percent_Identity=26.0355029585799, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 75544; Mature: 75413

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVVTMKKFQIVGHKKELDPISYRVINSDFIQLEDYDSFLLSDLPGDEIKPLKRENPYSG
CCEEEEHHHHHHCCCCCCCCHHEEEECCCEEEECCHHHHHHHCCCCCCCCCCCCCCCHHH
LLNEIINLMETLNIKYEDNPRDKNNLEKVELEKINVDQIRKDIKPVTQKINRILRFKRKL
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
EKEEERLKDLKHHVRLMKNIDLDIAELKHLSYISLVFGRVSKNDYERLIKNITELPILII
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEE
EVYRDEDNVWFFSFTKKSNEEKALNILDTVYFEKLDLPPRVKGQPRDILDRVDHRLKRIE
EEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
IAYEEIKLEFQKYAHLYEKKLKSYYRKLKLMDRIREINNQYYGEVDHLFVMSGWITATRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IGFRTELEKEFPNVIYTSEEIDNHSKEKPPTVLKNFRWFKPFESLVELYGVPRYGEIDPT
CCCHHHHHHHCCCEEEECHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCCCCCCC
PFMAITYLIMFGIMFGDVGQGLIFFLLGYLMKNRYIKLGSPNSGALLMGLGFSSTVFGFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCHHHHHHHHH
YGSIFGLEHILPALWVRPFENIMMWLGMAIGLGVILMLISMVFNLINCLRRKDIGEGLFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYGLTGLFFYLFALATVISLGFRGELLLHPFLTFVLLTIPLVLILFKEPLVNIINQEKDI
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WPEDTGNYFLEASFELFDTLIGYLSNTISFVRVGAFTLNHIGLFMAVFILAGMVKNSLGS
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ILVIIGGNILIMALEGLVVGIQVLRLEYFELFGKFFKGDGRKFTPARLQ
EEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AVVTMKKFQIVGHKKELDPISYRVINSDFIQLEDYDSFLLSDLPGDEIKPLKRENPYSG
CEEEEHHHHHHCCCCCCCCHHEEEECCCEEEECCHHHHHHHCCCCCCCCCCCCCCCHHH
LLNEIINLMETLNIKYEDNPRDKNNLEKVELEKINVDQIRKDIKPVTQKINRILRFKRKL
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
EKEEERLKDLKHHVRLMKNIDLDIAELKHLSYISLVFGRVSKNDYERLIKNITELPILII
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEE
EVYRDEDNVWFFSFTKKSNEEKALNILDTVYFEKLDLPPRVKGQPRDILDRVDHRLKRIE
EEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
IAYEEIKLEFQKYAHLYEKKLKSYYRKLKLMDRIREINNQYYGEVDHLFVMSGWITATRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IGFRTELEKEFPNVIYTSEEIDNHSKEKPPTVLKNFRWFKPFESLVELYGVPRYGEIDPT
CCCHHHHHHHCCCEEEECHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCCCCCCC
PFMAITYLIMFGIMFGDVGQGLIFFLLGYLMKNRYIKLGSPNSGALLMGLGFSSTVFGFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCHHHHHHHHH
YGSIFGLEHILPALWVRPFENIMMWLGMAIGLGVILMLISMVFNLINCLRRKDIGEGLFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYGLTGLFFYLFALATVISLGFRGELLLHPFLTFVLLTIPLVLILFKEPLVNIINQEKDI
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WPEDTGNYFLEASFELFDTLIGYLSNTISFVRVGAFTLNHIGLFMAVFILAGMVKNSLGS
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ILVIIGGNILIMALEGLVVGIQVLRLEYFELFGKFFKGDGRKFTPARLQ
EEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]