Click here to switch to the map view.

The map label for this gene is atpD [H]

Identifier: 220932772

GI number: 220932772

Start: 2076179

End: 2076805

Strand: Reverse

Name: atpD [H]

Synonym: Hore_19380

Alternate gene names: 220932772

Gene position: 2076805-2076179 (Counterclockwise)

Preceding gene: 220932773

Following gene: 220932769

Centisome position: 80.55

GC content: 40.99

Gene sequence:

>627_bases
ATGACAATGGATAGGCTTAATATATCCCCGACCAAAAGTAATCTTATTCAGGCCAAAAACTCCCTTGAACTGGCTAAAGA
GGGTTATGAGCTCCTGGATCAAAAGAGAAATGTTTTAATCAGGGAAATGATGGCCAAAATCGATGAGGCTAAAAAGATTC
AGTCTGAGATAAATGAATATTTCTATGAGGCTTATCAGGCTCTCCAGGTGGTTGATATTACCATGGGGATAGGTACAGTT
GAAGAGATTGCTACCGGTATTGATTTTATTGATGATGTTAAAATAAAGTGCTACAGTGTTATGGGGGTTGAGATCCCTGA
AGTAGAGCCGGTCTCAGAGAAGATTGAACCCAGGTACAGTTTTTTCAGGACCAATCTGGCCCTGGACCGGGCCTTTAAAA
ACTTTACAAGGGTTGTTTCCCTTATTACCAGGTTGGCCGAAATAGAGACCTCGGTTTACCGCCTGGCAACTGCCATAAAG
CAGACCCAGAAGAGGGCCAATGCCCTTGATAATATCCTTATCCCCAGGTATGAAAATACTGTTAAATTTATTGAAGATAC
CCTTGAAGAGAAAGAAAGGGAAGACTTTTTCCGTATCAAACTCGTTAAAAAGAAGAAAGAAACCTGA

Upstream 100 bases:

>100_bases
ACCCTTGATCTGGCCTGGGAGGTGTTGAGTGAACTGCCCCCGACCGAGCTTGACAGGATTTCGGGTGAAGAACTGGAAAA
ATACTACCGGGGGAGTGTCA

Downstream 100 bases:

>100_bases
AAAAAGGTCCTATTCGCCTGGAATAGGACCTTTTTATATCCTGTTTTATTAATTAATCTTTGAGGACCAGTTTTTTGAAG
TTAAATATCTCTTTCCGGGC

Product: V-type ATP synthase subunit D

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit D [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTMDRLNISPTKSNLIQAKNSLELAKEGYELLDQKRNVLIREMMAKIDEAKKIQSEINEYFYEAYQALQVVDITMGIGTV
EEIATGIDFIDDVKIKCYSVMGVEIPEVEPVSEKIEPRYSFFRTNLALDRAFKNFTRVVSLITRLAEIETSVYRLATAIK
QTQKRANALDNILIPRYENTVKFIEDTLEEKEREDFFRIKLVKKKKET

Sequences:

>Translated_208_residues
MTMDRLNISPTKSNLIQAKNSLELAKEGYELLDQKRNVLIREMMAKIDEAKKIQSEINEYFYEAYQALQVVDITMGIGTV
EEIATGIDFIDDVKIKCYSVMGVEIPEVEPVSEKIEPRYSFFRTNLALDRAFKNFTRVVSLITRLAEIETSVYRLATAIK
QTQKRANALDNILIPRYENTVKFIEDTLEEKEREDFFRIKLVKKKKET
>Mature_207_residues
TMDRLNISPTKSNLIQAKNSLELAKEGYELLDQKRNVLIREMMAKIDEAKKIQSEINEYFYEAYQALQVVDITMGIGTVE
EIATGIDFIDDVKIKCYSVMGVEIPEVEPVSEKIEPRYSFFRTNLALDRAFKNFTRVVSLITRLAEIETSVYRLATAIKQ
TQKRANALDNILIPRYENTVKFIEDTLEEKEREDFFRIKLVKKKKET

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1394

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase D subunit family [H]

Homologues:

Organism=Homo sapiens, GI7706757, Length=215, Percent_Identity=31.6279069767442, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17553636, Length=209, Percent_Identity=29.1866028708134, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320784, Length=221, Percent_Identity=29.8642533936652, Blast_Score=86, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20128937, Length=210, Percent_Identity=30, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355551, Length=210, Percent_Identity=29.0476190476191, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002699 [H]

Pfam domain/function: PF01813 ATP-synt_D [H]

EC number: 3.6.3.14

Molecular weight: Translated: 24188; Mature: 24057

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMDRLNISPTKSNLIQAKNSLELAKEGYELLDQKRNVLIREMMAKIDEAKKIQSEINEY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYEAYQALQVVDITMGIGTVEEIATGIDFIDDVKIKCYSVMGVEIPEVEPVSEKIEPRYS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHEEEECCCCCCCCCHHHHHCHHHH
FFRTNLALDRAFKNFTRVVSLITRLAEIETSVYRLATAIKQTQKRANALDNILIPRYENT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VKFIEDTLEEKEREDFFRIKLVKKKKET
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TMDRLNISPTKSNLIQAKNSLELAKEGYELLDQKRNVLIREMMAKIDEAKKIQSEINEY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYEAYQALQVVDITMGIGTVEEIATGIDFIDDVKIKCYSVMGVEIPEVEPVSEKIEPRYS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHEEEECCCCCCCCCHHHHHCHHHH
FFRTNLALDRAFKNFTRVVSLITRLAEIETSVYRLATAIKQTQKRANALDNILIPRYENT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VKFIEDTLEEKEREDFFRIKLVKKKKET
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA