Click here to switch to the map view.

The map label for this gene is kdsB [H]

Identifier: 220932728

GI number: 220932728

Start: 2023041

End: 2023766

Strand: Reverse

Name: kdsB [H]

Synonym: Hore_18930

Alternate gene names: 220932728

Gene position: 2023766-2023041 (Counterclockwise)

Preceding gene: 220932729

Following gene: 220932727

Centisome position: 78.5

GC content: 43.53

Gene sequence:

>726_bases
ATGAATGTTATAGCGGTAATTCCAGCCCGTTTTTATTCAAGCCGTTTTCCCGGCAAACCACTGGCCGATATTAAAGGAAA
ACCAATGATTGAACATGTATACCGGCGTGTTTGCCGGGTTAAAGGTCTGAAAGAAGTCTATGTTGCCACTGATGATGACA
GGATTTACAATACTGTTAAGGATTTCGGGGGCAATGCAGTTATGACTTCAAAAGCTTGTAGTTCAGGGACTGACCGGGTT
GCTGAGGTTGTTGCTAATTTAGACTGTGATATTGTGGTTAATGTCCAGGGTGATGAACCCCTGCTGGAACCACTGATGGT
GGAGCAGGCTCTCAAACCCTTTGCAGAGGAGAAAAACCTTAACATGAGTACCCTGATGAAAGAGATCGGGGACCCCGGAG
AGGTAGAAAATCCCAATGTGGTTAAGGTAGTAGTTGATAAGGATGGATATGCCCTGTATTTTTCCCGGTCACCGATTCCC
CACCCCCGGAACAGTGGGGCCCGGTATTATAAACATATTGGATTATATATATACAGACGCAAATTTTTAATGAATCTGAC
CCAGATGGAGCAGACAGAACTGGAGAAGGTTGAATCCCTGGAACAGCTCAGGGTTTTAGAAAATGGTTATAAAATTAAAG
TTGTGGAGACTGAATTTGACTCGATTGGTGTTGATACTCCTGAAGATATAGCCAGGGTGGAAAAAATTATGGAGGGGTGT
AATTAA

Upstream 100 bases:

>100_bases
TTTCATTAAAAGGGACAGTTGATCTGGCACAGGTAATCAATAAATATTAAAATAACTGTTAACTAAATAACTTAAATTAT
AAAAAGGTTAGGTGACAGGG

Downstream 100 bases:

>100_bases
AAGTGCTGGATAAAGTAAAGAAGGTTAAATTAAATCAAGATATTGTTTTTGGTGATAGCAACAGGCCACTGGTTCTCATC
GCCGGTCCCTGTGTTTTAGA

Product: 3-deoxy-D-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MNVIAVIPARFYSSRFPGKPLADIKGKPMIEHVYRRVCRVKGLKEVYVATDDDRIYNTVKDFGGNAVMTSKACSSGTDRV
AEVVANLDCDIVVNVQGDEPLLEPLMVEQALKPFAEEKNLNMSTLMKEIGDPGEVENPNVVKVVVDKDGYALYFSRSPIP
HPRNSGARYYKHIGLYIYRRKFLMNLTQMEQTELEKVESLEQLRVLENGYKIKVVETEFDSIGVDTPEDIARVEKIMEGC
N

Sequences:

>Translated_241_residues
MNVIAVIPARFYSSRFPGKPLADIKGKPMIEHVYRRVCRVKGLKEVYVATDDDRIYNTVKDFGGNAVMTSKACSSGTDRV
AEVVANLDCDIVVNVQGDEPLLEPLMVEQALKPFAEEKNLNMSTLMKEIGDPGEVENPNVVKVVVDKDGYALYFSRSPIP
HPRNSGARYYKHIGLYIYRRKFLMNLTQMEQTELEKVESLEQLRVLENGYKIKVVETEFDSIGVDTPEDIARVEKIMEGC
N
>Mature_241_residues
MNVIAVIPARFYSSRFPGKPLADIKGKPMIEHVYRRVCRVKGLKEVYVATDDDRIYNTVKDFGGNAVMTSKACSSGTDRV
AEVVANLDCDIVVNVQGDEPLLEPLMVEQALKPFAEEKNLNMSTLMKEIGDPGEVENPNVVKVVVDKDGYALYFSRSPIP
HPRNSGARYYKHIGLYIYRRKFLMNLTQMEQTELEKVESLEQLRVLENGYKIKVVETEFDSIGVDTPEDIARVEKIMEGC
N

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=249, Percent_Identity=44.1767068273092, Blast_Score=191, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27227; Mature: 27227

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIAVIPARFYSSRFPGKPLADIKGKPMIEHVYRRVCRVKGLKEVYVATDDDRIYNTVK
CCEEEEECHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
DFGGNAVMTSKACSSGTDRVAEVVANLDCDIVVNVQGDEPLLEPLMVEQALKPFAEEKNL
HCCCCEEEECCHHCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
NMSTLMKEIGDPGEVENPNVVKVVVDKDGYALYFSRSPIPHPRNSGARYYKHIGLYIYRR
CHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
KFLMNLTQMEQTELEKVESLEQLRVLENGYKIKVVETEFDSIGVDTPEDIARVEKIMEGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCC
N
C
>Mature Secondary Structure
MNVIAVIPARFYSSRFPGKPLADIKGKPMIEHVYRRVCRVKGLKEVYVATDDDRIYNTVK
CCEEEEECHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
DFGGNAVMTSKACSSGTDRVAEVVANLDCDIVVNVQGDEPLLEPLMVEQALKPFAEEKNL
HCCCCEEEECCHHCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
NMSTLMKEIGDPGEVENPNVVKVVVDKDGYALYFSRSPIPHPRNSGARYYKHIGLYIYRR
CHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
KFLMNLTQMEQTELEKVESLEQLRVLENGYKIKVVETEFDSIGVDTPEDIARVEKIMEGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA