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The map label for this gene is wecB [C]

Identifier: 220932626

GI number: 220932626

Start: 1914861

End: 1915982

Strand: Reverse

Name: wecB [C]

Synonym: Hore_17900

Alternate gene names: 220932626

Gene position: 1915982-1914861 (Counterclockwise)

Preceding gene: 220932627

Following gene: 220932625

Centisome position: 74.32

GC content: 41.8

Gene sequence:

>1122_bases
ATGGAAATTAAGACAGTAACTATTTTCGGCACGAGACCGGAAGCAATAAAAATGGCCCCTGTTGTTAAGGCTCTACAGGA
AAGTGAAAATATTGAAAATAAAATACTGGTCACTGCCCAGCACCGGGAGATGCTAGATCAGGTTTTAAGGCTTTTTCAGC
TTAAACCTGATTTTGATTTAGATATAATGAAACATAAACAGAGCCTGACCCATATTATGGCAAAGGCCCTTGAAGGAATC
GAGAAGGTGTTGACTGAAGTAACCCCTGATTTAGTCCTTGTCCATGGGGATACCTCGACAACTCTGGCCGGAGCCCTGGC
AGCCTACTATCAGAAAATACCCGTTGGCCATGTTGAGGCTGGATTAAGGACCTATGACAAATACCAGCCCTTTCCTGAAG
AATTAAACCGTCATCTTACCGGTGTAATTGCTGACCTTCATTTTGCCCCGACCGGGAAAGCGAAAAATTTTCTTCTGAAT
GAAGGGGTAGATGAAGGTAGTATTTTTGTTACCGGTAATACTGTGATTGATGCATTATTATATACGGCAAATATAGACTA
CACCTTTGAGGATCCTGTTCTTAAAGAATTTGATTTTGACAGGGGTCCTGTGATGTTATTAACCGCCCACCGGCGGGAAA
ACTGGGGACAACCTTTAGAGGATATATGTTATGCCGTTAAAGAATTGGTGGAAAACAATTCTGACCTCAGAGTAATATAC
CCGGTTCATTTAAATCCCCGTGTCCGGGAAGTAGTTTTTTCAATTCTGGGTGGGCATAACCGTATTTTACTGATAGAACC
TCTGGATTACCTCCCCTTTGTTCATTTAATGAAGTCTGTTGATATCGTCTTAACAGATTCAGGGGGGATTCAGGAAGAGG
CTCCGTCCCTTAATAAACCGGTCCTGGTCCTGAGAAATGTTACCGAACGTCCTGAGGCTGTAGAAGCGGGAACGGTTAAA
GTAGTCGGGACAGACAGGGAAAAAATATATAATGAGGTATCATGTTTATTAAATAATAAAGATGAGTATAATAAGATTGC
CCTGGCCAAAAATCCCTTCGGTGATGGTAAAGCAGCCGGAAGAATAGTAAAGATTATTGAAGACTACTTCCGTAAAAGCT
AA

Upstream 100 bases:

>100_bases
CCTGGAAGCTGGGTATTTTCTCTGTAGAGATACCCGGTGAAGGTGTTAATCCAACTTCCAGTAAAGAGATGGGTTAGTTA
GTTATAAAAGGGTGAAGGAC

Downstream 100 bases:

>100_bases
CATAGAGCAAATATACTGGAATATATGGTTTAAAGTTTAACTTATACTGTTGAAAAGCTAATCCAGGGTATTATAAAATT
AAAAGGAGAGCCATGCCATT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MEIKTVTIFGTRPEAIKMAPVVKALQESENIENKILVTAQHREMLDQVLRLFQLKPDFDLDIMKHKQSLTHIMAKALEGI
EKVLTEVTPDLVLVHGDTSTTLAGALAAYYQKIPVGHVEAGLRTYDKYQPFPEELNRHLTGVIADLHFAPTGKAKNFLLN
EGVDEGSIFVTGNTVIDALLYTANIDYTFEDPVLKEFDFDRGPVMLLTAHRRENWGQPLEDICYAVKELVENNSDLRVIY
PVHLNPRVREVVFSILGGHNRILLIEPLDYLPFVHLMKSVDIVLTDSGGIQEEAPSLNKPVLVLRNVTERPEAVEAGTVK
VVGTDREKIYNEVSCLLNNKDEYNKIALAKNPFGDGKAAGRIVKIIEDYFRKS

Sequences:

>Translated_373_residues
MEIKTVTIFGTRPEAIKMAPVVKALQESENIENKILVTAQHREMLDQVLRLFQLKPDFDLDIMKHKQSLTHIMAKALEGI
EKVLTEVTPDLVLVHGDTSTTLAGALAAYYQKIPVGHVEAGLRTYDKYQPFPEELNRHLTGVIADLHFAPTGKAKNFLLN
EGVDEGSIFVTGNTVIDALLYTANIDYTFEDPVLKEFDFDRGPVMLLTAHRRENWGQPLEDICYAVKELVENNSDLRVIY
PVHLNPRVREVVFSILGGHNRILLIEPLDYLPFVHLMKSVDIVLTDSGGIQEEAPSLNKPVLVLRNVTERPEAVEAGTVK
VVGTDREKIYNEVSCLLNNKDEYNKIALAKNPFGDGKAAGRIVKIIEDYFRKS
>Mature_373_residues
MEIKTVTIFGTRPEAIKMAPVVKALQESENIENKILVTAQHREMLDQVLRLFQLKPDFDLDIMKHKQSLTHIMAKALEGI
EKVLTEVTPDLVLVHGDTSTTLAGALAAYYQKIPVGHVEAGLRTYDKYQPFPEELNRHLTGVIADLHFAPTGKAKNFLLN
EGVDEGSIFVTGNTVIDALLYTANIDYTFEDPVLKEFDFDRGPVMLLTAHRRENWGQPLEDICYAVKELVENNSDLRVIY
PVHLNPRVREVVFSILGGHNRILLIEPLDYLPFVHLMKSVDIVLTDSGGIQEEAPSLNKPVLVLRNVTERPEAVEAGTVK
VVGTDREKIYNEVSCLLNNKDEYNKIALAKNPFGDGKAAGRIVKIIEDYFRKS

Specific function: Catalyzes The Reversible Epimerization At C-2 Of UDP-N- Acetylglucosamine (UDP-Glcnac) And Thereby Provides Bacteria With UDP-N-Acetylmannosamine (UDP-Mannac), The Activated Donor Of Mannac Residues. Also Involved In Bacteriophage N4 Adsorption. [C]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=379, Percent_Identity=53.5620052770449, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41897; Mature: 41897

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKTVTIFGTRPEAIKMAPVVKALQESENIENKILVTAQHREMLDQVLRLFQLKPDFDL
CCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCH
DIMKHKQSLTHIMAKALEGIEKVLTEVTPDLVLVHGDTSTTLAGALAAYYQKIPVGHVEA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHH
GLRTYDKYQPFPEELNRHLTGVIADLHFAPTGKAKNFLLNEGVDEGSIFVTGNTVIDALL
HHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCCHHHCCCCCCCEEEEECHHHHHHHH
YTANIDYTFEDPVLKEFDFDRGPVMLLTAHRRENWGQPLEDICYAVKELVENNSDLRVIY
HHCCCCEEECCCCHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEE
PVHLNPRVREVVFSILGGHNRILLIEPLDYLPFVHLMKSVDIVLTDSGGIQEEAPSLNKP
EEECCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCC
VLVLRNVTERPEAVEAGTVKVVGTDREKIYNEVSCLLNNKDEYNKIALAKNPFGDGKAAG
EEEEECCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHH
RIVKIIEDYFRKS
HHHHHHHHHHHCC
>Mature Secondary Structure
MEIKTVTIFGTRPEAIKMAPVVKALQESENIENKILVTAQHREMLDQVLRLFQLKPDFDL
CCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCH
DIMKHKQSLTHIMAKALEGIEKVLTEVTPDLVLVHGDTSTTLAGALAAYYQKIPVGHVEA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHH
GLRTYDKYQPFPEELNRHLTGVIADLHFAPTGKAKNFLLNEGVDEGSIFVTGNTVIDALL
HHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCCHHHCCCCCCCEEEEECHHHHHHHH
YTANIDYTFEDPVLKEFDFDRGPVMLLTAHRRENWGQPLEDICYAVKELVENNSDLRVIY
HHCCCCEEECCCCHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEE
PVHLNPRVREVVFSILGGHNRILLIEPLDYLPFVHLMKSVDIVLTDSGGIQEEAPSLNKP
EEECCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCC
VLVLRNVTERPEAVEAGTVKVVGTDREKIYNEVSCLLNNKDEYNKIALAKNPFGDGKAAG
EEEEECCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHH
RIVKIIEDYFRKS
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]