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The map label for this gene is atpA

Identifier: 220932618

GI number: 220932618

Start: 1910057

End: 1911682

Strand: Reverse

Name: atpA

Synonym: Hore_17820

Alternate gene names: 220932618

Gene position: 1911682-1910057 (Counterclockwise)

Preceding gene: 220932619

Following gene: 220932617

Centisome position: 74.15

GC content: 45.02

Gene sequence:

>1626_bases
ATGAATCTTAGACCTGAAGAAATAAGTTCTGTAATTAAAAAACAGATTGAAAATTATAAATCAGAACTGGAGACCGTCAG
TGTCGGTACCGTACTGGATGTGGGTGATGGTATTGCCCATGTATACGGTCTTGATGAAGTTATGGCTAGCGAGCTTTTGG
AGTTCCCCAATGGTGTATACGGTATGGCCTTAAACCTTGAGGAAGATAGTGTGGGTTGTGTGTTACTGGGGGATGAAACC
AGAGTAAAGGAAGGGGACACAGTAAAAAGAACCGGTCGTGTTGTTGAGGTGCCTGTCGGTGAAGAACTTCTGGGGAGGAT
AGTAAACTCCCTGGGGCAGCCCCTTGATGGTAAGGGTCAGATCAGTGTTGATAAATACAGGCCTGTTGAATCCCCGGCCC
CCAGTGTCGTTGACCGTAAACCGGTTGATACTCCTCTTCAGACCGGGTTAAAGGCCATTGATTCCATGATACCAATCGGC
CGGGGCCAGAGGGAGCTTATTATCGGTGACCGTCAGACCGGTAAAACAGCCATAGCTGTTGATACTATTATTAATCAGAA
AGATCAGGATGTTATCTGTATTTATGTTGCTATTGGACAGAAGGCTTCAACGGTGGCCCAGATTGCCGAAAGGTTAAAGG
AACATGGAGCTATGGACTATACTGTCATTGTTTCAGCATCTGCCAGTGAGCCGGCTCCCCTTCAGTATATTGCTCCATAT
GCCGGTTGTGCCATTGGTGAATACTTTATGTATGAGAAAAACCGTGATGTTCTGGTTGTCTATGATGATTTATCCAAACA
TGCTGTGGCCTATCGTTCCATGAGTCTTCTCTTGAGGAGGCCACCGGGACGTGAGGCCTATCCTGGTGATGTATTCTATC
TCCATTCGCGCTTGCTGGAGAGGGCAGCCAGGTTAAATGAAGATATGGGTGGCGGTTCTTTAACTGCCCTGCCTATAATT
GAAACCCAGGCTGGAGATGTATCGGCCTATATTCCAACCAACGTAATTTCCATTACCGATGGACAGATATACCTGGAAAG
TGAACTCTTCTTTGCCGGGGTTAGGCCGGCTATCAATGTCGGTATTTCTGTATCCAGGGTTGGAGGTGCCGCCCAGACAA
AGGCAATGAAGAAGGTAGCCGGAACCCTGCGGCTTGATTTGTCCCAGTATCGTGAACTTGAAGCTTTTGCCCAGTTCGGT
TCTGACCTTGATAAAGCTACACAGCGCCGCCTGGAACGCGGGGAGAGGATTGTTGAGGTTTTAAAACAACCCCAGTATAC
ACCTATGGATATGGAAGACCAGGTAATGATTATATATACAGTTGTTAACGGACATCTCGATGATATCCCTGTCGATAATA
TCGAGCGTTTTGAGGATGAATTCTTAAGTTATATTCACAGTAATTACCCAGAAATTCCGGAAACTATTAAAAAAACCGGA
GATCTTGATGATGAAACTGAAGAGAAACTCACCGGTGTTATAAAGGAATTTAAGGAAAACTTCAATGTCAAAGAAAACAC
CCTGCTCAATGTTGAAGAAGGCGATACCGGAGAAGAAGAAAATAATGAAGGTCACAACAAAGCTGAACAGGATACTGAGG
AAAAAGATACCGAAGAAGTTGTTTAA

Upstream 100 bases:

>100_bases
ATCGGTGACAGGTTAATAGATGGAAGTATTAAACACCAGCTTGATTCCATAAAAGAGAGCATTGAAAAAATTCCAGTAAC
AGAGTTAGGGGTGATTCAGA

Downstream 100 bases:

>100_bases
TATTTGTTCAAATCCGTGTTTTAGGGGTGAGAAAAATGGAGACGATGCGCGATATTAAAAGGCGTATTAACAGTATAAAA
AACACCCAGAAAATTACCAA

Product: ATP synthase F1 subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MNLRPEEISSVIKKQIENYKSELETVSVGTVLDVGDGIAHVYGLDEVMASELLEFPNGVYGMALNLEEDSVGCVLLGDET
RVKEGDTVKRTGRVVEVPVGEELLGRIVNSLGQPLDGKGQISVDKYRPVESPAPSVVDRKPVDTPLQTGLKAIDSMIPIG
RGQRELIIGDRQTGKTAIAVDTIINQKDQDVICIYVAIGQKASTVAQIAERLKEHGAMDYTVIVSASASEPAPLQYIAPY
AGCAIGEYFMYEKNRDVLVVYDDLSKHAVAYRSMSLLLRRPPGREAYPGDVFYLHSRLLERAARLNEDMGGGSLTALPII
ETQAGDVSAYIPTNVISITDGQIYLESELFFAGVRPAINVGISVSRVGGAAQTKAMKKVAGTLRLDLSQYRELEAFAQFG
SDLDKATQRRLERGERIVEVLKQPQYTPMDMEDQVMIIYTVVNGHLDDIPVDNIERFEDEFLSYIHSNYPEIPETIKKTG
DLDDETEEKLTGVIKEFKENFNVKENTLLNVEEGDTGEEENNEGHNKAEQDTEEKDTEEVV

Sequences:

>Translated_541_residues
MNLRPEEISSVIKKQIENYKSELETVSVGTVLDVGDGIAHVYGLDEVMASELLEFPNGVYGMALNLEEDSVGCVLLGDET
RVKEGDTVKRTGRVVEVPVGEELLGRIVNSLGQPLDGKGQISVDKYRPVESPAPSVVDRKPVDTPLQTGLKAIDSMIPIG
RGQRELIIGDRQTGKTAIAVDTIINQKDQDVICIYVAIGQKASTVAQIAERLKEHGAMDYTVIVSASASEPAPLQYIAPY
AGCAIGEYFMYEKNRDVLVVYDDLSKHAVAYRSMSLLLRRPPGREAYPGDVFYLHSRLLERAARLNEDMGGGSLTALPII
ETQAGDVSAYIPTNVISITDGQIYLESELFFAGVRPAINVGISVSRVGGAAQTKAMKKVAGTLRLDLSQYRELEAFAQFG
SDLDKATQRRLERGERIVEVLKQPQYTPMDMEDQVMIIYTVVNGHLDDIPVDNIERFEDEFLSYIHSNYPEIPETIKKTG
DLDDETEEKLTGVIKEFKENFNVKENTLLNVEEGDTGEEENNEGHNKAEQDTEEKDTEEVV
>Mature_541_residues
MNLRPEEISSVIKKQIENYKSELETVSVGTVLDVGDGIAHVYGLDEVMASELLEFPNGVYGMALNLEEDSVGCVLLGDET
RVKEGDTVKRTGRVVEVPVGEELLGRIVNSLGQPLDGKGQISVDKYRPVESPAPSVVDRKPVDTPLQTGLKAIDSMIPIG
RGQRELIIGDRQTGKTAIAVDTIINQKDQDVICIYVAIGQKASTVAQIAERLKEHGAMDYTVIVSASASEPAPLQYIAPY
AGCAIGEYFMYEKNRDVLVVYDDLSKHAVAYRSMSLLLRRPPGREAYPGDVFYLHSRLLERAARLNEDMGGGSLTALPII
ETQAGDVSAYIPTNVISITDGQIYLESELFFAGVRPAINVGISVSRVGGAAQTKAMKKVAGTLRLDLSQYRELEAFAQFG
SDLDKATQRRLERGERIVEVLKQPQYTPMDMEDQVMIIYTVVNGHLDDIPVDNIERFEDEFLSYIHSNYPEIPETIKKTG
DLDDETEEKLTGVIKEFKENFNVKENTLLNVEEGDTGEEENNEGHNKAEQDTEEKDTEEVV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=503, Percent_Identity=59.8409542743539, Blast_Score=627, Evalue=1e-180,
Organism=Homo sapiens, GI4757810, Length=503, Percent_Identity=59.8409542743539, Blast_Score=627, Evalue=1e-180,
Organism=Homo sapiens, GI19913428, Length=301, Percent_Identity=27.906976744186, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI19913426, Length=304, Percent_Identity=26.9736842105263, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI32189394, Length=373, Percent_Identity=24.1286863270777, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI19913424, Length=265, Percent_Identity=26.0377358490566, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1790172, Length=509, Percent_Identity=56.5815324165029, Blast_Score=599, Evalue=1e-172,
Organism=Escherichia coli, GI1790170, Length=451, Percent_Identity=24.390243902439, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788251, Length=318, Percent_Identity=28.6163522012579, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=504, Percent_Identity=59.1269841269841, Blast_Score=625, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI71988080, Length=504, Percent_Identity=59.1269841269841, Blast_Score=623, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI71988074, Length=504, Percent_Identity=55.3571428571429, Blast_Score=567, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI17510931, Length=378, Percent_Identity=27.5132275132275, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17570191, Length=298, Percent_Identity=27.8523489932886, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=415, Percent_Identity=23.6144578313253, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17509265, Length=51, Percent_Identity=56.8627450980392, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=264, Percent_Identity=26.5151515151515, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71988068, Length=73, Percent_Identity=41.0958904109589, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=506, Percent_Identity=58.695652173913, Blast_Score=612, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6319603, Length=305, Percent_Identity=28.8524590163934, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6322581, Length=419, Percent_Identity=26.0143198090692, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24658560, Length=508, Percent_Identity=61.0236220472441, Blast_Score=638, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=27.2425249169435, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=27.2425249169435, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=27.2425249169435, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24638766, Length=429, Percent_Identity=24.7086247086247, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28574560, Length=420, Percent_Identity=25.7142857142857, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=27.843137254902, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=27.843137254902, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=27.843137254902, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583992, Length=255, Percent_Identity=27.843137254902, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI20129479, Length=260, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_HALOH (B8CZ12)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002509526.1
- ProteinModelPortal:   B8CZ12
- SMR:   B8CZ12
- GeneID:   7313704
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_17820
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- ProtClustDB:   CLSK2806549
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 59752; Mature: 59752

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRPEEISSVIKKQIENYKSELETVSVGTVLDVGDGIAHVYGLDEVMASELLEFPNGVY
CCCCHHHHHHHHHHHHHHHHHHHHEEECCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCE
GMALNLEEDSVGCVLLGDETRVKEGDTVKRTGRVVEVPVGEELLGRIVNSLGQPLDGKGQ
EEEEEECCCCCCEEEECCCCCCCCCCCHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCC
ISVDKYRPVESPAPSVVDRKPVDTPLQTGLKAIDSMIPIGRGQRELIIGDRQTGKTAIAV
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEE
DTIINQKDQDVICIYVAIGQKASTVAQIAERLKEHGAMDYTVIVSASASEPAPLQYIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEECCH
AGCAIGEYFMYEKNRDVLVVYDDLSKHAVAYRSMSLLLRRPPGREAYPGDVFYLHSRLLE
HHHHHHHHHEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAARLNEDMGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIYLESELFFAGVRPAINV
HHHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCEEEECCCHHHHC
GISVSRVGGAAQTKAMKKVAGTLRLDLSQYRELEAFAQFGSDLDKATQRRLERGERIVEV
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LKQPQYTPMDMEDQVMIIYTVVNGHLDDIPVDNIERFEDEFLSYIHSNYPEIPETIKKTG
HHCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
DLDDETEEKLTGVIKEFKENFNVKENTLLNVEEGDTGEEENNEGHNKAEQDTEEKDTEEV
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCC
V
C
>Mature Secondary Structure
MNLRPEEISSVIKKQIENYKSELETVSVGTVLDVGDGIAHVYGLDEVMASELLEFPNGVY
CCCCHHHHHHHHHHHHHHHHHHHHEEECCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCE
GMALNLEEDSVGCVLLGDETRVKEGDTVKRTGRVVEVPVGEELLGRIVNSLGQPLDGKGQ
EEEEEECCCCCCEEEECCCCCCCCCCCHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCC
ISVDKYRPVESPAPSVVDRKPVDTPLQTGLKAIDSMIPIGRGQRELIIGDRQTGKTAIAV
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEE
DTIINQKDQDVICIYVAIGQKASTVAQIAERLKEHGAMDYTVIVSASASEPAPLQYIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEECCH
AGCAIGEYFMYEKNRDVLVVYDDLSKHAVAYRSMSLLLRRPPGREAYPGDVFYLHSRLLE
HHHHHHHHHEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAARLNEDMGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIYLESELFFAGVRPAINV
HHHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCEEEECCCHHHHC
GISVSRVGGAAQTKAMKKVAGTLRLDLSQYRELEAFAQFGSDLDKATQRRLERGERIVEV
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LKQPQYTPMDMEDQVMIIYTVVNGHLDDIPVDNIERFEDEFLSYIHSNYPEIPETIKKTG
HHCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
DLDDETEEKLTGVIKEFKENFNVKENTLLNVEEGDTGEEENNEGHNKAEQDTEEKDTEEV
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA