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The map label for this gene is 220932428

Identifier: 220932428

GI number: 220932428

Start: 1705287

End: 1706252

Strand: Reverse

Name: 220932428

Synonym: Hore_15920

Alternate gene names: NA

Gene position: 1706252-1705287 (Counterclockwise)

Preceding gene: 220932429

Following gene: 220932427

Centisome position: 66.18

GC content: 36.34

Gene sequence:

>966_bases
ATGGTTGATTCCTTAAAATTTTGCAAAAAAATGCTGCCAAAGGTTTCAAGAAGTTTTGCCCTTACCATACCATTACTTGA
TGATAAGCTTTATATGCCTGTTTTGACTGTATACCTTCAGGATAGATTACTGGATAATTTTGAAGATGAAGTTAAGGGGA
TAGATATTGATACCAGAAAAGATTTAATGGATAGTGTAGTTGCCCTTTTTGACCCGGATAATGAGGGAACAAATTATATT
TGCAACCGGTTAAAGGGCTATTCTGACTATATTCCTGATAATGATTTACAGGCCTTGACCGAAGGGTGCCATTTGTTAAA
AGAAGTATACCAGAATTTACCCCATAAGGTTCAGAGGCTATCCTTTAAATGGTTAAATGAGATGAATGAGGGAATGAAAA
AATACTTAACTCTCAAGATTAAAACCTTTGAAGAACTTGATGAATATTGTTATTATGTAGCCGGTACAGTTGGAGGATTT
TTAACTGAACTGGTACTCCTTTACGGTGATATCCATGATCATAAACAGAAGGAAGATCTCTTAGAAAATTTCACAGAGGC
CGGGTTGTTTCTGCAGAAAATAAATATAATCAGGGATATAAAAATAGATTTAGAGGAACGGAACAAATCTTTCTGGCCCA
TGGAAGAACTGGGATTATCGGATGAAAAAATTTTAAATCCTGATTATAAAGAAGATGCCAGCCGTGCCCTCAGGGTAATG
CTTTCTAATGCAAAGGGGCATATTGAAGGACTGGCTACATACTTTGAAGCCATACCTGATAATCTGCCGGGTTACAGGAA
ATTTTTCAGTGTTAATAATGCACTGGGAATAGCTACCCTCGAGGAACTCGAAGGAAACCTTAAACTCTTTTACGGACGGG
GCAAGGTGAAAGTCAGTAAAATGAAATTCCTGAAAATACTAAATGATCCTGTTAAATTCTTCAGACAGATGGTAATAAGA
TATTAG

Upstream 100 bases:

>100_bases
AATGCTGGAACTCAGTTTGACCCGGAACTGACCGGAAAATTTTTAGATGTTGTAACTGAAGAGTGGGTACTTAGTTCATC
ATGATGAGGTGTTGTTTTAA

Downstream 100 bases:

>100_bases
CGGAGTCAAAATATATTGACAGGTATAATTCTCCCGGGTGCCGGAAATAATTAATACAAAAGCTACCCGGGGGGTGATTT
TATGAAGTACAGGGAGTATT

Product: Squalene synthase

Products: NA

Alternate protein names: Farnesyl-Diphosphate Farnesyltransferase; Squalene Synthase; Squalene And Phytoene Synthase; Phytoene/Squalene Synthetase Family Protein; Squalene/Phytoene Synthase-Like Protein; SQS PSY Squalene/Phytoene Synthase-Like Protein

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MVDSLKFCKKMLPKVSRSFALTIPLLDDKLYMPVLTVYLQDRLLDNFEDEVKGIDIDTRKDLMDSVVALFDPDNEGTNYI
CNRLKGYSDYIPDNDLQALTEGCHLLKEVYQNLPHKVQRLSFKWLNEMNEGMKKYLTLKIKTFEELDEYCYYVAGTVGGF
LTELVLLYGDIHDHKQKEDLLENFTEAGLFLQKINIIRDIKIDLEERNKSFWPMEELGLSDEKILNPDYKEDASRALRVM
LSNAKGHIEGLATYFEAIPDNLPGYRKFFSVNNALGIATLEELEGNLKLFYGRGKVKVSKMKFLKILNDPVKFFRQMVIR
Y

Sequences:

>Translated_321_residues
MVDSLKFCKKMLPKVSRSFALTIPLLDDKLYMPVLTVYLQDRLLDNFEDEVKGIDIDTRKDLMDSVVALFDPDNEGTNYI
CNRLKGYSDYIPDNDLQALTEGCHLLKEVYQNLPHKVQRLSFKWLNEMNEGMKKYLTLKIKTFEELDEYCYYVAGTVGGF
LTELVLLYGDIHDHKQKEDLLENFTEAGLFLQKINIIRDIKIDLEERNKSFWPMEELGLSDEKILNPDYKEDASRALRVM
LSNAKGHIEGLATYFEAIPDNLPGYRKFFSVNNALGIATLEELEGNLKLFYGRGKVKVSKMKFLKILNDPVKFFRQMVIR
Y
>Mature_321_residues
MVDSLKFCKKMLPKVSRSFALTIPLLDDKLYMPVLTVYLQDRLLDNFEDEVKGIDIDTRKDLMDSVVALFDPDNEGTNYI
CNRLKGYSDYIPDNDLQALTEGCHLLKEVYQNLPHKVQRLSFKWLNEMNEGMKKYLTLKIKTFEELDEYCYYVAGTVGGF
LTELVLLYGDIHDHKQKEDLLENFTEAGLFLQKINIIRDIKIDLEERNKSFWPMEELGLSDEKILNPDYKEDASRALRVM
LSNAKGHIEGLATYFEAIPDNLPGYRKFFSVNNALGIATLEELEGNLKLFYGRGKVKVSKMKFLKILNDPVKFFRQMVIR
Y

Specific function: Unknown

COG id: COG1562

COG function: function code I; Phytoene/squalene synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI67089147, Length=313, Percent_Identity=29.7124600638978, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321984, Length=307, Percent_Identity=27.6872964169381, Blast_Score=83, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37322; Mature: 37322

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS01044 SQUALEN_PHYTOEN_SYN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA