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The map label for this gene is yggV [C]

Identifier: 220932374

GI number: 220932374

Start: 1646760

End: 1647368

Strand: Reverse

Name: yggV [C]

Synonym: Hore_15380

Alternate gene names: 220932374

Gene position: 1647368-1646760 (Counterclockwise)

Preceding gene: 220932375

Following gene: 220932373

Centisome position: 63.9

GC content: 45.98

Gene sequence:

>609_bases
ATGCCCCTTAAACTCCTTGTAGCCAGTGGTAACCAGGGGAAGATAAGGGAGATAAAAAAATACCTTAATGACCTTGATAT
AGAGATTGTTGGCCTTGACGATTTCTCCCTGCCCCCGGTTGAGGAAGATGGGGAAACCTTTTATGAAAATGCCCTCAAAA
AGGCCCGGACCAGAGCCCGGGAGACGGGTCTTTTGACTCTGGCCGATGATTCTGGCCTTGAAGTAGATTACTTGCAGGGA
AAACCCGGGGTCTATTCAGCCCGTTATGCCGGGGCAGGGGCCAGTGATGAAGATAATAATAAAAAGCTGCTGGAAGAATT
AAAAGGGGTCCCGGCTGGCCAGAGAGGGGCCCGGTTTAAGTGTGTTATGGTTTTATATGACCCTGAATTAGGCGAAGATA
TTTCCGTTACTGGAAGCTGTGAGGGGATAATTATGGAAAAACCCCGGGGTGATAATGGTTTTGGTTATGATCCCCTGTTT
TATGTCCCTGAATATGGTAAAACTATGGCTGAATTAACCCTTGAGACCAAAAATAAAATCAGCCACCGGGCCAGGGCCCT
CTCCAAGATAAAAAAGGTCATAAAAGATAGATATACAGAGAATGAATGA

Upstream 100 bases:

>100_bases
CCTTCTCCCGGGACCAGATGAATACTTTGATGGACCTGGCTGAAAAGGGAATCAGGGAACTGGTTTCCTTCCAGAAAAAG
AGCCTGGGGATTGAGGAATA

Downstream 100 bases:

>100_bases
TTATATTGACTATAATCTATTATAAAGGTCTATAATTACCGATATTTAATTTTGATAATTTGGTTTAGATGAGTTATACT
ATTAATTGCTTTCAGCGAGT

Product: non-canonical purine NTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MPLKLLVASGNQGKIREIKKYLNDLDIEIVGLDDFSLPPVEEDGETFYENALKKARTRARETGLLTLADDSGLEVDYLQG
KPGVYSARYAGAGASDEDNNKKLLEELKGVPAGQRGARFKCVMVLYDPELGEDISVTGSCEGIIMEKPRGDNGFGYDPLF
YVPEYGKTMAELTLETKNKISHRARALSKIKKVIKDRYTENE

Sequences:

>Translated_202_residues
MPLKLLVASGNQGKIREIKKYLNDLDIEIVGLDDFSLPPVEEDGETFYENALKKARTRARETGLLTLADDSGLEVDYLQG
KPGVYSARYAGAGASDEDNNKKLLEELKGVPAGQRGARFKCVMVLYDPELGEDISVTGSCEGIIMEKPRGDNGFGYDPLF
YVPEYGKTMAELTLETKNKISHRARALSKIKKVIKDRYTENE
>Mature_201_residues
PLKLLVASGNQGKIREIKKYLNDLDIEIVGLDDFSLPPVEEDGETFYENALKKARTRARETGLLTLADDSGLEVDYLQGK
PGVYSARYAGAGASDEDNNKKLLEELKGVPAGQRGARFKCVMVLYDPELGEDISVTGSCEGIIMEKPRGDNGFGYDPLFY
VPEYGKTMAELTLETKNKISHRARALSKIKKVIKDRYTENE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=194, Percent_Identity=48.9690721649485, Blast_Score=183, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI17556833, Length=197, Percent_Identity=29.9492385786802, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920712, Length=201, Percent_Identity=30.3482587064677, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22429; Mature: 22298

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKLLVASGNQGKIREIKKYLNDLDIEIVGLDDFSLPPVEEDGETFYENALKKARTRAR
CCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ETGLLTLADDSGLEVDYLQGKPGVYSARYAGAGASDEDNNKKLLEELKGVPAGQRGARFK
HCCEEEEECCCCCEEEEECCCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCEEE
CVMVLYDPELGEDISVTGSCEGIIMEKPRGDNGFGYDPLFYVPEYGKTMAELTLETKNKI
EEEEEECCCCCCCEEECCCCCEEEEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
SHRARALSKIKKVIKDRYTENE
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PLKLLVASGNQGKIREIKKYLNDLDIEIVGLDDFSLPPVEEDGETFYENALKKARTRAR
CEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ETGLLTLADDSGLEVDYLQGKPGVYSARYAGAGASDEDNNKKLLEELKGVPAGQRGARFK
HCCEEEEECCCCCEEEEECCCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCEEE
CVMVLYDPELGEDISVTGSCEGIIMEKPRGDNGFGYDPLFYVPEYGKTMAELTLETKNKI
EEEEEECCCCCCCEEECCCCCEEEEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
SHRARALSKIKKVIKDRYTENE
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA