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The map label for this gene is bglA [H]

Identifier: 220932364

GI number: 220932364

Start: 1634267

End: 1635622

Strand: Reverse

Name: bglA [H]

Synonym: Hore_15280

Alternate gene names: 220932364

Gene position: 1635622-1634267 (Counterclockwise)

Preceding gene: 220932365

Following gene: 220932362

Centisome position: 63.44

GC content: 43.07

Gene sequence:

>1356_bases
ATGGCAAAAATAATATTTCCAGAAGATTTTATCTGGGGAGCAGCTACGTCATCCTACCAGATAGAAGGAGCTTTTAATGA
GGATGGAAAGGGAGAATCCATCTGGGACAGATTTAGCCATACCCCGGGAAAAATTGAAAACGGTGACACCGGTGATATAG
CCTGTGATCATTATCATCTGTACCGGGAAGATATTGAATTAATGAAAGAGATAGGGATTAGGTCATACCGTTTTTCTACT
TCCTGGCCCCGGATTCTTCCGGAAGGTAAAGGCAGGGTAAACCAGAAAGGTCTTGATTTTTATAAAAGACTGGTTGACAA
TCTTCTTAAGGCCAATATCAGACCCATGATAACCCTATACCACTGGGATTTACCCCAGGCATTACAGGATAAAGGTGGCT
GGACCAACAGGGATACAGCCAAATATTTCGCTGAATATGCCAGGCTTATGTTTGAAGAGTTTAACGGCCTGGTGGACCTC
TGGGTTACCCATAATGAACCCTGGGTAGTTGCCTTTGAGGGTCATGCTTTTGGTAACCATGCCCCCGGTACTAAAGATTT
TAAAACGGCCCTTCAGGTCGCCCATCACCTGTTATTATCCCATGGAATGGCTGTTGATATCTTCAGGGAGGAAGACCTGC
CCGGGGAGATTGGTATTACTCTCAACTTAACCCCTGCTTACCCGGCCGGTGACAGTGAGAAGGATGTTAAGGCAGCTTCT
TTACTTGATGACTATATTAATGCATGGTTTTTATCTCCAGTGTTCAAGGGCAGTTACCCGGAGGAATTACACCACATCTA
TGAACAGAATTTAGGGGCCTTTACAACCCAACCGGGTGATATGGATATAATAAGCAGGGATATTGACTTCCTGGGCATTA
ATTACTACTCCAGGATGGTGGTCAGGCATAAACCGGGAGATAATTTGTTTAATGCTGAAGTTGTAAAAATGGAGGATAGG
CCATCTACAGAGATGGGCTGGGAGATTTATCCCCAGGGACTTTATGATATTTTAGTGAGGGTTAATAAAGAATATACCGA
TAAGCCCCTTTACATAACAGAAAACGGGGCAGCTTTTGATGACAAATTAACAGAGGAAGGTAAGATCCATGATGAGAAGA
GGATTAACTACCTGGGGGATCATTTTAAGCAGGCATATAAAGCCCTTAAAGATGGAGTTCCCCTCAGAGGTTATTATGTG
TGGTCATTGATGGATAATTTTGAATGGGCCTATGGCTATAGCAAGCGCTTTGGTCTCATTTATGTTGATTATGAAAATGG
TAACAGACGCTTTTTAAAAGATAGTGCCCTATGGTATCGGGAGGTCATCGAAAAAGGCCAGGTTGAAGCTAACTAA

Upstream 100 bases:

>100_bases
GGGGATTTGTTTGCTATATGATGCTAAAAATATTATAATGTAATCATCAGATACTATCTTAAAACATATTAGATAGACTG
TAAGGGAGGCAATATAAACA

Downstream 100 bases:

>100_bases
ACCTGTACTATAGTTAGTAAAAGGTTATTTATGACCAGAACCTATGACTAGAACCGGATAGATTAATTATTCCCGGGGAA
GCAAAAAACATATAGCAGCA

Product: family 1 glycoside hydrolase

Products: NA

Alternate protein names: Beta-D-glucoside glucohydrolase; Cellobiase; Gentiobiase [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MAKIIFPEDFIWGAATSSYQIEGAFNEDGKGESIWDRFSHTPGKIENGDTGDIACDHYHLYREDIELMKEIGIRSYRFST
SWPRILPEGKGRVNQKGLDFYKRLVDNLLKANIRPMITLYHWDLPQALQDKGGWTNRDTAKYFAEYARLMFEEFNGLVDL
WVTHNEPWVVAFEGHAFGNHAPGTKDFKTALQVAHHLLLSHGMAVDIFREEDLPGEIGITLNLTPAYPAGDSEKDVKAAS
LLDDYINAWFLSPVFKGSYPEELHHIYEQNLGAFTTQPGDMDIISRDIDFLGINYYSRMVVRHKPGDNLFNAEVVKMEDR
PSTEMGWEIYPQGLYDILVRVNKEYTDKPLYITENGAAFDDKLTEEGKIHDEKRINYLGDHFKQAYKALKDGVPLRGYYV
WSLMDNFEWAYGYSKRFGLIYVDYENGNRRFLKDSALWYREVIEKGQVEAN

Sequences:

>Translated_451_residues
MAKIIFPEDFIWGAATSSYQIEGAFNEDGKGESIWDRFSHTPGKIENGDTGDIACDHYHLYREDIELMKEIGIRSYRFST
SWPRILPEGKGRVNQKGLDFYKRLVDNLLKANIRPMITLYHWDLPQALQDKGGWTNRDTAKYFAEYARLMFEEFNGLVDL
WVTHNEPWVVAFEGHAFGNHAPGTKDFKTALQVAHHLLLSHGMAVDIFREEDLPGEIGITLNLTPAYPAGDSEKDVKAAS
LLDDYINAWFLSPVFKGSYPEELHHIYEQNLGAFTTQPGDMDIISRDIDFLGINYYSRMVVRHKPGDNLFNAEVVKMEDR
PSTEMGWEIYPQGLYDILVRVNKEYTDKPLYITENGAAFDDKLTEEGKIHDEKRINYLGDHFKQAYKALKDGVPLRGYYV
WSLMDNFEWAYGYSKRFGLIYVDYENGNRRFLKDSALWYREVIEKGQVEAN
>Mature_450_residues
AKIIFPEDFIWGAATSSYQIEGAFNEDGKGESIWDRFSHTPGKIENGDTGDIACDHYHLYREDIELMKEIGIRSYRFSTS
WPRILPEGKGRVNQKGLDFYKRLVDNLLKANIRPMITLYHWDLPQALQDKGGWTNRDTAKYFAEYARLMFEEFNGLVDLW
VTHNEPWVVAFEGHAFGNHAPGTKDFKTALQVAHHLLLSHGMAVDIFREEDLPGEIGITLNLTPAYPAGDSEKDVKAASL
LDDYINAWFLSPVFKGSYPEELHHIYEQNLGAFTTQPGDMDIISRDIDFLGINYYSRMVVRHKPGDNLFNAEVVKMEDRP
STEMGWEIYPQGLYDILVRVNKEYTDKPLYITENGAAFDDKLTEEGKIHDEKRINYLGDHFKQAYKALKDGVPLRGYYVW
SLMDNFEWAYGYSKRFGLIYVDYENGNRRFLKDSALWYREVIEKGQVEAN

Specific function: Can Hydrolyze Salicin, Cellobiose, And Probably Arbutin. [C]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=464, Percent_Identity=41.1637931034483, Blast_Score=331, Evalue=7e-91,
Organism=Homo sapiens, GI110681710, Length=467, Percent_Identity=38.1156316916488, Blast_Score=299, Evalue=3e-81,
Organism=Homo sapiens, GI13273313, Length=479, Percent_Identity=34.2379958246347, Blast_Score=269, Evalue=4e-72,
Organism=Homo sapiens, GI24497614, Length=466, Percent_Identity=35.8369098712446, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI28376633, Length=452, Percent_Identity=32.3008849557522, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI190360571, Length=101, Percent_Identity=45.5445544554455, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1789070, Length=467, Percent_Identity=33.4047109207709, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI2367174, Length=474, Percent_Identity=33.5443037974684, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI2367270, Length=461, Percent_Identity=34.4902386117137, Blast_Score=228, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI17552856, Length=465, Percent_Identity=35.4838709677419, Blast_Score=264, Evalue=8e-71,
Organism=Caenorhabditis elegans, GI17539390, Length=470, Percent_Identity=32.7659574468085, Blast_Score=238, Evalue=6e-63,
Organism=Drosophila melanogaster, GI21356577, Length=478, Percent_Identity=36.6108786610879, Blast_Score=295, Evalue=4e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017736
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.21 [H]

Molecular weight: Translated: 52134; Mature: 52003

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIIFPEDFIWGAATSSYQIEGAFNEDGKGESIWDRFSHTPGKIENGDTGDIACDHYHL
CCEEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCEEECHHHH
YREDIELMKEIGIRSYRFSTSWPRILPEGKGRVNQKGLDFYKRLVDNLLKANIRPMITLY
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEE
HWDLPQALQDKGGWTNRDTAKYFAEYARLMFEEFNGLVDLWVTHNEPWVVAFEGHAFGNH
ECCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCC
APGTKDFKTALQVAHHLLLSHGMAVDIFREEDLPGEIGITLNLTPAYPAGDSEKDVKAAS
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHH
LLDDYINAWFLSPVFKGSYPEELHHIYEQNLGAFTTQPGDMDIISRDIDFLGINYYSRMV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEECCCCCHHHHHCCCCEEEECHHHEEE
VRHKPGDNLFNAEVVKMEDRPSTEMGWEIYPQGLYDILVRVNKEYTDKPLYITENGAAFD
EEECCCCCCCCCEEEEECCCCCCCCCCEECCCHHHHHHHHHCCCCCCCCEEEECCCCCCC
DKLTEEGKIHDEKRINYLGDHFKQAYKALKDGVPLRGYYVWSLMDNFEWAYGYSKRFGLI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCEEECCCCCEEEE
YVDYENGNRRFLKDSALWYREVIEKGQVEAN
EEEEECCCEEEEHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AKIIFPEDFIWGAATSSYQIEGAFNEDGKGESIWDRFSHTPGKIENGDTGDIACDHYHL
CEEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCEEECHHHH
YREDIELMKEIGIRSYRFSTSWPRILPEGKGRVNQKGLDFYKRLVDNLLKANIRPMITLY
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEE
HWDLPQALQDKGGWTNRDTAKYFAEYARLMFEEFNGLVDLWVTHNEPWVVAFEGHAFGNH
ECCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCC
APGTKDFKTALQVAHHLLLSHGMAVDIFREEDLPGEIGITLNLTPAYPAGDSEKDVKAAS
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHH
LLDDYINAWFLSPVFKGSYPEELHHIYEQNLGAFTTQPGDMDIISRDIDFLGINYYSRMV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEECCCCCHHHHHCCCCEEEECHHHEEE
VRHKPGDNLFNAEVVKMEDRPSTEMGWEIYPQGLYDILVRVNKEYTDKPLYITENGAAFD
EEECCCCCCCCCEEEEECCCCCCCCCCEECCCHHHHHHHHHCCCCCCCCEEEECCCCCCC
DKLTEEGKIHDEKRINYLGDHFKQAYKALKDGVPLRGYYVWSLMDNFEWAYGYSKRFGLI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCEEECCCCCEEEE
YVDYENGNRRFLKDSALWYREVIEKGQVEAN
EEEEECCCEEEEHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1909624 [H]