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The map label for this gene is mngB [H]

Identifier: 220932337

GI number: 220932337

Start: 1600795

End: 1603407

Strand: Reverse

Name: mngB [H]

Synonym: Hore_15000

Alternate gene names: 220932337

Gene position: 1603407-1600795 (Counterclockwise)

Preceding gene: 220932338

Following gene: 220932336

Centisome position: 62.19

GC content: 33.83

Gene sequence:

>2613_bases
ATGTTATCATTGTATTATGATTTGAAGGCTATTTATGATGCTGCTTATGCAGAATCTATGGATGAAAGTATAAAAAATTA
TCTTCAGTATCACTTACAACAGTTAATTAAAGAATTTCCTCTTTACGGCTGTAGCAGAGAAGAAATGGTTATGGCGATAC
CTAAAATAAAAGAATATATAAACAATAAGATTTATAAAGGACATGAACATTTTGGGAAAAACGGCAAGATTGCCCTGGTT
GCCCATTCACACCTTGATGTTGCTTACCATTGGACGGCAAAACAGGCTATTCAAAAAAATGCCAGGACAACATTAATTCA
ATTGAGATTAATGGAAGAATATCCTGATTTTAAGTATGCTCACAGTCAAGCCTGGACTTATGAAAAACTTGAAAAATATT
ATCCAGAACTTTTTGCTCAGGTGAAAGAACGAATAAAAAGTGGTCAATGGGAAATTGTAGGTGGTATGTATATTGAACCT
GATTGTAATTTAATTAGTGCTGAAAGTTTTGTTCGACAAATAGTCTATGGAAAATATTATTTTAAACAAAAATTTGGAAT
TGATGTTGATAACTGTTGGTTACCTGACGTTTTTGGTAATAGTCCAATTATGCCACAGATTTTAAAGTCTGGTGGACTTG
AATATTTCGTTACCCATAAACTGTCTGTCTGGAATGATACCAATAAATTTCCTCATAATGTCTTCCTGTGGAAAGGTTTA
GATGGTACAACGGTTAATGCCTGTATACCACCAATCCATTTTGTTACCTGGATGGATACTGAAGAGACAATAAATAACTG
GAACCAATTTCAGGATAAAAATGTGTGTGATGAAACCTTACAATTATATGGTTATGGTGATGGTGGTAGTGGTGTTACAG
ATGAGATGCTACAGTTATATGAACGTCAACAGAAGTTGCCTGGTATTCCAGAACAAAGGTTGACTACAGCTAAAGAATAT
TTACATCGTATATTTAAAGACACGAAAGATTTTGCAGTATGGGATGGAGATTTATATCTCGAAATGCACCGGGGGACTTA
TACAAGTAAGGCAAAATTAAAGAAATACAACCGACAGGGAGAATTTCTTGCCCAGGAAGTTGAAACATTATGTACAGCTT
GTGACATTTATACTGGTGATTTTAAGGTGCAGAACAAACTTAAAAATATATGGAAAAAACTGTTAGTTAACCAGTTTCAT
GATATTTTACCTGGTAGTCATACACAACCGGTTTATAAAGAAGCTATTGAGAATTATGAAGAAATGTTTACAGCTTTCAA
TAATTTAAAGGAAAAGGCCCTGAAAAAAATAACCAGTCCCGGGGATGAAATAGATTATGTTGCCTTTAATGCTTTCAGCG
ATGTTAGAAATAAAGTAGCCTATATTGATGCGAATAACTGGGATATTAAATATAATGCCCTGAAAGATGATGAGGGGAAT
ATTTATCCAGTTCAGAAGCAAATAAAAGCTGATGGTAGTATTCAGTATGCAGTAAAAATTCCTGACATCCCTGGGTTTTC
ATTAAAACAATTTAAAGCAACAAGTACTGACAAAATATCTTCATCAATGAAAGTATCTCAGACAGAAATGGAAAATGACT
ACTATATCTTGAAATTAGAATCCTCAGGAAAGATAGTAAGCCTTTATGATAAAGTAAGAGAAAAATATGTTAATACTAGG
AATGAAGTATTAAATAAATGGCAGATGTTTGAAGATAAACCCGGCGCCCTAAACGCATGGGATATTGTTGAAACTTATAA
AAATCAGGAGATTAATCTTCCTGATTGGGAAAATATAACAGTTATAGAAGATGGTCCGGTAAGTATTGCGTTAAGAATGG
AGAGGAAATTTAGTAATAGCAAAGCGGTGCAGGTCATCAGAATGTTTGATAATAAACCTCAGATTGATTTTGATACCTGG
GTCGACTGGCAAGAAGAAGAAAAGTTATTAAAAGTAGCATTCCCTGTAAATGTAAGATCCAGGACTTATTCCACTGATAC
ATCAGCAGGTGGATTTGAGAGAATGAATCATAAAAATACTGGCTGGGAACAGGGGCAATTTGAAGTTCCCTGTCATAAAT
GGGTAGACATATCTGAAGGTTTGTTTGGAGTCTCACTAATGAATGATTGTAAGTATGGATGTGATGTAGAAGATAATGTT
ATGAGGTTAACCCTTTTAAAAGCCCCCATTTATCCTGATAGAACTAGTGATAGAGAGGAACACACTTTCACATATTCTAT
TTTTACTCATGATGGTAATAGACAGACAGGTGGTCTTGAAGAGGCTGCCTATGATCTTAATTATCCTTTAATCCTGGAGC
AGGAAAGACGGTTAAAGGTTAAAAAGCCTGTTTTAACAATTAATGTCAAGAGTTTAAAATGCCAGGCATTTAAATTAGCA
GAAGATGGTTCGTCAGATATAATTTTAAGATTAGCTGAGGTTTATGGTTCTCATGGAAAAGCAAAAGTACATTTTAATTT
TAATATTGAAGGCGTAAGTGTATGTAATATTCTAGAAGAAGAGCAAACATCATTGCAGGTTAATGATAACACAGTTACAA
TGGATTTTTCTCCTTACCAAATTATATCTTTAAGAGTTAAAAGGAAGTTGTAA

Upstream 100 bases:

>100_bases
TCGTTCAAGACCAGATGATGACAGAAATACTGATACCATTAACATTAAAGGCTGTTTACAATATTTTCGAACACCTGAAC
TAGTTTTAATAGATGAAAAA

Downstream 100 bases:

>100_bases
GAGAATCTCTTTGGTCGGGGCAACCTGGCCAAAGAGATTTTTTGTTTATGAAATTATGTGAATGCAAAGCATGGATATTC
AACCCTATAGAAAAGGATGG

Product: alpha-mannosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 870; Mature: 870

Protein sequence:

>870_residues
MLSLYYDLKAIYDAAYAESMDESIKNYLQYHLQQLIKEFPLYGCSREEMVMAIPKIKEYINNKIYKGHEHFGKNGKIALV
AHSHLDVAYHWTAKQAIQKNARTTLIQLRLMEEYPDFKYAHSQAWTYEKLEKYYPELFAQVKERIKSGQWEIVGGMYIEP
DCNLISAESFVRQIVYGKYYFKQKFGIDVDNCWLPDVFGNSPIMPQILKSGGLEYFVTHKLSVWNDTNKFPHNVFLWKGL
DGTTVNACIPPIHFVTWMDTEETINNWNQFQDKNVCDETLQLYGYGDGGSGVTDEMLQLYERQQKLPGIPEQRLTTAKEY
LHRIFKDTKDFAVWDGDLYLEMHRGTYTSKAKLKKYNRQGEFLAQEVETLCTACDIYTGDFKVQNKLKNIWKKLLVNQFH
DILPGSHTQPVYKEAIENYEEMFTAFNNLKEKALKKITSPGDEIDYVAFNAFSDVRNKVAYIDANNWDIKYNALKDDEGN
IYPVQKQIKADGSIQYAVKIPDIPGFSLKQFKATSTDKISSSMKVSQTEMENDYYILKLESSGKIVSLYDKVREKYVNTR
NEVLNKWQMFEDKPGALNAWDIVETYKNQEINLPDWENITVIEDGPVSIALRMERKFSNSKAVQVIRMFDNKPQIDFDTW
VDWQEEEKLLKVAFPVNVRSRTYSTDTSAGGFERMNHKNTGWEQGQFEVPCHKWVDISEGLFGVSLMNDCKYGCDVEDNV
MRLTLLKAPIYPDRTSDREEHTFTYSIFTHDGNRQTGGLEEAAYDLNYPLILEQERRLKVKKPVLTINVKSLKCQAFKLA
EDGSSDIILRLAEVYGSHGKAKVHFNFNIEGVSVCNILEEEQTSLQVNDNTVTMDFSPYQIISLRVKRKL

Sequences:

>Translated_870_residues
MLSLYYDLKAIYDAAYAESMDESIKNYLQYHLQQLIKEFPLYGCSREEMVMAIPKIKEYINNKIYKGHEHFGKNGKIALV
AHSHLDVAYHWTAKQAIQKNARTTLIQLRLMEEYPDFKYAHSQAWTYEKLEKYYPELFAQVKERIKSGQWEIVGGMYIEP
DCNLISAESFVRQIVYGKYYFKQKFGIDVDNCWLPDVFGNSPIMPQILKSGGLEYFVTHKLSVWNDTNKFPHNVFLWKGL
DGTTVNACIPPIHFVTWMDTEETINNWNQFQDKNVCDETLQLYGYGDGGSGVTDEMLQLYERQQKLPGIPEQRLTTAKEY
LHRIFKDTKDFAVWDGDLYLEMHRGTYTSKAKLKKYNRQGEFLAQEVETLCTACDIYTGDFKVQNKLKNIWKKLLVNQFH
DILPGSHTQPVYKEAIENYEEMFTAFNNLKEKALKKITSPGDEIDYVAFNAFSDVRNKVAYIDANNWDIKYNALKDDEGN
IYPVQKQIKADGSIQYAVKIPDIPGFSLKQFKATSTDKISSSMKVSQTEMENDYYILKLESSGKIVSLYDKVREKYVNTR
NEVLNKWQMFEDKPGALNAWDIVETYKNQEINLPDWENITVIEDGPVSIALRMERKFSNSKAVQVIRMFDNKPQIDFDTW
VDWQEEEKLLKVAFPVNVRSRTYSTDTSAGGFERMNHKNTGWEQGQFEVPCHKWVDISEGLFGVSLMNDCKYGCDVEDNV
MRLTLLKAPIYPDRTSDREEHTFTYSIFTHDGNRQTGGLEEAAYDLNYPLILEQERRLKVKKPVLTINVKSLKCQAFKLA
EDGSSDIILRLAEVYGSHGKAKVHFNFNIEGVSVCNILEEEQTSLQVNDNTVTMDFSPYQIISLRVKRKL
>Mature_870_residues
MLSLYYDLKAIYDAAYAESMDESIKNYLQYHLQQLIKEFPLYGCSREEMVMAIPKIKEYINNKIYKGHEHFGKNGKIALV
AHSHLDVAYHWTAKQAIQKNARTTLIQLRLMEEYPDFKYAHSQAWTYEKLEKYYPELFAQVKERIKSGQWEIVGGMYIEP
DCNLISAESFVRQIVYGKYYFKQKFGIDVDNCWLPDVFGNSPIMPQILKSGGLEYFVTHKLSVWNDTNKFPHNVFLWKGL
DGTTVNACIPPIHFVTWMDTEETINNWNQFQDKNVCDETLQLYGYGDGGSGVTDEMLQLYERQQKLPGIPEQRLTTAKEY
LHRIFKDTKDFAVWDGDLYLEMHRGTYTSKAKLKKYNRQGEFLAQEVETLCTACDIYTGDFKVQNKLKNIWKKLLVNQFH
DILPGSHTQPVYKEAIENYEEMFTAFNNLKEKALKKITSPGDEIDYVAFNAFSDVRNKVAYIDANNWDIKYNALKDDEGN
IYPVQKQIKADGSIQYAVKIPDIPGFSLKQFKATSTDKISSSMKVSQTEMENDYYILKLESSGKIVSLYDKVREKYVNTR
NEVLNKWQMFEDKPGALNAWDIVETYKNQEINLPDWENITVIEDGPVSIALRMERKFSNSKAVQVIRMFDNKPQIDFDTW
VDWQEEEKLLKVAFPVNVRSRTYSTDTSAGGFERMNHKNTGWEQGQFEVPCHKWVDISEGLFGVSLMNDCKYGCDVEDNV
MRLTLLKAPIYPDRTSDREEHTFTYSIFTHDGNRQTGGLEEAAYDLNYPLILEQERRLKVKKPVLTINVKSLKCQAFKLA
EDGSSDIILRLAEVYGSHGKAKVHFNFNIEGVSVCNILEEEQTSLQVNDNTVTMDFSPYQIISLRVKRKL

Specific function: May hydrolyze mannosyl-D-glycerate to mannose-6- phosphate and glycerate [H]

COG id: COG0383

COG function: function code G; Alpha-mannosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 38 family [H]

Homologues:

Organism=Homo sapiens, GI46852164, Length=806, Percent_Identity=31.7617866004963, Blast_Score=375, Evalue=1e-104,
Organism=Escherichia coli, GI1786952, Length=724, Percent_Identity=23.2044198895028, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6321282, Length=375, Percent_Identity=34.6666666666667, Blast_Score=185, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR011330
- InterPro:   IPR011682
- InterPro:   IPR015341
- InterPro:   IPR000602 [H]

Pfam domain/function: PF09261 Alpha-mann_mid; PF01074 Glyco_hydro_38; PF07748 Glyco_hydro_38C [H]

EC number: 3.2.1.24

Molecular weight: Translated: 100968; Mature: 100968

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLYYDLKAIYDAAYAESMDESIKNYLQYHLQQLIKEFPLYGCSREEMVMAIPKIKEYI
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NNKIYKGHEHFGKNGKIALVAHSHLDVAYHWTAKQAIQKNARTTLIQLRLMEEYPDFKYA
CCCCCCCHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHHCCHHEEEEEEEHHHCCCCCCC
HSQAWTYEKLEKYYPELFAQVKERIKSGQWEIVGGMYIEPDCNLISAESFVRQIVYGKYY
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECEEECCCCCEECHHHHHHHHHHHHHH
FKQKFGIDVDNCWLPDVFGNSPIMPQILKSGGLEYFVTHKLSVWNDTNKFPHNVFLWKGL
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEEEEECCCCCCCCCEEEEEECC
DGTTVNACIPPIHFVTWMDTEETINNWNQFQDKNVCDETLQLYGYGDGGSGVTDEMLQLY
CCCEECCCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHEEEEECCCCCCHHHHHHHHH
ERQQKLPGIPEQRLTTAKEYLHRIFKDTKDFAVWDGDLYLEMHRGTYTSKAKLKKYNRQG
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEECCCCCCHHHHHHHCCCH
EFLAQEVETLCTACDIYTGDFKVQNKLKNIWKKLLVNQFHDILPGSHTQPVYKEAIENYE
HHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
EMFTAFNNLKEKALKKITSPGDEIDYVAFNAFSDVRNKVAYIDANNWDIKYNALKDDEGN
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCEEEEEECCCCEEEEEEEECCCCC
IYPVQKQIKADGSIQYAVKIPDIPGFSLKQFKATSTDKISSSMKVSQTEMENDYYILKLE
EEECHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCHHHHCCCEEHHHHCCCCEEEEEEC
SSGKIVSLYDKVREKYVNTRNEVLNKWQMFEDKPGALNAWDIVETYKNQEINLPDWENIT
CCCCEEHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCEE
VIEDGPVSIALRMERKFSNSKAVQVIRMFDNKPQIDFDTWVDWQEEEKLLKVAFPVNVRS
EEECCCEEEEEEEEHHCCCCHHEEEEEECCCCCCCCHHHCCCCCCCCCEEEEEECCEECC
RTYSTDTSAGGFERMNHKNTGWEQGQFEVPCHKWVDISEGLFGVSLMNDCKYGCDVEDNV
CEECCCCCCCCHHHCCCCCCCCCCCEEECCCHHCCCCCCCCEEEHHHHCCCCCCCCCCCE
MRLTLLKAPIYPDRTSDREEHTFTYSIFTHDGNRQTGGLEEAAYDLNYPLILEQERRLKV
EEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHCCCCCEEECCCCCCEE
KKPVLTINVKSLKCQAFKLAEDGSSDIILRLAEVYGSHGKAKVHFNFNIEGVSVCNILEE
CCCEEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHH
EQTSLQVNDNTVTMDFSPYQIISLRVKRKL
CCCEEEECCCEEEEECCCEEEEEEEEECCC
>Mature Secondary Structure
MLSLYYDLKAIYDAAYAESMDESIKNYLQYHLQQLIKEFPLYGCSREEMVMAIPKIKEYI
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NNKIYKGHEHFGKNGKIALVAHSHLDVAYHWTAKQAIQKNARTTLIQLRLMEEYPDFKYA
CCCCCCCHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHHCCHHEEEEEEEHHHCCCCCCC
HSQAWTYEKLEKYYPELFAQVKERIKSGQWEIVGGMYIEPDCNLISAESFVRQIVYGKYY
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECEEECCCCCEECHHHHHHHHHHHHHH
FKQKFGIDVDNCWLPDVFGNSPIMPQILKSGGLEYFVTHKLSVWNDTNKFPHNVFLWKGL
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEEEEECCCCCCCCCEEEEEECC
DGTTVNACIPPIHFVTWMDTEETINNWNQFQDKNVCDETLQLYGYGDGGSGVTDEMLQLY
CCCEECCCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHEEEEECCCCCCHHHHHHHHH
ERQQKLPGIPEQRLTTAKEYLHRIFKDTKDFAVWDGDLYLEMHRGTYTSKAKLKKYNRQG
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEECCCCCCHHHHHHHCCCH
EFLAQEVETLCTACDIYTGDFKVQNKLKNIWKKLLVNQFHDILPGSHTQPVYKEAIENYE
HHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
EMFTAFNNLKEKALKKITSPGDEIDYVAFNAFSDVRNKVAYIDANNWDIKYNALKDDEGN
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCEEEEEECCCCEEEEEEEECCCCC
IYPVQKQIKADGSIQYAVKIPDIPGFSLKQFKATSTDKISSSMKVSQTEMENDYYILKLE
EEECHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCHHHHCCCEEHHHHCCCCEEEEEEC
SSGKIVSLYDKVREKYVNTRNEVLNKWQMFEDKPGALNAWDIVETYKNQEINLPDWENIT
CCCCEEHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCEE
VIEDGPVSIALRMERKFSNSKAVQVIRMFDNKPQIDFDTWVDWQEEEKLLKVAFPVNVRS
EEECCCEEEEEEEEHHCCCCHHEEEEEECCCCCCCCHHHCCCCCCCCCEEEEEECCEECC
RTYSTDTSAGGFERMNHKNTGWEQGQFEVPCHKWVDISEGLFGVSLMNDCKYGCDVEDNV
CEECCCCCCCCHHHCCCCCCCCCCCEEECCCHHCCCCCCCCEEEHHHHCCCCCCCCCCCE
MRLTLLKAPIYPDRTSDREEHTFTYSIFTHDGNRQTGGLEEAAYDLNYPLILEQERRLKV
EEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHCCCCCEEECCCCCCEE
KKPVLTINVKSLKCQAFKLAEDGSSDIILRLAEVYGSHGKAKVHFNFNIEGVSVCNILEE
CCCEEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHH
EQTSLQVNDNTVTMDFSPYQIISLRVKRKL
CCCEEEECCCEEEEECCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9063979 [H]