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The map label for this gene is arsC [H]

Identifier: 220932303

GI number: 220932303

Start: 1563313

End: 1563720

Strand: Reverse

Name: arsC [H]

Synonym: Hore_14670

Alternate gene names: 220932303

Gene position: 1563720-1563313 (Counterclockwise)

Preceding gene: 220932304

Following gene: 220932302

Centisome position: 60.65

GC content: 41.91

Gene sequence:

>408_bases
ATGAAAAACAAAACTAAAGTTGCTTTTGTATGTGTAGGTAATTCATGCCGCAGCCAGATGGCAGAGGGGTTTGCCAAACA
TCTGGCCTCTGATTTACTGGAGGTATATAGTGCCGGGACCAGGCCCGCCCCCAGGGTTAATCCCAATGCAGTAGAGGTTA
TGTCAGAGGTAGGGATTGATATCAGTAATCAGCATCCTAAACTGCTTGAAGATATACCTTCTGAACTGGATGTTTTAATA
ACCATGGGATGTAATGTCCAGTGTCCCTTTATTCCCTGTAAGTTTAGAGAAGACTGGGGGCTTGATGATCCCGATGGGAA
CCCTATTGAGGAGTTCAGAAAGACCAGGGATATAATTAAAGAAAAAGTGGAAAAGTTAATTGAGAAAGTAAAAAATGGTG
AGTTATAA

Upstream 100 bases:

>100_bases
GTTGGTGTTCTTGTTGAGGTACCGGTAATGTTGGCCCTGGTTGCTATTGCTAATCGTACTAGACACTTATTTAAAAATAG
TGAATAAGGGAGAGGTTATT

Downstream 100 bases:

>100_bases
TATTTTAATGTTGGTGCTATATAAAATTCAGTAACTATGTATTAAAGTAATTCATGACCAGTATAAACAATAAGACCACC
GGAGTAAGTCCGGTGGTTGT

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MKNKTKVAFVCVGNSCRSQMAEGFAKHLASDLLEVYSAGTRPAPRVNPNAVEVMSEVGIDISNQHPKLLEDIPSELDVLI
TMGCNVQCPFIPCKFREDWGLDDPDGNPIEEFRKTRDIIKEKVEKLIEKVKNGEL

Sequences:

>Translated_135_residues
MKNKTKVAFVCVGNSCRSQMAEGFAKHLASDLLEVYSAGTRPAPRVNPNAVEVMSEVGIDISNQHPKLLEDIPSELDVLI
TMGCNVQCPFIPCKFREDWGLDDPDGNPIEEFRKTRDIIKEKVEKLIEKVKNGEL
>Mature_135_residues
MKNKTKVAFVCVGNSCRSQMAEGFAKHLASDLLEVYSAGTRPAPRVNPNAVEVMSEVGIDISNQHPKLLEDIPSELDVLI
TMGCNVQCPFIPCKFREDWGLDDPDGNPIEEFRKTRDIIKEKVEKLIEKVKNGEL

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15087; Mature: 15087

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKTKVAFVCVGNSCRSQMAEGFAKHLASDLLEVYSAGTRPAPRVNPNAVEVMSEVGID
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
ISNQHPKLLEDIPSELDVLITMGCNVQCPFIPCKFREDWGLDDPDGNPIEEFRKTRDIIK
CCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
EKVEKLIEKVKNGEL
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNKTKVAFVCVGNSCRSQMAEGFAKHLASDLLEVYSAGTRPAPRVNPNAVEVMSEVGID
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
ISNQHPKLLEDIPSELDVLITMGCNVQCPFIPCKFREDWGLDDPDGNPIEEFRKTRDIIK
CCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
EKVEKLIEKVKNGEL
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA