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The map label for this gene is mreC [H]

Identifier: 220932259

GI number: 220932259

Start: 1510922

End: 1511749

Strand: Reverse

Name: mreC [H]

Synonym: Hore_14230

Alternate gene names: 220932259

Gene position: 1511749-1510922 (Counterclockwise)

Preceding gene: 220932260

Following gene: 220932258

Centisome position: 58.64

GC content: 39.73

Gene sequence:

>828_bases
TTGAATAAAAGGACCTTTAGTATAAGTATATCTATTATACTGGTTTTATTTGTTACCTCTTTAGGGATTATAAATTTTAC
CGGGGTTGATATACCATACCTGAACTGGCTTCAAGTGGGGACCCATAATCTTATAAGTCCCATAGTTAACTATATAACTG
GCATCTGTGATTCTATACAAGAATACTGGAATGGGATCATGAATGTTAAGCAACTGATTAATGAGAATAAGGGCCTTGAA
AAGAAAGTAGCTAATCTTGAACGGCAGTTACTTGTACTTAAATTTATGGCCCGTGAAAACCAGAGGCTGAGGGAGCTTTT
ATCCTTTAAAGAATTTGTTCCCTATAAAACACTTGGGGCCGGGGTTATTGGTTACAGTCCCTCACCCTGGAAGGAAAAGA
TTATAATAAACCGGGGTTCCAGGGATGGCATTAAACCCAATATGCCCGTTATTTCGTATAATGGTATTCTGGTGGGGAGG
GTGGATTATGTTGCCACTAACTCCTCCCAGGTATTATTGGTCAGTTCCCCTGAATTTGTTGTTGGGGGAATCGTTCAGCG
CCCTGAATCAAGGGCCATCGGACTGGTTAAAGGCCAGCTCAATGAAGAGGGTATAAACTTAATGGACAACCTTTCCTGGG
ATGCCGACATTAAAAAAGGTGATTTAATCTTAACTTCAGGTTTATCCAACAGGTATCCCAAGGGAATTCCGATTGGTGAA
GTTATTAAGGTAGAACCTGATAACTTTGGTCTTTCCCAGAAGGCCAGGGTTGAACTGTTTTTAAATTTGCATACTATTGA
AGAAGTACTCGTTATCACTGATTTTTAG

Upstream 100 bases:

>100_bases
TGACTGTGTAGTTAAAGGGACCGGGGTTGCCCTGGAAGAGCTGGAATCTCTGAAGCGTGTCTTAATCACCCCGAAAAAAA
TATCTTAGGGGGAGGTTTTA

Downstream 100 bases:

>100_bases
GGGGGAGGCAATTGAAAAAAATAGTATGGTATGTCCTGTTATTCACTTTAATAATTATAATTCAGTTGACTATTCCTCCC
CGGACATTACACTTTGATCT

Product: rod shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MNKRTFSISISIILVLFVTSLGIINFTGVDIPYLNWLQVGTHNLISPIVNYITGICDSIQEYWNGIMNVKQLINENKGLE
KKVANLERQLLVLKFMARENQRLRELLSFKEFVPYKTLGAGVIGYSPSPWKEKIIINRGSRDGIKPNMPVISYNGILVGR
VDYVATNSSQVLLVSSPEFVVGGIVQRPESRAIGLVKGQLNEEGINLMDNLSWDADIKKGDLILTSGLSNRYPKGIPIGE
VIKVEPDNFGLSQKARVELFLNLHTIEEVLVITDF

Sequences:

>Translated_275_residues
MNKRTFSISISIILVLFVTSLGIINFTGVDIPYLNWLQVGTHNLISPIVNYITGICDSIQEYWNGIMNVKQLINENKGLE
KKVANLERQLLVLKFMARENQRLRELLSFKEFVPYKTLGAGVIGYSPSPWKEKIIINRGSRDGIKPNMPVISYNGILVGR
VDYVATNSSQVLLVSSPEFVVGGIVQRPESRAIGLVKGQLNEEGINLMDNLSWDADIKKGDLILTSGLSNRYPKGIPIGE
VIKVEPDNFGLSQKARVELFLNLHTIEEVLVITDF
>Mature_275_residues
MNKRTFSISISIILVLFVTSLGIINFTGVDIPYLNWLQVGTHNLISPIVNYITGICDSIQEYWNGIMNVKQLINENKGLE
KKVANLERQLLVLKFMARENQRLRELLSFKEFVPYKTLGAGVIGYSPSPWKEKIIINRGSRDGIKPNMPVISYNGILVGR
VDYVATNSSQVLLVSSPEFVVGGIVQRPESRAIGLVKGQLNEEGINLMDNLSWDADIKKGDLILTSGLSNRYPKGIPIGE
VIKVEPDNFGLSQKARVELFLNLHTIEEVLVITDF

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family [H]

Homologues:

Organism=Escherichia coli, GI1789648, Length=249, Percent_Identity=28.9156626506024, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007221
- InterPro:   IPR005223 [H]

Pfam domain/function: PF04085 MreC [H]

EC number: NA

Molecular weight: Translated: 30744; Mature: 30744

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRTFSISISIILVLFVTSLGIINFTGVDIPYLNWLQVGTHNLISPIVNYITGICDSIQ
CCCEEEEEHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHH
EYWNGIMNVKQLINENKGLEKKVANLERQLLVLKFMARENQRLRELLSFKEFVPYKTLGA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHCC
GVIGYSPSPWKEKIIINRGSRDGIKPNMPVISYNGILVGRVDYVATNSSQVLLVSSPEFV
CEECCCCCCCCCEEEEECCCCCCCCCCCCEEEECCEEEEEEEEEEECCCCEEEEECCCCE
VGGIVQRPESRAIGLVKGQLNEEGINLMDNLSWDADIKKGDLILTSGLSNRYPKGIPIGE
ECHHHCCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
VIKVEPDNFGLSQKARVELFLNLHTIEEVLVITDF
EEEECCCCCCCCCCCEEEEEEEHHHHEEEEEEECC
>Mature Secondary Structure
MNKRTFSISISIILVLFVTSLGIINFTGVDIPYLNWLQVGTHNLISPIVNYITGICDSIQ
CCCEEEEEHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHH
EYWNGIMNVKQLINENKGLEKKVANLERQLLVLKFMARENQRLRELLSFKEFVPYKTLGA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHCC
GVIGYSPSPWKEKIIINRGSRDGIKPNMPVISYNGILVGRVDYVATNSSQVLLVSSPEFV
CEECCCCCCCCCEEEEECCCCCCCCCCCCEEEECCEEEEEEEEEEECCCCEEEEECCCCE
VGGIVQRPESRAIGLVKGQLNEEGINLMDNLSWDADIKKGDLILTSGLSNRYPKGIPIGE
ECHHHCCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
VIKVEPDNFGLSQKARVELFLNLHTIEEVLVITDF
EEEECCCCCCCCCCCEEEEEEEHHHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377 [H]