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The map label for this gene is nudI [H]

Identifier: 220932233

GI number: 220932233

Start: 1487883

End: 1488323

Strand: Reverse

Name: nudI [H]

Synonym: Hore_13970

Alternate gene names: 220932233

Gene position: 1488323-1487883 (Counterclockwise)

Preceding gene: 220932234

Following gene: 220932232

Centisome position: 57.73

GC content: 31.52

Gene sequence:

>441_bases
ATGAGATATCCAGAACCGACTGTTGGAGCAGTAATTTATAATCCTGACAATAAAATATTACTATGTAAATCGGACAAATG
GCATAATAAATATGTAATTCCTGGTGGTCATATTGAACTGGGTGAGACAATGGAAGAAGCATTAATACGAGAAATACGCG
AAGAAACAGGTCTGGAAATATATGATATAGAATTATTAAGTTTAAAAGAAAGTATATACAGTGAAACTTTTCATAAGGAA
AAACATTTTATATTTATTGACTTCAAATGTAGAACAGATCAATATGAAGTAACATTAAATGAAGAAGCCCAGGAATATAA
ATGGGTGGGGCTGGACGAAATCGATAATTATGATCTGGGTGGATTTACCAGACAGTTATTAATGGAATTGCGAAACGAAA
AAGAAGCAAAAAACAGGATAGAGATTTTTTATGGTTATTGA

Upstream 100 bases:

>100_bases
TGCCTTTAGAAAACCAGGCACATATGATATGTTGACCTCTTTCAAGGTTGAAAAACCTTTTATTAGAAAATATGCAAGAA
GATAGAGAGGAGTTAAAATA

Downstream 100 bases:

>100_bases
GTCATTAAATCTGACCTGGGAAGGGGAGAGAAATTAACATGCAGAAAAGATTTATAATTATGGTGATTTTATGTTTTTTG
CTTGCCTTTACTAACCAGTT

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MRYPEPTVGAVIYNPDNKILLCKSDKWHNKYVIPGGHIELGETMEEALIREIREETGLEIYDIELLSLKESIYSETFHKE
KHFIFIDFKCRTDQYEVTLNEEAQEYKWVGLDEIDNYDLGGFTRQLLMELRNEKEAKNRIEIFYGY

Sequences:

>Translated_146_residues
MRYPEPTVGAVIYNPDNKILLCKSDKWHNKYVIPGGHIELGETMEEALIREIREETGLEIYDIELLSLKESIYSETFHKE
KHFIFIDFKCRTDQYEVTLNEEAQEYKWVGLDEIDNYDLGGFTRQLLMELRNEKEAKNRIEIFYGY
>Mature_146_residues
MRYPEPTVGAVIYNPDNKILLCKSDKWHNKYVIPGGHIELGETMEEALIREIREETGLEIYDIELLSLKESIYSETFHKE
KHFIFIDFKCRTDQYEVTLNEEAQEYKWVGLDEIDNYDLGGFTRQLLMELRNEKEAKNRIEIFYGY

Specific function: Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) [H]

COG id: COG1051

COG function: function code F; ADP-ribose pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788585, Length=131, Percent_Identity=34.3511450381679, Blast_Score=70, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.-.- [C]

Molecular weight: Translated: 17408; Mature: 17408

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYPEPTVGAVIYNPDNKILLCKSDKWHNKYVIPGGHIELGETMEEALIREIREETGLEI
CCCCCCCCCEEEECCCCCEEEECCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHCCEE
YDIELLSLKESIYSETFHKEKHFIFIDFKCRTDQYEVTLNEEAQEYKWVGLDEIDNYDLG
EEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCCCEEECCCCCCCCCCCC
GFTRQLLMELRNEKEAKNRIEIFYGY
HHHHHHHHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure
MRYPEPTVGAVIYNPDNKILLCKSDKWHNKYVIPGGHIELGETMEEALIREIREETGLEI
CCCCCCCCCEEEECCCCCEEEECCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHCCEE
YDIELLSLKESIYSETFHKEKHFIFIDFKCRTDQYEVTLNEEAQEYKWVGLDEIDNYDLG
EEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCCCEEECCCCCCCCCCCC
GFTRQLLMELRNEKEAKNRIEIFYGY
HHHHHHHHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA