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The map label for this gene is yqeV [H]

Identifier: 220932113

GI number: 220932113

Start: 1368738

End: 1370054

Strand: Reverse

Name: yqeV [H]

Synonym: Hore_12760

Alternate gene names: 220932113

Gene position: 1370054-1368738 (Counterclockwise)

Preceding gene: 220932114

Following gene: 220932112

Centisome position: 53.14

GC content: 39.1

Gene sequence:

>1317_bases
ATGATGAATACAGTAGCATTCCACACCCTTGGTTGTAAGGTGAATCATTATGAGACAGAAGCCATGATGGGCATATTTGA
AGAGGCCGGTTATAAAGTTGTTGATTTTGATGACCGGGCAGATGTTTATATTATTAATAGTTGTACTGTAACCAATGAAG
CTGCTCGCAAATCAAGACAGCTGGCCCGGAAGGCCAGGCGGAAAAACCCGGAGGCAGTAGTGGCTCTGGTCGGATGTTAT
GCCCAGGTTTCTCCTGATGAGGTTAAGAAAATAGATGCCATTGACCTTGTTCTCGGTTCAGATCGAAGGAAGGACATTGT
TAAATTAGTTGAAGAAGTAAGGACAGGTGGAAAAGAAGTAACTGATGTAAAAGATTTTAAAAAGTTAACCACCTATGAAG
ACCTTAATATAAATAAAGTAAAAGAAACAACCAGGGCTTATATCAAAATTGAAGAGGGCTGTAATCAGTTCTGTAGTTAT
TGTATTATACCCTATGCCCGGGGGCCTGTCAGGAGCAGAAAAGAGGAATCGGTTATCCAGGAAGTTGAGAGACTTGTCCG
GGCCGGGGTTAAGGAAATAGTACTGACAGGTACTCACCTGGGAGCATATGGACTTGATGAAAATAATGATAAAGCTCTGG
TGGAATTAATTCAGAATCTTGTAAAAGTCAAGGGGCTTGCACGAATCAGGTTGAGTTCCCTTGAAGTTACCGAGGTAAAT
GATGATTTAATCAGGATAATGGGCAGTGAAGACAAGGTTTGTCCCCATTTGCATCTTCCATTACAGAGTGGGAGTAATAC
TATTCTAAAAAAGATGAAGAGGCCCTATACGGTTGAGGAGTTTAAGGAGACTGTTGATAAAATAAGGAAAATAATAGAAG
ATATAGCGATAACAACCGATATAATAGTTGGTTTTCCGGGTGAAGGGCAAAAGGAATTTAATGAAAGTTATAATACAGTA
AAGGAATTAGGTTTTAGCAGGCTTCATGTTTTCCCTTTTTCTATTAGGCAGGGTACACCTGCTGCCAGGATGAAAAATCA
GGTTCCCGGTGATGTTAAAAAAGAATATAGCAAAAAGATGCGTGAACTAAATAAAAAATTAATGTTAGAGTATCAAAAAA
GGTTCTGGGGTCACCTCAGGGATGTTATTATTGAGGATAATCGGGACAGCAGGACTAACTTATTGACTGGAGTTACTGGT
AACTATATTAAGGTTATGATTGAAAACGCTGATGATTCATTGCGTGGTAAAATGTGTAAGGTCAGGCTGGATAAAGCCTA
TAACCATGAATATGCCATTGGAAAAGTAATAAAATAA

Upstream 100 bases:

>100_bases
GAATTCCTATAACTTTAGGACCACGTATCTTGAGGACTGAAACTGCTGGACTGGTGGTATTGACCATGCTATTATATGAA
TCAGGTGATTTAGGGGGCTG

Downstream 100 bases:

>100_bases
AGGGTTTTATAATATATTCTAGAAGATATATAAAGATAACTATACAGCCCGGTTAAAATATATTTAGTTAAGTGTATCAT
TATTTTTTTAAATCAATACA

Product: MiaB-like tRNA modifying protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MMNTVAFHTLGCKVNHYETEAMMGIFEEAGYKVVDFDDRADVYIINSCTVTNEAARKSRQLARKARRKNPEAVVALVGCY
AQVSPDEVKKIDAIDLVLGSDRRKDIVKLVEEVRTGGKEVTDVKDFKKLTTYEDLNINKVKETTRAYIKIEEGCNQFCSY
CIIPYARGPVRSRKEESVIQEVERLVRAGVKEIVLTGTHLGAYGLDENNDKALVELIQNLVKVKGLARIRLSSLEVTEVN
DDLIRIMGSEDKVCPHLHLPLQSGSNTILKKMKRPYTVEEFKETVDKIRKIIEDIAITTDIIVGFPGEGQKEFNESYNTV
KELGFSRLHVFPFSIRQGTPAARMKNQVPGDVKKEYSKKMRELNKKLMLEYQKRFWGHLRDVIIEDNRDSRTNLLTGVTG
NYIKVMIENADDSLRGKMCKVRLDKAYNHEYAIGKVIK

Sequences:

>Translated_438_residues
MMNTVAFHTLGCKVNHYETEAMMGIFEEAGYKVVDFDDRADVYIINSCTVTNEAARKSRQLARKARRKNPEAVVALVGCY
AQVSPDEVKKIDAIDLVLGSDRRKDIVKLVEEVRTGGKEVTDVKDFKKLTTYEDLNINKVKETTRAYIKIEEGCNQFCSY
CIIPYARGPVRSRKEESVIQEVERLVRAGVKEIVLTGTHLGAYGLDENNDKALVELIQNLVKVKGLARIRLSSLEVTEVN
DDLIRIMGSEDKVCPHLHLPLQSGSNTILKKMKRPYTVEEFKETVDKIRKIIEDIAITTDIIVGFPGEGQKEFNESYNTV
KELGFSRLHVFPFSIRQGTPAARMKNQVPGDVKKEYSKKMRELNKKLMLEYQKRFWGHLRDVIIEDNRDSRTNLLTGVTG
NYIKVMIENADDSLRGKMCKVRLDKAYNHEYAIGKVIK
>Mature_438_residues
MMNTVAFHTLGCKVNHYETEAMMGIFEEAGYKVVDFDDRADVYIINSCTVTNEAARKSRQLARKARRKNPEAVVALVGCY
AQVSPDEVKKIDAIDLVLGSDRRKDIVKLVEEVRTGGKEVTDVKDFKKLTTYEDLNINKVKETTRAYIKIEEGCNQFCSY
CIIPYARGPVRSRKEESVIQEVERLVRAGVKEIVLTGTHLGAYGLDENNDKALVELIQNLVKVKGLARIRLSSLEVTEVN
DDLIRIMGSEDKVCPHLHLPLQSGSNTILKKMKRPYTVEEFKETVDKIRKIIEDIAITTDIIVGFPGEGQKEFNESYNTV
KELGFSRLHVFPFSIRQGTPAARMKNQVPGDVKKEYSKKMRELNKKLMLEYQKRFWGHLRDVIIEDNRDSRTNLLTGVTG
NYIKVMIENADDSLRGKMCKVRLDKAYNHEYAIGKVIK

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=437, Percent_Identity=29.9771167048055, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI28872784, Length=442, Percent_Identity=26.2443438914027, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI28872782, Length=442, Percent_Identity=26.2443438914027, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI1786882, Length=446, Percent_Identity=29.5964125560538, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI1787057, Length=379, Percent_Identity=31.1345646437995, Blast_Score=165, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17553146, Length=455, Percent_Identity=26.5934065934066, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI71996771, Length=284, Percent_Identity=30.9859154929577, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21356207, Length=438, Percent_Identity=26.2557077625571, Blast_Score=184, Evalue=7e-47,
Organism=Drosophila melanogaster, GI19922432, Length=366, Percent_Identity=31.1475409836066, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 49905; Mature: 49905

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNTVAFHTLGCKVNHYETEAMMGIFEEAGYKVVDFDDRADVYIINSCTVTNEAARKSRQ
CCCCEEEEEECCEECCHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCEECHHHHHHHHH
LARKARRKNPEAVVALVGCYAQVSPDEVKKIDAIDLVLGSDRRKDIVKLVEEVRTGGKEV
HHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCC
TDVKDFKKLTTYEDLNINKVKETTRAYIKIEEGCNQFCSYCIIPYARGPVRSRKEESVIQ
HHHHHHHHHCCCCCCCCHHHHHHHHHHEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
EVERLVRAGVKEIVLTGTHLGAYGLDENNDKALVELIQNLVKVKGLARIRLSSLEVTEVN
HHHHHHHCCHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCEEEEECC
DDLIRIMGSEDKVCPHLHLPLQSGSNTILKKMKRPYTVEEFKETVDKIRKIIEDIAITTD
CHHHEEECCCCCCCCEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IIVGFPGEGQKEFNESYNTVKELGFSRLHVFPFSIRQGTPAARMKNQVPGDVKKEYSKKM
EEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHH
RELNKKLMLEYQKRFWGHLRDVIIEDNRDSRTNLLTGVTGNYIKVMIENADDSLRGKMCK
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHEEECCCCCEEEEEEECCCCHHHCCHHE
VRLDKAYNHEYAIGKVIK
EEECHHCCCCHHHHCCCC
>Mature Secondary Structure
MMNTVAFHTLGCKVNHYETEAMMGIFEEAGYKVVDFDDRADVYIINSCTVTNEAARKSRQ
CCCCEEEEEECCEECCHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCEECHHHHHHHHH
LARKARRKNPEAVVALVGCYAQVSPDEVKKIDAIDLVLGSDRRKDIVKLVEEVRTGGKEV
HHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCC
TDVKDFKKLTTYEDLNINKVKETTRAYIKIEEGCNQFCSYCIIPYARGPVRSRKEESVIQ
HHHHHHHHHCCCCCCCCHHHHHHHHHHEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
EVERLVRAGVKEIVLTGTHLGAYGLDENNDKALVELIQNLVKVKGLARIRLSSLEVTEVN
HHHHHHHCCHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCEEEEECC
DDLIRIMGSEDKVCPHLHLPLQSGSNTILKKMKRPYTVEEFKETVDKIRKIIEDIAITTD
CHHHEEECCCCCCCCEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IIVGFPGEGQKEFNESYNTVKELGFSRLHVFPFSIRQGTPAARMKNQVPGDVKKEYSKKM
EEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHH
RELNKKLMLEYQKRFWGHLRDVIIEDNRDSRTNLLTGVTGNYIKVMIENADDSLRGKMCK
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHEEECCCCCEEEEEEECCCCHHHCCHHE
VRLDKAYNHEYAIGKVIK
EEECHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]