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The map label for this gene is cdd [H]

Identifier: 220932089

GI number: 220932089

Start: 1345878

End: 1346279

Strand: Reverse

Name: cdd [H]

Synonym: Hore_12520

Alternate gene names: 220932089

Gene position: 1346279-1345878 (Counterclockwise)

Preceding gene: 220932090

Following gene: 220932088

Centisome position: 52.22

GC content: 42.79

Gene sequence:

>402_bases
TTGGATAAAACAATTAAAACATTAATTAAGAAAGCAAGAGAAGCCCGGGAAAAATCCTATAGTCCCTATTCTAATTTTGC
AACCGGTGCTGCTGTTTTAACTAAAGAGGGCAAAATATTTACGGGTTGTAATATAGAAAACGCATCCTATGGTTTGACTA
ACTGTGCGGAAAGGACGGCTATATTCAAGGCTGTTTCTGAGGGGTATACTGAATTTGAGGCCCTCGCTGTAGTGGCTGAT
ACCACAAGACCGGTCCCGCCCTGTGGAGCCTGTCGTCAGGTTATTAGAGAATTTTCTCCTGATATGAAGGTGATCATGGG
TAATTTGTCAGGAAATACTGTAGAAACAACCGCTAAAGAACTCCTTCCGGGTGCCTTTAACAGGGGGGATCTGGATTCAT
GA

Upstream 100 bases:

>100_bases
TTATAATAACAATGGTGAACAAGTATCCTTTAACCCCGGTCAAACCTGGATAATAATAGTACCGGAGACCACCTATGTAG
ATTATGAGGAGTGATTAAAT

Downstream 100 bases:

>100_bases
GCTATAAATCCGGTTTTGTTTCTGTAATCGGGAGACCGAATGTGGGAAAATCGACCCTGATCAATAATTTAATTGGGCAG
AAAGTTGTTATCACATCTCC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MDKTIKTLIKKAREAREKSYSPYSNFATGAAVLTKEGKIFTGCNIENASYGLTNCAERTAIFKAVSEGYTEFEALAVVAD
TTRPVPPCGACRQVIREFSPDMKVIMGNLSGNTVETTAKELLPGAFNRGDLDS

Sequences:

>Translated_133_residues
MDKTIKTLIKKAREAREKSYSPYSNFATGAAVLTKEGKIFTGCNIENASYGLTNCAERTAIFKAVSEGYTEFEALAVVAD
TTRPVPPCGACRQVIREFSPDMKVIMGNLSGNTVETTAKELLPGAFNRGDLDS
>Mature_133_residues
MDKTIKTLIKKAREAREKSYSPYSNFATGAAVLTKEGKIFTGCNIENASYGLTNCAERTAIFKAVSEGYTEFEALAVVAD
TTRPVPPCGACRQVIREFSPDMKVIMGNLSGNTVETTAKELLPGAFNRGDLDS

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=131, Percent_Identity=50.381679389313, Blast_Score=137, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17540514, Length=127, Percent_Identity=51.1811023622047, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17551074, Length=128, Percent_Identity=47.65625, Blast_Score=115, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6323274, Length=135, Percent_Identity=40, Blast_Score=98, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24582741, Length=133, Percent_Identity=45.1127819548872, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI19920920, Length=101, Percent_Identity=53.4653465346535, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24582744, Length=140, Percent_Identity=38.5714285714286, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14378; Mature: 14378

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTIKTLIKKAREAREKSYSPYSNFATGAAVLTKEGKIFTGCNIENASYGLTNCAERTA
CCHHHHHHHHHHHHHHHHCCCCCCHHCCCHHEEECCCCEEECCCCCCCCCCHHHHHHHHH
IFKAVSEGYTEFEALAVVADTTRPVPPCGACRQVIREFSPDMKVIMGNLSGNTVETTAKE
HHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
LLPGAFNRGDLDS
HCCCCCCCCCCCC
>Mature Secondary Structure
MDKTIKTLIKKAREAREKSYSPYSNFATGAAVLTKEGKIFTGCNIENASYGLTNCAERTA
CCHHHHHHHHHHHHHHHHCCCCCCHHCCCHHEEECCCCEEECCCCCCCCCCHHHHHHHHH
IFKAVSEGYTEFEALAVVADTTRPVPPCGACRQVIREFSPDMKVIMGNLSGNTVETTAKE
HHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
LLPGAFNRGDLDS
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]