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The map label for this gene is ubiB [C]

Identifier: 220932060

GI number: 220932060

Start: 1317494

End: 1319173

Strand: Reverse

Name: ubiB [C]

Synonym: Hore_12230

Alternate gene names: 220932060

Gene position: 1319173-1317494 (Counterclockwise)

Preceding gene: 220932061

Following gene: 220932059

Centisome position: 51.17

GC content: 36.31

Gene sequence:

>1680_bases
ATGAAGCTTAATATTTCCAGACAATACCGCCATCTAAAGAGGTACCGTCAAATAGCACAGGTGCTGGTAAAAAATGGCCT
CGGTTTTTTATTAGAACATCTTGACTTGACCAAATATTTACCGGTTAAGCACAGGGTCAATAAAGAAGAGATTAAAGCTG
ACAGGTTTAGCCTGGCCCGGCGGTTAAGGGCGGTATTACAGGAGCTTGGTCCTACTTTTATTAAATTCGGGCAATTAATG
AGTACCAGACCTGATATTCTACCTCCGGTCTATATACAGGAGTTGAGAAAACTACAGGATAAGGTCACTCCATTACCTTT
TGAAGATATTGAAAAGGTCCTGATCCAGGAATTGGGTGAGAGTTACAGAGAATTATTTAAAGATCTGGAAGAAACTCCCG
AAGCTGCTGCTTCCATTGCCCAGACCCACCGGGCCACATTACATGATGGCTCTGATGTTATTTTAAAGATTAGAAGGCCG
GGTATTGAAAAGACAATAAAGGTTGACCTTGAAATTTTACATAATCTTGCTTCTATTATAGATGAAAGGGGATTGATTTT
ACAATTTATTAAGGCTACATCCCTGGTAGAAGAATTCAGTAATACCCTCAAAAAAGAACTGAACTTTCAAATTGAAGTTG
CTAATGTGACAAGATTTAAGAATAATTTTAAAGATCATAAATATATACTGGCCCCTGATGTTTATGAAAGGTTATCTACA
AAAAGGCTAATAACTATGGAGAGGATAAAAGGGAAAAAATTAAGTCAGGTGGTCAAAGGTGAAGGCCTTGGGCAGGTTAA
CAGGGGATTTCTGGCCAGGCTCGGAGCTAAATCGTTGATGAAACAGGTCCTGCTGGATGGCTTTTTTCATGCTGATCCTC
ATCCAGGTAATATTATTGTAGTTGGATCAGATAAACTGGCCTATATTGATTTTGGGATGATGGGTCAGTTAACCCAGAGT
GACCGGGACAAATTGAGTCTGTTATTTGTTGCTGTTCTTAAAAAAAATATTGATATGATAGTTGACATTTTGATAGAACT
TGGAATTACCACTAAATCAGTAAATATTAGAAAACTCAAACTTGATATACAGGATTTAATAAATAGGTATTATGGCATTG
ATCTGAAAGATATTGAATTCTCGGTGGTTATTGAAGATTTACAGAAAATACTTTATAATTATAGTATTAGTTTACCCCAG
GAATTTTTTCTTCTAATCAGGGCTATTAGTGTCAGTGAAGGGGTTGGTTTTATGCTGGACCCTTCACTTAATTTAGCTGA
AGTTGGGAATAGTTTTCTGAGAGAGCTTATGTTAAGTCAATTTAAGTTAGATAATATTGCTGGTAGGATTGTGGACAGGC
TCTGGACTTTCAGGAAATCCACCAGTGGTTTACCGCAAAAGTTTAGTAATATAATTGAAAAGATTATAGATGATGAGGTT
ACTATAAGGTTTAAACATATTAACCTGGAAGGATTGATTAATAAAATTGACATTATTTCTAACCGGCTTTCTGTAAGCCT
GATAATTTCAGCTCTGGTTATTGGTTCTTCTATGATAATTCAGACTGAGATGAAACCACTGGTTTTTGGAATACCATTTC
TTGGCTTTGCCGGGTATTCTATAGCAGGAATTATGGGTATCTGGTTAATTATAGCTATTTTCAGATCTGGTAGATTTTAA

Upstream 100 bases:

>100_bases
AGCCGGCTTCGTGACCCGGAGTGAATTAAAAGAACTGGAAAATGAAATCTTAAAACTTAAACAGGAGCTTAAAGAACTGA
AAAACAAGGGAGATTAAAGT

Downstream 100 bases:

>100_bases
TAAATGGGGGCTGATAAAATGCAGGCTAATCTTATCCTTGGGTTGATTTTTGCCCTGTTGATTGCTATCTTTTCTATACA
GAATGCTCAGTCGGTATCCC

Product: 2-octaprenylphenol hydroxylase

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MKLNISRQYRHLKRYRQIAQVLVKNGLGFLLEHLDLTKYLPVKHRVNKEEIKADRFSLARRLRAVLQELGPTFIKFGQLM
STRPDILPPVYIQELRKLQDKVTPLPFEDIEKVLIQELGESYRELFKDLEETPEAAASIAQTHRATLHDGSDVILKIRRP
GIEKTIKVDLEILHNLASIIDERGLILQFIKATSLVEEFSNTLKKELNFQIEVANVTRFKNNFKDHKYILAPDVYERLST
KRLITMERIKGKKLSQVVKGEGLGQVNRGFLARLGAKSLMKQVLLDGFFHADPHPGNIIVVGSDKLAYIDFGMMGQLTQS
DRDKLSLLFVAVLKKNIDMIVDILIELGITTKSVNIRKLKLDIQDLINRYYGIDLKDIEFSVVIEDLQKILYNYSISLPQ
EFFLLIRAISVSEGVGFMLDPSLNLAEVGNSFLRELMLSQFKLDNIAGRIVDRLWTFRKSTSGLPQKFSNIIEKIIDDEV
TIRFKHINLEGLINKIDIISNRLSVSLIISALVIGSSMIIQTEMKPLVFGIPFLGFAGYSIAGIMGIWLIIAIFRSGRF

Sequences:

>Translated_559_residues
MKLNISRQYRHLKRYRQIAQVLVKNGLGFLLEHLDLTKYLPVKHRVNKEEIKADRFSLARRLRAVLQELGPTFIKFGQLM
STRPDILPPVYIQELRKLQDKVTPLPFEDIEKVLIQELGESYRELFKDLEETPEAAASIAQTHRATLHDGSDVILKIRRP
GIEKTIKVDLEILHNLASIIDERGLILQFIKATSLVEEFSNTLKKELNFQIEVANVTRFKNNFKDHKYILAPDVYERLST
KRLITMERIKGKKLSQVVKGEGLGQVNRGFLARLGAKSLMKQVLLDGFFHADPHPGNIIVVGSDKLAYIDFGMMGQLTQS
DRDKLSLLFVAVLKKNIDMIVDILIELGITTKSVNIRKLKLDIQDLINRYYGIDLKDIEFSVVIEDLQKILYNYSISLPQ
EFFLLIRAISVSEGVGFMLDPSLNLAEVGNSFLRELMLSQFKLDNIAGRIVDRLWTFRKSTSGLPQKFSNIIEKIIDDEV
TIRFKHINLEGLINKIDIISNRLSVSLIISALVIGSSMIIQTEMKPLVFGIPFLGFAGYSIAGIMGIWLIIAIFRSGRF
>Mature_559_residues
MKLNISRQYRHLKRYRQIAQVLVKNGLGFLLEHLDLTKYLPVKHRVNKEEIKADRFSLARRLRAVLQELGPTFIKFGQLM
STRPDILPPVYIQELRKLQDKVTPLPFEDIEKVLIQELGESYRELFKDLEETPEAAASIAQTHRATLHDGSDVILKIRRP
GIEKTIKVDLEILHNLASIIDERGLILQFIKATSLVEEFSNTLKKELNFQIEVANVTRFKNNFKDHKYILAPDVYERLST
KRLITMERIKGKKLSQVVKGEGLGQVNRGFLARLGAKSLMKQVLLDGFFHADPHPGNIIVVGSDKLAYIDFGMMGQLTQS
DRDKLSLLFVAVLKKNIDMIVDILIELGITTKSVNIRKLKLDIQDLINRYYGIDLKDIEFSVVIEDLQKILYNYSISLPQ
EFFLLIRAISVSEGVGFMLDPSLNLAEVGNSFLRELMLSQFKLDNIAGRIVDRLWTFRKSTSGLPQKFSNIIEKIIDDEV
TIRFKHINLEGLINKIDIISNRLSVSLIISALVIGSSMIIQTEMKPLVFGIPFLGFAGYSIAGIMGIWLIIAIFRSGRF

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=367, Percent_Identity=25.8855585831063, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI40254938, Length=295, Percent_Identity=26.4406779661017, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI34147522, Length=282, Percent_Identity=24.822695035461, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI217035081, Length=237, Percent_Identity=25.3164556962025, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI32261307, Length=336, Percent_Identity=23.5119047619048, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI27363457, Length=350, Percent_Identity=23.1428571428571, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI217416386, Length=318, Percent_Identity=23.8993710691824, Blast_Score=87, Evalue=5e-17,
Organism=Escherichia coli, GI2367309, Length=505, Percent_Identity=29.9009900990099, Blast_Score=205, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17559152, Length=288, Percent_Identity=28.8194444444444, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32565180, Length=280, Percent_Identity=26.0714285714286, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17555620, Length=476, Percent_Identity=21.8487394957983, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321319, Length=243, Percent_Identity=29.2181069958848, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325148, Length=457, Percent_Identity=22.9759299781182, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6323282, Length=249, Percent_Identity=26.9076305220884, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI22024280, Length=271, Percent_Identity=28.4132841328413, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24662575, Length=290, Percent_Identity=27.9310344827586, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI18859849, Length=256, Percent_Identity=26.171875, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 63761; Mature: 63761

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNISRQYRHLKRYRQIAQVLVKNGLGFLLEHLDLTKYLPVKHRVNKEEIKADRFSLAR
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHH
RLRAVLQELGPTFIKFGQLMSTRPDILPPVYIQELRKLQDKVTPLPFEDIEKVLIQELGE
HHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SYRELFKDLEETPEAAASIAQTHRATLHDGSDVILKIRRPGIEKTIKVDLEILHNLASII
HHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
DERGLILQFIKATSLVEEFSNTLKKELNFQIEVANVTRFKNNFKDHKYILAPDVYERLST
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCEEEECCHHHHHHHH
KRLITMERIKGKKLSQVVKGEGLGQVNRGFLARLGAKSLMKQVLLDGFFHADPHPGNIIV
HHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
VGSDKLAYIDFGMMGQLTQSDRDKLSLLFVAVLKKNIDMIVDILIELGITTKSVNIRKLK
ECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
LDIQDLINRYYGIDLKDIEFSVVIEDLQKILYNYSISLPQEFFLLIRAISVSEGVGFMLD
ECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEC
PSLNLAEVGNSFLRELMLSQFKLDNIAGRIVDRLWTFRKSTSGLPQKFSNIIEKIIDDEV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCE
TIRFKHINLEGLINKIDIISNRLSVSLIISALVIGSSMIIQTEMKPLVFGIPFLGFAGYS
EEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCHHHCCCHHHHHHHHH
IAGIMGIWLIIAIFRSGRF
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLNISRQYRHLKRYRQIAQVLVKNGLGFLLEHLDLTKYLPVKHRVNKEEIKADRFSLAR
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHH
RLRAVLQELGPTFIKFGQLMSTRPDILPPVYIQELRKLQDKVTPLPFEDIEKVLIQELGE
HHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SYRELFKDLEETPEAAASIAQTHRATLHDGSDVILKIRRPGIEKTIKVDLEILHNLASII
HHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
DERGLILQFIKATSLVEEFSNTLKKELNFQIEVANVTRFKNNFKDHKYILAPDVYERLST
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCEEEECCHHHHHHHH
KRLITMERIKGKKLSQVVKGEGLGQVNRGFLARLGAKSLMKQVLLDGFFHADPHPGNIIV
HHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
VGSDKLAYIDFGMMGQLTQSDRDKLSLLFVAVLKKNIDMIVDILIELGITTKSVNIRKLK
ECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
LDIQDLINRYYGIDLKDIEFSVVIEDLQKILYNYSISLPQEFFLLIRAISVSEGVGFMLD
ECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEC
PSLNLAEVGNSFLRELMLSQFKLDNIAGRIVDRLWTFRKSTSGLPQKFSNIIEKIIDDEV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCE
TIRFKHINLEGLINKIDIISNRLSVSLIISALVIGSSMIIQTEMKPLVFGIPFLGFAGYS
EEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCHHHCCCHHHHHHHHH
IAGIMGIWLIIAIFRSGRF
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA