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The map label for this gene is exbB [C]

Identifier: 220932018

GI number: 220932018

Start: 1277571

End: 1278221

Strand: Reverse

Name: exbB [C]

Synonym: Hore_11810

Alternate gene names: 220932018

Gene position: 1278221-1277571 (Counterclockwise)

Preceding gene: 220932019

Following gene: 220932017

Centisome position: 49.58

GC content: 38.56

Gene sequence:

>651_bases
TTGAATTTTTCCCAGATCAGTAATTTCATATCTCTTGGAGGACCGATGACTATTCCCCTTATTATTGCATCTATTTTCGG
GGTTGCCGTAATTTTAGAAAAATTGATTTTTTTTGCCAGATACCGTGATAATAGCTTCAGGCTGATTAAAAAAATTGAAT
TGCTTGTCGAAGAAGGTGACATTTTAACAGCCTTAAATGAATTGAAAGGAGAACGGGGGCCAAATGCCAAATTATTGTCA
ACCGCCCTTGCCCACCATAGTGAAGAACCTGGCCGTATTAAAGAAGTCCTCCAGGCGGTAGGTGAAGATGAAATTAAAAA
AATGGAAAAGCACTTACCGATACTTGATGTGATAGCTACAGTTTCCCCCTTACTGGGACTACTTGGAACTGTAATGGGTA
TTATCAGTAGTTTTAATATTATGGGAGCTGCTGCCGGTGCAGCTAACCCTCATCAGATCAGTGCCGGTATTGCTGAAGCC
TTAATTAGTACAGCCCTGGGACTTATAATAGCTATTCCTACTGCTGTTTTCTATTCTTACTTTGCCAATAAGGTTGAAAA
TAAGGCCCATGAAATGAATTTAAGTATGATCGATATTTTAGAGGTGGTTGGAAATAACAGGAGGGAAGATAATGTTAAAA
ACTTCTCTTAA

Upstream 100 bases:

>100_bases
TTATTATTATGGTTACTGTCAAAAATGCAGGAAAAACCTTTTTTACGTCGAATTCTAAGTATAGGAATCATGCTATATTT
ATATAAAGGAGTGGTTTAAC

Downstream 100 bases:

>100_bases
GAAAAAACCATCTATTAATATAATTCCAATGATTGATGTTATCTTCTTTTTACTCGTCTTTTTTATGTTGTTTACAACCT
TTCGCACAACCCCTTACGGT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNFSQISNFISLGGPMTIPLIIASIFGVAVILEKLIFFARYRDNSFRLIKKIELLVEEGDILTALNELKGERGPNAKLLS
TALAHHSEEPGRIKEVLQAVGEDEIKKMEKHLPILDVIATVSPLLGLLGTVMGIISSFNIMGAAAGAANPHQISAGIAEA
LISTALGLIIAIPTAVFYSYFANKVENKAHEMNLSMIDILEVVGNNRREDNVKNFS

Sequences:

>Translated_216_residues
MNFSQISNFISLGGPMTIPLIIASIFGVAVILEKLIFFARYRDNSFRLIKKIELLVEEGDILTALNELKGERGPNAKLLS
TALAHHSEEPGRIKEVLQAVGEDEIKKMEKHLPILDVIATVSPLLGLLGTVMGIISSFNIMGAAAGAANPHQISAGIAEA
LISTALGLIIAIPTAVFYSYFANKVENKAHEMNLSMIDILEVVGNNRREDNVKNFS
>Mature_216_residues
MNFSQISNFISLGGPMTIPLIIASIFGVAVILEKLIFFARYRDNSFRLIKKIELLVEEGDILTALNELKGERGPNAKLLS
TALAHHSEEPGRIKEVLQAVGEDEIKKMEKHLPILDVIATVSPLLGLLGTVMGIISSFNIMGAAAGAANPHQISAGIAEA
LISTALGLIIAIPTAVFYSYFANKVENKAHEMNLSMIDILEVVGNNRREDNVKNFS

Specific function: Involved In The Tonb-Dependent Energy-Dependent Transport Of Various Receptor-Bound Substrates. Protects Exbd From Proteolytic Degradation And Functionally Stabilizes Tonb. [C]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=181, Percent_Identity=33.1491712707182, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1786958, Length=98, Percent_Identity=36.734693877551, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 23410; Mature: 23410

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFSQISNFISLGGPMTIPLIIASIFGVAVILEKLIFFARYRDNSFRLIKKIELLVEEGD
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCH
ILTALNELKGERGPNAKLLSTALAHHSEEPGRIKEVLQAVGEDEIKKMEKHLPILDVIAT
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHHHH
VSPLLGLLGTVMGIISSFNIMGAAAGAANPHQISAGIAEALISTALGLIIAIPTAVFYSY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FANKVENKAHEMNLSMIDILEVVGNNRREDNVKNFS
HHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNFSQISNFISLGGPMTIPLIIASIFGVAVILEKLIFFARYRDNSFRLIKKIELLVEEGD
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCH
ILTALNELKGERGPNAKLLSTALAHHSEEPGRIKEVLQAVGEDEIKKMEKHLPILDVIAT
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHHHH
VSPLLGLLGTVMGIISSFNIMGAAAGAANPHQISAGIAEALISTALGLIIAIPTAVFYSY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FANKVENKAHEMNLSMIDILEVVGNNRREDNVKNFS
HHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]