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The map label for this gene is hflX [H]

Identifier: 220931954

GI number: 220931954

Start: 1208267

End: 1209454

Strand: Reverse

Name: hflX [H]

Synonym: Hore_11140

Alternate gene names: 220931954

Gene position: 1209454-1208267 (Counterclockwise)

Preceding gene: 220931964

Following gene: 220931953

Centisome position: 46.91

GC content: 36.53

Gene sequence:

>1188_bases
GTGGTTGGTCAGGATGAAATAAGCCTTGAAGAACTAAAGCGACTGGCTGATACTGCTGGAGTAAAAGTATTAAAAAAATT
AATGCAGCGTCGTTTTGTTATAAATCCTGCCTTTTATATAGGCAAGGGCAAACTGAAAGAACTAAAACATTTAGTATTTG
AAAATGGTGCAAATCTTGTAATATTTGACAATGAACTAACTCCAGCCCAGTTCAGGAATCTCGAAAATTTCCTGGAAACC
AGAGTTGTTGATAGAACTCAGTTAATTTTGGATATTTTTGCTCAACATGCCCATACCAGAGAAAGTAAACTCCAGGTTGA
ACTCGCCCAGCTTCAATACCTTCTACCGAGACTAACTGGAAAAGGAGAAGAACTATCGAGACTCGGGGGTGGTATTGGTA
CCAGGGGCCCCGGGGAAACAAAGTTAGAAATAGACAGACGTCGTATTGAAAAAAGAATATATAAACTCAAACAGGAATTA
AAGAATGTAAAAAAGAATCGTCAAATCCAGAGAAAATCAAGAAAAGACCCTGTTGTAGCCCTGGTCGGTTATACAAATGC
TGGTAAATCTACCCTGTTAAATACACTAACCAATGCAAATACTGAAGTGGCTGACAAACTATTTGCAACCCTTGATTCTA
CATTAAGAAGGTTAACCCTCCCCTTCGGTAAACAGATTATTATTAGTGATACAGTTGGTTTTATAAAAAAATTACCTCAC
CAACTGGTAGCTTCATTTCAGGCAACCCTGGAAGAAATCAAAGAAGCTGATATCTTACTTCATGTAGTCGACAGTAGTGA
ACCCGAACTTGAAAACCATATTAAGGTTGTCAATGCTGTCTTAAAGGAACTTGGGGTCTTTCATAAAGAAAAAATAATGG
TCCTTAACAAGATTGATCGACTAGAAAAAGGTCAATTACTTGACCTTGGTATAAAATATCCACGTGCTGTGCCTGTATCC
GCTCTATCGGGTAAATGTATAGATAATCTTATGGGAAAAATATGTGAAATTATGTTAAATGAAATGACAACAGTTCATTT
AAAAATTCCTTACCACGAAGCTGGATGGATTAATACAATACATCACCAGGGGTTAGTACTGAAAGAAAAATACGTTAATG
ACTCTATTATTATAAAGGCAACAATTCCCACAGAACTGGCAAACCGGTTAAAAAAATATACCTATTAA

Upstream 100 bases:

>100_bases
AAAATGGTTGGATATAATTGACTTAGAATATAAAAAGGTGGAGGGATAAAATATTACCGTCACTGAAGATTTAAGGGGAA
ATGCATTTACTCTGGCCATT

Downstream 100 bases:

>100_bases
ATAAATTCTCATAAACCCGGTAACCATTAAAATTTTAACTTTACTGGGTATTATTATTTAATCATTTACTCTAGAGAAAA
TTTTTTTTAAAGTGCATTAT

Product: small GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MVGQDEISLEELKRLADTAGVKVLKKLMQRRFVINPAFYIGKGKLKELKHLVFENGANLVIFDNELTPAQFRNLENFLET
RVVDRTQLILDIFAQHAHTRESKLQVELAQLQYLLPRLTGKGEELSRLGGGIGTRGPGETKLEIDRRRIEKRIYKLKQEL
KNVKKNRQIQRKSRKDPVVALVGYTNAGKSTLLNTLTNANTEVADKLFATLDSTLRRLTLPFGKQIIISDTVGFIKKLPH
QLVASFQATLEEIKEADILLHVVDSSEPELENHIKVVNAVLKELGVFHKEKIMVLNKIDRLEKGQLLDLGIKYPRAVPVS
ALSGKCIDNLMGKICEIMLNEMTTVHLKIPYHEAGWINTIHHQGLVLKEKYVNDSIIIKATIPTELANRLKKYTY

Sequences:

>Translated_395_residues
MVGQDEISLEELKRLADTAGVKVLKKLMQRRFVINPAFYIGKGKLKELKHLVFENGANLVIFDNELTPAQFRNLENFLET
RVVDRTQLILDIFAQHAHTRESKLQVELAQLQYLLPRLTGKGEELSRLGGGIGTRGPGETKLEIDRRRIEKRIYKLKQEL
KNVKKNRQIQRKSRKDPVVALVGYTNAGKSTLLNTLTNANTEVADKLFATLDSTLRRLTLPFGKQIIISDTVGFIKKLPH
QLVASFQATLEEIKEADILLHVVDSSEPELENHIKVVNAVLKELGVFHKEKIMVLNKIDRLEKGQLLDLGIKYPRAVPVS
ALSGKCIDNLMGKICEIMLNEMTTVHLKIPYHEAGWINTIHHQGLVLKEKYVNDSIIIKATIPTELANRLKKYTY
>Mature_395_residues
MVGQDEISLEELKRLADTAGVKVLKKLMQRRFVINPAFYIGKGKLKELKHLVFENGANLVIFDNELTPAQFRNLENFLET
RVVDRTQLILDIFAQHAHTRESKLQVELAQLQYLLPRLTGKGEELSRLGGGIGTRGPGETKLEIDRRRIEKRIYKLKQEL
KNVKKNRQIQRKSRKDPVVALVGYTNAGKSTLLNTLTNANTEVADKLFATLDSTLRRLTLPFGKQIIISDTVGFIKKLPH
QLVASFQATLEEIKEADILLHVVDSSEPELENHIKVVNAVLKELGVFHKEKIMVLNKIDRLEKGQLLDLGIKYPRAVPVS
ALSGKCIDNLMGKICEIMLNEMTTVHLKIPYHEAGWINTIHHQGLVLKEKYVNDSIIIKATIPTELANRLKKYTY

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=248, Percent_Identity=33.0645161290323, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI310133118, Length=257, Percent_Identity=33.4630350194552, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI310124269, Length=233, Percent_Identity=34.3347639484979, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI310124267, Length=233, Percent_Identity=34.3347639484979, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI310124171, Length=233, Percent_Identity=34.3347639484979, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI310124169, Length=233, Percent_Identity=34.3347639484979, Blast_Score=125, Evalue=8e-29,
Organism=Escherichia coli, GI1790615, Length=396, Percent_Identity=42.4242424242424, Blast_Score=293, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17561038, Length=330, Percent_Identity=30.3030303030303, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24650079, Length=255, Percent_Identity=36.8627450980392, Blast_Score=118, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 44845; Mature: 44845

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGQDEISLEELKRLADTAGVKVLKKLMQRRFVINPAFYIGKGKLKELKHLVFENGANLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHCCCCEE
IFDNELTPAQFRNLENFLETRVVDRTQLILDIFAQHAHTRESKLQVELAQLQYLLPRLTG
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
KGEELSRLGGGIGTRGPGETKLEIDRRRIEKRIYKLKQELKNVKKNRQIQRKSRKDPVVA
CCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LVGYTNAGKSTLLNTLTNANTEVADKLFATLDSTLRRLTLPFGKQIIISDTVGFIKKLPH
EEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
QLVASFQATLEEIKEADILLHVVDSSEPELENHIKVVNAVLKELGVFHKEKIMVLNKIDR
HHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LEKGQLLDLGIKYPRAVPVSALSGKCIDNLMGKICEIMLNEMTTVHLKIPYHEAGWINTI
HCCCCEEECCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHH
HHQGLVLKEKYVNDSIIIKATIPTELANRLKKYTY
HHCCEEEHHHHCCCEEEEEEECCHHHHHHHHHCCC
>Mature Secondary Structure
MVGQDEISLEELKRLADTAGVKVLKKLMQRRFVINPAFYIGKGKLKELKHLVFENGANLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHCCCCEE
IFDNELTPAQFRNLENFLETRVVDRTQLILDIFAQHAHTRESKLQVELAQLQYLLPRLTG
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
KGEELSRLGGGIGTRGPGETKLEIDRRRIEKRIYKLKQELKNVKKNRQIQRKSRKDPVVA
CCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LVGYTNAGKSTLLNTLTNANTEVADKLFATLDSTLRRLTLPFGKQIIISDTVGFIKKLPH
EEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
QLVASFQATLEEIKEADILLHVVDSSEPELENHIKVVNAVLKELGVFHKEKIMVLNKIDR
HHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LEKGQLLDLGIKYPRAVPVSALSGKCIDNLMGKICEIMLNEMTTVHLKIPYHEAGWINTI
HCCCCEEECCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHH
HHQGLVLKEKYVNDSIIIKATIPTELANRLKKYTY
HHCCEEEHHHHCCCEEEEEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]