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The map label for this gene is ackA

Identifier: 220931864

GI number: 220931864

Start: 1111979

End: 1113175

Strand: Direct

Name: ackA

Synonym: Hore_10210

Alternate gene names: 220931864

Gene position: 1111979-1113175 (Clockwise)

Preceding gene: 220931863

Following gene: 220931865

Centisome position: 43.13

GC content: 39.01

Gene sequence:

>1197_bases
ATGAAAATACTTGTTCTAAATAGTGGTAGCTCTTCATTAAAATATCAGTTATTTGATATGGAAAAGGAAACGGTTATGGC
AAAAGGGGTAGTTCAAAGAATTGGAATTGATAATTCATTTTTAGAACATGAAAACTATAGAGGTGAGGAAACAACAATTG
AAACCGATATACCCGATCATAACCGGGGAATTCAATTGGTTATAGATACCCTTCAGGATGAAAAATACGGTGTCCTCAAT
AACATGGAGGAGATTGATGCTGTTGGCCACCGGGTTGTCCATGGTGGAGAAAAATTTGCTGAATCTACTTTAATTACTGA
TGAAGTAATTAAGCAGATAGAAGAAGTTTCAGAACTTGCCCCCCTTCATAATCCACATAATCTGACAGGTATCCGGGTAT
GTAGCAAATTAATGCCTGGAATTCCTCAGGTAGCTGTTTTTGACACAGCATTTCATCAAACAATGCCCAGGAAAGCTTAT
GTTTATGCCCTTCCCTATGAATATTATGAAAAATATGGGATTAGAAGGTATGGTTTTCACGGAACTTCACACAAATATGT
TGCTGAAAGGGCTGCCCGTTTAATGGACAAGCCCCTTGAAGAACTTAAGATTATAACATGTCATCTGGGGAATGGAGCCA
GTGTGGCTGCAATAGACGCGGGTAAATCTGTTGATACCAGTATGGGATTAACACCGTTAGAAGGTCTAGTAATGGGGACA
AGGTGTGGAGATATAGATCCGGCCATAATCCCTTTTATTATGGATAAAGAAAACCTCGATATTAAGGAAGTGGACAATGT
CCTGAATAAAAAGAGTGGTCTTTATGGGGTTTCCGGTATCAGTAATGATTCCAGGGATGTAGAAGAGGCTTCTAAAGACG
GTAATGAAAGAGCTACAATTGCCCTTGAAATCTTTAAATACAGGGTTAAAAAATATATCGGGGCCTATACTGCAGTCATG
GGGGGAGTAGATGCAGTTGTATTTACTGCTGGAATAGGCGAAAATGCCATTGAAATGAGAGAATCCATTGTTGAAGAACT
GGGCTTTTTGGGTGTCAAACTAGATCGTGACGCCAATAACAACCGGGGTAAAGAAATTGAAATATCTACAAAAGATTCAA
GGACAAAAATCTTTGTTATTCCTACAAATGAGGAATTGGTTATTGCCCGCGATACTGCCCGTATAGTGGAATCTTGA

Upstream 100 bases:

>100_bases
GTCCAGGCCCAGGATAATTAAGTTTGAGGTTATGTTTATTTATGTCGTGATAACGGTATTACCGTAAAATATATCCTTAA
TAAAAAAAGGAGGATTAATT

Downstream 100 bases:

>100_bases
TTTTTACTTGACAAATTAAGGGCAGGTAGTTATAATTAACTTTGGTTTATTACGTGATCCGTCAAAGAGGTGAAACTATG
GAAATTGACCTGTCCCGGTT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MKILVLNSGSSSLKYQLFDMEKETVMAKGVVQRIGIDNSFLEHENYRGEETTIETDIPDHNRGIQLVIDTLQDEKYGVLN
NMEEIDAVGHRVVHGGEKFAESTLITDEVIKQIEEVSELAPLHNPHNLTGIRVCSKLMPGIPQVAVFDTAFHQTMPRKAY
VYALPYEYYEKYGIRRYGFHGTSHKYVAERAARLMDKPLEELKIITCHLGNGASVAAIDAGKSVDTSMGLTPLEGLVMGT
RCGDIDPAIIPFIMDKENLDIKEVDNVLNKKSGLYGVSGISNDSRDVEEASKDGNERATIALEIFKYRVKKYIGAYTAVM
GGVDAVVFTAGIGENAIEMRESIVEELGFLGVKLDRDANNNRGKEIEISTKDSRTKIFVIPTNEELVIARDTARIVES

Sequences:

>Translated_398_residues
MKILVLNSGSSSLKYQLFDMEKETVMAKGVVQRIGIDNSFLEHENYRGEETTIETDIPDHNRGIQLVIDTLQDEKYGVLN
NMEEIDAVGHRVVHGGEKFAESTLITDEVIKQIEEVSELAPLHNPHNLTGIRVCSKLMPGIPQVAVFDTAFHQTMPRKAY
VYALPYEYYEKYGIRRYGFHGTSHKYVAERAARLMDKPLEELKIITCHLGNGASVAAIDAGKSVDTSMGLTPLEGLVMGT
RCGDIDPAIIPFIMDKENLDIKEVDNVLNKKSGLYGVSGISNDSRDVEEASKDGNERATIALEIFKYRVKKYIGAYTAVM
GGVDAVVFTAGIGENAIEMRESIVEELGFLGVKLDRDANNNRGKEIEISTKDSRTKIFVIPTNEELVIARDTARIVES
>Mature_398_residues
MKILVLNSGSSSLKYQLFDMEKETVMAKGVVQRIGIDNSFLEHENYRGEETTIETDIPDHNRGIQLVIDTLQDEKYGVLN
NMEEIDAVGHRVVHGGEKFAESTLITDEVIKQIEEVSELAPLHNPHNLTGIRVCSKLMPGIPQVAVFDTAFHQTMPRKAY
VYALPYEYYEKYGIRRYGFHGTSHKYVAERAARLMDKPLEELKIITCHLGNGASVAAIDAGKSVDTSMGLTPLEGLVMGT
RCGDIDPAIIPFIMDKENLDIKEVDNVLNKKSGLYGVSGISNDSRDVEEASKDGNERATIALEIFKYRVKKYIGAYTAVM
GGVDAVVFTAGIGENAIEMRESIVEELGFLGVKLDRDANNNRGKEIEISTKDSRTKIFVIPTNEELVIARDTARIVES

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=402, Percent_Identity=42.7860696517413, Blast_Score=345, Evalue=2e-96,
Organism=Escherichia coli, GI1788633, Length=400, Percent_Identity=46.25, Blast_Score=345, Evalue=4e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACKA_HALOH (B8CWV8)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508772.1
- GeneID:   7314609
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_10210
- HOGENOM:   HBG285863
- OMA:   SSDFRDV
- ProtClustDB:   CLSK2806355
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 44179; Mature: 44179

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVLNSGSSSLKYQLFDMEKETVMAKGVVQRIGIDNSFLEHENYRGEETTIETDIPDH
CEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEECCCCCC
NRGIQLVIDTLQDEKYGVLNNMEEIDAVGHRVVHGGEKFAESTLITDEVIKQIEEVSELA
CCCEEEEEEECCCCCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
PLHNPHNLTGIRVCSKLMPGIPQVAVFDTAFHQTMPRKAYVYALPYEYYEKYGIRRYGFH
CCCCCCCCHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCEEEEECCHHHHHHCCCEEECCC
GTSHKYVAERAARLMDKPLEELKIITCHLGNGASVAAIDAGKSVDTSMGLTPLEGLVMGT
CCCHHHHHHHHHHHHHCCHHHEEEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHEEEEC
RCGDIDPAIIPFIMDKENLDIKEVDNVLNKKSGLYGVSGISNDSRDVEEASKDGNERATI
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCCCCEEE
ALEIFKYRVKKYIGAYTAVMGGVDAVVFTAGIGENAIEMRESIVEELGFLGVKLDRDANN
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCC
NRGKEIEISTKDSRTKIFVIPTNEELVIARDTARIVES
CCCCEEEEECCCCCEEEEEEECCCCEEEEECHHHHHCC
>Mature Secondary Structure
MKILVLNSGSSSLKYQLFDMEKETVMAKGVVQRIGIDNSFLEHENYRGEETTIETDIPDH
CEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEECCCCCC
NRGIQLVIDTLQDEKYGVLNNMEEIDAVGHRVVHGGEKFAESTLITDEVIKQIEEVSELA
CCCEEEEEEECCCCCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
PLHNPHNLTGIRVCSKLMPGIPQVAVFDTAFHQTMPRKAYVYALPYEYYEKYGIRRYGFH
CCCCCCCCHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCEEEEECCHHHHHHCCCEEECCC
GTSHKYVAERAARLMDKPLEELKIITCHLGNGASVAAIDAGKSVDTSMGLTPLEGLVMGT
CCCHHHHHHHHHHHHHCCHHHEEEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHEEEEC
RCGDIDPAIIPFIMDKENLDIKEVDNVLNKKSGLYGVSGISNDSRDVEEASKDGNERATI
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCCCCEEE
ALEIFKYRVKKYIGAYTAVMGGVDAVVFTAGIGENAIEMRESIVEELGFLGVKLDRDANN
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCC
NRGKEIEISTKDSRTKIFVIPTNEELVIARDTARIVES
CCCCEEEEECCCCCEEEEEEECCCCEEEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA