Click here to switch to the map view.

The map label for this gene is coaD [H]

Identifier: 220931857

GI number: 220931857

Start: 1104688

End: 1105176

Strand: Direct

Name: coaD [H]

Synonym: Hore_10140

Alternate gene names: 220931857

Gene position: 1104688-1105176 (Clockwise)

Preceding gene: 220931856

Following gene: 220931859

Centisome position: 42.85

GC content: 35.99

Gene sequence:

>489_bases
ATGTTAAACAGGGTTGTTTATCCAGGTAGTTTTGATCCAGTAACATATGGACATTTAGATATTATAAAAAGGGCAGCCCA
GATATTTGATGAGGTTATTGTCGCTGTTTTTAGAAATCCCCGGAAAAATCCTTTATTTTCAATGGATGAGAGAGTAAAGT
TATTAAAGGAAGTTACTAAAGAAATAGACAGGGTTCAGGTCGATTGTTTTAATGGTTTGTTGGTTGAATATGCCAGGTCA
AAAAAAGCCAGGGCTGTAATCAGAGGGTTAAGGGCTGTTTCCGATTTTGAAGGAGAGTTTCAGATGGCTTCGATGAATAA
ACAACTGGATAGTGACATTGAAACAGTCTTTTTTATGACAGATACAAAATATGCTTTTTTAAGTTCGAGTGTTGTCAAAG
AAGTGGCCCAGTTTAATGGAAATGTTAAAGGAATGGTTCCTGACGTTGTTGCTAAAGCCCTGGTAGAAAAATATAATTAT
TCACGGTAG

Upstream 100 bases:

>100_bases
TCCCGGAGAAGAAATAATTACACCGGAAGAACTGGACTTAATAACAAACAGGGAATATGGTAAAAGTGGAATAACAATTC
TAAAAAAGTAGGTGGTATAT

Downstream 100 bases:

>100_bases
TGGAAGAATATGACCTCTATACGCTGTAGTAAATACAAAATCATTGATAACATAAAACTTATCATTAAAATTAAAACTAT
AAAACCAAAGCTAATAATAA

Product: pantetheine-phosphate adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MLNRVVYPGSFDPVTYGHLDIIKRAAQIFDEVIVAVFRNPRKNPLFSMDERVKLLKEVTKEIDRVQVDCFNGLLVEYARS
KKARAVIRGLRAVSDFEGEFQMASMNKQLDSDIETVFFMTDTKYAFLSSSVVKEVAQFNGNVKGMVPDVVAKALVEKYNY
SR

Sequences:

>Translated_162_residues
MLNRVVYPGSFDPVTYGHLDIIKRAAQIFDEVIVAVFRNPRKNPLFSMDERVKLLKEVTKEIDRVQVDCFNGLLVEYARS
KKARAVIRGLRAVSDFEGEFQMASMNKQLDSDIETVFFMTDTKYAFLSSSVVKEVAQFNGNVKGMVPDVVAKALVEKYNY
SR
>Mature_162_residues
MLNRVVYPGSFDPVTYGHLDIIKRAAQIFDEVIVAVFRNPRKNPLFSMDERVKLLKEVTKEIDRVQVDCFNGLLVEYARS
KKARAVIRGLRAVSDFEGEFQMASMNKQLDSDIETVFFMTDTKYAFLSSSVVKEVAQFNGNVKGMVPDVVAKALVEKYNY
SR

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=157, Percent_Identity=46.4968152866242, Blast_Score=167, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18471; Mature: 18471

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRVVYPGSFDPVTYGHLDIIKRAAQIFDEVIVAVFRNPRKNPLFSMDERVKLLKEVTK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
EIDRVQVDCFNGLLVEYARSKKARAVIRGLRAVSDFEGEFQMASMNKQLDSDIETVFFMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHEEEEEC
DTKYAFLSSSVVKEVAQFNGNVKGMVPDVVAKALVEKYNYSR
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLNRVVYPGSFDPVTYGHLDIIKRAAQIFDEVIVAVFRNPRKNPLFSMDERVKLLKEVTK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
EIDRVQVDCFNGLLVEYARSKKARAVIRGLRAVSDFEGEFQMASMNKQLDSDIETVFFMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHEEEEEC
DTKYAFLSSSVVKEVAQFNGNVKGMVPDVVAKALVEKYNYSR
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]