Click here to switch to the map view.

The map label for this gene is fusA [H]

Identifier: 220931816

GI number: 220931816

Start: 1058120

End: 1060186

Strand: Direct

Name: fusA [H]

Synonym: Hore_09730

Alternate gene names: 220931816

Gene position: 1058120-1060186 (Clockwise)

Preceding gene: 220931815

Following gene: 220931817

Centisome position: 41.04

GC content: 39.72

Gene sequence:

>2067_bases
TTGGCTTCTGTAAAAACAGACAAAATTAGAAATCTGTGTTTAATCTCCCACGGGGGAGCGGGAAAAACAACAATAACTGA
AATGAGCCTTTATAATTCCGGTGTTATAAAGGAACCGGGCAGGGTAGAGGATGGTACAACTCATTCTGATTACATGCCTG
AAGAGAAAAAACATCAGTTTTCTGTAGTTAATTCGTTTTTTTCCATCCCCTGGAACGGAAATCAGATAAATTGGGTTGAC
ACCCCTGGTTATGCTGATTTCAGGGGTGAGGTTTCCAGTGCCCTGAAAATTGTAGATGCAGCAGTATTGATAATTAATGG
TAATTCAGGTATAGAAGTAAATACTAATTATGTCTGGACTATGGCTGAAGATAATAATGTAGCCCGTTTTGTATTTATCA
ACAAGATGGATAAAGACGGGGCCAAATTTGATAAGGTTTTTGAAGAAATACAAAATAATTTAAATGGACATTTTGTCCCC
CTTACTATTCCTTATGGTGAAGGAGAAAATTATAAGGGGATAATAGATCTCCTTAAAAAAGAAGCCCTGTTATATGGTGA
TGATGGAGAATCAAAATCTGATATCCCTGATGGGCTGGCAGACAGGGTTGAAGAACTCTGGACCGAATTACTAGAATCAG
TTGTTGAGCTGGATGATGAATTAATGATGAAGTATTTCGATGATGAAGAAATCACTGATAAAGAGATGATAAAAGGTTTG
ATTAATGGTGTCAGGGCAGGGGATATTATCCCCGTAATGGTTGGTTCTGCTATCAATAATTCAGGTATTAAAACCCTTCT
CAACTACTTATCAAGTCTGGTTCCAGCACCTACTGACATTGGTACAGTTACCGGTACATGGGAAGGGGAGGAAATAAAGA
TTGAAGCAGGGGAATCCGGTCCCTTTGTCGGTCAGATCGGAAAAACAATGGTAGATCCCTATATTGGAAAGCTTTCAATC
TTCAGGGTATTATCTGGTAAACTAAATACAGGTTCAGAAATTTTTGTTCCCAGGTTAAATAATACCATAAAAGCCAGTAA
ATTATACAAATTAAATGGGGAAGAACAGGAAACTGTGGATGAGTTAAAGGCCGGGGATATTGGTGCTATTGCCAAAATAG
ATGATCTGGAAACATCAGATACACTTTCTGACCCGGATTTTAAAGTAGAGCTTGATCCTATAATATTTCCTGAACCTATG
CTTACCAAAACAGCTCTTCCGGCTTCAGAAGGTGATGATGAAAAAATGTCAACCGTATTACACCGCATAAGCCAGGAAGA
CCCGACCTTTAAGGTAGAATATAATAAGGTCACTAAAGAACTTCTGGTTACAGGTATGGGTACAGTTCATCTGGATGTTA
TTAAAGACATCTGTAAGCGCAAATTCGGTGTTGAGTTTGTAACCGGTATTCCCAAGGTTGCCTATAAAGAAACAATCCAG
TCCAGGGTAGAAGTTGAGGAGAAATATAAAAAACAGAGTGGGGGCCGGGGTCAATATGGTCATGTATTCTTAAGGATTGA
ACCCCTTCCAAGAGGTAAGGGATTTGAATTTGATGAAGAAATTTTCGGGGGAGCCATTCCAAGTCAGTATATTCCAGCTG
TTGAAAAGGGTGTTGTTGAGGCTATGGAAGAAGGGGTTATGGCCGGATACCCTGTTGTCGACTGTAAGGTAACGGTTTAT
GACGGCTCATACCACAGTGTTGACTCCTCGGAAATGGCCTTTAAAATTGCAGCTTCGAAGGCCTTTAAAAAGGGTATGGA
ACAGGCTAAACCGGTCCTCCTGGAACCCATTATGGATGTTGAAGTTATTGTACCTGAAGAGTATATGGGGGATATAATGG
GTGATTTAAATTCAAGGCGTGGCAAGATTCAGGGAATGAGTTCCCGGGACGGCCTTCAGGTCATAAAAGCCCATGTACCC
CAGGCTGAGATGTTTACTTATGCTACCGATTTAAAATCCCTTACCGGGGGACATGGAAAGTTTACTATGAAATTTGCTTA
TTATGATAAAGTTCCCAAGAAGATTGAAGATGAGATAATTAAAGAAAGAAATACAGAAACAGCTTAA

Upstream 100 bases:

>100_bases
AATTTAACTGTTATGTGCTATATTATTTCTAGAGAGTGTTTTTATCTTTTTTATTTATTAAATATAAAACAAATAAAATA
TTGAAAGGTTGGTGTTAAGA

Downstream 100 bases:

>100_bases
AATTAAGTCTATAAAATATCAAACAATAAACCCTTCCGGACATCCGGGAGGGTTTTTTTAAGTTAATAATATAATATTAC
TGGAAGGGGTGGAGAATATA

Product: translation elongation factor G

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 688; Mature: 687

Protein sequence:

>688_residues
MASVKTDKIRNLCLISHGGAGKTTITEMSLYNSGVIKEPGRVEDGTTHSDYMPEEKKHQFSVVNSFFSIPWNGNQINWVD
TPGYADFRGEVSSALKIVDAAVLIINGNSGIEVNTNYVWTMAEDNNVARFVFINKMDKDGAKFDKVFEEIQNNLNGHFVP
LTIPYGEGENYKGIIDLLKKEALLYGDDGESKSDIPDGLADRVEELWTELLESVVELDDELMMKYFDDEEITDKEMIKGL
INGVRAGDIIPVMVGSAINNSGIKTLLNYLSSLVPAPTDIGTVTGTWEGEEIKIEAGESGPFVGQIGKTMVDPYIGKLSI
FRVLSGKLNTGSEIFVPRLNNTIKASKLYKLNGEEQETVDELKAGDIGAIAKIDDLETSDTLSDPDFKVELDPIIFPEPM
LTKTALPASEGDDEKMSTVLHRISQEDPTFKVEYNKVTKELLVTGMGTVHLDVIKDICKRKFGVEFVTGIPKVAYKETIQ
SRVEVEEKYKKQSGGRGQYGHVFLRIEPLPRGKGFEFDEEIFGGAIPSQYIPAVEKGVVEAMEEGVMAGYPVVDCKVTVY
DGSYHSVDSSEMAFKIAASKAFKKGMEQAKPVLLEPIMDVEVIVPEEYMGDIMGDLNSRRGKIQGMSSRDGLQVIKAHVP
QAEMFTYATDLKSLTGGHGKFTMKFAYYDKVPKKIEDEIIKERNTETA

Sequences:

>Translated_688_residues
MASVKTDKIRNLCLISHGGAGKTTITEMSLYNSGVIKEPGRVEDGTTHSDYMPEEKKHQFSVVNSFFSIPWNGNQINWVD
TPGYADFRGEVSSALKIVDAAVLIINGNSGIEVNTNYVWTMAEDNNVARFVFINKMDKDGAKFDKVFEEIQNNLNGHFVP
LTIPYGEGENYKGIIDLLKKEALLYGDDGESKSDIPDGLADRVEELWTELLESVVELDDELMMKYFDDEEITDKEMIKGL
INGVRAGDIIPVMVGSAINNSGIKTLLNYLSSLVPAPTDIGTVTGTWEGEEIKIEAGESGPFVGQIGKTMVDPYIGKLSI
FRVLSGKLNTGSEIFVPRLNNTIKASKLYKLNGEEQETVDELKAGDIGAIAKIDDLETSDTLSDPDFKVELDPIIFPEPM
LTKTALPASEGDDEKMSTVLHRISQEDPTFKVEYNKVTKELLVTGMGTVHLDVIKDICKRKFGVEFVTGIPKVAYKETIQ
SRVEVEEKYKKQSGGRGQYGHVFLRIEPLPRGKGFEFDEEIFGGAIPSQYIPAVEKGVVEAMEEGVMAGYPVVDCKVTVY
DGSYHSVDSSEMAFKIAASKAFKKGMEQAKPVLLEPIMDVEVIVPEEYMGDIMGDLNSRRGKIQGMSSRDGLQVIKAHVP
QAEMFTYATDLKSLTGGHGKFTMKFAYYDKVPKKIEDEIIKERNTETA
>Mature_687_residues
ASVKTDKIRNLCLISHGGAGKTTITEMSLYNSGVIKEPGRVEDGTTHSDYMPEEKKHQFSVVNSFFSIPWNGNQINWVDT
PGYADFRGEVSSALKIVDAAVLIINGNSGIEVNTNYVWTMAEDNNVARFVFINKMDKDGAKFDKVFEEIQNNLNGHFVPL
TIPYGEGENYKGIIDLLKKEALLYGDDGESKSDIPDGLADRVEELWTELLESVVELDDELMMKYFDDEEITDKEMIKGLI
NGVRAGDIIPVMVGSAINNSGIKTLLNYLSSLVPAPTDIGTVTGTWEGEEIKIEAGESGPFVGQIGKTMVDPYIGKLSIF
RVLSGKLNTGSEIFVPRLNNTIKASKLYKLNGEEQETVDELKAGDIGAIAKIDDLETSDTLSDPDFKVELDPIIFPEPML
TKTALPASEGDDEKMSTVLHRISQEDPTFKVEYNKVTKELLVTGMGTVHLDVIKDICKRKFGVEFVTGIPKVAYKETIQS
RVEVEEKYKKQSGGRGQYGHVFLRIEPLPRGKGFEFDEEIFGGAIPSQYIPAVEKGVVEAMEEGVMAGYPVVDCKVTVYD
GSYHSVDSSEMAFKIAASKAFKKGMEQAKPVLLEPIMDVEVIVPEEYMGDIMGDLNSRRGKIQGMSSRDGLQVIKAHVPQ
AEMFTYATDLKSLTGGHGKFTMKFAYYDKVPKKIEDEIIKERNTETA

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=696, Percent_Identity=32.6149425287356, Blast_Score=383, Evalue=1e-106,
Organism=Homo sapiens, GI19923640, Length=722, Percent_Identity=28.9473684210526, Blast_Score=306, Evalue=5e-83,
Organism=Homo sapiens, GI25306283, Length=390, Percent_Identity=31.5384615384615, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI25306287, Length=285, Percent_Identity=35.7894736842105, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI94966754, Length=137, Percent_Identity=29.9270072992701, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI4503483, Length=189, Percent_Identity=26.984126984127, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI1789738, Length=699, Percent_Identity=40.2002861230329, Blast_Score=527, Evalue=1e-151,
Organism=Escherichia coli, GI1790835, Length=486, Percent_Identity=27.5720164609054, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI48994988, Length=144, Percent_Identity=32.6388888888889, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17533571, Length=692, Percent_Identity=31.7919075144509, Blast_Score=380, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17556745, Length=719, Percent_Identity=24.3393602225313, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17506493, Length=808, Percent_Identity=23.1435643564356, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17557151, Length=146, Percent_Identity=29.4520547945205, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71988819, Length=137, Percent_Identity=31.3868613138686, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71988811, Length=137, Percent_Identity=31.3868613138686, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323098, Length=697, Percent_Identity=31.9942611190818, Blast_Score=379, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6322359, Length=775, Percent_Identity=24.7741935483871, Blast_Score=225, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6324707, Length=150, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320593, Length=150, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24582462, Length=693, Percent_Identity=32.3232323232323, Blast_Score=384, Evalue=1e-106,
Organism=Drosophila melanogaster, GI221458488, Length=730, Percent_Identity=26.4383561643836, Blast_Score=256, Evalue=5e-68,
Organism=Drosophila melanogaster, GI24585711, Length=178, Percent_Identity=26.4044943820225, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24585713, Length=178, Percent_Identity=26.4044943820225, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24585709, Length=178, Percent_Identity=26.4044943820225, Blast_Score=74, Evalue=5e-13,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 76113; Mature: 75982

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVKTDKIRNLCLISHGGAGKTTITEMSLYNSGVIKEPGRVEDGTTHSDYMPEEKKHQF
CCCCCCHHHCCEEEEECCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SVVNSFFSIPWNGNQINWVDTPGYADFRGEVSSALKIVDAAVLIINGNSGIEVNTNYVWT
HHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHEEEEEEEEEECCCCEEEECCEEEE
MAEDNNVARFVFINKMDKDGAKFDKVFEEIQNNLNGHFVPLTIPYGEGENYKGIIDLLKK
EECCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHH
EALLYGDDGESKSDIPDGLADRVEELWTELLESVVELDDELMMKYFDDEEITDKEMIKGL
HHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHH
INGVRAGDIIPVMVGSAINNSGIKTLLNYLSSLVPAPTDIGTVTGTWEGEEIKIEAGESG
HCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEECCCCC
PFVGQIGKTMVDPYIGKLSIFRVLSGKLNTGSEIFVPRLNNTIKASKLYKLNGEEQETVD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEECCEEEEECCCHHHHHH
ELKAGDIGAIAKIDDLETSDTLSDPDFKVELDPIIFPEPMLTKTALPASEGDDEKMSTVL
HHCCCCCCCEEEECCCCCCCCCCCCCCEEEECCEECCCCCHHHHCCCCCCCCHHHHHHHH
HRISQEDPTFKVEYNKVTKELLVTGMGTVHLDVIKDICKRKFGVEFVTGIPKVAYKETIQ
HHHCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHH
SRVEVEEKYKKQSGGRGQYGHVFLRIEPLPRGKGFEFDEEIFGGAIPSQYIPAVEKGVVE
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHCCCCCHHHCCHHHHHHHH
AMEEGVMAGYPVVDCKVTVYDGSYHSVDSSEMAFKIAASKAFKKGMEQAKPVLLEPIMDV
HHHCCCCCCCCEEEEEEEEECCCCCCCCCCHHEEHHHHHHHHHHHHHHCCCEEECCCCCE
EVIVPEEYMGDIMGDLNSRRGKIQGMSSRDGLQVIKAHVPQAEMFTYATDLKSLTGGHGK
EEEECHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCE
FTMKFAYYDKVPKKIEDEIIKERNTETA
EEEEEEHHHHCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ASVKTDKIRNLCLISHGGAGKTTITEMSLYNSGVIKEPGRVEDGTTHSDYMPEEKKHQF
CCCCCHHHCCEEEEECCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SVVNSFFSIPWNGNQINWVDTPGYADFRGEVSSALKIVDAAVLIINGNSGIEVNTNYVWT
HHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHEEEEEEEEEECCCCEEEECCEEEE
MAEDNNVARFVFINKMDKDGAKFDKVFEEIQNNLNGHFVPLTIPYGEGENYKGIIDLLKK
EECCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHH
EALLYGDDGESKSDIPDGLADRVEELWTELLESVVELDDELMMKYFDDEEITDKEMIKGL
HHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHH
INGVRAGDIIPVMVGSAINNSGIKTLLNYLSSLVPAPTDIGTVTGTWEGEEIKIEAGESG
HCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEECCCCC
PFVGQIGKTMVDPYIGKLSIFRVLSGKLNTGSEIFVPRLNNTIKASKLYKLNGEEQETVD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEECCEEEEECCCHHHHHH
ELKAGDIGAIAKIDDLETSDTLSDPDFKVELDPIIFPEPMLTKTALPASEGDDEKMSTVL
HHCCCCCCCEEEECCCCCCCCCCCCCCEEEECCEECCCCCHHHHCCCCCCCCHHHHHHHH
HRISQEDPTFKVEYNKVTKELLVTGMGTVHLDVIKDICKRKFGVEFVTGIPKVAYKETIQ
HHHCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHH
SRVEVEEKYKKQSGGRGQYGHVFLRIEPLPRGKGFEFDEEIFGGAIPSQYIPAVEKGVVE
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHCCCCCHHHCCHHHHHHHH
AMEEGVMAGYPVVDCKVTVYDGSYHSVDSSEMAFKIAASKAFKKGMEQAKPVLLEPIMDV
HHHCCCCCCCCEEEEEEEEECCCCCCCCCCHHEEHHHHHHHHHHHHHHCCCEEECCCCCE
EVIVPEEYMGDIMGDLNSRRGKIQGMSSRDGLQVIKAHVPQAEMFTYATDLKSLTGGHGK
EEEECHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCE
FTMKFAYYDKVPKKIEDEIIKERNTETA
EEEEEEHHHHCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA