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The map label for this gene is ftsA [H]

Identifier: 220931755

GI number: 220931755

Start: 985766

End: 987031

Strand: Direct

Name: ftsA [H]

Synonym: Hore_09120

Alternate gene names: 220931755

Gene position: 985766-987031 (Clockwise)

Preceding gene: 220931754

Following gene: 220931756

Centisome position: 38.24

GC content: 43.05

Gene sequence:

>1266_bases
GTGGGTATTCGTAGAATTATTACCGGACTAGATATAGGGACAACAAAGATTTGTGCTATGATAGCAGAAGTTAATTCTGA
AGATAAACTGGATATCATTGGTATTGGCCTCTCCCCTTCCCATGGTTTAAGGAAAGGTATTGTGGTTGATATAGATAAAA
CCAGTAATGCCATTAAACAGGCCGTAGAGAAAGCAGAAAGAATGGCCGGGCGGCAGATAGATTCAGCTTTTGTCGGAATC
GCCGGTTCCCACATATCTTCTCTCAATAGTCATGGGGTTGTAGCTGTTAGTGGAGAAGAAAAGGAGATAAAACCCAGTGA
TATCCAGCGGGTTATGGAAGCTGCCAAGATAATTCCCCTTTCTGCCGAGGAAGAAATTATTCATGTCCTGGCCCGGGAAT
TTATAGTTGATGGCTGTCCTGGAATAAAGGATCCTCTGGGTATGTCAGGGGTCAGGCTAGAAGTGGAAACCCATATCGTT
ACCGGTTCTACAACTTCGATACAGAATCTGGTAAAAAGTGTACTCAGGGCAGGACTGGATGTTGATGATATTGTTCTGGA
ACCCCTTGCTTCCAGTGAATCGGTTTTAACCGAGGATGAGAAGGAATTAGGGGTAGCCCTGGTAGATGTGGGTGGTGGAA
CTACTGATCTTATTGTTTTTCAGGAGGGTAGTATTACATACACCTCTGTTTTACCAGTTGGGGGAAATCATGTTAGTAAT
GACATAGCTGTTGGATTAAGAACCCCGATAGCTGAAGCAGAGAAGATTAAAATAATGGCAGGTTCGGCAACTACAAAAAA
TATAGGAGATGATGAATATATAGAAGTGGTTTCCGCCAGTCGGAAAAAAAAGAATAAAATTCCGCGAAAGGCTCTGTGTG
AAGTCATAGAACCCCGGATGCAGGAAATTTTCAATCTGGTAAAAAGGGAGCTGGATGAAGTTGGCCCCCGGGATTTAACA
CCGGCCGGTGTTGTTTTGACCGGTGGTGCTTCCCTGCTTGAGGGAGCAGAAGAGCTGGCTTCTGAGGTTATCGGCCTGCC
GGTTAGACTTGGGGAACCTGATTATGTAAATGGGTTAACCGATGTAATCGATAATCCGGTATATGTGAAAAAAGGCAAAC
AGGTTCCTAAAGCAATATTCTCAACAGCGGTTGGATTGGTAGAGTATGGATTAAAATATGACCAGCCATCCCGTGATAAT
AATCGTGGCGAAATAGTTAGTGATTTTTTCGGAAAACTTAAAAACTGGTTTAATGATTTTTTCTAG

Upstream 100 bases:

>100_bases
CTCAAAAAATGAAGTAAAAAATTTTTATAAAAAAAGGAATATGACCCTGGCATGTTGAATTAGTTTTTTAGAGTTTAGCC
GGGAGAGGAGGTATAAATTT

Downstream 100 bases:

>100_bases
GAAAGGAGGTACTACCCGGTGTTTGATATCGGAACAGAAATAGAGCAATTTGCCAATATAAAGGTTGTTGGTGTCGGTGG
GGGTGGCAATAATGCAGTAA

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MGIRRIITGLDIGTTKICAMIAEVNSEDKLDIIGIGLSPSHGLRKGIVVDIDKTSNAIKQAVEKAERMAGRQIDSAFVGI
AGSHISSLNSHGVVAVSGEEKEIKPSDIQRVMEAAKIIPLSAEEEIIHVLAREFIVDGCPGIKDPLGMSGVRLEVETHIV
TGSTTSIQNLVKSVLRAGLDVDDIVLEPLASSESVLTEDEKELGVALVDVGGGTTDLIVFQEGSITYTSVLPVGGNHVSN
DIAVGLRTPIAEAEKIKIMAGSATTKNIGDDEYIEVVSASRKKKNKIPRKALCEVIEPRMQEIFNLVKRELDEVGPRDLT
PAGVVLTGGASLLEGAEELASEVIGLPVRLGEPDYVNGLTDVIDNPVYVKKGKQVPKAIFSTAVGLVEYGLKYDQPSRDN
NRGEIVSDFFGKLKNWFNDFF

Sequences:

>Translated_421_residues
MGIRRIITGLDIGTTKICAMIAEVNSEDKLDIIGIGLSPSHGLRKGIVVDIDKTSNAIKQAVEKAERMAGRQIDSAFVGI
AGSHISSLNSHGVVAVSGEEKEIKPSDIQRVMEAAKIIPLSAEEEIIHVLAREFIVDGCPGIKDPLGMSGVRLEVETHIV
TGSTTSIQNLVKSVLRAGLDVDDIVLEPLASSESVLTEDEKELGVALVDVGGGTTDLIVFQEGSITYTSVLPVGGNHVSN
DIAVGLRTPIAEAEKIKIMAGSATTKNIGDDEYIEVVSASRKKKNKIPRKALCEVIEPRMQEIFNLVKRELDEVGPRDLT
PAGVVLTGGASLLEGAEELASEVIGLPVRLGEPDYVNGLTDVIDNPVYVKKGKQVPKAIFSTAVGLVEYGLKYDQPSRDN
NRGEIVSDFFGKLKNWFNDFF
>Mature_420_residues
GIRRIITGLDIGTTKICAMIAEVNSEDKLDIIGIGLSPSHGLRKGIVVDIDKTSNAIKQAVEKAERMAGRQIDSAFVGIA
GSHISSLNSHGVVAVSGEEKEIKPSDIQRVMEAAKIIPLSAEEEIIHVLAREFIVDGCPGIKDPLGMSGVRLEVETHIVT
GSTTSIQNLVKSVLRAGLDVDDIVLEPLASSESVLTEDEKELGVALVDVGGGTTDLIVFQEGSITYTSVLPVGGNHVSND
IAVGLRTPIAEAEKIKIMAGSATTKNIGDDEYIEVVSASRKKKNKIPRKALCEVIEPRMQEIFNLVKRELDEVGPRDLTP
AGVVLTGGASLLEGAEELASEVIGLPVRLGEPDYVNGLTDVIDNPVYVKKGKQVPKAIFSTAVGLVEYGLKYDQPSRDNN
RGEIVSDFFGKLKNWFNDFF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=432, Percent_Identity=38.6574074074074, Blast_Score=301, Evalue=4e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 45133; Mature: 45002

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIRRIITGLDIGTTKICAMIAEVNSEDKLDIIGIGLSPSHGLRKGIVVDIDKTSNAIKQ
CCHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHH
AVEKAERMAGRQIDSAFVGIAGSHISSLNSHGVVAVSGEEKEIKPSDIQRVMEAAKIIPL
HHHHHHHHHCCHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCC
SAEEEIIHVLAREFIVDGCPGIKDPLGMSGVRLEVETHIVTGSTTSIQNLVKSVLRAGLD
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHCCCC
VDDIVLEPLASSESVLTEDEKELGVALVDVGGGTTDLIVFQEGSITYTSVLPVGGNHVSN
HHHHHHCCCCCCCCHHCCCCHHHCEEEEEECCCCEEEEEEECCCEEEEEEEECCCCCCCC
DIAVGLRTPIAEAEKIKIMAGSATTKNIGDDEYIEVVSASRKKKNKIPRKALCEVIEPRM
CEEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QEIFNLVKRELDEVGPRDLTPAGVVLTGGASLLEGAEELASEVIGLPVRLGEPDYVNGLT
HHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCEECCCCHHHCCHH
DVIDNPVYVKKGKQVPKAIFSTAVGLVEYGLKYDQPSRDNNRGEIVSDFFGKLKNWFNDF
HHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
F
C
>Mature Secondary Structure 
GIRRIITGLDIGTTKICAMIAEVNSEDKLDIIGIGLSPSHGLRKGIVVDIDKTSNAIKQ
CHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHH
AVEKAERMAGRQIDSAFVGIAGSHISSLNSHGVVAVSGEEKEIKPSDIQRVMEAAKIIPL
HHHHHHHHHCCHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCC
SAEEEIIHVLAREFIVDGCPGIKDPLGMSGVRLEVETHIVTGSTTSIQNLVKSVLRAGLD
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHCCCC
VDDIVLEPLASSESVLTEDEKELGVALVDVGGGTTDLIVFQEGSITYTSVLPVGGNHVSN
HHHHHHCCCCCCCCHHCCCCHHHCEEEEEECCCCEEEEEEECCCEEEEEEEECCCCCCCC
DIAVGLRTPIAEAEKIKIMAGSATTKNIGDDEYIEVVSASRKKKNKIPRKALCEVIEPRM
CEEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QEIFNLVKRELDEVGPRDLTPAGVVLTGGASLLEGAEELASEVIGLPVRLGEPDYVNGLT
HHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCEECCCCHHHCCHH
DVIDNPVYVKKGKQVPKAIFSTAVGLVEYGLKYDQPSRDNNRGEIVSDFFGKLKNWFNDF
HHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]