Click here to switch to the map view.

The map label for this gene is fadR [H]

Identifier: 220931688

GI number: 220931688

Start: 908363

End: 908935

Strand: Direct

Name: fadR [H]

Synonym: Hore_08440

Alternate gene names: 220931688

Gene position: 908363-908935 (Clockwise)

Preceding gene: 220931687

Following gene: 220931689

Centisome position: 35.23

GC content: 31.24

Gene sequence:

>573_bases
ATGAAAATACGGGAAAATAAGAAAGAATTAATCAGAGAGGCAGCAATAAAAGTTATATCAAAATTTGGTTTTTATAATAC
TACAACTGCCAGTATTGCAGAAGAAGCTGGTGTAGCAGTAGGAACAATTTATAATTATTTCACTAATAAAGAGGAGATAT
TGGAATACATATTTGCTGTTGAATTTGAAAAAAGAATGAGTTATCTAAAAGAGATTGCACAAGAAGATAGGTCTATATAT
GAAAAGATAGAATTATTTCTGGAAAAGCATTTTATGGAGGTAAAAGAAAACCCCAGTCTGGGCAAGATTCTGGTCCGGGA
AAAAGATTTTTCCCGAAAAAAGGGCAATATTGCTATTAATGAATATTTAAATAAATTACCACTACTTATTGAGGAGATCT
TAAATAAAAGTATAGAAAAGAAAGCCATTGAGCCCTGTAATACATATTTAATCTCAACAGCTTTATTTGGAGCTATTCAG
GGAATTGTAGAAAGGGCTGTTGGGGAGGAAGATTTTAATTTGTTTGATCAGGCTGCAGCAGAACTTGTAAAAATATTGAA
AGAAGGAATATAA

Upstream 100 bases:

>100_bases
AACAGGTAAAGAATCTGTTATAATACTGTATGAATGAGTAGTCATTCAGTTTCCAAGGAATTTTATTAGATTTATTTAGA
TTGGTATAGGGGGATCTATT

Downstream 100 bases:

>100_bases
AAATTTCAAGCAGGACTGAATGATCATTCATTCATAAAAAGATAGGAGGGATTATTTTGCGAAAACTTGTTGATTTTACG
ACCAGGTATCCAATACCAAT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKIRENKKELIREAAIKVISKFGFYNTTTASIAEEAGVAVGTIYNYFTNKEEILEYIFAVEFEKRMSYLKEIAQEDRSIY
EKIELFLEKHFMEVKENPSLGKILVREKDFSRKKGNIAINEYLNKLPLLIEEILNKSIEKKAIEPCNTYLISTALFGAIQ
GIVERAVGEEDFNLFDQAAAELVKILKEGI

Sequences:

>Translated_190_residues
MKIRENKKELIREAAIKVISKFGFYNTTTASIAEEAGVAVGTIYNYFTNKEEILEYIFAVEFEKRMSYLKEIAQEDRSIY
EKIELFLEKHFMEVKENPSLGKILVREKDFSRKKGNIAINEYLNKLPLLIEEILNKSIEKKAIEPCNTYLISTALFGAIQ
GIVERAVGEEDFNLFDQAAAELVKILKEGI
>Mature_190_residues
MKIRENKKELIREAAIKVISKFGFYNTTTASIAEEAGVAVGTIYNYFTNKEEILEYIFAVEFEKRMSYLKEIAQEDRSIY
EKIELFLEKHFMEVKENPSLGKILVREKDFSRKKGNIAINEYLNKLPLLIEEILNKSIEKKAIEPCNTYLISTALFGAIQ
GIVERAVGEEDFNLFDQAAAELVKILKEGI

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21842; Mature: 21842

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRENKKELIREAAIKVISKFGFYNTTTASIAEEAGVAVGTIYNYFTNKEEILEYIFAV
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHH
EFEKRMSYLKEIAQEDRSIYEKIELFLEKHFMEVKENPSLGKILVREKDFSRKKGNIAIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHH
EYLNKLPLLIEEILNKSIEKKAIEPCNTYLISTALFGAIQGIVERAVGEEDFNLFDQAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ELVKILKEGI
HHHHHHHHCC
>Mature Secondary Structure
MKIRENKKELIREAAIKVISKFGFYNTTTASIAEEAGVAVGTIYNYFTNKEEILEYIFAV
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHH
EFEKRMSYLKEIAQEDRSIYEKIELFLEKHFMEVKENPSLGKILVREKDFSRKKGNIAIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHH
EYLNKLPLLIEEILNKSIEKKAIEPCNTYLISTALFGAIQGIVERAVGEEDFNLFDQAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ELVKILKEGI
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]