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The map label for this gene is mgtC [H]

Identifier: 220931623

GI number: 220931623

Start: 835033

End: 835698

Strand: Direct

Name: mgtC [H]

Synonym: Hore_07790

Alternate gene names: 220931623

Gene position: 835033-835698 (Clockwise)

Preceding gene: 220931622

Following gene: 220931624

Centisome position: 32.39

GC content: 40.39

Gene sequence:

>666_bases
ATGTTTAATGTTTTAGATATCACATACCGGTTGTTGACGGCTCTTTTGTTAGGAGGCCTGGTTGGCTGGGAACGGGAACG
GCATGAAAGACCGGCCGGGTTTAGAACCCATATTCTGGTCACTGTGGGTTCAGCCCTTTTGATGGTAATTTCCCTGAGTA
TGGTTGAATTATATCCTGATACTGATGCAGACCCGGCCAGGATAGCAGCCCAGGTTGTCAGCGGGATCGGTTTTTTAGGA
GCCGGTACAATAATCAGGGAAGGTTTTTCAGTCAAGGGTTTAACTACAGCAGCCAGCCTGTGGACTGTGGCTGCTATTGG
ACTGGCAGCAGGAGCAGGATATTATAAAATAAGTACCATTACTACTCTCATTGTTTTTATTACACTTTTTTTTCTTTCCA
AACTGGAACTCGGTGTCAGTAGTGTTAATACCAGGATTTTAAAGTGTAGGGTTATGGATAAACCCGGTCTTCTTGGTGAG
ATCGGGGTAACTCTGGGTTCAAAGGAGATAAATATAACCAATGTAAATATAGAGAAAAACTCAAATGAAGGTGAAATGGA
TGTTGAACTAATTGTTAAAATACCGAGAAATTTTGATAAAAGTATAATTAATCAGGAGTTATTAAAAATTGAAGGAATAA
GAGCTATAAACTGGCGTAATCTTTAG

Upstream 100 bases:

>100_bases
AAAAGGGGTTTTGCCCGGGGCTTTATTGACCGGATGAAGATGTATTATGATATTTTAAAAGTTTTTATCAAGAAAATATA
ATTTGAGTTGGTGGTAATAA

Downstream 100 bases:

>100_bases
GGGGATGGGGTCAAATGTTAGTAGCAATAAAACCATCAAATAAGTTCGGTAGTATTTTTAGATATATAATACTTAACAGG
AAATCTAAAAAAATAAAATG

Product: MgtC/SapB transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MFNVLDITYRLLTALLLGGLVGWERERHERPAGFRTHILVTVGSALLMVISLSMVELYPDTDADPARIAAQVVSGIGFLG
AGTIIREGFSVKGLTTAASLWTVAAIGLAAGAGYYKISTITTLIVFITLFFLSKLELGVSSVNTRILKCRVMDKPGLLGE
IGVTLGSKEINITNVNIEKNSNEGEMDVELIVKIPRNFDKSIINQELLKIEGIRAINWRNL

Sequences:

>Translated_221_residues
MFNVLDITYRLLTALLLGGLVGWERERHERPAGFRTHILVTVGSALLMVISLSMVELYPDTDADPARIAAQVVSGIGFLG
AGTIIREGFSVKGLTTAASLWTVAAIGLAAGAGYYKISTITTLIVFITLFFLSKLELGVSSVNTRILKCRVMDKPGLLGE
IGVTLGSKEINITNVNIEKNSNEGEMDVELIVKIPRNFDKSIINQELLKIEGIRAINWRNL
>Mature_221_residues
MFNVLDITYRLLTALLLGGLVGWERERHERPAGFRTHILVTVGSALLMVISLSMVELYPDTDADPARIAAQVVSGIGFLG
AGTIIREGFSVKGLTTAASLWTVAAIGLAAGAGYYKISTITTLIVFITLFFLSKLELGVSSVNTRILKCRVMDKPGLLGE
IGVTLGSKEINITNVNIEKNSNEGEMDVELIVKIPRNFDKSIINQELLKIEGIRAINWRNL

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=129, Percent_Identity=40.3100775193798, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 24074; Mature: 24074

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNVLDITYRLLTALLLGGLVGWERERHERPAGFRTHILVTVGSALLMVISLSMVELYPD
CCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
TDADPARIAAQVVSGIGFLGAGTIIREGFSVKGLTTAASLWTVAAIGLAAGAGYYKISTI
CCCCHHHHHHHHHHHCCHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHH
TTLIVFITLFFLSKLELGVSSVNTRILKCRVMDKPGLLGEIGVTLGSKEINITNVNIEKN
HHHHHHHHHHHHHHHHHCHHHHCEEEEEEEECCCCCCEEHHCEEECCCEEEEEEEEEEEC
SNEGEMDVELIVKIPRNFDKSIINQELLKIEGIRAINWRNL
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCEEEECCCCC
>Mature Secondary Structure
MFNVLDITYRLLTALLLGGLVGWERERHERPAGFRTHILVTVGSALLMVISLSMVELYPD
CCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
TDADPARIAAQVVSGIGFLGAGTIIREGFSVKGLTTAASLWTVAAIGLAAGAGYYKISTI
CCCCHHHHHHHHHHHCCHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHH
TTLIVFITLFFLSKLELGVSSVNTRILKCRVMDKPGLLGEIGVTLGSKEINITNVNIEKN
HHHHHHHHHHHHHHHHHCHHHHCEEEEEEEECCCCCCEEHHCEEECCCEEEEEEEEEEEC
SNEGEMDVELIVKIPRNFDKSIINQELLKIEGIRAINWRNL
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA