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The map label for this gene is codY [H]

Identifier: 220931602

GI number: 220931602

Start: 816642

End: 817424

Strand: Direct

Name: codY [H]

Synonym: Hore_07580

Alternate gene names: 220931602

Gene position: 816642-817424 (Clockwise)

Preceding gene: 220931601

Following gene: 220931603

Centisome position: 31.68

GC content: 37.42

Gene sequence:

>783_bases
ATGGATCAATTGTTAGAAAAAAGCAGAAAAATAAATCGCTTGTTGCAAAGAACTGGAGGAAAACCAGTAGATTTTAAAGA
AATGGCCCAGGTATTAAAGGAAGCTATAAAATGTAATATTTATATTGCGAGTAAGAAGGGGAAAATTTTAGGATATAGTC
TCCTCAGTGACTTTGAATGTGATATTATGGAAGAAGAGGTTATTGAAAAGGGACATTTTCCTGAAGATTACAATGAAGGA
TTAATGCGTGTCCAGGAAACGAGGGCCAATATTAAACAAAAACAGGGTAATTGTGTATTTACAGATGGAGAAGAGTGCCT
GTTTCAAAATAAATTAACTACAATAGTTCCTGTTATTGGTGGCGGTGACAGGTTAGGTACTCTGGTTCTGGCCCGTTATG
ATGAAGAGTTTACAGATCATGACCTGGTTCTTGCCGAATATGGTTCATCAGTTGTTGGTATGGAAATACTCAGGTCCAGA
AGTGAAAAAATAGAAAAAGAGGCCAGGAAAAAGGCGGCTGTCCAGATAGCTATTGATACTTTATCTTACTCTGAACTTGA
AGCAATAGAGCATATATTTGAAGAGCTGGATGGTAAAGAGGGGCTTCTGGTAGCCAGTAAAATTGCCGACAGGGTAGGTA
TTACCCGCTCTGTTATTGTTAATGCCCTTAGAAAATTTGAAAGTGCTGGTGTAATTGAATCACGTTCTCTGGGAATGAAG
GGAACATATATAAAAATCCTTAATGACTATCTACTGGATGAACTGGAAAAATTAAGGGCCTAA

Upstream 100 bases:

>100_bases
AATCCATGTTATGGGGTATCTAATATTAGTCTACCAACAAGAAAAGTTTATAAGGTAATAGTTGTTGGTTACTAAATAAT
AAGAATGGAGGTAGATAAAA

Downstream 100 bases:

>100_bases
ACCCTTATTTAGAAAGTCCTCAAAGGATTCTATCCTTGGGGACTTTTTTTATTTATCTATCTTAATACTGATAATTTGTT
ATTAATATGCAGGAACTTCC

Product: transcriptional repressor CodY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MDQLLEKSRKINRLLQRTGGKPVDFKEMAQVLKEAIKCNIYIASKKGKILGYSLLSDFECDIMEEEVIEKGHFPEDYNEG
LMRVQETRANIKQKQGNCVFTDGEECLFQNKLTTIVPVIGGGDRLGTLVLARYDEEFTDHDLVLAEYGSSVVGMEILRSR
SEKIEKEARKKAAVQIAIDTLSYSELEAIEHIFEELDGKEGLLVASKIADRVGITRSVIVNALRKFESAGVIESRSLGMK
GTYIKILNDYLLDELEKLRA

Sequences:

>Translated_260_residues
MDQLLEKSRKINRLLQRTGGKPVDFKEMAQVLKEAIKCNIYIASKKGKILGYSLLSDFECDIMEEEVIEKGHFPEDYNEG
LMRVQETRANIKQKQGNCVFTDGEECLFQNKLTTIVPVIGGGDRLGTLVLARYDEEFTDHDLVLAEYGSSVVGMEILRSR
SEKIEKEARKKAAVQIAIDTLSYSELEAIEHIFEELDGKEGLLVASKIADRVGITRSVIVNALRKFESAGVIESRSLGMK
GTYIKILNDYLLDELEKLRA
>Mature_260_residues
MDQLLEKSRKINRLLQRTGGKPVDFKEMAQVLKEAIKCNIYIASKKGKILGYSLLSDFECDIMEEEVIEKGHFPEDYNEG
LMRVQETRANIKQKQGNCVFTDGEECLFQNKLTTIVPVIGGGDRLGTLVLARYDEEFTDHDLVLAEYGSSVVGMEILRSR
SEKIEKEARKKAAVQIAIDTLSYSELEAIEHIFEELDGKEGLLVASKIADRVGITRSVIVNALRKFESAGVIESRSLGMK
GTYIKILNDYLLDELEKLRA

Specific function: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of

COG id: COG4465

COG function: function code K; Pleiotropic transcriptional repressor

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CodY family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014154
- InterPro:   IPR010312
- InterPro:   IPR013198
- InterPro:   IPR011991 [H]

Pfam domain/function: PF06018 CodY; PF08222 HTH_CodY [H]

EC number: NA

Molecular weight: Translated: 29284; Mature: 29284

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLLEKSRKINRLLQRTGGKPVDFKEMAQVLKEAIKCNIYIASKKGKILGYSLLSDFEC
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCEEEHHHHCCCCC
DIMEEEVIEKGHFPEDYNEGLMRVQETRANIKQKQGNCVFTDGEECLFQNKLTTIVPVIG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHCCCHHEEEEEC
GGDRLGTLVLARYDEEFTDHDLVLAEYGSSVVGMEILRSRSEKIEKEARKKAAVQIAIDT
CCCHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHH
LSYSELEAIEHIFEELDGKEGLLVASKIADRVGITRSVIVNALRKFESAGVIESRSLGMK
HCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCC
GTYIKILNDYLLDELEKLRA
CHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDQLLEKSRKINRLLQRTGGKPVDFKEMAQVLKEAIKCNIYIASKKGKILGYSLLSDFEC
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCEEEHHHHCCCCC
DIMEEEVIEKGHFPEDYNEGLMRVQETRANIKQKQGNCVFTDGEECLFQNKLTTIVPVIG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHCCCHHEEEEEC
GGDRLGTLVLARYDEEFTDHDLVLAEYGSSVVGMEILRSRSEKIEKEARKKAAVQIAIDT
CCCHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHH
LSYSELEAIEHIFEELDGKEGLLVASKIADRVGITRSVIVNALRKFESAGVIESRSLGMK
HCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCC
GTYIKILNDYLLDELEKLRA
CHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]