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The map label for this gene is zupT [H]

Identifier: 220931587

GI number: 220931587

Start: 801010

End: 801828

Strand: Direct

Name: zupT [H]

Synonym: Hore_07430

Alternate gene names: 220931587

Gene position: 801010-801828 (Clockwise)

Preceding gene: 220931586

Following gene: 220931588

Centisome position: 31.07

GC content: 36.14

Gene sequence:

>819_bases
GTGATTATAATAGAAAACGTAATACCTGCCTTTATAATTACACTATTTGCTGGTCTATCAACTGGAATCGGGAGTGCTCT
GGCCCTCTTCGCCCGGAGAACTAATACTAAATTTCTTTCGATATCTCTGGGTTTTTCAGCCGGAGTTATGGTTTATGTTT
CTTTTGTAGAATTGTTTAATGGAGCCCTGGAAACTTTAATAAAGGTCCATGGTAGTAAAACGGGCCAGATATTAGCGGTT
TTATCTTTTTTTACAGGGATATTAATAATTGCCATTATTGACAATATGGTGCCCGAACATGAGAACCCACATCAGGTTAG
AAAAGAAAGAGAACTTATAAATATAAAAAAAGAAAATGTTAATAATGATTTTTCATTAAAGAAAATGGGGCTTCTTTCTG
CCGTGGCTATATCAATACATAACTTTCCGGAGGGTATAGCAACCTTTGCCTCATCATTGTCAGACCTTACGGTCGGGGTG
TCTATTGCTGTTGCTATTGCAATACATAATATTCCGGAAGGTGTTTCGGTATCAGTCCCCATTTATTATGCTACTGGTAA
CAAAAAGAAAGCTTTTATATACTCATTCATGTCAGGGTTATCAGAACCTTTAGGAGCTTTAATAGGTTATGCTTTTTTTA
AAATATTTTTATCTGATACTGTCCTTGGTATTATTTTCGGACTGGTTGCGGGAATAATGGTATTTATTTCAATAGATGAA
CTTCTTCCAGCTTCAAGAAGGTATGGTCAGGGTCATCAGGAGATATACAGCTTCATAGCAGGTATGGCTGTAATGGCCAT
AAGTTTACTGTTATTATAA

Upstream 100 bases:

>100_bases
TATGCGAAAATACCAGAAAAAAATCCAAAGAGTTAATAGACAGAATTAATCTGGAATTCTCTGATATTTATGAGTTATAA
TCTAACATAAAATAAAGAAG

Downstream 100 bases:

>100_bases
AAAATTTTATAAATACAAATGTTATAAATATCTGGGTTTTTTCCATGACTGTGGAGAAAACCTTTTTTGTTTACTTTTTA
GTACTTTTTTCTCTAAAATG

Product: zinc/iron permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MIIIENVIPAFIITLFAGLSTGIGSALALFARRTNTKFLSISLGFSAGVMVYVSFVELFNGALETLIKVHGSKTGQILAV
LSFFTGILIIAIIDNMVPEHENPHQVRKERELINIKKENVNNDFSLKKMGLLSAVAISIHNFPEGIATFASSLSDLTVGV
SIAVAIAIHNIPEGVSVSVPIYYATGNKKKAFIYSFMSGLSEPLGALIGYAFFKIFLSDTVLGIIFGLVAGIMVFISIDE
LLPASRRYGQGHQEIYSFIAGMAVMAISLLLL

Sequences:

>Translated_272_residues
MIIIENVIPAFIITLFAGLSTGIGSALALFARRTNTKFLSISLGFSAGVMVYVSFVELFNGALETLIKVHGSKTGQILAV
LSFFTGILIIAIIDNMVPEHENPHQVRKERELINIKKENVNNDFSLKKMGLLSAVAISIHNFPEGIATFASSLSDLTVGV
SIAVAIAIHNIPEGVSVSVPIYYATGNKKKAFIYSFMSGLSEPLGALIGYAFFKIFLSDTVLGIIFGLVAGIMVFISIDE
LLPASRRYGQGHQEIYSFIAGMAVMAISLLLL
>Mature_272_residues
MIIIENVIPAFIITLFAGLSTGIGSALALFARRTNTKFLSISLGFSAGVMVYVSFVELFNGALETLIKVHGSKTGQILAV
LSFFTGILIIAIIDNMVPEHENPHQVRKERELINIKKENVNNDFSLKKMGLLSAVAISIHNFPEGIATFASSLSDLTVGV
SIAVAIAIHNIPEGVSVSVPIYYATGNKKKAFIYSFMSGLSEPLGALIGYAFFKIFLSDTVLGIIFGLVAGIMVFISIDE
LLPASRRYGQGHQEIYSFIAGMAVMAISLLLL

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577418, Length=323, Percent_Identity=26.0061919504644, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI229577422, Length=331, Percent_Identity=25.0755287009063, Blast_Score=81, Evalue=8e-16,
Organism=Escherichia coli, GI1789419, Length=262, Percent_Identity=36.2595419847328, Blast_Score=159, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17507805, Length=313, Percent_Identity=26.8370607028754, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24652846, Length=189, Percent_Identity=26.984126984127, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 29293; Mature: 29293

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIIENVIPAFIITLFAGLSTGIGSALALFARRTNTKFLSISLGFSAGVMVYVSFVELFN
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHH
GALETLIKVHGSKTGQILAVLSFFTGILIIAIIDNMVPEHENPHQVRKERELINIKKENV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
NNDFSLKKMGLLSAVAISIHNFPEGIATFASSLSDLTVGVSIAVAIAIHNIPEGVSVSVP
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
IYYATGNKKKAFIYSFMSGLSEPLGALIGYAFFKIFLSDTVLGIIFGLVAGIMVFISIDE
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPASRRYGQGHQEIYSFIAGMAVMAISLLLL
HCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MIIIENVIPAFIITLFAGLSTGIGSALALFARRTNTKFLSISLGFSAGVMVYVSFVELFN
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHH
GALETLIKVHGSKTGQILAVLSFFTGILIIAIIDNMVPEHENPHQVRKERELINIKKENV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
NNDFSLKKMGLLSAVAISIHNFPEGIATFASSLSDLTVGVSIAVAIAIHNIPEGVSVSVP
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
IYYATGNKKKAFIYSFMSGLSEPLGALIGYAFFKIFLSDTVLGIIFGLVAGIMVFISIDE
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPASRRYGQGHQEIYSFIAGMAVMAISLLLL
HCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA