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The map label for this gene is tlpB [H]

Identifier: 220931513

GI number: 220931513

Start: 726052

End: 727656

Strand: Direct

Name: tlpB [H]

Synonym: Hore_06690

Alternate gene names: 220931513

Gene position: 726052-727656 (Clockwise)

Preceding gene: 220931512

Following gene: 220931514

Centisome position: 28.16

GC content: 32.83

Gene sequence:

>1605_bases
TTGAAAGACAGATGGATTAAAGGACTTTATACCATATTTGTTCCTTTAATCATCACCGTTTTATATTTGATATTAAGTAA
TTGGAATTTAAGCAGGCTTTTACCGGTTCTTATTTATTGTATTATTTCCATAACAGGTTATTTTATATATTCTGCTTTCA
GAGGAAGTAGTTATAATATAATTGAAAGGAAACTAAAACAATTAGCCCGGGGAAGCTTTCATGTTAAATTTGAGGAAAAA
GGTTCCTTTAAAGGTATAAGTAGCTCTTTAAATAAGATATTAAAAAGATTTCGCCATTTTATAGGTACTACAGTTCAGTC
ATCAGAAAAGGTCCTCAGGGCAACCAGGGACATAAATAAGGACCTTAAATCAATCAAAATGGCTTCAGAGAATATATCTA
AAACCATGGAAAGCTTTTCAGGAAACCTTATTCAACAGAGTGAGAAGGCTGAAGATACTAATAAGGAAATGAAAAATTTA
CATAAATTTTCAGAAAAAGTTGTTGAATATTCCCAGAACACCCTTAATAGCTCCCGGAAAATGGATGAAATAATTGAAAG
TAATAGTGAAGATATCAGGGAAATTATAAATATACTGGATAATAATGTAAATAATTTCAGGAAATTATCCTCTGTTACCG
GAAAATTAAGTGCACAGGCCAACAATATAAGTGAAATAACCAGTAAGGTTAACGAGATTGCAGCCCAGACTAATTTACTT
GCATTAAATGCCAGCATTGAAGCTGCCAGAGCAGGTGAATACGGACGAGGGTTTGCTGTTGTTGCCGATGAAATTAGGGA
ACTGGCCGGACAGGTAACTGGTTTTTCCGGAGAGATAGGTGGCATTGTAAATGATATTTTAGAAGCTATTAACCAGATTA
AGGAAGAAATTAATGAGCATGCGGCTGAACTGGAAGATAATCTTAATATAATTAATAATGCAGAAGAAGCCCTGAAAAAA
ATGAAGAAATCCTCTGAAAAAAATACAGCTACATCTTTTGAAATAAAAAATATAGCAATAAAACAAAAAGAGATAGCTGA
CTCTGTTTTAAAGAAGATAGATAATATTTTAGAGACATCTCAGGAAGCAGCTGCAGCGGTTGAGGAAATATCGGCCAGTA
CTCAGGAACAAAGTTCTTATTTAAATAATACATATGATAAGATAGATAACCTGACAGATGAAATTCAGAATTTAAGTGTA
GAAACAAAAACATTTATGACCGGTTTTAAATTAACAGAGTCAGAAGAAAATATGCTAAATAATTGTTTTAAAATTATAAA
AAACCTGGCCTCACCGGACCTCCTGGATGATAATAATAGAACCAGGCAAATATTAAAGAAAGTAACTGAAGAAAACAAAC
AGTTTGATATAATCTGTGTAATGAATAGAGAAGGGCTTAATTTTTCATCGAGTATTGATGAAGAAGATATGACCACTGAT
TATTCCCATCGAAGTTATTTTGTGAAAGCAATTAATGGTAAAGACTATCGTTCCGAACCATATGTATCACTGGATACAGA
CGATTACTGTATTGCAATATCAACTCCGGTAAGAGATAAAAACGGTGAGGTGATCGGGGTAGTAATGGCAGATGTTAAAA
TATAA

Upstream 100 bases:

>100_bases
CTAACATGGGCCTGTCAGGGGCTCAATGTTTAATTTTTTGGGGGAGAATTTTTTATTAATAATGGTAATTATAGTTATAT
TTTGAAAGGGGGAAACATAG

Downstream 100 bases:

>100_bases
CATCTAATAAACACATAATTAGTGTCTTATGAGCTAAGCTAAATTGCGGAGGTGTTTACCTTTGCAAAAAAATAAATCAC
CAGAGACTACCAGCTGGGTA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MKDRWIKGLYTIFVPLIITVLYLILSNWNLSRLLPVLIYCIISITGYFIYSAFRGSSYNIIERKLKQLARGSFHVKFEEK
GSFKGISSSLNKILKRFRHFIGTTVQSSEKVLRATRDINKDLKSIKMASENISKTMESFSGNLIQQSEKAEDTNKEMKNL
HKFSEKVVEYSQNTLNSSRKMDEIIESNSEDIREIINILDNNVNNFRKLSSVTGKLSAQANNISEITSKVNEIAAQTNLL
ALNASIEAARAGEYGRGFAVVADEIRELAGQVTGFSGEIGGIVNDILEAINQIKEEINEHAAELEDNLNIINNAEEALKK
MKKSSEKNTATSFEIKNIAIKQKEIADSVLKKIDNILETSQEAAAAVEEISASTQEQSSYLNNTYDKIDNLTDEIQNLSV
ETKTFMTGFKLTESEENMLNNCFKIIKNLASPDLLDDNNRTRQILKKVTEENKQFDIICVMNREGLNFSSSIDEEDMTTD
YSHRSYFVKAINGKDYRSEPYVSLDTDDYCIAISTPVRDKNGEVIGVVMADVKI

Sequences:

>Translated_534_residues
MKDRWIKGLYTIFVPLIITVLYLILSNWNLSRLLPVLIYCIISITGYFIYSAFRGSSYNIIERKLKQLARGSFHVKFEEK
GSFKGISSSLNKILKRFRHFIGTTVQSSEKVLRATRDINKDLKSIKMASENISKTMESFSGNLIQQSEKAEDTNKEMKNL
HKFSEKVVEYSQNTLNSSRKMDEIIESNSEDIREIINILDNNVNNFRKLSSVTGKLSAQANNISEITSKVNEIAAQTNLL
ALNASIEAARAGEYGRGFAVVADEIRELAGQVTGFSGEIGGIVNDILEAINQIKEEINEHAAELEDNLNIINNAEEALKK
MKKSSEKNTATSFEIKNIAIKQKEIADSVLKKIDNILETSQEAAAAVEEISASTQEQSSYLNNTYDKIDNLTDEIQNLSV
ETKTFMTGFKLTESEENMLNNCFKIIKNLASPDLLDDNNRTRQILKKVTEENKQFDIICVMNREGLNFSSSIDEEDMTTD
YSHRSYFVKAINGKDYRSEPYVSLDTDDYCIAISTPVRDKNGEVIGVVMADVKI
>Mature_534_residues
MKDRWIKGLYTIFVPLIITVLYLILSNWNLSRLLPVLIYCIISITGYFIYSAFRGSSYNIIERKLKQLARGSFHVKFEEK
GSFKGISSSLNKILKRFRHFIGTTVQSSEKVLRATRDINKDLKSIKMASENISKTMESFSGNLIQQSEKAEDTNKEMKNL
HKFSEKVVEYSQNTLNSSRKMDEIIESNSEDIREIINILDNNVNNFRKLSSVTGKLSAQANNISEITSKVNEIAAQTNLL
ALNASIEAARAGEYGRGFAVVADEIRELAGQVTGFSGEIGGIVNDILEAINQIKEEINEHAAELEDNLNIINNAEEALKK
MKKSSEKNTATSFEIKNIAIKQKEIADSVLKKIDNILETSQEAAAAVEEISASTQEQSSYLNNTYDKIDNLTDEIQNLSV
ETKTFMTGFKLTESEENMLNNCFKIIKNLASPDLLDDNNRTRQILKKVTEENKQFDIICVMNREGLNFSSSIDEEDMTTD
YSHRSYFVKAINGKDYRSEPYVSLDTDDYCIAISTPVRDKNGEVIGVVMADVKI

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=297, Percent_Identity=26.9360269360269, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI2367378, Length=258, Percent_Identity=28.6821705426357, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1789453, Length=391, Percent_Identity=22.2506393861893, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788194, Length=172, Percent_Identity=30.8139534883721, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788195, Length=258, Percent_Identity=26.3565891472868, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60201; Mature: 60201

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDRWIKGLYTIFVPLIITVLYLILSNWNLSRLLPVLIYCIISITGYFIYSAFRGSSYNI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IERKLKQLARGSFHVKFEEKGSFKGISSSLNKILKRFRHFIGTTVQSSEKVLRATRDINK
HHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DLKSIKMASENISKTMESFSGNLIQQSEKAEDTNKEMKNLHKFSEKVVEYSQNTLNSSRK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDEIIESNSEDIREIINILDNNVNNFRKLSSVTGKLSAQANNISEITSKVNEIAAQTNLL
HHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCEE
ALNASIEAARAGEYGRGFAVVADEIRELAGQVTGFSGEIGGIVNDILEAINQIKEEINEH
EEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAELEDNLNIINNAEEALKKMKKSSEKNTATSFEIKNIAIKQKEIADSVLKKIDNILETS
HHHHHHCCHHHCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
QEAAAAVEEISASTQEQSSYLNNTYDKIDNLTDEIQNLSVETKTFMTGFKLTESEENMLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHH
NCFKIIKNLASPDLLDDNNRTRQILKKVTEENKQFDIICVMNREGLNFSSSIDEEDMTTD
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHCCCC
YSHRSYFVKAINGKDYRSEPYVSLDTDDYCIAISTPVRDKNGEVIGVVMADVKI
CCCHHEEEEEECCCCCCCCCCEEECCCCEEEEEECCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MKDRWIKGLYTIFVPLIITVLYLILSNWNLSRLLPVLIYCIISITGYFIYSAFRGSSYNI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IERKLKQLARGSFHVKFEEKGSFKGISSSLNKILKRFRHFIGTTVQSSEKVLRATRDINK
HHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DLKSIKMASENISKTMESFSGNLIQQSEKAEDTNKEMKNLHKFSEKVVEYSQNTLNSSRK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDEIIESNSEDIREIINILDNNVNNFRKLSSVTGKLSAQANNISEITSKVNEIAAQTNLL
HHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCEE
ALNASIEAARAGEYGRGFAVVADEIRELAGQVTGFSGEIGGIVNDILEAINQIKEEINEH
EEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAELEDNLNIINNAEEALKKMKKSSEKNTATSFEIKNIAIKQKEIADSVLKKIDNILETS
HHHHHHCCHHHCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
QEAAAAVEEISASTQEQSSYLNNTYDKIDNLTDEIQNLSVETKTFMTGFKLTESEENMLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHH
NCFKIIKNLASPDLLDDNNRTRQILKKVTEENKQFDIICVMNREGLNFSSSIDEEDMTTD
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHCCCC
YSHRSYFVKAINGKDYRSEPYVSLDTDDYCIAISTPVRDKNGEVIGVVMADVKI
CCCHHEEEEEECCCCCCCCCCEEECCCCEEEEEECCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]