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The map label for this gene is arcD [H]

Identifier: 220931511

GI number: 220931511

Start: 723275

End: 724717

Strand: Direct

Name: arcD [H]

Synonym: Hore_06670

Alternate gene names: 220931511

Gene position: 723275-724717 (Clockwise)

Preceding gene: 220931510

Following gene: 220931512

Centisome position: 28.05

GC content: 42.13

Gene sequence:

>1443_bases
ATGGAAAAGGCAAAAGAAAAATTAGGATTTTGGGCTCTGGCTGGTTTAATAGTTGGATCTATGATAGGTGGTGGGGCATT
CAACCTACCCTCCGATATGGCCTCCGGGGCTGGTTCCGGTGCAGTCCTTTTAGGTTGGCTGGTAACCGGTATTGGTATGA
TTGCCCTGGCATTATCCTATCAAAATTTATCTATGCGCAAACCTGATCTCGATGGTGGAATTTACAGTTATGCCAAGGGC
GGTTTTGGTGAATACATGGGATTCAATTCGGCCTGGGGTTACTGGCTGTCCGCCTGGTTAGGTAATGTTGCCTATGCAAC
TTTCTTATTTGGAACACTTAGTTATTTTATTCCTGCTTTCAATAATGATGGAAATAACTGGCCGTCTGTTATTGCTGCAT
CTCTCCTGATACTGGCAATAAACTACCTGATCCTGAGGGGTGTTAAGGAAGCCAGTCTGGTAAACCTGGTAACAACCATC
GCTAAAATAATTCCTATTGCAATTTTCATAATCATTGGATTATTTGCCTTTAAAGCAGACCTCTTTAGCCGTGATATGTT
TGAAGTAATCAAACTTGCCGGTGAAAGTGGCACTCAGAGTGTAGGTCTTTTTGAACAGGTAACAAACACCTTAATGGTAA
CCCTCTGGGTTTTCATTGGTGTTGAAGGTGCTGTTGTTGTTTCTGGTCGCGCCAAAAAGAGAAGTGATATTGGTAAGGCT
ACAGTAATGGGACTGCTGGGAACACTTGTTATTTATGTTCTGATAACAACTGTTTCCTATGGTATTATGCCCAGGGCTGA
ACTGGCCGGTTTAAGCAAACCTACTATGGCCGGTGTTCTAGAAGCTGTAGTTGGCCCGTGGGGTGCTGTTCTGGTAAGAA
TGGGACTTGGCATTTCATTACTGGGAGCTACTTTAGGTTGGACTTTACTGGCTGCTGAAATTCCTTATGTTGCAGCTAAA
GATGGAGTATTCCCCAGACTTTTTGCCCGCGAAAATGAAAATGGTTCACCTGCAGCGTCTCTGTGGATTACTAACCTGTT
AGTAATAGGTTTTATTATATACTCCCATTTCTCAATGAGTTCTTATGTGGCTATTTATTACATGGCCGGTACAGCTATTA
TCCTTCCATATTTATTCTCAGCCCTGTACCAGCTTAAGCTTGTCTTAACAGGTGAAGGGTATAAAGCAGATGAAAATAAA
ACCGGTGATTTGATTAAGGGTATTATTGCTACCATATACTCAGCCTGGTTAGTTTATGCCGCCGGAATGAGTTATCTCCT
GATGGTATCTGTACTCTATGCACCTGGTTTTATTTTCTATCTAATGTCCAGAAAAGAACAAGGAAAGAAAGCTAAAACAT
CTGACTGGGTTCTGGCACTAATTATTGCTGGCTTTGCTGTCTATGCAATTGTCTTAATGGCTCAGGGAGTTATTGCACCA
TAA

Upstream 100 bases:

>100_bases
GTTAACATTAATAATTAAATTAAGGCCAGTACTATTATTTTAATTTAGGCTAGTATTACTACTAGTATTTATCTATAAAT
TTAAACAAAGGGGTGTTAAG

Downstream 100 bases:

>100_bases
AACAGGTTTGTTGTTATAATTTTCGAACCAGTTCTATACCCTAAATTCATAGCTTTAATTGTCCTAATCTGTAGCATTTG
ATCTCAGGGCTTAAACAAAT

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MEKAKEKLGFWALAGLIVGSMIGGGAFNLPSDMASGAGSGAVLLGWLVTGIGMIALALSYQNLSMRKPDLDGGIYSYAKG
GFGEYMGFNSAWGYWLSAWLGNVAYATFLFGTLSYFIPAFNNDGNNWPSVIAASLLILAINYLILRGVKEASLVNLVTTI
AKIIPIAIFIIIGLFAFKADLFSRDMFEVIKLAGESGTQSVGLFEQVTNTLMVTLWVFIGVEGAVVVSGRAKKRSDIGKA
TVMGLLGTLVIYVLITTVSYGIMPRAELAGLSKPTMAGVLEAVVGPWGAVLVRMGLGISLLGATLGWTLLAAEIPYVAAK
DGVFPRLFARENENGSPAASLWITNLLVIGFIIYSHFSMSSYVAIYYMAGTAIILPYLFSALYQLKLVLTGEGYKADENK
TGDLIKGIIATIYSAWLVYAAGMSYLLMVSVLYAPGFIFYLMSRKEQGKKAKTSDWVLALIIAGFAVYAIVLMAQGVIAP

Sequences:

>Translated_480_residues
MEKAKEKLGFWALAGLIVGSMIGGGAFNLPSDMASGAGSGAVLLGWLVTGIGMIALALSYQNLSMRKPDLDGGIYSYAKG
GFGEYMGFNSAWGYWLSAWLGNVAYATFLFGTLSYFIPAFNNDGNNWPSVIAASLLILAINYLILRGVKEASLVNLVTTI
AKIIPIAIFIIIGLFAFKADLFSRDMFEVIKLAGESGTQSVGLFEQVTNTLMVTLWVFIGVEGAVVVSGRAKKRSDIGKA
TVMGLLGTLVIYVLITTVSYGIMPRAELAGLSKPTMAGVLEAVVGPWGAVLVRMGLGISLLGATLGWTLLAAEIPYVAAK
DGVFPRLFARENENGSPAASLWITNLLVIGFIIYSHFSMSSYVAIYYMAGTAIILPYLFSALYQLKLVLTGEGYKADENK
TGDLIKGIIATIYSAWLVYAAGMSYLLMVSVLYAPGFIFYLMSRKEQGKKAKTSDWVLALIIAGFAVYAIVLMAQGVIAP
>Mature_480_residues
MEKAKEKLGFWALAGLIVGSMIGGGAFNLPSDMASGAGSGAVLLGWLVTGIGMIALALSYQNLSMRKPDLDGGIYSYAKG
GFGEYMGFNSAWGYWLSAWLGNVAYATFLFGTLSYFIPAFNNDGNNWPSVIAASLLILAINYLILRGVKEASLVNLVTTI
AKIIPIAIFIIIGLFAFKADLFSRDMFEVIKLAGESGTQSVGLFEQVTNTLMVTLWVFIGVEGAVVVSGRAKKRSDIGKA
TVMGLLGTLVIYVLITTVSYGIMPRAELAGLSKPTMAGVLEAVVGPWGAVLVRMGLGISLLGATLGWTLLAAEIPYVAAK
DGVFPRLFARENENGSPAASLWITNLLVIGFIIYSHFSMSSYVAIYYMAGTAIILPYLFSALYQLKLVLTGEGYKADENK
TGDLIKGIIATIYSAWLVYAAGMSYLLMVSVLYAPGFIFYLMSRKEQGKKAKTSDWVLALIIAGFAVYAIVLMAQGVIAP

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=447, Percent_Identity=43.1767337807606, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI2367353, Length=431, Percent_Identity=31.0904872389791, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1790575, Length=342, Percent_Identity=26.6081871345029, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786908, Length=467, Percent_Identity=25.2676659528908, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87082250, Length=365, Percent_Identity=26.5753424657534, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51316; Mature: 51316

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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>Mature Secondary Structure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PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9053381; 11792842 [H]