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The map label for this gene is infC [H]

Identifier: 220931403

GI number: 220931403

Start: 609745

End: 610125

Strand: Direct

Name: infC [H]

Synonym: Hore_05590

Alternate gene names: 220931403

Gene position: 609745-610125 (Clockwise)

Preceding gene: 220931402

Following gene: 220931404

Centisome position: 23.65

GC content: 38.06

Gene sequence:

>381_bases
GTGGAAGTAGCTCCTCAGGCCAGACCACCTGTATGTAAAATCATGGACTATGGGAAGTATAAATATGAACAGGCCAAAAA
AGCCAAAGAAGCTAAAAAGAAACAAAATGTAATGAATGTTAAGGAAGTCCAGATGGGAGTAAAAATCGAAGACCATGATT
TTAACGTTAAGGCTAAAATGGCTAAAAGGTTTCTGAAAAATAAGCATAAAGTAAAAGTAAGAATTCGTTTCAGGGGCCGG
GAGGTAATGCACAAACAGTTAGGTTATGACCTGATGAACAGATTGATCGATGAAGTAAAAGATCTGGGAGTAGTGGAAAG
CAAGCCCAAAATGGAAGGCCGCAACATGATCATGGTATTGACTCCAATTAGTGATAAATAA

Upstream 100 bases:

>100_bases
GGCTAGAAAAGTTAGAGTAATTAACCCAGATGGAGAACAAATAGGTATTAAACCAATCCAGGAGGCACTGAGAATTTCCC
AGGATAAGGGACTGGATTTA

Downstream 100 bases:

>100_bases
GGAGGGATAAATATGCCTAAGCTTAAAACCCATAAGGGTATTGCCAAGAGAATAAAGAAAACCGGCAAAGGGAAACTTAA
ACGTAATAAGGCTTATCATA

Product: initiation factor 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MEVAPQARPPVCKIMDYGKYKYEQAKKAKEAKKKQNVMNVKEVQMGVKIEDHDFNVKAKMAKRFLKNKHKVKVRIRFRGR
EVMHKQLGYDLMNRLIDEVKDLGVVESKPKMEGRNMIMVLTPISDK

Sequences:

>Translated_126_residues
MEVAPQARPPVCKIMDYGKYKYEQAKKAKEAKKKQNVMNVKEVQMGVKIEDHDFNVKAKMAKRFLKNKHKVKVRIRFRGR
EVMHKQLGYDLMNRLIDEVKDLGVVESKPKMEGRNMIMVLTPISDK
>Mature_126_residues
MEVAPQARPPVCKIMDYGKYKYEQAKKAKEAKKKQNVMNVKEVQMGVKIEDHDFNVKAKMAKRFLKNKHKVKVRIRFRGR
EVMHKQLGYDLMNRLIDEVKDLGVVESKPKMEGRNMIMVLTPISDK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=123, Percent_Identity=50.4065040650407, Blast_Score=115, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 14776; Mature: 14776

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
7.9 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
7.9 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVAPQARPPVCKIMDYGKYKYEQAKKAKEAKKKQNVMNVKEVQMGVKIEDHDFNVKAKM
CCCCCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEECCCCCCHHHH
AKRFLKNKHKVKVRIRFRGREVMHKQLGYDLMNRLIDEVKDLGVVESKPKMEGRNMIMVL
HHHHHCCCCEEEEEEEECCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
TPISDK
ECCCCC
>Mature Secondary Structure
MEVAPQARPPVCKIMDYGKYKYEQAKKAKEAKKKQNVMNVKEVQMGVKIEDHDFNVKAKM
CCCCCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEECCCCCCHHHH
AKRFLKNKHKVKVRIRFRGREVMHKQLGYDLMNRLIDEVKDLGVVESKPKMEGRNMIMVL
HHHHHCCCCEEEEEEEECCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
TPISDK
ECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]