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The map label for this gene is appB [H]

Identifier: 220931336

GI number: 220931336

Start: 533547

End: 534578

Strand: Direct

Name: appB [H]

Synonym: Hore_04910

Alternate gene names: 220931336

Gene position: 533547-534578 (Clockwise)

Preceding gene: 220931335

Following gene: 220931337

Centisome position: 20.69

GC content: 42.83

Gene sequence:

>1032_bases
TTGACTAGTTATATTATAAGGCGTTTACTCATATTGCCTATTATTCTATTAGGGGTTACTCTTCTGATCTTTTCAATGAT
AATGTGCTTAAGTCCCTATCAGAGGGTAGCCAACTATGTTACTGATCCGACCCAGCTGAAGGGTGGGGATATAGATTTAC
TTGTAAAGAAATATGGTCTTGATGATCCCTGGTATCAACAGTATGGAAGATGGCTGAATAATTTAATTCATGGTGATTTA
GGCTGGTCTGAGGCTGCCGGTGCTCCGGTTACTCAGGCTATAAAAGAGAGATTTCCAGCTACAGTTGAACTGGCTATTCT
GGCAGTAATTCCAGTTGTTATGGGGGGGATCTGGCTCGGGGTGTTCTCGGCGGTTCATCATAATGATATCTGGGACCATA
TTACCCGGGTCTTTGCGATTATAGGATGGTCATTTCCAACCTTTGTTTTTGGTCTATATATATTAATGTTTTTCTATGGT
GTTCTCGGTTGGACTCCACCCGGCCGGTTAAGTAGCTGGGCTATGGAACTGGCTAATACTTCAGAGTTTGTAAGGTATAC
AGGTTTAAATATTCTGGATGGTATTCTTAATGGAAATCTGGCCTTTGTGTGGGATGCTGTCCGTCACCTCATTGCTCCAG
TATTGACCCTGGCAGTTGTCTGGTGGGCTTATATCTTGAGGATTACCAGATCAAGTATGCTGGAAACATTAAGGAAGGAT
TATATCAGGACTGCCCGGGCTAAAGGTGTCAAGGAAAATGTTGTTATTCAAAAGCATGCCCGCAGGAATGCCTTGATACC
GGTTGTTACTGTAGCAGGACCCATGGTTCTGGGATTACTGGGTGGTATTGTTACTGTGGAGACAGTTTTTGGCTACCGGG
GTTTAGGACTCCTTGCTTATGAAACTGCTACCAGGTTAGACCATACCGGGATTCTGGGTGTTGCTATGTACTTTGGTCTG
TTACTTATTCTCATTAACCTAGCTGTCGATGTTTCTTATGCTATTATAGATCCAAGAATAAGATTGGAGTGA

Upstream 100 bases:

>100_bases
ATGTATTAAATTGAATATGTATTAATATTTAATCTTGTTTAATTATGTTAAAGTATTAATTGGTTGAAATAAATCCAGTA
AAGAAAGGAGTTGTAGCAGA

Downstream 100 bases:

>100_bases
TGAAAGATGACATGGCAAGAGCTCTTTAAGCGTTTATTAAAAAATAAATTATCTTTGTTTGGGTTAATCATTATAGTATT
TTTTGCTCTGATTGCTATAT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTSYIIRRLLILPIILLGVTLLIFSMIMCLSPYQRVANYVTDPTQLKGGDIDLLVKKYGLDDPWYQQYGRWLNNLIHGDL
GWSEAAGAPVTQAIKERFPATVELAILAVIPVVMGGIWLGVFSAVHHNDIWDHITRVFAIIGWSFPTFVFGLYILMFFYG
VLGWTPPGRLSSWAMELANTSEFVRYTGLNILDGILNGNLAFVWDAVRHLIAPVLTLAVVWWAYILRITRSSMLETLRKD
YIRTARAKGVKENVVIQKHARRNALIPVVTVAGPMVLGLLGGIVTVETVFGYRGLGLLAYETATRLDHTGILGVAMYFGL
LLILINLAVDVSYAIIDPRIRLE

Sequences:

>Translated_343_residues
MTSYIIRRLLILPIILLGVTLLIFSMIMCLSPYQRVANYVTDPTQLKGGDIDLLVKKYGLDDPWYQQYGRWLNNLIHGDL
GWSEAAGAPVTQAIKERFPATVELAILAVIPVVMGGIWLGVFSAVHHNDIWDHITRVFAIIGWSFPTFVFGLYILMFFYG
VLGWTPPGRLSSWAMELANTSEFVRYTGLNILDGILNGNLAFVWDAVRHLIAPVLTLAVVWWAYILRITRSSMLETLRKD
YIRTARAKGVKENVVIQKHARRNALIPVVTVAGPMVLGLLGGIVTVETVFGYRGLGLLAYETATRLDHTGILGVAMYFGL
LLILINLAVDVSYAIIDPRIRLE
>Mature_342_residues
TSYIIRRLLILPIILLGVTLLIFSMIMCLSPYQRVANYVTDPTQLKGGDIDLLVKKYGLDDPWYQQYGRWLNNLIHGDLG
WSEAAGAPVTQAIKERFPATVELAILAVIPVVMGGIWLGVFSAVHHNDIWDHITRVFAIIGWSFPTFVFGLYILMFFYGV
LGWTPPGRLSSWAMELANTSEFVRYTGLNILDGILNGNLAFVWDAVRHLIAPVLTLAVVWWAYILRITRSSMLETLRKDY
IRTARAKGVKENVVIQKHARRNALIPVVTVAGPMVLGLLGGIVTVETVFGYRGLGLLAYETATRLDHTGILGVAMYFGLL
LILINLAVDVSYAIIDPRIRLE

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=349, Percent_Identity=36.3896848137536, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1787053, Length=349, Percent_Identity=35.243553008596, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787761, Length=306, Percent_Identity=40.8496732026144, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1787497, Length=343, Percent_Identity=32.3615160349854, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1789888, Length=346, Percent_Identity=28.0346820809249, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1788504, Length=297, Percent_Identity=29.6296296296296, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=30.5147058823529, Blast_Score=128, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38343; Mature: 38212

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYIIRRLLILPIILLGVTLLIFSMIMCLSPYQRVANYVTDPTQLKGGDIDLLVKKYGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHCC
DDPWYQQYGRWLNNLIHGDLGWSEAAGAPVTQAIKERFPATVELAILAVIPVVMGGIWLG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VFSAVHHNDIWDHITRVFAIIGWSFPTFVFGLYILMFFYGVLGWTPPGRLSSWAMELANT
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SEFVRYTGLNILDGILNGNLAFVWDAVRHLIAPVLTLAVVWWAYILRITRSSMLETLRKD
HHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIRTARAKGVKENVVIQKHARRNALIPVVTVAGPMVLGLLGGIVTVETVFGYRGLGLLAY
HHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ETATRLDHTGILGVAMYFGLLLILINLAVDVSYAIIDPRIRLE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEECC
>Mature Secondary Structure 
TSYIIRRLLILPIILLGVTLLIFSMIMCLSPYQRVANYVTDPTQLKGGDIDLLVKKYGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHCC
DDPWYQQYGRWLNNLIHGDLGWSEAAGAPVTQAIKERFPATVELAILAVIPVVMGGIWLG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VFSAVHHNDIWDHITRVFAIIGWSFPTFVFGLYILMFFYGVLGWTPPGRLSSWAMELANT
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SEFVRYTGLNILDGILNGNLAFVWDAVRHLIAPVLTLAVVWWAYILRITRSSMLETLRKD
HHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIRTARAKGVKENVVIQKHARRNALIPVVTVAGPMVLGLLGGIVTVETVFGYRGLGLLAY
HHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ETATRLDHTGILGVAMYFGLLLILINLAVDVSYAIIDPRIRLE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]