Click here to switch to the map view.

The map label for this gene is hsdM [C]

Identifier: 220931289

GI number: 220931289

Start: 477040

End: 478527

Strand: Direct

Name: hsdM [C]

Synonym: Hore_04440

Alternate gene names: 220931289

Gene position: 477040-478527 (Clockwise)

Preceding gene: 220931287

Following gene: 220931290

Centisome position: 18.5

GC content: 35.69

Gene sequence:

>1488_bases
ATGTCACAGGAAACACTAACACTTGATAAACTGGAATCTCATCTCTGGGAATCAGCAAACATTTTGAGGGGAAGCATTGA
TTCTTCTGATTATAAAAATTATATCTTTGGTATGTTATTTTTAAAAAGAATAAGTGATGTATTTGATGAAGAATGTGAAA
AGATGAAAGCTGAAGGGAAAGAAGCTTTTATTGATGACCCTGATTTTCATGACTTTTTTGTACCAAAAAGAGCCAGATGG
GAGCATATTAGTAAGGTTACACAGGATATAGGTTCTCATATTAACAAGGCATTCGAAGTCTTAGAAGAACACAATAAAAT
GCTGGAGGGTGTTTTAGCTCCGATAGACTTTAATGATAAAGAGAGATTACCTGACCATGTACTTGAAGAGTTAATACAGC
ATTTTTCTAAGTACAGTTTGAAAAATAGAGATCTTGAAGATCCTGATATTCTTGGAAGGGCATATGAATATTTGATTCGT
CAATTTGCAGATGATGCTGGTAAAAAAGGGGGAGAATTTTATACTCCCCGACAGGTAGTCAAATTGCTCGTGGAAATCCT
GGATCCTCGACCAGGGATGAGTGTTTATGACCCCTGTTGTGGTTCTGGGGGTATGTTAATCTATTCCGCTGAACATTTAA
TAGAAGAAGGCAATGATATATCTGAAATATCACTGTACGGTCAGGAAAGAAATTTAAACACCTGGGCTATCTGTAAAATG
AACATGCTCCTGCATGGGCTTTATGATGCTAAAATAGCCAAGGGAGATACCATGCGCGACCCACAGTTTCTTGATAACGG
TAAGTTAGACCAGTTTGATAGAGTTATTGCCAATCCCATGTGGAATCAGAGCTCATGGAGCAAAAAATATCTGCAAGAGA
CTGAGCCTTTTGGCAGGTTTAGCTATGGTTTTCCTCCTAAAAATTCTGCAGACTGGGTCTGGATTCAGCATATGCTTGCA
AGTGCCAACAAAAAGGGTAAAATTGGTGTAGTATTAGATAATGGTGTGTTATTTAGAGGCAGGTCAGAAGGTAAAATTAG
AAAGAAAGTTCTAAAGCATGATTTGATTGAAGCTGTTATTGCTTTACCTTCAAACTTATTCTATAATACATCATCTCCTG
GATGTATTTTGATATTAAATAAGGATAAGACTGTTGAGAGAAAAAATAAGGTAATTTTCATATATGCTGAAGAAGATTAC
AAGGAAGGAAGTAATCAAAACTACCTGAGAGAGAAAGATATTGAAAAAATATTAAATGCTTACAAAAACTTTGAAGATAT
TGAAAGGTATTGCAGGGTAGTCGATATGGAAGAGATTGAACGAAATGATTATAACCTGAATGTCCCCAGATATGTAGATA
CTACAGAACCTGAAGAACCCATTGATGTGCAAGAGGTTATTGATAATTTAAATAAGCTTGAAGAGGAACGGAAGGAAATT
GAAGAAGAAATGAATGGATATTTGAGAGAGTTGGGATATGATGATTAA

Upstream 100 bases:

>100_bases
AATTAATATATTAAATATACAAATATTAGCATGTTTAATTTACAAAAATGTGGTCAGGACTAAATTGCTTTATATGTAAG
CATTTATGGGAGGGAGAAAA

Downstream 100 bases:

>100_bases
GGACGGGTATAAGGAAGTAAGAATAGGACCCAAAAAATATCATATTCCAAAAGAATGGGAGTTTAGAAATTTTGGTTTGA
TTTCCAAATATATTAAAGCA

Product: type I restriction-modification system, M subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSQETLTLDKLESHLWESANILRGSIDSSDYKNYIFGMLFLKRISDVFDEECEKMKAEGKEAFIDDPDFHDFFVPKRARW
EHISKVTQDIGSHINKAFEVLEEHNKMLEGVLAPIDFNDKERLPDHVLEELIQHFSKYSLKNRDLEDPDILGRAYEYLIR
QFADDAGKKGGEFYTPRQVVKLLVEILDPRPGMSVYDPCCGSGGMLIYSAEHLIEEGNDISEISLYGQERNLNTWAICKM
NMLLHGLYDAKIAKGDTMRDPQFLDNGKLDQFDRVIANPMWNQSSWSKKYLQETEPFGRFSYGFPPKNSADWVWIQHMLA
SANKKGKIGVVLDNGVLFRGRSEGKIRKKVLKHDLIEAVIALPSNLFYNTSSPGCILILNKDKTVERKNKVIFIYAEEDY
KEGSNQNYLREKDIEKILNAYKNFEDIERYCRVVDMEEIERNDYNLNVPRYVDTTEPEEPIDVQEVIDNLNKLEEERKEI
EEEMNGYLRELGYDD

Sequences:

>Translated_495_residues
MSQETLTLDKLESHLWESANILRGSIDSSDYKNYIFGMLFLKRISDVFDEECEKMKAEGKEAFIDDPDFHDFFVPKRARW
EHISKVTQDIGSHINKAFEVLEEHNKMLEGVLAPIDFNDKERLPDHVLEELIQHFSKYSLKNRDLEDPDILGRAYEYLIR
QFADDAGKKGGEFYTPRQVVKLLVEILDPRPGMSVYDPCCGSGGMLIYSAEHLIEEGNDISEISLYGQERNLNTWAICKM
NMLLHGLYDAKIAKGDTMRDPQFLDNGKLDQFDRVIANPMWNQSSWSKKYLQETEPFGRFSYGFPPKNSADWVWIQHMLA
SANKKGKIGVVLDNGVLFRGRSEGKIRKKVLKHDLIEAVIALPSNLFYNTSSPGCILILNKDKTVERKNKVIFIYAEEDY
KEGSNQNYLREKDIEKILNAYKNFEDIERYCRVVDMEEIERNDYNLNVPRYVDTTEPEEPIDVQEVIDNLNKLEEERKEI
EEEMNGYLRELGYDD
>Mature_494_residues
SQETLTLDKLESHLWESANILRGSIDSSDYKNYIFGMLFLKRISDVFDEECEKMKAEGKEAFIDDPDFHDFFVPKRARWE
HISKVTQDIGSHINKAFEVLEEHNKMLEGVLAPIDFNDKERLPDHVLEELIQHFSKYSLKNRDLEDPDILGRAYEYLIRQ
FADDAGKKGGEFYTPRQVVKLLVEILDPRPGMSVYDPCCGSGGMLIYSAEHLIEEGNDISEISLYGQERNLNTWAICKMN
MLLHGLYDAKIAKGDTMRDPQFLDNGKLDQFDRVIANPMWNQSSWSKKYLQETEPFGRFSYGFPPKNSADWVWIQHMLAS
ANKKGKIGVVLDNGVLFRGRSEGKIRKKVLKHDLIEAVIALPSNLFYNTSSPGCILILNKDKTVERKNKVIFIYAEEDYK
EGSNQNYLREKDIEKILNAYKNFEDIERYCRVVDMEEIERNDYNLNVPRYVDTTEPEEPIDVQEVIDNLNKLEEERKEIE
EEMNGYLRELGYDD

Specific function: The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=396, Percent_Identity=22.979797979798, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR011991 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 57602; Mature: 57471

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQETLTLDKLESHLWESANILRGSIDSSDYKNYIFGMLFLKRISDVFDEECEKMKAEGK
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EAFIDDPDFHDFFVPKRARWEHISKVTQDIGSHINKAFEVLEEHNKMLEGVLAPIDFNDK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
ERLPDHVLEELIQHFSKYSLKNRDLEDPDILGRAYEYLIRQFADDAGKKGGEFYTPRQVV
HCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KLLVEILDPRPGMSVYDPCCGSGGMLIYSAEHLIEEGNDISEISLYGQERNLNTWAICKM
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCCCCEEEECCCCCCCCHHHHHH
NMLLHGLYDAKIAKGDTMRDPQFLDNGKLDQFDRVIANPMWNQSSWSKKYLQETEPFGRF
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC
SYGFPPKNSADWVWIQHMLASANKKGKIGVVLDNGVLFRGRSEGKIRKKVLKHDLIEAVI
CCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHH
ALPSNLFYNTSSPGCILILNKDKTVERKNKVIFIYAEEDYKEGSNQNYLREKDIEKILNA
HCCCCCEECCCCCCEEEEECCCCCHHCCCCEEEEEECCHHCCCCCCCCHHHHHHHHHHHH
YKNFEDIERYCRVVDMEEIERNDYNLNVPRYVDTTEPEEPIDVQEVIDNLNKLEEERKEI
HHCHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EEEMNGYLRELGYDD
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQETLTLDKLESHLWESANILRGSIDSSDYKNYIFGMLFLKRISDVFDEECEKMKAEGK
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EAFIDDPDFHDFFVPKRARWEHISKVTQDIGSHINKAFEVLEEHNKMLEGVLAPIDFNDK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
ERLPDHVLEELIQHFSKYSLKNRDLEDPDILGRAYEYLIRQFADDAGKKGGEFYTPRQVV
HCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KLLVEILDPRPGMSVYDPCCGSGGMLIYSAEHLIEEGNDISEISLYGQERNLNTWAICKM
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCCCCEEEECCCCCCCCHHHHHH
NMLLHGLYDAKIAKGDTMRDPQFLDNGKLDQFDRVIANPMWNQSSWSKKYLQETEPFGRF
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC
SYGFPPKNSADWVWIQHMLASANKKGKIGVVLDNGVLFRGRSEGKIRKKVLKHDLIEAVI
CCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHH
ALPSNLFYNTSSPGCILILNKDKTVERKNKVIFIYAEEDYKEGSNQNYLREKDIEKILNA
HCCCCCEECCCCCCEEEEECCCCCHHCCCCEEEEEECCHHCCCCCCCCHHHHHHHHHHHH
YKNFEDIERYCRVVDMEEIERNDYNLNVPRYVDTTEPEEPIDVQEVIDNLNKLEEERKEI
HHCHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EEEMNGYLRELGYDD
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]