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The map label for this gene is yhcK [H]

Identifier: 220931247

GI number: 220931247

Start: 410301

End: 411971

Strand: Direct

Name: yhcK [H]

Synonym: Hore_04010

Alternate gene names: 220931247

Gene position: 410301-411971 (Clockwise)

Preceding gene: 220931246

Following gene: 220931248

Centisome position: 15.91

GC content: 33.81

Gene sequence:

>1671_bases
GTGAAATTTAAAAAAGGTTACTTGTGTACATATTTAACAATTTTTGTTGTAGTAACCGGTTTTATGTTTTTAATTAATAT
TCAAACCACCCGACTCCTCAGTAATGACAAGATTTATAAAATTGTTAATTATAGTTTAGATGGTAGTTCCGATGATTTAC
ATTATCGTTTGCTGGAAGAAGGACAGCGCCTTTTCAAATTTAAGACAATTATCCCTGAATCAAAACTGCCAGCAACACTG
GATGGAAACTATAAAATTATTATTCATCGTCTGGCTGGTCAGTGGTATCGTGTTTATATAAATGATGTCTTAATAGGGAG
CCTGGGTGACATCAAAAAAGGATACAGCAATATCTGGAATGCTTTTGGTGTTTATGACCTTGATCAGGATTTGTTACAGG
AAAGAAATGAATTAGTGATAGAAGTATATGGGCTCTATGAAGTTGGTTTATTGGGTTATCCTGTTATGATAACTGATAAT
GTGACCGCCAACAGGTTATCAAACTGGTTTATAATATTAATTCGTAACATAAAACTAGTTGCCATCGGTGTTTTGTTAAC
AGCATTTATTATATTAATTCTTCTTATAAAAATGTCTAAAAAAATAAAAAGGGAATACGTCTACTATGCTCTGGGGGCTT
TTACAATTATTTTTATGGTCCTGGATTACCAGGTTATGTACAGGCTACCTGTTCCCCCTATTTTATTTAAAAAGTTTATT
ATATCAGGTATTTATCTGGCCAGTTTCTTTATTTCGATTGGTTTATATAAGCAATTTAAGGTTCAATTAAATCTGGTTCT
GGGATTAATGGTACTGGGCAGTGCAGGTTATCTTATTATCTTTCCCGGGAATATGGTAGATTTTAAGAAGTCTTATAGCT
TATTAAATCTTTTAATTTCTTTAAATGTCCTGGGATGGTTTTATGCCGGGGCTTTAAATTTTAAAAAGTCCCTCTATGCC
CGGGTTTTTTCTATCTGCAGTTTTGTTTTATTTGTCCTGGCCAGCTGTGATATTTACCATATTTTGATGAATAGAGGCTT
TGTTATATCAATGTCTATTATTGGGGTGGCTGTTTTCTCTATAGGGATAGTTTTCTTGATAATCATTGATTATATAATAA
TGCAGGGTCAGGTAGTATATGAGAAGAAAAAATCCCGCTTTTTTTATGAAAAATCTATCAGGGATAGCATGACCGGGATT
TATAACCACCATTATATTGTTTCGACTTTGTCCAGGATGAAAGAACCTTTTTCCCTGGTTGTTCTTGATCTTGATAATTT
CAAGAATATAAATGACACTTATGGGCATCTGGCTGGTGATGAAGTCATTAAAAATGTTGCTATTAATTTACAAAACAGTA
TCCGCAAATATGATTATGTGGGAAGGTATGGCGGGGATGAATTTGTAATTATTTTAATGAACTGTTCTTTAGATGAACTT
AAAATGATGGCTAAAAAAATAAAAAGAGCTGTTGAAGAACCTGTGTATAAGTATAAGGGTAATAAAATCAGGGTGACTGC
CTCTATGGGCATATATAATGCAACAGAAAAAGAGGAAGGCGAACAGGTTATTTACCGGGCAGATCAGGCCCTGTATGCGG
CCAAAAAAAGTGGTAGGTCCGGTATAAAAATGTGGACAAAATCTGAATTTAGTGATGAGAGGGGGGAATAA

Upstream 100 bases:

>100_bases
CGGTAATTTCAGGAGAGATTTCAATAAAATAAAGGAACAGAGAATCAGGTGTTGAATTTATACAATATAAAAAGTTACTA
AGAAATGAGGTTGGTTGGTT

Downstream 100 bases:

>100_bases
CCCCCTTTTTTGGTTTCATATTTTTTTTTAATAGTATCCTTTAGTTATAATGGTTCTGATACAATTTTATAAGCTTATTC
TTAGTCTATTCCTTTAAAAA

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MKFKKGYLCTYLTIFVVVTGFMFLINIQTTRLLSNDKIYKIVNYSLDGSSDDLHYRLLEEGQRLFKFKTIIPESKLPATL
DGNYKIIIHRLAGQWYRVYINDVLIGSLGDIKKGYSNIWNAFGVYDLDQDLLQERNELVIEVYGLYEVGLLGYPVMITDN
VTANRLSNWFIILIRNIKLVAIGVLLTAFIILILLIKMSKKIKREYVYYALGAFTIIFMVLDYQVMYRLPVPPILFKKFI
ISGIYLASFFISIGLYKQFKVQLNLVLGLMVLGSAGYLIIFPGNMVDFKKSYSLLNLLISLNVLGWFYAGALNFKKSLYA
RVFSICSFVLFVLASCDIYHILMNRGFVISMSIIGVAVFSIGIVFLIIIDYIIMQGQVVYEKKKSRFFYEKSIRDSMTGI
YNHHYIVSTLSRMKEPFSLVVLDLDNFKNINDTYGHLAGDEVIKNVAINLQNSIRKYDYVGRYGGDEFVIILMNCSLDEL
KMMAKKIKRAVEEPVYKYKGNKIRVTASMGIYNATEKEEGEQVIYRADQALYAAKKSGRSGIKMWTKSEFSDERGE

Sequences:

>Translated_556_residues
MKFKKGYLCTYLTIFVVVTGFMFLINIQTTRLLSNDKIYKIVNYSLDGSSDDLHYRLLEEGQRLFKFKTIIPESKLPATL
DGNYKIIIHRLAGQWYRVYINDVLIGSLGDIKKGYSNIWNAFGVYDLDQDLLQERNELVIEVYGLYEVGLLGYPVMITDN
VTANRLSNWFIILIRNIKLVAIGVLLTAFIILILLIKMSKKIKREYVYYALGAFTIIFMVLDYQVMYRLPVPPILFKKFI
ISGIYLASFFISIGLYKQFKVQLNLVLGLMVLGSAGYLIIFPGNMVDFKKSYSLLNLLISLNVLGWFYAGALNFKKSLYA
RVFSICSFVLFVLASCDIYHILMNRGFVISMSIIGVAVFSIGIVFLIIIDYIIMQGQVVYEKKKSRFFYEKSIRDSMTGI
YNHHYIVSTLSRMKEPFSLVVLDLDNFKNINDTYGHLAGDEVIKNVAINLQNSIRKYDYVGRYGGDEFVIILMNCSLDEL
KMMAKKIKRAVEEPVYKYKGNKIRVTASMGIYNATEKEEGEQVIYRADQALYAAKKSGRSGIKMWTKSEFSDERGE
>Mature_556_residues
MKFKKGYLCTYLTIFVVVTGFMFLINIQTTRLLSNDKIYKIVNYSLDGSSDDLHYRLLEEGQRLFKFKTIIPESKLPATL
DGNYKIIIHRLAGQWYRVYINDVLIGSLGDIKKGYSNIWNAFGVYDLDQDLLQERNELVIEVYGLYEVGLLGYPVMITDN
VTANRLSNWFIILIRNIKLVAIGVLLTAFIILILLIKMSKKIKREYVYYALGAFTIIFMVLDYQVMYRLPVPPILFKKFI
ISGIYLASFFISIGLYKQFKVQLNLVLGLMVLGSAGYLIIFPGNMVDFKKSYSLLNLLISLNVLGWFYAGALNFKKSLYA
RVFSICSFVLFVLASCDIYHILMNRGFVISMSIIGVAVFSIGIVFLIIIDYIIMQGQVVYEKKKSRFFYEKSIRDSMTGI
YNHHYIVSTLSRMKEPFSLVVLDLDNFKNINDTYGHLAGDEVIKNVAINLQNSIRKYDYVGRYGGDEFVIILMNCSLDEL
KMMAKKIKRAVEEPVYKYKGNKIRVTASMGIYNATEKEEGEQVIYRADQALYAAKKSGRSGIKMWTKSEFSDERGE

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=35.1851851851852, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=36.875, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87082007, Length=164, Percent_Identity=35.3658536585366, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788381, Length=180, Percent_Identity=28.8888888888889, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787816, Length=155, Percent_Identity=34.8387096774194, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=32.5581395348837, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786584, Length=219, Percent_Identity=27.3972602739726, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787541, Length=187, Percent_Identity=28.3422459893048, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787056, Length=246, Percent_Identity=30.4878048780488, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787802, Length=155, Percent_Identity=28.3870967741935, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081974, Length=157, Percent_Identity=31.8471337579618, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788956, Length=211, Percent_Identity=27.9620853080569, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788085, Length=157, Percent_Identity=29.9363057324841, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081977, Length=181, Percent_Identity=27.6243093922652, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 63880; Mature: 63880

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKKGYLCTYLTIFVVVTGFMFLINIQTTRLLSNDKIYKIVNYSLDGSSDDLHYRLLEE
CCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHEECCCCEEEEEEEECCCCCCCHHHHHHHH
GQRLFKFKTIIPESKLPATLDGNYKIIIHRLAGQWYRVYINDVLIGSLGDIKKGYSNIWN
HHHHHHHHHHCCCCCCCEEECCCEEEEEEECCCCEEEEEEHHHHCCCCHHHHHHHHHHHH
AFGVYDLDQDLLQERNELVIEVYGLYEVGLLGYPVMITDNVTANRLSNWFIILIRNIKLV
HCCCCCCCHHHHHCCCCEEEEEECHHHHHHHCCCEEEECCCCHHHHCCEEEEEEECHHHH
AIGVLLTAFIILILLIKMSKKIKREYVYYALGAFTIIFMVLDYQVMYRLPVPPILFKKFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ISGIYLASFFISIGLYKQFKVQLNLVLGLMVLGSAGYLIIFPGNMVDFKKSYSLLNLLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
LNVLGWFYAGALNFKKSLYARVFSICSFVLFVLASCDIYHILMNRGFVISMSIIGVAVFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCEEEEHHHHHHHHHH
IGIVFLIIIDYIIMQGQVVYEKKKSRFFYEKSIRDSMTGIYNHHYIVSTLSRMKEPFSLV
HHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEE
VLDLDNFKNINDTYGHLAGDEVIKNVAINLQNSIRKYDYVGRYGGDEFVIILMNCSLDEL
EEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHH
KMMAKKIKRAVEEPVYKYKGNKIRVTASMGIYNATEKEEGEQVIYRADQALYAAKKSGRS
HHHHHHHHHHHHCCHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
GIKMWTKSEFSDERGE
CCEEEECCCCCCCCCC
>Mature Secondary Structure
MKFKKGYLCTYLTIFVVVTGFMFLINIQTTRLLSNDKIYKIVNYSLDGSSDDLHYRLLEE
CCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHEECCCCEEEEEEEECCCCCCCHHHHHHHH
GQRLFKFKTIIPESKLPATLDGNYKIIIHRLAGQWYRVYINDVLIGSLGDIKKGYSNIWN
HHHHHHHHHHCCCCCCCEEECCCEEEEEEECCCCEEEEEEHHHHCCCCHHHHHHHHHHHH
AFGVYDLDQDLLQERNELVIEVYGLYEVGLLGYPVMITDNVTANRLSNWFIILIRNIKLV
HCCCCCCCHHHHHCCCCEEEEEECHHHHHHHCCCEEEECCCCHHHHCCEEEEEEECHHHH
AIGVLLTAFIILILLIKMSKKIKREYVYYALGAFTIIFMVLDYQVMYRLPVPPILFKKFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ISGIYLASFFISIGLYKQFKVQLNLVLGLMVLGSAGYLIIFPGNMVDFKKSYSLLNLLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
LNVLGWFYAGALNFKKSLYARVFSICSFVLFVLASCDIYHILMNRGFVISMSIIGVAVFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCEEEEHHHHHHHHHH
IGIVFLIIIDYIIMQGQVVYEKKKSRFFYEKSIRDSMTGIYNHHYIVSTLSRMKEPFSLV
HHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEE
VLDLDNFKNINDTYGHLAGDEVIKNVAINLQNSIRKYDYVGRYGGDEFVIILMNCSLDEL
EEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHH
KMMAKKIKRAVEEPVYKYKGNKIRVTASMGIYNATEKEEGEQVIYRADQALYAAKKSGRS
HHHHHHHHHHHHCCHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
GIKMWTKSEFSDERGE
CCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]