| Definition | Halothermothrix orenii H 168 chromosome, complete genome. |
|---|---|
| Accession | NC_011899 |
| Length | 2,578,146 |
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The map label for this gene is hypF2 [H]
Identifier: 220931235
GI number: 220931235
Start: 399639
End: 401894
Strand: Direct
Name: hypF2 [H]
Synonym: Hore_03890
Alternate gene names: 220931235
Gene position: 399639-401894 (Clockwise)
Preceding gene: 220931234
Following gene: 220931236
Centisome position: 15.5
GC content: 39.89
Gene sequence:
>2256_bases ATGAAAAAGAGGCGGTTACAATTAGAAATAGAAGGTATTGTTCAGGGGGTGGGTTTCAGGCCTTTTATCTATCGTCTTGC CAGGGAAAATAATCTTAATGGGTGGGTTCTGAACACCAGTGGGGGTGTTTTAGTTGAAGTTGAAGGTAATCAAAAGACCC TTGAGATGTTTATCAGACAAATTGATGAGGAGTCACCCCCACTGGCCCAGATTACTACTATCAAATCTAGAGAAGTCTCT GTTAGAGAAGACAGTAGTTTTGTCATTAAGGATAGCAGGAAAACATATTATACGCAAGTACAGCTTCCTCCTGATATTGC CATTTGTAATGATTGTCTCCATGATATAATGGACCCTACCAACAGGCGCTATCGTTATCCCTTTACAAGTTGTGTTAACT GTGGTCCCCGTTTTAAGATTATCAAATCCCTCCCCTATGACCGCCCCCGGACTACAATGAAGAAATTTAAAATGTGTCCT GAATGTAATACTGAATACAATAATCCTCTGGATAGAAGGTTTCATGCCCAACCCAACGCTTGCCCACTATGTGGGCCCCA GCTCTGGCTAAAAAAAATGAGTGGGGAAAAGTGCCTTACCCGGGACCCCATAGGTCTTACCATTGACCTGCTTAAAAAGG GAAACATAATAGCCATTAAGGGCATTGGTGGATTTCACCTTATGTGTGATGCTACCGAAAGTGATGTGATAGCAAATCTC AGGACGAGGAAGAGGAGACCAGATAAACCCCTGGCGTTGATGATGAATAAACTGACTACTGTTAGAAAATATTGCAATGT TGGTAGTATGGAAGAGGAAATATTAACAGGGATAAGGCGTCCCATTGTCTTACTTGATAAAAAAGGGGAGAAGTTACCCC GTAATATTGCTCCTGGAATTAGATACTATGGTGTTATGTTGCCATATACCCCCCTGCATTATTTGTTGTTCGATAAAGGT ATAGAGGTTTTAATTGCTACCAGTGGAAACGTCAGTGGTAACCCCCTGGAATACCAAAATGGAGGTGTTTTTGAAAACTT AAAAGGTATTGCTGATTATGTTCTTGGGCATAACAGGGAGATATATGTTCCTGTAGATGATTCAGTCGTAAGGGTTGTTG GTGGTAAAAAGAGAGTGATAAGACGGGCCAGGGGTTACGTTCCCCAACCTCTCATGGTCGGGGGCCTTGACAATGGTCTG GCGTTGGGGGGTGACCAGAAAAATACCTTCTGTTTTGCCAGAAATAAGTATGCCTTTATAAGCCAGTATCTAGGGGATTT AGGGAATATCGATAACTATAATAATTTTAAATTAATGATAGATCATTTTAAGGAGTTATATAAAATAAAACCAGATTTTG TTGTCCATGACCTCCATCCGGATTATCAAACGACCTATTATGCTAGTTTTTACGGGGATAAGATAGGTGTCCAGCACCAT CATGCCCATATAGCCAGTTGTATGGCTGAAAATAACATAGACGAAAAAGTAATTGGTCTTGCTTTTGATGGAACAGGTCT GGGAAATGATGGTAATATATGGGGTGGTGAATTCTTAATTTGTGATTTTAAAGATTTTAAAAGGGGTGGCCATTTAAATT ATATGAAAATGCCCGGGGGTGATATGGCAATAAAGGAACCCTGGCGTCTGGCGGTTAGCTATCTTAATCGCTTAAGGTAT GATAAAGCTGATATTATAAACCTGTTGAGGATAGATGAAGTGGAGGCAGACATAATTCTGAAAATGCTCAATAAGGGTTT CAATTGTCCGGAAACATCAAGTATGGGTCGACTCTTTGATACTGTTGCCGCTTTAATAGGCTTGCGAAAAAGGATAACCT ATCAGGCTCAGGCAGCCCTTGAACTGGAATCAATTGCAGATAATAATACAGAAGAGATATATCATGTTAGTATCGAGGAA AAGGGTCAAAAATATGTTGTTAATACCGACCCGATGATGGGGGGTATTATCAGTGACCATAAAAAGGGTGTTAAAAGATC GATTATTTCATCTAAATTTCATAATACAGTTATTGCATTTACCCTGGAAATGTGCAGGCTAATCAGGCATAAATACGGTA TTAACAGTGTTGCTTTGAGTGGTGGAGTCTTTCAAAATAAATTATTATTAGAGATGTTATGTGCTGGATTGAAGGAACAA AATTTTAAAGTATATTCACAGGCAAAAATACCCTGCAATGATAGCGGGTTATCCCTGGGACAATTGGCTATAGCCAGTAA CCGGAGAAAGGATTAG
Upstream 100 bases:
>100_bases ACTTAAAGCAAATTAACAAAAATGCCCCGGTTTTTAAATTGTCAGGGAAGACAGGAGCAGGTCTGGATAAGCTATGTTTT TTTCTGGAGGAAAATCTTAC
Downstream 100 bases:
>100_bases TGACCAATGTGTATTGGTGTACCTGTAAAGATTATCAAAAAAAGAGAGTCACTGGCCCTGGCTGAACTGAATGGTGTAAA GAAAGAGATAAATATTGACC
Product: (NiFe) hydrogenase maturation protein HypF
Products: NA
Alternate protein names: Carbamoyl phosphate-converting enzyme hypF2; [NiFe]-hydrogenase maturation factor hypF2; Hydrogenase maturation protein hypF2 [H]
Number of amino acids: Translated: 751; Mature: 751
Protein sequence:
>751_residues MKKRRLQLEIEGIVQGVGFRPFIYRLARENNLNGWVLNTSGGVLVEVEGNQKTLEMFIRQIDEESPPLAQITTIKSREVS VREDSSFVIKDSRKTYYTQVQLPPDIAICNDCLHDIMDPTNRRYRYPFTSCVNCGPRFKIIKSLPYDRPRTTMKKFKMCP ECNTEYNNPLDRRFHAQPNACPLCGPQLWLKKMSGEKCLTRDPIGLTIDLLKKGNIIAIKGIGGFHLMCDATESDVIANL RTRKRRPDKPLALMMNKLTTVRKYCNVGSMEEEILTGIRRPIVLLDKKGEKLPRNIAPGIRYYGVMLPYTPLHYLLFDKG IEVLIATSGNVSGNPLEYQNGGVFENLKGIADYVLGHNREIYVPVDDSVVRVVGGKKRVIRRARGYVPQPLMVGGLDNGL ALGGDQKNTFCFARNKYAFISQYLGDLGNIDNYNNFKLMIDHFKELYKIKPDFVVHDLHPDYQTTYYASFYGDKIGVQHH HAHIASCMAENNIDEKVIGLAFDGTGLGNDGNIWGGEFLICDFKDFKRGGHLNYMKMPGGDMAIKEPWRLAVSYLNRLRY DKADIINLLRIDEVEADIILKMLNKGFNCPETSSMGRLFDTVAALIGLRKRITYQAQAALELESIADNNTEEIYHVSIEE KGQKYVVNTDPMMGGIISDHKKGVKRSIISSKFHNTVIAFTLEMCRLIRHKYGINSVALSGGVFQNKLLLEMLCAGLKEQ NFKVYSQAKIPCNDSGLSLGQLAIASNRRKD
Sequences:
>Translated_751_residues MKKRRLQLEIEGIVQGVGFRPFIYRLARENNLNGWVLNTSGGVLVEVEGNQKTLEMFIRQIDEESPPLAQITTIKSREVS VREDSSFVIKDSRKTYYTQVQLPPDIAICNDCLHDIMDPTNRRYRYPFTSCVNCGPRFKIIKSLPYDRPRTTMKKFKMCP ECNTEYNNPLDRRFHAQPNACPLCGPQLWLKKMSGEKCLTRDPIGLTIDLLKKGNIIAIKGIGGFHLMCDATESDVIANL RTRKRRPDKPLALMMNKLTTVRKYCNVGSMEEEILTGIRRPIVLLDKKGEKLPRNIAPGIRYYGVMLPYTPLHYLLFDKG IEVLIATSGNVSGNPLEYQNGGVFENLKGIADYVLGHNREIYVPVDDSVVRVVGGKKRVIRRARGYVPQPLMVGGLDNGL ALGGDQKNTFCFARNKYAFISQYLGDLGNIDNYNNFKLMIDHFKELYKIKPDFVVHDLHPDYQTTYYASFYGDKIGVQHH HAHIASCMAENNIDEKVIGLAFDGTGLGNDGNIWGGEFLICDFKDFKRGGHLNYMKMPGGDMAIKEPWRLAVSYLNRLRY DKADIINLLRIDEVEADIILKMLNKGFNCPETSSMGRLFDTVAALIGLRKRITYQAQAALELESIADNNTEEIYHVSIEE KGQKYVVNTDPMMGGIISDHKKGVKRSIISSKFHNTVIAFTLEMCRLIRHKYGINSVALSGGVFQNKLLLEMLCAGLKEQ NFKVYSQAKIPCNDSGLSLGQLAIASNRRKD >Mature_751_residues MKKRRLQLEIEGIVQGVGFRPFIYRLARENNLNGWVLNTSGGVLVEVEGNQKTLEMFIRQIDEESPPLAQITTIKSREVS VREDSSFVIKDSRKTYYTQVQLPPDIAICNDCLHDIMDPTNRRYRYPFTSCVNCGPRFKIIKSLPYDRPRTTMKKFKMCP ECNTEYNNPLDRRFHAQPNACPLCGPQLWLKKMSGEKCLTRDPIGLTIDLLKKGNIIAIKGIGGFHLMCDATESDVIANL RTRKRRPDKPLALMMNKLTTVRKYCNVGSMEEEILTGIRRPIVLLDKKGEKLPRNIAPGIRYYGVMLPYTPLHYLLFDKG IEVLIATSGNVSGNPLEYQNGGVFENLKGIADYVLGHNREIYVPVDDSVVRVVGGKKRVIRRARGYVPQPLMVGGLDNGL ALGGDQKNTFCFARNKYAFISQYLGDLGNIDNYNNFKLMIDHFKELYKIKPDFVVHDLHPDYQTTYYASFYGDKIGVQHH HAHIASCMAENNIDEKVIGLAFDGTGLGNDGNIWGGEFLICDFKDFKRGGHLNYMKMPGGDMAIKEPWRLAVSYLNRLRY DKADIINLLRIDEVEADIILKMLNKGFNCPETSSMGRLFDTVAALIGLRKRITYQAQAALELESIADNNTEEIYHVSIEE KGQKYVVNTDPMMGGIISDHKKGVKRSIISSKFHNTVIAFTLEMCRLIRHKYGINSVALSGGVFQNKLLLEMLCAGLKEQ NFKVYSQAKIPCNDSGLSLGQLAIASNRRKD
Specific function: Along with hypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carb
COG id: COG0068
COG function: function code O; Hydrogenase maturation factor
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 YrdC-like domain [H]
Homologues:
Organism=Escherichia coli, GI2367152, Length=755, Percent_Identity=38.2781456953642, Blast_Score=443, Evalue=1e-125,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001792 - InterPro: IPR017968 - InterPro: IPR004421 - InterPro: IPR017945 - InterPro: IPR006070 - InterPro: IPR011125 [H]
Pfam domain/function: PF00708 Acylphosphatase; PF01300 Sua5_yciO_yrdC; PF07503 zf-HYPF [H]
EC number: NA
Molecular weight: Translated: 84945; Mature: 84945
Theoretical pI: Translated: 9.15; Mature: 9.15
Prosite motif: PS00150 ACYLPHOSPHATASE_1 ; PS51160 ACYLPHOSPHATASE_3 ; PS51163 YRDC
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.4 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 5.5 %Cys+Met (Translated Protein) 2.4 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 5.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKRRLQLEIEGIVQGVGFRPFIYRLARENNLNGWVLNTSGGVLVEVEGNQKTLEMFIRQ CCCCEEEEEEEHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEECCCHHHHHHHHHH IDEESPPLAQITTIKSREVSVREDSSFVIKDSRKTYYTQVQLPPDIAICNDCLHDIMDPT HCCCCCCCEEEEEECCCCEEEECCCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCCC NRRYRYPFTSCVNCGPRFKIIKSLPYDRPRTTMKKFKMCPECNTEYNNPLDRRFHAQPNA CCEEECCCHHHHCCCCCHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCC CPLCGPQLWLKKMSGEKCLTRDPIGLTIDLLKKGNIIAIKGIGGFHLMCDATESDVIANL CCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCEEEEECCCCHHHHHHH RTRKRRPDKPLALMMNKLTTVRKYCNVGSMEEEILTGIRRPIVLLDKKGEKLPRNIAPGI HHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC RYYGVMLPYTPLHYLLFDKGIEVLIATSGNVSGNPLEYQNGGVFENLKGIADYVLGHNRE EEEEEECCCCHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCE IYVPVDDSVVRVVGGKKRVIRRARGYVPQPLMVGGLDNGLALGGDQKNTFCFARNKYAFI EEEECCCCEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCEECCCCCCEEEEECCCHHHH SQYLGDLGNIDNYNNFKLMIDHFKELYKIKPDFVVHDLHPDYQTTYYASFYGDKIGVQHH HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCHH HAHIASCMAENNIDEKVIGLAFDGTGLGNDGNIWGGEFLICDFKDFKRGGHLNYMKMPGG HHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECHHHCCCCCEEEEECCCC DMAIKEPWRLAVSYLNRLRYDKADIINLLRIDEVEADIILKMLNKGFNCPETSSMGRLFD CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH TVAALIGLRKRITYQAQAALELESIADNNTEEIYHVSIEEKGQKYVVNTDPMMGGIISDH HHHHHHHHHHHHHHHHHHHEEHHHHCCCCCCEEEEEEEECCCCEEEEECCCCCCCHHHHH KKGVKRSIISSKFHNTVIAFTLEMCRLIRHKYGINSVALSGGVFQNKLLLEMLCAGLKEQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHCCCCCC NFKVYSQAKIPCNDSGLSLGQLAIASNRRKD CEEEEEEEECCCCCCCCCHHHEEECCCCCCC >Mature Secondary Structure MKKRRLQLEIEGIVQGVGFRPFIYRLARENNLNGWVLNTSGGVLVEVEGNQKTLEMFIRQ CCCCEEEEEEEHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEECCCHHHHHHHHHH IDEESPPLAQITTIKSREVSVREDSSFVIKDSRKTYYTQVQLPPDIAICNDCLHDIMDPT HCCCCCCCEEEEEECCCCEEEECCCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCCC NRRYRYPFTSCVNCGPRFKIIKSLPYDRPRTTMKKFKMCPECNTEYNNPLDRRFHAQPNA CCEEECCCHHHHCCCCCHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCC CPLCGPQLWLKKMSGEKCLTRDPIGLTIDLLKKGNIIAIKGIGGFHLMCDATESDVIANL CCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCEEEEECCCCHHHHHHH RTRKRRPDKPLALMMNKLTTVRKYCNVGSMEEEILTGIRRPIVLLDKKGEKLPRNIAPGI HHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC RYYGVMLPYTPLHYLLFDKGIEVLIATSGNVSGNPLEYQNGGVFENLKGIADYVLGHNRE EEEEEECCCCHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCE IYVPVDDSVVRVVGGKKRVIRRARGYVPQPLMVGGLDNGLALGGDQKNTFCFARNKYAFI EEEECCCCEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCEECCCCCCEEEEECCCHHHH SQYLGDLGNIDNYNNFKLMIDHFKELYKIKPDFVVHDLHPDYQTTYYASFYGDKIGVQHH HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCHH HAHIASCMAENNIDEKVIGLAFDGTGLGNDGNIWGGEFLICDFKDFKRGGHLNYMKMPGG HHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECHHHCCCCCEEEEECCCC DMAIKEPWRLAVSYLNRLRYDKADIINLLRIDEVEADIILKMLNKGFNCPETSSMGRLFD CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH TVAALIGLRKRITYQAQAALELESIADNNTEEIYHVSIEEKGQKYVVNTDPMMGGIISDH HHHHHHHHHHHHHHHHHHHEEHHHHCCCCCCEEEEEEEECCCCEEEEECCCCCCCHHHHH KKGVKRSIISSKFHNTVIAFTLEMCRLIRHKYGINSVALSGGVFQNKLLLEMLCAGLKEQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHCCCCCC NFKVYSQAKIPCNDSGLSLGQLAIASNRRKD CEEEEEEEECCCCCCCCCHHHEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9799289; 12948488 [H]