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The map label for this gene is cycZ [H]

Identifier: 220931226

GI number: 220931226

Start: 391924

End: 392601

Strand: Direct

Name: cycZ [H]

Synonym: Hore_03790

Alternate gene names: 220931226

Gene position: 391924-392601 (Clockwise)

Preceding gene: 220931225

Following gene: 220931227

Centisome position: 15.2

GC content: 39.38

Gene sequence:

>678_bases
ATGAAGGATAAGGTTAATTCTATACTTCTGATTATACTTATTTTCACAATGTTAACCAACCTGTATCTTATATTTTACTA
TGCCCCCCTGGAAAAGGTGATGGGGGTGGTTCAGAAGATATTTTATTTTCATGTTGCGTCTGCCTGGATTGGTTTTCTGG
CTCTGGCAGTTGTTTTTGCATCTAATATTCTCTACCTCAGATGTGGCCGGAAAAAGTGGAGTCAGTTGTCACTGGCTTCT
GCCGAGATAGGGGTTGTTTTTATAAGTATAGTCCTGATTACCGGTCCTTTATGGGCAAAGCCTGTCTGGAATACCTGGTG
GACCTGGGATCCCAGGTTAACGACAACTCTTATTCTATGGTTTATGTATGTAGCCTATCTTATCTTACATGGTGGCCGGG
AAAAGAATGAAAAGAGAGAACGACTGGCAGCTGTTTACGGGATTATAGCCTTTATCAATGTCCCCCTGGTTTTTTTCTCT
ATAAGATGGTGGCGGACTATCCACCCGGTAGTTATTTCAACATCAGGTATAAGTATAACCGGAGAAATGTTATTTACCCT
TCTTTTCAGTCTTGCTACCTTTACGTTATTATATGTTTATTTGCTCAAAACAAGGTGCAGGGGAATTAAGCTGGCTTATA
AAATTGATTTATTAAAAGAAAGAATAGGAGGGTATTAA

Upstream 100 bases:

>100_bases
TACGGTGGGTTAATTTTCTGATTCTCTTTGATTTAATACATTTTTTGATACCATTATTTATCTTTGATTATATCATGGAA
AACTAAATGGGGGTAAAGCC

Downstream 100 bases:

>100_bases
CTTGTCTTACTTAGTAATTGCCTATGGATTTATCTGGCTATTGATTCTGGGTTACATATTCTTTATAAACAGACAGCAGA
TTCGACTGGAACGGGAGTTA

Product: cytochrome c assembly protein

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKDKVNSILLIILIFTMLTNLYLIFYYAPLEKVMGVVQKIFYFHVASAWIGFLALAVVFASNILYLRCGRKKWSQLSLAS
AEIGVVFISIVLITGPLWAKPVWNTWWTWDPRLTTTLILWFMYVAYLILHGGREKNEKRERLAAVYGIIAFINVPLVFFS
IRWWRTIHPVVISTSGISITGEMLFTLLFSLATFTLLYVYLLKTRCRGIKLAYKIDLLKERIGGY

Sequences:

>Translated_225_residues
MKDKVNSILLIILIFTMLTNLYLIFYYAPLEKVMGVVQKIFYFHVASAWIGFLALAVVFASNILYLRCGRKKWSQLSLAS
AEIGVVFISIVLITGPLWAKPVWNTWWTWDPRLTTTLILWFMYVAYLILHGGREKNEKRERLAAVYGIIAFINVPLVFFS
IRWWRTIHPVVISTSGISITGEMLFTLLFSLATFTLLYVYLLKTRCRGIKLAYKIDLLKERIGGY
>Mature_225_residues
MKDKVNSILLIILIFTMLTNLYLIFYYAPLEKVMGVVQKIFYFHVASAWIGFLALAVVFASNILYLRCGRKKWSQLSLAS
AEIGVVFISIVLITGPLWAKPVWNTWWTWDPRLTTTLILWFMYVAYLILHGGREKNEKRERLAAVYGIIAFINVPLVFFS
IRWWRTIHPVVISTSGISITGEMLFTLLFSLATFTLLYVYLLKTRCRGIKLAYKIDLLKERIGGY

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=188, Percent_Identity=33.5106382978723, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 26047; Mature: 26047

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKVNSILLIILIFTMLTNLYLIFYYAPLEKVMGVVQKIFYFHVASAWIGFLALAVVFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNILYLRCGRKKWSQLSLASAEIGVVFISIVLITGPLWAKPVWNTWWTWDPRLTTTLILW
CCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
FMYVAYLILHGGREKNEKRERLAAVYGIIAFINVPLVFFSIRWWRTIHPVVISTSGISIT
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
GEMLFTLLFSLATFTLLYVYLLKTRCRGIKLAYKIDLLKERIGGY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKDKVNSILLIILIFTMLTNLYLIFYYAPLEKVMGVVQKIFYFHVASAWIGFLALAVVFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNILYLRCGRKKWSQLSLASAEIGVVFISIVLITGPLWAKPVWNTWWTWDPRLTTTLILW
CCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
FMYVAYLILHGGREKNEKRERLAAVYGIIAFINVPLVFFSIRWWRTIHPVVISTSGISIT
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
GEMLFTLLFSLATFTLLYVYLLKTRCRGIKLAYKIDLLKERIGGY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]