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The map label for this gene is clpP [H]

Identifier: 220931198

GI number: 220931198

Start: 364810

End: 365514

Strand: Direct

Name: clpP [H]

Synonym: Hore_03500

Alternate gene names: 220931198

Gene position: 364810-365514 (Clockwise)

Preceding gene: 220931197

Following gene: 220931199

Centisome position: 14.15

GC content: 33.62

Gene sequence:

>705_bases
ATGAGTAAAAATACCCTTTTTAAAGTCTTTAATGAGAGTGATAATAACGCTGCAGAGATTTATTTGCATGGCCCGATCAG
AAACCCTCTTCCAGATGAAGACGAAGAAGATGTTATAACCTTGAAAGAAGTAAGGAATAAGTTAAATAAAATAACTGCCG
ACAAAATAATAGTACACCTAAACAGTACAGGCGGGGATTTATTTCAGTCAGTTGCTATTCATAACCTGTTTAAGGATCAT
AAGGCAGAAATAATAATGATAAATGATGGTATAGCAGCAAGTGGAGGAAGTATTATCTTAATGGCCGGGGACAAGATTAA
ATTCTACCCAAACAGTATAATGATGATCCACGCTGCCCACACAATAACTTATGGTGATGCAAAATATCACAGAGAAGTTG
CCAGGAAATTAGATAAGATAGATAAGTCTCTAAAGGAAAATTATTCTCAAAGATTTACTGGGGCTGAAAAAGAATTAGAA
AAGCTTATCCAGGAAGAAACCTGGCTTACAGCTAAAGAGGCCAAAGAAAAAGGGTTTTGTGATGAAATAATAAGTGATAA
CACAGAAGAAAGCAGGGCAGAAAATAAGAGTAATAATCTATTTATGAATATGAAGACAAATAGCAATATTAAGGGTAAAC
TAATGAAGAAATATGGTAGTAGAAATAATAAATCATTACTCAATAAGCTAGGAGGCAATAAGTAA

Upstream 100 bases:

>100_bases
AATAGGAGTTGGCAATATGATAACGATAAGGGAAAGAGCAGGCCCAAATAATAAATAAACCATAAACTACTCAAAAATAA
AATATTAAGGAGTTGAAACA

Downstream 100 bases:

>100_bases
TGTTTAACAAACTTAATAAAGTTATTAAGAAAAAAAGAGAAACCAGAAGGGGGTTAGTAACAAAATGACTGAACTTAAAC
TGCTGGAAAACCGAAAAGAA

Product: peptidase S14 ClpP

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSKNTLFKVFNESDNNAAEIYLHGPIRNPLPDEDEEDVITLKEVRNKLNKITADKIIVHLNSTGGDLFQSVAIHNLFKDH
KAEIIMINDGIAASGGSIILMAGDKIKFYPNSIMMIHAAHTITYGDAKYHREVARKLDKIDKSLKENYSQRFTGAEKELE
KLIQEETWLTAKEAKEKGFCDEIISDNTEESRAENKSNNLFMNMKTNSNIKGKLMKKYGSRNNKSLLNKLGGNK

Sequences:

>Translated_234_residues
MSKNTLFKVFNESDNNAAEIYLHGPIRNPLPDEDEEDVITLKEVRNKLNKITADKIIVHLNSTGGDLFQSVAIHNLFKDH
KAEIIMINDGIAASGGSIILMAGDKIKFYPNSIMMIHAAHTITYGDAKYHREVARKLDKIDKSLKENYSQRFTGAEKELE
KLIQEETWLTAKEAKEKGFCDEIISDNTEESRAENKSNNLFMNMKTNSNIKGKLMKKYGSRNNKSLLNKLGGNK
>Mature_233_residues
SKNTLFKVFNESDNNAAEIYLHGPIRNPLPDEDEEDVITLKEVRNKLNKITADKIIVHLNSTGGDLFQSVAIHNLFKDHK
AEIIMINDGIAASGGSIILMAGDKIKFYPNSIMMIHAAHTITYGDAKYHREVARKLDKIDKSLKENYSQRFTGAEKELEK
LIQEETWLTAKEAKEKGFCDEIISDNTEESRAENKSNNLFMNMKTNSNIKGKLMKKYGSRNNKSLLNKLGGNK

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 26463; Mature: 26332

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNTLFKVFNESDNNAAEIYLHGPIRNPLPDEDEEDVITLKEVRNKLNKITADKIIVHL
CCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCEEEEEE
NSTGGDLFQSVAIHNLFKDHKAEIIMINDGIAASGGSIILMAGDKIKFYPNSIMMIHAAH
ECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCEEEECCCCEEEEEEEE
TITYGDAKYHREVARKLDKIDKSLKENYSQRFTGAEKELEKLIQEETWLTAKEAKEKGFC
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCH
DEIISDNTEESRAENKSNNLFMNMKTNSNIKGKLMKKYGSRNNKSLLNKLGGNK
HHHHCCCCHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
SKNTLFKVFNESDNNAAEIYLHGPIRNPLPDEDEEDVITLKEVRNKLNKITADKIIVHL
CCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCEEEEEE
NSTGGDLFQSVAIHNLFKDHKAEIIMINDGIAASGGSIILMAGDKIKFYPNSIMMIHAAH
ECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCEEEECCCCEEEEEEEE
TITYGDAKYHREVARKLDKIDKSLKENYSQRFTGAEKELEKLIQEETWLTAKEAKEKGFC
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCH
DEIISDNTEESRAENKSNNLFMNMKTNSNIKGKLMKKYGSRNNKSLLNKLGGNK
HHHHCCCCHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA