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The map label for this gene is accD

Identifier: 220931167

GI number: 220931167

Start: 327425

End: 328303

Strand: Direct

Name: accD

Synonym: Hore_03190

Alternate gene names: 220931167

Gene position: 327425-328303 (Clockwise)

Preceding gene: 220931166

Following gene: 220931168

Centisome position: 12.7

GC content: 41.87

Gene sequence:

>879_bases
ATGTTAAAAGACCTGTTCGGAAAGTCCAGGTATGTTACGGTTAAAAGAGAAGAACATACCAGTTCAAAGAAAAAAGCCCC
GGGTGATGATAGACTATGGACCAAGTGTAAAAAATGTAAAGAAATTATATTTAATAAAAAGCTGGTAGAAAACTTAATGG
TCTGTCCCAAATGTGGTTATCACTTCAGGCTCACAGCAAGGGACAGGTTAGCGATTACCATTGATGAAGGTAGTTTTAAA
GAATTTGGTCAGGATATTAAAACAGTGGACCCTCTGGAGTTTCCAGGTTATCAGCAAAAAATAGGAAAATATAAAGTAAA
AACCGGTATGGAAGAGGCCATAATAACAGGAGAAGCTACTATTGAAGGATATCCTGTTGTTATTGCCGTTATGGACTTTC
ACTTCATGGGTGGAAGTATGGGTTCTGTAGTCGGTGAAAAGGTGACCAGGGCTATTGAAAAGGCGATTTCTACCAGAAAA
CCACTGGTCATATTTAGTACTGCCGGAGGAGCCCGGATGCAGGAAGGTATGCTGTCATTAATGCAGATGGCCAAGACCAG
TGCCGCCATTAAAAGGCTTAATAAAGCAGGTATTTTATATGTTTCAGTTATGACCGATCCTACTTCTGGTGGGGTGACGG
CCAGTTTTGCCTCTCTTGGTGATATCATTATAGCCGAGAAGGGGGCTTTAATAGCATTTGCCGGGCCCAGGGTCATTAAG
CAGACTATCAGTACCAAACTCCCGGAAGGGTTTCAGCGAGCTGAATTTTTACTTGACCATGGTATGGTTGATATGGTTCT
TTCCAGGCATGAGATTAGAGATGAACTTGCTAAAATCCTTAAGATACACCAGATTGGGGTGGTGAGTAATGGCGGGTAA

Upstream 100 bases:

>100_bases
GATGTTCATCAGTTCCTGAATGATGCTCTGTAGTAAAAACGTTTCTGGTTTAGGGAAAGATATTAATTAAAAAAACCAGA
AATATAACGAGGTGAGTTAC

Downstream 100 bases:

>100_bases
TAATATCCTTGATTTTGAAAAACCCTTGCTCGAACTTAAAGATAAGATTGAAGAGTTACAGTCCTTTATGGATGAAAAAG
GTATAGACCTTAGTGAAGAA

Product: acetyl-CoA carboxylase, carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MLKDLFGKSRYVTVKREEHTSSKKKAPGDDRLWTKCKKCKEIIFNKKLVENLMVCPKCGYHFRLTARDRLAITIDEGSFK
EFGQDIKTVDPLEFPGYQQKIGKYKVKTGMEEAIITGEATIEGYPVVIAVMDFHFMGGSMGSVVGEKVTRAIEKAISTRK
PLVIFSTAGGARMQEGMLSLMQMAKTSAAIKRLNKAGILYVSVMTDPTSGGVTASFASLGDIIIAEKGALIAFAGPRVIK
QTISTKLPEGFQRAEFLLDHGMVDMVLSRHEIRDELAKILKIHQIGVVSNGG

Sequences:

>Translated_292_residues
MLKDLFGKSRYVTVKREEHTSSKKKAPGDDRLWTKCKKCKEIIFNKKLVENLMVCPKCGYHFRLTARDRLAITIDEGSFK
EFGQDIKTVDPLEFPGYQQKIGKYKVKTGMEEAIITGEATIEGYPVVIAVMDFHFMGGSMGSVVGEKVTRAIEKAISTRK
PLVIFSTAGGARMQEGMLSLMQMAKTSAAIKRLNKAGILYVSVMTDPTSGGVTASFASLGDIIIAEKGALIAFAGPRVIK
QTISTKLPEGFQRAEFLLDHGMVDMVLSRHEIRDELAKILKIHQIGVVSNGG
>Mature_292_residues
MLKDLFGKSRYVTVKREEHTSSKKKAPGDDRLWTKCKKCKEIIFNKKLVENLMVCPKCGYHFRLTARDRLAITIDEGSFK
EFGQDIKTVDPLEFPGYQQKIGKYKVKTGMEEAIITGEATIEGYPVVIAVMDFHFMGGSMGSVVGEKVTRAIEKAISTRK
PLVIFSTAGGARMQEGMLSLMQMAKTSAAIKRLNKAGILYVSVMTDPTSGGVTASFASLGDIIIAEKGALIAFAGPRVIK
QTISTKLPEGFQRAEFLLDHGMVDMVLSRHEIRDELAKILKIHQIGVVSNGG

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Homo sapiens, GI119943100, Length=191, Percent_Identity=25.6544502617801, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI295821216, Length=198, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788655, Length=265, Percent_Identity=49.811320754717, Blast_Score=280, Evalue=8e-77,
Organism=Caenorhabditis elegans, GI25147362, Length=188, Percent_Identity=25.531914893617, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25147359, Length=188, Percent_Identity=25.531914893617, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_HALOH (B8D1K3)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508075.1
- GeneID:   7314705
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_03190
- HOGENOM:   HBG285696
- OMA:   AGEAFIT
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 32123; Mature: 32123

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKDLFGKSRYVTVKREEHTSSKKKAPGDDRLWTKCKKCKEIIFNKKLVENLMVCPKCGY
CCHHHCCCCEEEEEECHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HFRLTARDRLAITIDEGSFKEFGQDIKTVDPLEFPGYQQKIGKYKVKTGMEEAIITGEAT
EEEEEECCEEEEEECCCCHHHHCCCCCCCCCCCCCCHHHHHCCCHHHCCCHHHEEECCCE
IEGYPVVIAVMDFHFMGGSMGSVVGEKVTRAIEKAISTRKPLVIFSTAGGARMQEGMLSL
ECCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
MQMAKTSAAIKRLNKAGILYVSVMTDPTSGGVTASFASLGDIIIAEKGALIAFAGPRVIK
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEHHHHHCCEEEECCCCEEEECCHHHHH
QTISTKLPEGFQRAEFLLDHGMVDMVLSRHEIRDELAKILKIHQIGVVSNGG
HHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
>Mature Secondary Structure
MLKDLFGKSRYVTVKREEHTSSKKKAPGDDRLWTKCKKCKEIIFNKKLVENLMVCPKCGY
CCHHHCCCCEEEEEECHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HFRLTARDRLAITIDEGSFKEFGQDIKTVDPLEFPGYQQKIGKYKVKTGMEEAIITGEAT
EEEEEECCEEEEEECCCCHHHHCCCCCCCCCCCCCCHHHHHCCCHHHCCCHHHEEECCCE
IEGYPVVIAVMDFHFMGGSMGSVVGEKVTRAIEKAISTRKPLVIFSTAGGARMQEGMLSL
ECCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
MQMAKTSAAIKRLNKAGILYVSVMTDPTSGGVTASFASLGDIIIAEKGALIAFAGPRVIK
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEHHHHHCCEEEECCCCEEEECCHHHHH
QTISTKLPEGFQRAEFLLDHGMVDMVLSRHEIRDELAKILKIHQIGVVSNGG
HHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA