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The map label for this gene is argC

Identifier: 220931130

GI number: 220931130

Start: 284878

End: 285921

Strand: Direct

Name: argC

Synonym: Hore_02820

Alternate gene names: 220931130

Gene position: 284878-285921 (Clockwise)

Preceding gene: 220931129

Following gene: 220931131

Centisome position: 11.05

GC content: 37.74

Gene sequence:

>1044_bases
ATGATCAGGGTAAGTATTATTGGAGCTACCGGATATACCGGTATTGAATTAGTCAGGCTCCTTGCTAACCATCCTGAAGT
AGAATTATCATCACTGGTCAGCAGGAATGCCAGTAATAAACCTTTATCTGATATATATCCTCAGTTTATAGGTAGAATAG
ACCTTAAGTTTTCTGAATATGACTGTCAAGCTATCTGTCAAAATTCTGATATAGTTTTTACTGCCCTACCCCATGGTATT
TCTCAGGAAATTGTAGGTGAATTATATAACTGCGGGGTTAAAATAATTGATCTGAGTGGTGATTTCAGGTATAAAGATTC
AGCTATCTATGAAAAGTGGTATCGGGAAAACCATCATTACCCTCATTTACTGGAAAAGGCGGTTTATGGACTGGTAGAAA
TAAATAGAAATAGTATTAAGAGGTCTTCTCTGGTTGCAAATCCCGGTTGTTATCCTACGGCTTCATTGCTGGGTTTATGG
CCTGTAATTAGTGAAAATTTAATTAACTTAAATACAATAATTATTGATGCCAAATCCGGGGTCTCCGGGGCTGGAAAAGG
TTTAAAGAGAGGAAGTCATTTTGTAGAGGTAGATGAAAATATAAAGGGATATAGTATTGGTAGTCACCGCCATACTTCTG
AAATTGAAGAGATTATTAAAACCTTTTCCGGAAATCAAAAGGCTATTGTTTCTTTTACCCCACACCTGGTTCCAATGAAA
CGGGGCATTCTGGCTACTATTTATGTCAAGTTGAAGCAGAGCATATCGGAAAGGGCCCTGAGGGAATTATACCATAAGTA
CTATCCGGATCATGGTTTTATTAAGGTTTTACCCCGTGACATTTTTCCTGAAACTAAATATGTGGTGGGAACAAATTACT
GTTATATTGGCCTTAAATATGATACCAGGACTGAACGGCTGGTGATTATTTCTGCTATTGATAATCTGGTTAAAGGAGCA
GCCGGTCAGGCTATCCAGAATATGAATGTTATGTTTAATTTACCGGAGTACATGGGATTAAAGCAGGTAGGGGTATTTCC
TTGA

Upstream 100 bases:

>100_bases
CGGGTATTTTTAAAAACACCCCATACGGGGGGTTTTTTTAAAACTTTTTCTTGAATACTTATACTTTCGCATGTATAATA
TTACGAAAAGGGGTGAGAAA

Downstream 100 bases:

>100_bases
TTTAGTTTAGTATTTAAATACAAGTCTATACATCCTTTTTTATATTTAAAGGAGAGAGGAGAGGAGAAGGTGTCAGAACT
TGAATTAATAACAGGTGGTA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MIRVSIIGATGYTGIELVRLLANHPEVELSSLVSRNASNKPLSDIYPQFIGRIDLKFSEYDCQAICQNSDIVFTALPHGI
SQEIVGELYNCGVKIIDLSGDFRYKDSAIYEKWYRENHHYPHLLEKAVYGLVEINRNSIKRSSLVANPGCYPTASLLGLW
PVISENLINLNTIIIDAKSGVSGAGKGLKRGSHFVEVDENIKGYSIGSHRHTSEIEEIIKTFSGNQKAIVSFTPHLVPMK
RGILATIYVKLKQSISERALRELYHKYYPDHGFIKVLPRDIFPETKYVVGTNYCYIGLKYDTRTERLVIISAIDNLVKGA
AGQAIQNMNVMFNLPEYMGLKQVGVFP

Sequences:

>Translated_347_residues
MIRVSIIGATGYTGIELVRLLANHPEVELSSLVSRNASNKPLSDIYPQFIGRIDLKFSEYDCQAICQNSDIVFTALPHGI
SQEIVGELYNCGVKIIDLSGDFRYKDSAIYEKWYRENHHYPHLLEKAVYGLVEINRNSIKRSSLVANPGCYPTASLLGLW
PVISENLINLNTIIIDAKSGVSGAGKGLKRGSHFVEVDENIKGYSIGSHRHTSEIEEIIKTFSGNQKAIVSFTPHLVPMK
RGILATIYVKLKQSISERALRELYHKYYPDHGFIKVLPRDIFPETKYVVGTNYCYIGLKYDTRTERLVIISAIDNLVKGA
AGQAIQNMNVMFNLPEYMGLKQVGVFP
>Mature_347_residues
MIRVSIIGATGYTGIELVRLLANHPEVELSSLVSRNASNKPLSDIYPQFIGRIDLKFSEYDCQAICQNSDIVFTALPHGI
SQEIVGELYNCGVKIIDLSGDFRYKDSAIYEKWYRENHHYPHLLEKAVYGLVEINRNSIKRSSLVANPGCYPTASLLGLW
PVISENLINLNTIIIDAKSGVSGAGKGLKRGSHFVEVDENIKGYSIGSHRHTSEIEEIIKTFSGNQKAIVSFTPHLVPMK
RGILATIYVKLKQSISERALRELYHKYYPDHGFIKVLPRDIFPETKYVVGTNYCYIGLKYDTRTERLVIISAIDNLVKGA
AGQAIQNMNVMFNLPEYMGLKQVGVFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=345, Percent_Identity=37.6811594202899, Blast_Score=224, Evalue=9e-60,
Organism=Saccharomyces cerevisiae, GI6320913, Length=345, Percent_Identity=31.5942028985507, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_HALOH (B8D1G6)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508038.1
- ProteinModelPortal:   B8D1G6
- SMR:   B8D1G6
- GeneID:   7314668
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_02820
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38916; Mature: 38916

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 150-150

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVSIIGATGYTGIELVRLLANHPEVELSSLVSRNASNKPLSDIYPQFIGRIDLKFSEY
CEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHCEEEEEECCC
DCQAICQNSDIVFTALPHGISQEIVGELYNCGVKIIDLSGDFRYKDSAIYEKWYRENHHY
CHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCCCC
PHLLEKAVYGLVEINRNSIKRSSLVANPGCYPTASLLGLWPVISENLINLNTIIIDAKSG
HHHHHHHHHHHHEECCHHHHHHHEECCCCCCCHHHHHHHHHHHHCCEEEEEEEEEECCCC
VSGAGKGLKRGSHFVEVDENIKGYSIGSHRHTSEIEEIIKTFSGNQKAIVSFTPHLVPMK
CCCCCCHHHCCCCEEEECCCCCCEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHH
RGILATIYVKLKQSISERALRELYHKYYPDHGFIKVLPRDIFPETKYVVGTNYCYIGLKY
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHCCCCCCEEEECCEEEEEEEE
DTRTERLVIISAIDNLVKGAAGQAIQNMNVMFNLPEYMGLKQVGVFP
CCCCCEEEEEHHHHHHHHCHHHHHHHCCCEEEECHHHCCCCCCCCCC
>Mature Secondary Structure
MIRVSIIGATGYTGIELVRLLANHPEVELSSLVSRNASNKPLSDIYPQFIGRIDLKFSEY
CEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHCEEEEEECCC
DCQAICQNSDIVFTALPHGISQEIVGELYNCGVKIIDLSGDFRYKDSAIYEKWYRENHHY
CHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCCCC
PHLLEKAVYGLVEINRNSIKRSSLVANPGCYPTASLLGLWPVISENLINLNTIIIDAKSG
HHHHHHHHHHHHEECCHHHHHHHEECCCCCCCHHHHHHHHHHHHCCEEEEEEEEEECCCC
VSGAGKGLKRGSHFVEVDENIKGYSIGSHRHTSEIEEIIKTFSGNQKAIVSFTPHLVPMK
CCCCCCHHHCCCCEEEECCCCCCEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHH
RGILATIYVKLKQSISERALRELYHKYYPDHGFIKVLPRDIFPETKYVVGTNYCYIGLKY
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHCCCCCCEEEECCEEEEEEEE
DTRTERLVIISAIDNLVKGAAGQAIQNMNVMFNLPEYMGLKQVGVFP
CCCCCEEEEEHHHHHHHHCHHHHHHHCCCEEEECHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA