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The map label for this gene is gcp [H]

Identifier: 220931047

GI number: 220931047

Start: 203209

End: 204225

Strand: Direct

Name: gcp [H]

Synonym: Hore_01980

Alternate gene names: 220931047

Gene position: 203209-204225 (Clockwise)

Preceding gene: 220931046

Following gene: 220931048

Centisome position: 7.88

GC content: 43.17

Gene sequence:

>1017_bases
ATGAAGAATAAAAATGTTATTATTCTGGCAATAGAGACATCCTGTGACGAGACTGCAGCTGCAGTTGTGAAAAATGGGGT
TGAAGTTCTGTCCAATATTGTGGCCTCTCAGGTAGACTGGCACCGTAAATATGGTGGGGTTGTCCCTGAAATAGCATCCC
GGAAACACCTGGAATTTATTAATCCTGTGGTCAAAGAAGCCCTTGACAGGGCGGGTCTGACCTTCAAGGATTTAGATGCA
GTAGCCTGTACCTATGGACCAGGATTGGTAGGTGGCCTTTTAGTTGGGTTATCGGCGGCAAAGGCAATTGCTTATGCTAC
CGGTAAACCATTTATCGGAGTTAATCATATTGCCGGACATATTTACGCCAATTTCATATCCCATAATGATATTGAACTCC
CGGCTGCCTGTCTTACTATTTCTGGTGGTCATACGGATCTTTTATATTTTAAAAATCGCGGGGAGTATAAAATACTGGGG
CGGACCCGTGATGATGCGGCCGGTGAAGCCTTTGATAAAACAGCCCGGGTCCTGAAACTGGGATATCCCGGGGGGCCGGC
CATTGAAAAGGCAGCCAGGGATGGAAATCCCCGTGCTGTAGATTTTCCCCGCCCTTTTCTGGAAAAGGATACTTTTGATT
TCAGTTTTAGTGGTTTAAAGACAGCTGTAATCAACTATATTCATAATAGAAAACAGCGTGGCCAGGAGATAAATGTCAAT
GATGTGGCAGCAGGCTTTCAACAGGCTGTTATTGATGTTTTGGTCAGTAAAGTTATAAAAGTGACAAAAAAATTACCCGT
AAAGAGTGTTATCCTGTCAGGTGGGGTGGCGGCCAATCGGTCTTTAAGATCACAGCTTCAAAAAGAATTAAATTACAGGA
ATATCCCCCTTTATTACCCCAGGCTCGAGTACTGTACCGATAATGCAGCAATGATAGGAGTAGTGGCTTATTACCAGTAC
CTGAAGGGTGATTTTAACGATTTAAGTTTAAATGCAGAAGCCAATTTAAAATTATAA

Upstream 100 bases:

>100_bases
AGGCTTTATGAGAAGCTAGGATTTATTCCTATTGGCTGTTATGTTGGTTATTATAAGAATAATAATGAGGATGCTCTGGT
TATGTGGAAGGGGTTAAAAA

Downstream 100 bases:

>100_bases
GTGGGGCGAGGTAGTAGTATGAAGATAGAGGGTAAACATAAATATCTTTTATTAAAAACGGTTCAGGAAGATGGGATCCT
TCCCCTTACTTCGGTCTGTA

Product: putative metalloendopeptidase, glycoprotease family

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKNKNVIILAIETSCDETAAAVVKNGVEVLSNIVASQVDWHRKYGGVVPEIASRKHLEFINPVVKEALDRAGLTFKDLDA
VACTYGPGLVGGLLVGLSAAKAIAYATGKPFIGVNHIAGHIYANFISHNDIELPAACLTISGGHTDLLYFKNRGEYKILG
RTRDDAAGEAFDKTARVLKLGYPGGPAIEKAARDGNPRAVDFPRPFLEKDTFDFSFSGLKTAVINYIHNRKQRGQEINVN
DVAAGFQQAVIDVLVSKVIKVTKKLPVKSVILSGGVAANRSLRSQLQKELNYRNIPLYYPRLEYCTDNAAMIGVVAYYQY
LKGDFNDLSLNAEANLKL

Sequences:

>Translated_338_residues
MKNKNVIILAIETSCDETAAAVVKNGVEVLSNIVASQVDWHRKYGGVVPEIASRKHLEFINPVVKEALDRAGLTFKDLDA
VACTYGPGLVGGLLVGLSAAKAIAYATGKPFIGVNHIAGHIYANFISHNDIELPAACLTISGGHTDLLYFKNRGEYKILG
RTRDDAAGEAFDKTARVLKLGYPGGPAIEKAARDGNPRAVDFPRPFLEKDTFDFSFSGLKTAVINYIHNRKQRGQEINVN
DVAAGFQQAVIDVLVSKVIKVTKKLPVKSVILSGGVAANRSLRSQLQKELNYRNIPLYYPRLEYCTDNAAMIGVVAYYQY
LKGDFNDLSLNAEANLKL
>Mature_338_residues
MKNKNVIILAIETSCDETAAAVVKNGVEVLSNIVASQVDWHRKYGGVVPEIASRKHLEFINPVVKEALDRAGLTFKDLDA
VACTYGPGLVGGLLVGLSAAKAIAYATGKPFIGVNHIAGHIYANFISHNDIELPAACLTISGGHTDLLYFKNRGEYKILG
RTRDDAAGEAFDKTARVLKLGYPGGPAIEKAARDGNPRAVDFPRPFLEKDTFDFSFSGLKTAVINYIHNRKQRGQEINVN
DVAAGFQQAVIDVLVSKVIKVTKKLPVKSVILSGGVAANRSLRSQLQKELNYRNIPLYYPRLEYCTDNAAMIGVVAYYQY
LKGDFNDLSLNAEANLKL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=328, Percent_Identity=35.9756097560976, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI8923380, Length=324, Percent_Identity=29.0123456790123, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1789445, Length=331, Percent_Identity=43.5045317220544, Blast_Score=278, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17557464, Length=329, Percent_Identity=31.9148936170213, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=331, Percent_Identity=28.7009063444109, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6320099, Length=340, Percent_Identity=32.0588235294118, Blast_Score=143, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6322891, Length=322, Percent_Identity=26.7080745341615, Blast_Score=89, Evalue=7e-19,
Organism=Drosophila melanogaster, GI20129063, Length=347, Percent_Identity=31.9884726224784, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21357207, Length=323, Percent_Identity=29.4117647058824, Blast_Score=121, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36828; Mature: 36828

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKNVIILAIETSCDETAAAVVKNGVEVLSNIVASQVDWHRKYGGVVPEIASRKHLEFI
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHH
NPVVKEALDRAGLTFKDLDAVACTYGPGLVGGLLVGLSAAKAIAYATGKPFIGVNHIAGH
HHHHHHHHHHCCCCHHHCCHHHEECCCHHHHHHHHHHHHHHHHHEECCCCCEEHHHHHHH
IYANFISHNDIELPAACLTISGGHTDLLYFKNRGEYKILGRTRDDAAGEAFDKTARVLKL
HHHHHHCCCCCCCCEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHEEEE
GYPGGPAIEKAARDGNPRAVDFPRPFLEKDTFDFSFSGLKTAVINYIHNRKQRGQEINVN
CCCCCHHHHHHHCCCCCCEECCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
DVAAGFQQAVIDVLVSKVIKVTKKLPVKSVILSGGVAANRSLRSQLQKELNYRNIPLYYP
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEECC
RLEYCTDNAAMIGVVAYYQYLKGDFNDLSLNAEANLKL
CHHHCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MKNKNVIILAIETSCDETAAAVVKNGVEVLSNIVASQVDWHRKYGGVVPEIASRKHLEFI
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHH
NPVVKEALDRAGLTFKDLDAVACTYGPGLVGGLLVGLSAAKAIAYATGKPFIGVNHIAGH
HHHHHHHHHHCCCCHHHCCHHHEECCCHHHHHHHHHHHHHHHHHEECCCCCEEHHHHHHH
IYANFISHNDIELPAACLTISGGHTDLLYFKNRGEYKILGRTRDDAAGEAFDKTARVLKL
HHHHHHCCCCCCCCEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHEEEE
GYPGGPAIEKAARDGNPRAVDFPRPFLEKDTFDFSFSGLKTAVINYIHNRKQRGQEINVN
CCCCCHHHHHHHCCCCCCEECCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
DVAAGFQQAVIDVLVSKVIKVTKKLPVKSVILSGGVAANRSLRSQLQKELNYRNIPLYYP
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEECC
RLEYCTDNAAMIGVVAYYQYLKGDFNDLSLNAEANLKL
CHHHCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA