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The map label for this gene is acpS

Identifier: 220931015

GI number: 220931015

Start: 171770

End: 172147

Strand: Direct

Name: acpS

Synonym: Hore_01660

Alternate gene names: 220931015

Gene position: 171770-172147 (Clockwise)

Preceding gene: 220931014

Following gene: 220931016

Centisome position: 6.66

GC content: 35.98

Gene sequence:

>378_bases
GTGATTAGGGGAATTGGAATTGATATTGTTGAAGTCAATAGAATAAGTGATATGGTGGACAAATGGGGAGAACGCTTTTT
AAATAAGGTATATACCCCTTATGAAGTTAATTATTGCAAATTTAAATCCAATACTTATGAGTGTCTGGCCGGTAGATTTG
CTGCTAAAGAGGCCTTTGTGAAAATGCTGGGAACAGGATTTAAGCATATCTATTTTAAAGACATAGAAGTTCGTTCTGAT
GAAAAGGGTAAGCCTTATTTACGGATAAAAGGGAATGCCGATAGATTGACAAAGGAATCAGGTATAAAAAGGATACATTT
AAGTATATCCCATGAGCGGAAATTTGCGATAGCTTTTGTAGTTGGTGAGGAGGGGTAA

Upstream 100 bases:

>100_bases
AGGAAGGTGACCGGGCCTGAATTGAGGTCCGGATTTTTGCATTTGCCGGGGAGTTACAGTATAATTAAATTGGATATAAT
TGATGTTAGGAGAATTACCT

Downstream 100 bases:

>100_bases
CAGTGGTTGTACTTACACCCGGGCAGATGAGGAAAGCAGATCAGCTGGCCATCAAAGCAGGAATCCCTGACCTGGTCTTA
ATGGAGGTAGCCGGGAGGGA

Product: Holo-(acyl-carrier-protein) synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MIRGIGIDIVEVNRISDMVDKWGERFLNKVYTPYEVNYCKFKSNTYECLAGRFAAKEAFVKMLGTGFKHIYFKDIEVRSD
EKGKPYLRIKGNADRLTKESGIKRIHLSISHERKFAIAFVVGEEG

Sequences:

>Translated_125_residues
MIRGIGIDIVEVNRISDMVDKWGERFLNKVYTPYEVNYCKFKSNTYECLAGRFAAKEAFVKMLGTGFKHIYFKDIEVRSD
EKGKPYLRIKGNADRLTKESGIKRIHLSISHERKFAIAFVVGEEG
>Mature_125_residues
MIRGIGIDIVEVNRISDMVDKWGERFLNKVYTPYEVNYCKFKSNTYECLAGRFAAKEAFVKMLGTGFKHIYFKDIEVRSD
EKGKPYLRIKGNADRLTKESGIKRIHLSISHERKFAIAFVVGEEG

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=123, Percent_Identity=38.2113821138211, Blast_Score=84, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325025, Length=123, Percent_Identity=32.520325203252, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_HALOH (B8D0V9)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002507923.1
- ProteinModelPortal:   B8D0V9
- SMR:   B8D0V9
- GeneID:   7313294
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_01660
- HOGENOM:   HBG734479
- OMA:   NSSAIAY
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14429; Mature: 14429

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRGIGIDIVEVNRISDMVDKWGERFLNKVYTPYEVNYCKFKSNTYECLAGRFAAKEAFV
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEECEEEEECCCCHHHHHHHHHHHHHHH
KMLGTGFKHIYFKDIEVRSDEKGKPYLRIKGNADRLTKESGIKRIHLSISHERKFAIAFV
HHHCCCCCEEEEEEEEECCCCCCCCEEEEECCHHHHHHHCCCEEEEEEECCCCEEEEEEE
VGEEG
EECCC
>Mature Secondary Structure
MIRGIGIDIVEVNRISDMVDKWGERFLNKVYTPYEVNYCKFKSNTYECLAGRFAAKEAFV
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEECEEEEECCCCHHHHHHHHHHHHHHH
KMLGTGFKHIYFKDIEVRSDEKGKPYLRIKGNADRLTKESGIKRIHLSISHERKFAIAFV
HHHCCCCCEEEEEEEEECCCCCCCCEEEEECCHHHHHHHCCCEEEEEEECCCCEEEEEEE
VGEEG
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA