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The map label for this gene is coaX

Identifier: 220930916

GI number: 220930916

Start: 80027

End: 80800

Strand: Direct

Name: coaX

Synonym: Hore_00680

Alternate gene names: 220930916

Gene position: 80027-80800 (Clockwise)

Preceding gene: 220930915

Following gene: 220930917

Centisome position: 3.1

GC content: 40.96

Gene sequence:

>774_bases
ATGATATTGGCAATTGATGTCGGAAATACTAACACAGTGATGGGTATCTATAAAAAAGATAAATTGATTCAGCACTGGCG
TATTTCCACTGATAAAAATAAAACACCTGATGAATATGGTATCTTGTTTTTGAATCTCTTTAATTCGGCCAATGTAAATT
ATAAAAGAATAGACGGAATTATACTTTCCAGTGTAGTTCCTCCTCTGGTAAGAATATTGAAGAAGATGACAACACGGTAT
TTTAATTTAGAACCACTGGTAGTAGGGCCCGGTATCAGGACCGGGATTAACTTAAAAATGGATAACCCCCGTGAGGTCGG
GGCCGACCAGGTAGTAAATGCAGTGGCAGCTTATCATAAATATGGTGGTCCCTTAATTATAGTTGACTTTGGTACCGCAA
CTACCTTCTGTGCTGTATCTGAACGGGGGGAATACCTCGGCGGGGCTATTGCGCCCGGTATTGGGATTTCAGCTGAAGCT
CTATATTCCTATGCTGCTAAATTGCCCCGGGTAGAATTTAAAACCCCCGGCCAGGCCATTGGAAAAAATACTGTTGCCGG
GATGCAGTCTGGTATTATATATGGGTTTGTCGGGTTAGTTGAGGCCCTTGTTAAAAGGTTTAAAGATGAGCTTAAGGAAA
CTCCTGAAGTTATTGCTACCGGGGGTCTGGTTAGTTTAATTGCATCTGAAACAGATGAAATTGATAAAGTAGATCCCTTT
TTAACCCTTGACGGACTCTACTATATTGCCAAAATAAACGGAATTGTGGAGTGA

Upstream 100 bases:

>100_bases
ATGTAGAATAATATCCCTGAATATCAAATATAATATATAGGTTTTGAAAAACAATAATATCAGGGGAGTTAAGGTAAAAA
TAAGGAAGGGGGAAGGATAA

Downstream 100 bases:

>100_bases
ATAACTTATGAAGATCGGCAACCTGATTGTAGAAAACCCCATTATCCTGGCTCCAATGGCAGGTGTTACTGATTATCCTT
TTCGTCAAATTTCCCGGGAA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MILAIDVGNTNTVMGIYKKDKLIQHWRISTDKNKTPDEYGILFLNLFNSANVNYKRIDGIILSSVVPPLVRILKKMTTRY
FNLEPLVVGPGIRTGINLKMDNPREVGADQVVNAVAAYHKYGGPLIIVDFGTATTFCAVSERGEYLGGAIAPGIGISAEA
LYSYAAKLPRVEFKTPGQAIGKNTVAGMQSGIIYGFVGLVEALVKRFKDELKETPEVIATGGLVSLIASETDEIDKVDPF
LTLDGLYYIAKINGIVE

Sequences:

>Translated_257_residues
MILAIDVGNTNTVMGIYKKDKLIQHWRISTDKNKTPDEYGILFLNLFNSANVNYKRIDGIILSSVVPPLVRILKKMTTRY
FNLEPLVVGPGIRTGINLKMDNPREVGADQVVNAVAAYHKYGGPLIIVDFGTATTFCAVSERGEYLGGAIAPGIGISAEA
LYSYAAKLPRVEFKTPGQAIGKNTVAGMQSGIIYGFVGLVEALVKRFKDELKETPEVIATGGLVSLIASETDEIDKVDPF
LTLDGLYYIAKINGIVE
>Mature_257_residues
MILAIDVGNTNTVMGIYKKDKLIQHWRISTDKNKTPDEYGILFLNLFNSANVNYKRIDGIILSSVVPPLVRILKKMTTRY
FNLEPLVVGPGIRTGINLKMDNPREVGADQVVNAVAAYHKYGGPLIIVDFGTATTFCAVSERGEYLGGAIAPGIGISAEA
LYSYAAKLPRVEFKTPGQAIGKNTVAGMQSGIIYGFVGLVEALVKRFKDELKETPEVIATGGLVSLIASETDEIDKVDPF
LTLDGLYYIAKINGIVE

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_HALOH (B8D075)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002507824.1
- ProteinModelPortal:   B8D075
- SMR:   B8D075
- GeneID:   7314286
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_00680
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27917; Mature: 27917

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILAIDVGNTNTVMGIYKKDKLIQHWRISTDKNKTPDEYGILFLNLFNSANVNYKRIDGI
CEEEEEECCCCEEEEEEHHHHHHHHHCCCCCCCCCCHHHCEEEEEEECCCCCCHHHHHHH
ILSSVVPPLVRILKKMTTRYFNLEPLVVGPGIRTGINLKMDNPREVGADQVVNAVAAYHK
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCHHCCHHHHHHHHHHHHH
YGGPLIIVDFGTATTFCAVSERGEYLGGAIAPGIGISAEALYSYAAKLPRVEFKTPGQAI
CCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHH
GKNTVAGMQSGIIYGFVGLVEALVKRFKDELKETPEVIATGGLVSLIASETDEIDKVDPF
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHCCCCCHHCCCCE
LTLDGLYYIAKINGIVE
EEECCEEEEEEECCCCC
>Mature Secondary Structure
MILAIDVGNTNTVMGIYKKDKLIQHWRISTDKNKTPDEYGILFLNLFNSANVNYKRIDGI
CEEEEEECCCCEEEEEEHHHHHHHHHCCCCCCCCCCHHHCEEEEEEECCCCCCHHHHHHH
ILSSVVPPLVRILKKMTTRYFNLEPLVVGPGIRTGINLKMDNPREVGADQVVNAVAAYHK
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCHHCCHHHHHHHHHHHHH
YGGPLIIVDFGTATTFCAVSERGEYLGGAIAPGIGISAEALYSYAAKLPRVEFKTPGQAI
CCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHH
GKNTVAGMQSGIIYGFVGLVEALVKRFKDELKETPEVIATGGLVSLIASETDEIDKVDPF
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHCCCCCHHCCCCE
LTLDGLYYIAKINGIVE
EEECCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA